β-Caryophyllene potently inhibits solid tumor growth and lymph node metastasis of B16F10 melanoma cells in high-fat diet-induced obese C57BL/6N mice

Carcinogenesis

Volumn 36, Issue 9, 2015, Pages 1028-1039

  Jung, Jae In ^a   Kim, Eun Ji ^a   Kwon, Gyoo Taik ^a   Jung, Yoo Jin ^a   Park, Taesung ^b   Kim, Yongkang ^b   Yu, Rina ^c   Choi, Myung Sook ^d   Chun, Hyang Sook ^e   Kwon, Seung Hae ^f   Her, Song ^f   Lee, Ki Won ^g,h   Park, Jung Han Yoon ^a,h  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

^c University of Ulsan   (South Korea)

^d Kyungpook National University   (South Korea)

^e Chung Ang University   (South Korea)

^f Korea Basic Science Institute (KBSI)   (South Korea)

^g Seoul National University   (South Korea)

^h Seoul National University   (South Korea)

Author keywords

Diet induced obese mouse model; Lymphangiogenesis; Macrophage infiltration; Metastasis; Tumor growth; Caryophyllene

Indexed keywords

CARYOPHYLLENE; CHEMOKINE RECEPTOR CCR7; GLUCOSE; LIPID; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MANNOSE RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; SECONDARY LYMPHOID TISSUE CHEMOKINE; ANTINEOPLASTIC AGENT; CCL19 PROTEIN, MOUSE; CCL2 PROTEIN, MOUSE; CCR7 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; FAT INTAKE; LECTIN; MANNOSE BINDING LECTIN; SESQUITERPENE;

3T3 CELL LINE; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER TISSUE; CELL VACUOLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; LEUKOCYTE MIGRATION; LIPID STORAGE; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; MACROPHAGE; MALE; MELANOMA; MELANOMA METASTASIS; METASTASIS INHIBITION; MONOCYTE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT GAIN; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BODY WEIGHT; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; FAT INTAKE; LIPID DIET; LYMPH NODE; MELANOMA, EXPERIMENTAL; METABOLISM; MOUSE MUTANT; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; RANDOMIZATION; SECRETION (PROCESS); SKIN NEOPLASMS; SUBCUTANEOUS FAT; TUMOR CELL LINE;

3T3 CELLS; ADIPOCYTES; ANIMALS; ANTINEOPLASTIC AGENTS; BODY WEIGHT; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CCL19; CHEMOKINE CCL2; CHEMOKINE CCL21; DIET, HIGH-FAT; DIETARY FATS; LECTINS, C-TYPE; LYMPH NODES; LYMPHATIC METASTASIS; MACROPHAGES; MALE; MANNOSE-BINDING LECTINS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, OBESE; NEOVASCULARIZATION, PATHOLOGIC; OBESITY; RANDOM ALLOCATION; RECEPTORS, CCR7; RECEPTORS, CELL SURFACE; SESQUITERPENES; SKIN NEOPLASMS; SUBCUTANEOUS FAT; VACUOLES; WEIGHT GAIN;

EID: 84940657206     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv076     Document Type: Article

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