Minocycline inhibits PARP-1 expression and decreases apoptosis in diabetic retinopathy

Molecular Medicine Reports

Volumn 12, Issue 4, 2015, Pages 4887-4894

  Wu, Ying ^a   Chen, Yongdong ^b   Wu, Qiang ^b   Jia, Lili ^b   Du, Xinhua ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

Author keywords

Apoptosis; Diabetic retinopathy; Electroretinogram; Minocycline; Poly (ADP ribose) polymerase 1

Indexed keywords

CASPASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; EOSIN; GLUCOSE; HEMATOXYLIN; MESSENGER RNA; MINOCYCLINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); STREPTOZOCIN; CASP3 PROTEIN, RAT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG EFFECT; DRUG INHIBITION; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN EXPRESSION; RANDOMIZATION; RAT; RETINA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNEL ASSAY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RETINA; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CASPASE 3; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MALE; MINOCYCLINE; POLY (ADP-RIBOSE) POLYMERASE-1; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; RETINA; STREPTOZOCIN;

EID: 84940547038     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4064     Document Type: Article

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