Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions

Journal of Cellular Physiology

Volumn 227, Issue 6, 2012, Pages 2352-2362

  Miranda, Soledad ^a,b   González Rodríguez, Águeda ^a,b   García Ramírez, Marta ^b,c   Revuelta Cervantes, Jesús ^a,b   Hernández, Cristina ^b,c   Simó, Rafael ^b,c   Valverde, Ángela M ^a,b  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FENOFIBRATE; GLUCOSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGEN; PROTEIN BCL XL; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C RECEPTOR; STRESS ACTIVATED PROTEIN KINASE;

AGED; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CULTURE; CELL DISRUPTION; CELL HYPOXIA; CELL IMMORTALIZATION; CELL PROTECTION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS; DIABETIC RETINOPATHY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; PIGMENT CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TIGHT JUNCTION;

AGED; APOPTOSIS; AUTOPHAGY; BCL-X PROTEIN; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD-RETINAL BARRIER; CASE-CONTROL STUDIES; CASPASE 3; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; DIABETIC RETINOPATHY; EIF-2 KINASE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; FENOFIBRATE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERMEABILITY; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RECEPTOR, IGF TYPE 1; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TIME FACTORS; TRANSCRIPTION FACTOR CHOP;

EID: 84857470005     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22970     Document Type: Article

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