The multifocal ERG in diabetic patients without retinopathy during euglycemic clamping

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 7, 2005, Pages 2620-2626

  Klemp, Kristian ^a,d   Sander, Birgit ^a   Brockhoff, Per Bruun ^b   Vaag, Allan ^c   Lund Andersen, Henrik ^a   Larsen, Michael ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c STENO DIABETES CENTER   (Denmark)

^d GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAM; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PRIORITY JOURNAL; RETINOPATHY; DIABETIC RETINOPATHY; ELECTRORETINOGRAPHY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; ELECTRORETINOGRAPHY; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPERGLYCEMIA; MALE; RETINA;

EID: 23244438206     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-1254     Document Type: Article

References (39)

1. Barber AJ, Antonetti DA, Gardner TW. Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group. Invest Ophthalmol Vis Sci. 2000;41:3561-3568.
2. Mizutani M, Gerhardinger C, Lorenzi M. Müller cell changes in human diabetic retinopathy. Diabetes. 1998;47:445-449.
3. Roy MS, Gunkel RD, Podgor MJ. Color vision defects in early diabetic retinopathy. Arch Ophthalmol. 1986;104:225-228.
4. Hardy KJ, Lipton J, Scase MO, et al. Detection of colour vision abnormalities in uncomplicated type 1 diabetic patients with angiographically normal retinas. Br J Ophthalmol. 1992;76:461-464.
5. Trick GL, Burde RM, Gordon MO, et al. The relationship between hue discrimination and contrast sensitivity deficits in patients with diabetes mellitus. Ophthalmology. 1988;95:693-698.
6. Di Leo MA, Caputo S, Falsini B, et al. Nonselective loss of contrast sensitivity in visual system testing in early type I diabetes. Diabetes Care. 1992;15:620-625.
7. Galloway NR, Wells M, Barber C. Changes in the oscillatory potential in relation to different types diabetic retinography. Vision Res. 1971;11:1218-1223.
8. Parisi V, Uccioli L. Visual electrophysiological responses in persons with type 1 diabetes. Diabetes Metab Res Rev. 2001;17:12-18.
9. Brunette JR, Lafond G. Electroretinographic evaluation of diabetic retinopathy: sensitivity of amplitude and time of response. Can J Ophthalmol. 1983;18:285-289.
10. Holopigian K, Seiple W, Lorenzo M, et al. A comparison of photopic and scotopic electroretinographic changes in early diabetic retinopathy. Invest Ophthalmol Vis Sci. 1992;33:2773-2780.
11. Bresnick GH, Palta M. Oscillatory potential amplitudes: relation to severity of diabetic retinopathy. Arch Ophthalmol. 1987;105:929-933.
12. Bresnick GH, Palta M. Predicting progression to severe proliferative diabetic retinopathy. Arch Ophthalmol. 1987;105:810-814.
13. Simonsen SE. The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy. Acta Ophthalmol (Copenh). 1980;58:865-878.
14. Wanger P, Persson HE. Early diagnosis of retinal changes in diabetes: a comparison between electroretinography and retinal biomicroscopy. Acta Ophthalmol (Copenh). 1985;63:716-720.
15. Birch D. Focal electroretinography. In: Heckenlively GB, Arden JR, ed. Principles and Practice of Clinical Electrophysiology of Vision. St. Louis: Mosby; 1991:334-338.
16. Sutler EE, Tran D. The field topography of ERG components in man. I. The photopic luminance response. Vision Res. 1992;32: 433-446.
17. Palmowski AM, Sutler EE, Bearse MA Jr, et al. Mapping of retinal function in diabetic retinopathy using the multifocal electroretinogram. Invest Ophthalmol Vis Sci. 1997;38:2586-2596.
18. Fortune B, Schneck ME, Adams AJ. Multifocal electroretinogram delays reveal local retinal dysfunction in early diabetic retinopathy. Invest Ophthalmol Vis Sci. 1999;40:2638-2651.
19. Greenstein VC, Holopigian K, Hood DC, et al. The nature and extent of retinal dysfunction associated with diabetic macular edema. Invest Ophthalmol Vis Sci. 2000;41:3643-3654.
20. Greenstein VC, Chen H, Hood DC, et al. Retinal function in diabetic macular edema after focal laser photocoagulation. Invest Ophthalmol Vis Sci. 2000;41:3655-3664.
21. Bearse MA Jr, Han Y, Schneck ME, et al. Retinal function in normal and diabetic eyes mapped with the slow flash multifocal electroretinogram. Invest Ophthalmol Vis Sci. 2004;45:296-304.
22. Kurtenbach A, Langrova H, Zrenner E. Multifocal oscillatory potentials in type 1 diabetes without retinopathy. Invest Ophthalmol Vis Sci. 2000;41:3234-3241.
23. Shimada Y, Li Y, Bearse MA Jr, et al. Assessment of early retinal changes in diabetes using a new multifocal ERG protocol. Br J Ophthalmol. 2001;85:414-419.
24. Han Y, Adams AJ, Bearse MA Jr, et al. Multifocal electroretinogram and short-wavelength automated perimetry measures in diabetic eyes with little or no retinopathy. Arch Ophthalmol. 2004;122: 1809-1815.
25. Han Y, Bearse MA Jr, Schneck ME, et al. Towards optimal filtering of "standard" multifocal electroretinogram (mfERG) recordings: findings in normal and diabetic subjects. Br J Ophthalmol. 2004; 88:543-550.
26. Han Y, Bearse MA Jr, Schneck ME, et al. Multifocal electroretinogram delays predict sites of subsequent diabetic retinopathy. Invest Ophthalmol Vis Sci. 2004;45:948-954.
27. Han Y, Schneck ME, Bearse MA Jr, et al. Formulation and evaluation of a predictive model to identify the sites of future diabetic retinopathy. Invest Ophthalmol Vis Sci. 2004;45:4106-4112.
28. Klemp K, Larsen M, Sander B, et al. Effect of short-term hyperglycemia on multifocal electroretinogram in diabetic patients without retinopathy. Invest Ophthalmol Vis Sci. 2004;45:3812-3819.
29. Bearse MA Jr, Han Y, Schneck ME, et al. Local multifocal oscillatory potential abnormalities in diabetes and early diabetic retinopathy. Invest Ophthalmol Vis Sci. 2004;45:3259-3265.
30. Dawson WW, Hazariwala K, Karges S. Human photopic response to circulating glucose. Doc Ophthalmol. 2000;101:155-163.
31. Marmor MF, Hood DC, Keating D, et al. Guidelines for basic multifocal electroretinography (mfERG). Doc Ophthalmol. 2003; 106:105-115.
32. Littell RC, Milliken GA, Stroup WW, et al. SAS System for Mixed Models. Cary, NC: SAS Institute Inc.; 1996.
33. Rohlfing CL, Wiedmeyer HM, Little RR, et al. Defining the relationship between plasma glucose and HbA(1c): analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial. Diabetes Care. 2002;25:275-278.
34. Lansel N, Niemeyer G. Effects of insulin under normal and low glucose on retinal electrophysiology in the perfused cat eye. Invest Ophthalmol Vis Sci. 1997;38:792-799.
35. Hankins MW, Jones RJ, Ruddock KH. Diurnal variation in the b-wave implicit time of the human electroretinogram. Vis Neurosci. 1998;15:55-67.
36. Heinemann-Vernaleken B, Palmowski A, Allgayer R. The effect of time of day and repeat reliability on the fast flicker multifocal ERG. Doc Ophthalmol. 2000;101:247-255.
37. Coupland SG. A comparison of oscillatory potential and pattern electroretinogram measures in diabetic retinopathy. Doc Ophthalmol. 1987;66:207-218.
38. Barber AJ, Lieth E, Khin SA, et al. Neural apoptosis in the retina during experimental and human diabetes: early onset and effect of insulin. J Clin Invest. 1998;102:783-791.
39. The Diabetic Control and Complications Trial Research Group. Early worsening of diabetic retinopathy in the Diabetes Control and Complications Trial. Arch Ophthalmol. 1998;116:874-886