메뉴 건너뛰기




Volumn 16, Issue 9, 2015, Pages e460-e469

Inherited cylindromas: Lessons from a rare tumour

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN CYLD; TUMOR PROTEIN; UNCLASSIFIED DRUG; CYLD PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

EID: 84940533732     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(15)00245-4     Document Type: Review
Times cited : (41)

References (78)
  • 2
    • 72749085283 scopus 로고    scopus 로고
    • Tumor mapping in 2 large multigenerational families with CYLD mutations: implications for disease management and tumor induction
    • Rajan N, Langtry JA, Ashworth A, et al. Tumor mapping in 2 large multigenerational families with CYLD mutations: implications for disease management and tumor induction. Arch Dermatol 2009, 145:1277-1284.
    • (2009) Arch Dermatol , vol.145 , pp. 1277-1284
    • Rajan, N.1    Langtry, J.A.2    Ashworth, A.3
  • 3
    • 0028788975 scopus 로고
    • Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene
    • Biggs PJ, Wooster R, Ford D, et al. Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene. Nat Genet 1995, 11:441-443.
    • (1995) Nat Genet , vol.11 , pp. 441-443
    • Biggs, P.J.1    Wooster, R.2    Ford, D.3
  • 4
    • 18844464056 scopus 로고    scopus 로고
    • Identification of the familial cylindromatosis tumour-suppressor gene
    • Bignell GR, Warren W, Seal S, et al. Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet 2000, 25:160-165.
    • (2000) Nat Genet , vol.25 , pp. 160-165
    • Bignell, G.R.1    Warren, W.2    Seal, S.3
  • 5
    • 0015043748 scopus 로고
    • Mutation and cancer: statistical study of retinoblastoma
    • Knudson AG Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971, 68:820-823.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 6
    • 0042467554 scopus 로고    scopus 로고
    • Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
    • Brummelkamp TR, Nijman SM, Dirac AM, Bernards R Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 2003, 424:797-801.
    • (2003) Nature , vol.424 , pp. 797-801
    • Brummelkamp, T.R.1    Nijman, S.M.2    Dirac, A.M.3    Bernards, R.4
  • 8
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
    • Trompouki E, Hatzivassiliou E, Tsichritzis T, Farmer H, Ashworth A, Mosialos G CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 2003, 424:793-796.
    • (2003) Nature , vol.424 , pp. 793-796
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3    Farmer, H.4    Ashworth, A.5    Mosialos, G.6
  • 9
    • 80455174799 scopus 로고    scopus 로고
    • GLI1-dependent transcriptional repression of CYLD in basal cell carcinoma
    • Kuphal S, Shaw-Hallgren G, Eberl M, et al. GLI1-dependent transcriptional repression of CYLD in basal cell carcinoma. Oncogene 2011, 30:4523-4530.
    • (2011) Oncogene , vol.30 , pp. 4523-4530
    • Kuphal, S.1    Shaw-Hallgren, G.2    Eberl, M.3
  • 10
    • 77954310807 scopus 로고    scopus 로고
    • Ubiquitin chain cleavage: CYLD at work
    • Massoumi R Ubiquitin chain cleavage: CYLD at work. Trends Biochem Sci 2010, 35:392-399.
    • (2010) Trends Biochem Sci , vol.35 , pp. 392-399
    • Massoumi, R.1
  • 11
    • 0021267008 scopus 로고
    • Dermal cylindromas originate from the eccrine sweat gland
    • Cotton DW, Braye SG Dermal cylindromas originate from the eccrine sweat gland. Br J Dermatol 1984, 111:53-61.
    • (1984) Br J Dermatol , vol.111 , pp. 53-61
    • Cotton, D.W.1    Braye, S.G.2
  • 12
    • 0032990120 scopus 로고    scopus 로고
    • Spiradenocylindromas of the skin: tumors with morphological features of spiradenoma and cylindroma in the same lesion: report of 12 cases
    • Michal M, Lamovec J, Mukensnabl P, Pizinger K Spiradenocylindromas of the skin: tumors with morphological features of spiradenoma and cylindroma in the same lesion: report of 12 cases. Pathol Int 1999, 49:419-425.
    • (1999) Pathol Int , vol.49 , pp. 419-425
    • Michal, M.1    Lamovec, J.2    Mukensnabl, P.3    Pizinger, K.4
  • 13
    • 3142512147 scopus 로고
    • Turban tumour
    • Evans CD Turban tumour. Br J Dermatol 1954, 66:434-443.
    • (1954) Br J Dermatol , vol.66 , pp. 434-443
    • Evans, C.D.1
  • 14
    • 0019864666 scopus 로고
    • Florid dermal cylindroma (turban tumor)
    • Fabian RL, Shugar MA Florid dermal cylindroma (turban tumor). Head Neck Surg 1981, 4:165-169.
    • (1981) Head Neck Surg , vol.4 , pp. 165-169
    • Fabian, R.L.1    Shugar, M.A.2
  • 15
    • 79961207791 scopus 로고    scopus 로고
    • Recurrent CYLD nonsense mutation associated with a severe, disfiguring phenotype in an African American family with multiple familial trichoepithelioma
    • Linos K, Schwartz J, Kazakov DV, Vanecek T, Carlson JA Recurrent CYLD nonsense mutation associated with a severe, disfiguring phenotype in an African American family with multiple familial trichoepithelioma. Am J Dermatopathol 2011, 33:640-642.
    • (2011) Am J Dermatopathol , vol.33 , pp. 640-642
    • Linos, K.1    Schwartz, J.2    Kazakov, D.V.3    Vanecek, T.4    Carlson, J.A.5
  • 16
    • 84873412724 scopus 로고    scopus 로고
    • Novel and recurrent germline and somatic mutations in a cohort of 67 patients from 48 families with Brooke-Spiegler syndrome including the phenotypic variant of multiple familial trichoepitheliomas and correlation with the histopathologic findings in 379 biopsy specimens
    • Grossmann P, Vanecek T, Steiner P, et al. Novel and recurrent germline and somatic mutations in a cohort of 67 patients from 48 families with Brooke-Spiegler syndrome including the phenotypic variant of multiple familial trichoepitheliomas and correlation with the histopathologic findings in 379 biopsy specimens. Am J Dermatopathol 2013, 35:34-44.
    • (2013) Am J Dermatopathol , vol.35 , pp. 34-44
    • Grossmann, P.1    Vanecek, T.2    Steiner, P.3
  • 18
    • 0025864806 scopus 로고
    • Cylindroma overexpresses collagen VII, the major anchoring fibril protein
    • Bruckner-Tuderman L, Pfaltz M, Schnyder UW Cylindroma overexpresses collagen VII, the major anchoring fibril protein. J Invest Dermatol 1991, 96:729-734.
    • (1991) J Invest Dermatol , vol.96 , pp. 729-734
    • Bruckner-Tuderman, L.1    Pfaltz, M.2    Schnyder, U.W.3
  • 19
    • 0036174017 scopus 로고    scopus 로고
    • Defective laminin 5 processing in cylindroma cells
    • Tunggal L, Ravaux J, Pesch M, et al. Defective laminin 5 processing in cylindroma cells. Am J Pathol 2002, 160:459-468.
    • (2002) Am J Pathol , vol.160 , pp. 459-468
    • Tunggal, L.1    Ravaux, J.2    Pesch, M.3
  • 20
    • 79958214511 scopus 로고    scopus 로고
    • Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression
    • Rajan N, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression. J Pathol 2011, 224:309-321.
    • (2011) J Pathol , vol.224 , pp. 309-321
    • Rajan, N.1    Burn, J.2    Langtry, J.3    Sieber-Blum, M.4    Lord, C.J.5    Ashworth, A.6
  • 21
    • 84857570226 scopus 로고    scopus 로고
    • Epithelial stem cells, wound healing and cancer
    • Arwert EN, Hoste E, Watt FM Epithelial stem cells, wound healing and cancer. Nat Rev Cancer 2012, 12:170-180.
    • (2012) Nat Rev Cancer , vol.12 , pp. 170-180
    • Arwert, E.N.1    Hoste, E.2    Watt, F.M.3
  • 22
    • 0000943419 scopus 로고
    • Dermal cylindroma (dermal eccrine cylindroma)
    • Crain RC, Helwig EB Dermal cylindroma (dermal eccrine cylindroma). Am J Clin Pathol 1961, 35:504-515.
    • (1961) Am J Clin Pathol , vol.35 , pp. 504-515
    • Crain, R.C.1    Helwig, E.B.2
  • 23
    • 84923310680 scopus 로고    scopus 로고
    • Spiradenoma and cylindroma originate from the hair follicle bulge and not from the eccrine sweat gland: an immunohistochemical study with CD200 and other stem cell markers
    • Sellheyer K Spiradenoma and cylindroma originate from the hair follicle bulge and not from the eccrine sweat gland: an immunohistochemical study with CD200 and other stem cell markers. J Cutan Pathol 2015, 42:90-101.
    • (2015) J Cutan Pathol , vol.42 , pp. 90-101
    • Sellheyer, K.1
  • 24
    • 33646531810 scopus 로고    scopus 로고
    • Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
    • Massoumi R, Chmielarska K, Hennecke K, Pfeifer A, Fässler R Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell 2006, 125:665-677.
    • (2006) Cell , vol.125 , pp. 665-677
    • Massoumi, R.1    Chmielarska, K.2    Hennecke, K.3    Pfeifer, A.4    Fässler, R.5
  • 25
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18:6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 26
    • 84940521307 scopus 로고
    • Die Nevenverteilung in derhant in ihrer Beziehung zuden Ekrankungender Haut
    • VII Congress; Breslan; May
    • Blaschko A. Die Nevenverteilung in derhant in ihrer Beziehung zuden Ekrankungender Haut. Verhand Deust Dermatol Gessel. VII Congress; Breslan; May 1901.
    • (1901) Verhand Deust Dermatol Gessel
    • Blaschko, A.1
  • 27
    • 0038693599 scopus 로고    scopus 로고
    • Pedigree of multiple benign adnexal tumours of Brooke-Spiegler type
    • Saunders H, Tucker P, Saurine T, Watkins F Pedigree of multiple benign adnexal tumours of Brooke-Spiegler type. Australas J Dermatol 2003, 44:144-148.
    • (2003) Australas J Dermatol , vol.44 , pp. 144-148
    • Saunders, H.1    Tucker, P.2    Saurine, T.3    Watkins, F.4
  • 28
    • 0030469111 scopus 로고    scopus 로고
    • Segmental forms of autosomal dominant skin disorders: different types of severity reflect different states of zygosity
    • Happle R Segmental forms of autosomal dominant skin disorders: different types of severity reflect different states of zygosity. Am J Med Genet 1996, 66:241-242.
    • (1996) Am J Med Genet , vol.66 , pp. 241-242
    • Happle, R.1
  • 29
    • 0017397116 scopus 로고
    • Membranous basal cell adenoma of parotid gland, dermal cylindromas, and trichoepitheliomas. Comparative histochemistry and ultrastructure
    • Headington JT, Batsakis JG, Beals TF, Campbell TE, Simmons JL, Stone WD Membranous basal cell adenoma of parotid gland, dermal cylindromas, and trichoepitheliomas. Comparative histochemistry and ultrastructure. Cancer 1977, 39:2460-2469.
    • (1977) Cancer , vol.39 , pp. 2460-2469
    • Headington, J.T.1    Batsakis, J.G.2    Beals, T.F.3    Campbell, T.E.4    Simmons, J.L.5    Stone, W.D.6
  • 30
    • 0032792416 scopus 로고    scopus 로고
    • Turban tumour with involvement of the parotid gland
    • Jungehülsing M, Wagner M, Damm M Turban tumour with involvement of the parotid gland. J Laryngol Otol 1999, 113:779-783.
    • (1999) J Laryngol Otol , vol.113 , pp. 779-783
    • Jungehülsing, M.1    Wagner, M.2    Damm, M.3
  • 31
    • 0023864649 scopus 로고
    • Membranous basal cell adenoma of the parotid gland. Malignant transformation in a patient with multiple dermal cylindromas
    • Hyman BA, Scheithauer BW, Weiland LH, Irons GB Membranous basal cell adenoma of the parotid gland. Malignant transformation in a patient with multiple dermal cylindromas. Arch Pathol Lab Med 1988, 112:209-211.
    • (1988) Arch Pathol Lab Med , vol.112 , pp. 209-211
    • Hyman, B.A.1    Scheithauer, B.W.2    Weiland, L.H.3    Irons, G.B.4
  • 33
  • 34
    • 0023771438 scopus 로고
    • Autosomal dominant multiple cylindromas associated with solitary lung cylindroma
    • Vernon HJ, Olsen EA, Vollmer RT Autosomal dominant multiple cylindromas associated with solitary lung cylindroma. J Am Acad Dermatol 1988, 19:397-400.
    • (1988) J Am Acad Dermatol , vol.19 , pp. 397-400
    • Vernon, H.J.1    Olsen, E.A.2    Vollmer, R.T.3
  • 39
    • 65449156802 scopus 로고    scopus 로고
    • Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome
    • Kazakov DV, Zelger B, Rütten A, et al. Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome. Am J Surg Pathol 2009, 33:705-719.
    • (2009) Am J Surg Pathol , vol.33 , pp. 705-719
    • Kazakov, D.V.1    Zelger, B.2    Rütten, A.3
  • 40
    • 13244298637 scopus 로고    scopus 로고
    • High-grade trichoblastic carcinoma arising in trichoblastoma: a rare adnexal neoplasm often showing metastatic spread
    • Schulz T, Proske S, Hartschuh W, Kurzen H, Paul E, Wünsch PH High-grade trichoblastic carcinoma arising in trichoblastoma: a rare adnexal neoplasm often showing metastatic spread. Am J Dermatopathol 2005, 27:9-16.
    • (2005) Am J Dermatopathol , vol.27 , pp. 9-16
    • Schulz, T.1    Proske, S.2    Hartschuh, W.3    Kurzen, H.4    Paul, E.5    Wünsch, P.H.6
  • 41
    • 84866139078 scopus 로고    scopus 로고
    • Basal cell carcinoma arising in association with trichoepithelioma in a case of Brooke-Spiegler syndrome with a novel genetic mutation in CYLD
    • Melly L, Lawton G, Rajan N Basal cell carcinoma arising in association with trichoepithelioma in a case of Brooke-Spiegler syndrome with a novel genetic mutation in CYLD. J Cutan Pathol 2012, 39:977-978.
    • (2012) J Cutan Pathol , vol.39 , pp. 977-978
    • Melly, L.1    Lawton, G.2    Rajan, N.3
  • 42
    • 34548544839 scopus 로고    scopus 로고
    • A novel mutation of CYLD in a Chinese family with multiple familial trichoepithelioma and no CYLD protein expression in the tumour tissue
    • Zuo Y-G, Xu Y, Wang B, et al. A novel mutation of CYLD in a Chinese family with multiple familial trichoepithelioma and no CYLD protein expression in the tumour tissue. Br J Dermatol 2007, 157:818-821.
    • (2007) Br J Dermatol , vol.157 , pp. 818-821
    • Zuo, Y.-G.1    Xu, Y.2    Wang, B.3
  • 43
    • 28344456279 scopus 로고    scopus 로고
    • A genomic and functional inventory of deubiquitinating enzymes
    • Nijman SMB, Luna-Vargas MPA, Velds A, et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 2005, 123:773-786.
    • (2005) Cell , vol.123 , pp. 773-786
    • Nijman, S.M.B.1    Luna-Vargas, M.P.A.2    Velds, A.3
  • 44
    • 44649101850 scopus 로고    scopus 로고
    • Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series
    • Ikeda F, Dikic I Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series. EMBO Rep 2008, 9:536-542.
    • (2008) EMBO Rep , vol.9 , pp. 536-542
    • Ikeda, F.1    Dikic, I.2
  • 45
    • 39549106692 scopus 로고    scopus 로고
    • The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
    • Komander D, Lord CJ, Scheel H, et al. The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Mol Cell 2008, 29:451-464.
    • (2008) Mol Cell , vol.29 , pp. 451-464
    • Komander, D.1    Lord, C.J.2    Scheel, H.3
  • 46
    • 34250368115 scopus 로고    scopus 로고
    • Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses
    • Reiley WW, Jin W, Lee AJ, et al. Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. J Exp Med 2007, 204:1475-1485.
    • (2007) J Exp Med , vol.204 , pp. 1475-1485
    • Reiley, W.W.1    Jin, W.2    Lee, A.J.3
  • 47
    • 77649259009 scopus 로고    scopus 로고
    • Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl
    • Tauriello DVF, Haegebarth A, Kuper I, et al. Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl. Mol Cell 2010, 37:607-619.
    • (2010) Mol Cell , vol.37 , pp. 607-619
    • Tauriello, D.V.F.1    Haegebarth, A.2    Kuper, I.3
  • 48
    • 84860284249 scopus 로고    scopus 로고
    • CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt
    • Lim JH, Jono H, Komatsu K, et al. CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt. Nat Commun 2012, 3:771.
    • (2012) Nat Commun , vol.3 , pp. 771
    • Lim, J.H.1    Jono, H.2    Komatsu, K.3
  • 49
    • 84919969091 scopus 로고    scopus 로고
    • The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate Notch signalling
    • Rajan N, Elliott RJR, Smith A, et al. The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate Notch signalling. Oncotarget 2014, 5:12126-12140.
    • (2014) Oncotarget , vol.5 , pp. 12126-12140
    • Rajan, N.1    Elliott, R.J.R.2    Smith, A.3
  • 50
    • 65649114699 scopus 로고    scopus 로고
    • Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation
    • Hutti JE, Shen RR, Abbott DW, et al. Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Mol Cell 2009, 34:461-472.
    • (2009) Mol Cell , vol.34 , pp. 461-472
    • Hutti, J.E.1    Shen, R.R.2    Abbott, D.W.3
  • 51
    • 33750598021 scopus 로고    scopus 로고
    • Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
    • Zhang J, Stirling B, Temmerman ST, et al. Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice. J Clin Invest 2006, 116:3042-3049.
    • (2006) J Clin Invest , vol.116 , pp. 3042-3049
    • Zhang, J.1    Stirling, B.2    Temmerman, S.T.3
  • 52
    • 65949122102 scopus 로고    scopus 로고
    • Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation
    • Trompouki E, Tsagaratou A, Kosmidis SK, et al. Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation. Neoplasia 2009, 11:469-476.
    • (2009) Neoplasia , vol.11 , pp. 469-476
    • Trompouki, E.1    Tsagaratou, A.2    Kosmidis, S.K.3
  • 53
    • 35748956767 scopus 로고    scopus 로고
    • Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD
    • Hövelmeyer N, Wunderlich FT, Massoumi R, et al. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med 2007, 204:2615-2627.
    • (2007) J Exp Med , vol.204 , pp. 2615-2627
    • Hövelmeyer, N.1    Wunderlich, F.T.2    Massoumi, R.3
  • 54
    • 84867572416 scopus 로고    scopus 로고
    • Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice
    • Urbanik T, Boger RJ, Longerich T, et al. Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice. J Hepatol 2012, 57:995-1003.
    • (2012) J Hepatol , vol.57 , pp. 995-1003
    • Urbanik, T.1    Boger, R.J.2    Longerich, T.3
  • 55
    • 67649672157 scopus 로고    scopus 로고
    • Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling
    • Blake PW, Toro JR Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling. Hum Mutat 2009, 30:1025-1036.
    • (2009) Hum Mutat , vol.30 , pp. 1025-1036
    • Blake, P.W.1    Toro, J.R.2
  • 56
    • 33645103440 scopus 로고    scopus 로고
    • Regulation of T cell development by the deubiquitinating enzyme CYLD
    • Reiley WW, Zhang M, Jin W, et al. Regulation of T cell development by the deubiquitinating enzyme CYLD. Nat Immunol 2006, 7:411-417.
    • (2006) Nat Immunol , vol.7 , pp. 411-417
    • Reiley, W.W.1    Zhang, M.2    Jin, W.3
  • 57
    • 35748956767 scopus 로고    scopus 로고
    • Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD
    • Hövelmeyer N, Wunderlich FT, Massoumi R, et al. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med 2007, 204:2615-2627.
    • (2007) J Exp Med , vol.204 , pp. 2615-2627
    • Hövelmeyer, N.1    Wunderlich, F.T.2    Massoumi, R.3
  • 58
    • 67651091771 scopus 로고    scopus 로고
    • Naturally occurring short splice variant of CYLD positively regulates dendritic cell function
    • Srokowski CC, Masri J, Hövelmeyer N, et al. Naturally occurring short splice variant of CYLD positively regulates dendritic cell function. Blood 2009, 113:5891-5895.
    • (2009) Blood , vol.113 , pp. 5891-5895
    • Srokowski, C.C.1    Masri, J.2    Hövelmeyer, N.3
  • 59
    • 0030018793 scopus 로고    scopus 로고
    • The gene for multiple familial trichoepithelioma maps to chromosome 9p21
    • Harada H, Hashimoto K, Ko Ms The gene for multiple familial trichoepithelioma maps to chromosome 9p21. J Invest Dermatol 1996, 107:41-43.
    • (1996) J Invest Dermatol , vol.107 , pp. 41-43
    • Harada, H.1    Hashimoto, K.2    Ko, M.3
  • 60
    • 84914175290 scopus 로고    scopus 로고
    • Large germline deletions of the CYLD gene in patients with Brooke-Spiegler syndrome and multiple familial trichoepithelioma
    • Vanecek T, Halbhuber Z, Kacerovska D, et al. Large germline deletions of the CYLD gene in patients with Brooke-Spiegler syndrome and multiple familial trichoepithelioma. Am J Dermatopathol 2014, 36:868-874.
    • (2014) Am J Dermatopathol , vol.36 , pp. 868-874
    • Vanecek, T.1    Halbhuber, Z.2    Kacerovska, D.3
  • 61
    • 70349739595 scopus 로고    scopus 로고
    • A case of Brooke-Spiegler syndrome with a novel germline deep intronic mutation in the CYLD gene leading to intronic exonization, diverse somatic mutations, and unusual histology
    • Kazakov DV, Thoma-Uszynski S, Vanecek T, Kacerovska D, Grossmann P, Michal M A case of Brooke-Spiegler syndrome with a novel germline deep intronic mutation in the CYLD gene leading to intronic exonization, diverse somatic mutations, and unusual histology. Am J Dermatopathol 2009, 31:664-673.
    • (2009) Am J Dermatopathol , vol.31 , pp. 664-673
    • Kazakov, D.V.1    Thoma-Uszynski, S.2    Vanecek, T.3    Kacerovska, D.4    Grossmann, P.5    Michal, M.6
  • 62
    • 84886439415 scopus 로고    scopus 로고
    • A mutational hotspot in CYLD causing cylindromas: a comparison of phenotypes arising in different genetic backgrounds
    • Nagy N, Rajan N, Farkas K, Kinyó A, Kemény L, Széll M A mutational hotspot in CYLD causing cylindromas: a comparison of phenotypes arising in different genetic backgrounds. Acta Derm Venereol 2013, 93:743-745.
    • (2013) Acta Derm Venereol , vol.93 , pp. 743-745
    • Nagy, N.1    Rajan, N.2    Farkas, K.3    Kinyó, A.4    Kemény, L.5    Széll, M.6
  • 63
    • 0019166875 scopus 로고
    • A grossly disfiguring case of epithelioma adenoides cysticum in an African
    • Jacyk WK, Isaac F A grossly disfiguring case of epithelioma adenoides cysticum in an African. Clin Exp Dermatol 1980, 5:421-423.
    • (1980) Clin Exp Dermatol , vol.5 , pp. 421-423
    • Jacyk, W.K.1    Isaac, F.2
  • 64
    • 3442883360 scopus 로고    scopus 로고
    • Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene
    • Salhi A, Bornholdt D, Oeffner F, et al. Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene. Cancer Res 2004, 64:5113-5117.
    • (2004) Cancer Res , vol.64 , pp. 5113-5117
    • Salhi, A.1    Bornholdt, D.2    Oeffner, F.3
  • 65
    • 80054044033 scopus 로고    scopus 로고
    • Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
    • Rajan N, Elliott R, Clewes O, et al. Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours. Oncogene 2011, 30:4243-4260.
    • (2011) Oncogene , vol.30 , pp. 4243-4260
    • Rajan, N.1    Elliott, R.2    Clewes, O.3
  • 66
    • 0035134022 scopus 로고    scopus 로고
    • Controls of hair follicle cycling
    • Stenn KS, Paus R Controls of hair follicle cycling. Physiol Rev 2001, 81:449-494.
    • (2001) Physiol Rev , vol.81 , pp. 449-494
    • Stenn, K.S.1    Paus, R.2
  • 67
    • 0037342938 scopus 로고    scopus 로고
    • High frequency and diversity of cutaneous appendageal tumors in organ transplant recipients
    • Harwood CA, McGregor JM, Swale VJ, et al. High frequency and diversity of cutaneous appendageal tumors in organ transplant recipients. J Am Acad Dermatol 2003, 48:401-408.
    • (2003) J Am Acad Dermatol , vol.48 , pp. 401-408
    • Harwood, C.A.1    McGregor, J.M.2    Swale, V.J.3
  • 68
    • 79958200205 scopus 로고    scopus 로고
    • The MYB-NFIB gene fusion-a novel genetic link between adenoid cystic carcinoma and dermal cylindroma
    • Fehr A, Kovács A, Löning T, Frierson H, van den Oord J, Stenman G The MYB-NFIB gene fusion-a novel genetic link between adenoid cystic carcinoma and dermal cylindroma. J Pathol 2011, 224:322-327.
    • (2011) J Pathol , vol.224 , pp. 322-327
    • Fehr, A.1    Kovács, A.2    Löning, T.3    Frierson, H.4    van den Oord, J.5    Stenman, G.6
  • 69
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • Persson M, Andrén Y, Mark J, Horlings HM, Persson F, Stenman G Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci USA 2009, 106:18740-18744.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18740-18744
    • Persson, M.1    Andrén, Y.2    Mark, J.3    Horlings, H.M.4    Persson, F.5    Stenman, G.6
  • 70
    • 84881474156 scopus 로고    scopus 로고
    • TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior
    • Ivanov SV, Panaccione A, Brown B, et al. TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. Oncogene 2013, 32:3698-3710.
    • (2013) Oncogene , vol.32 , pp. 3698-3710
    • Ivanov, S.V.1    Panaccione, A.2    Brown, B.3
  • 71
    • 84879627051 scopus 로고    scopus 로고
    • Whole exome sequencing of adenoid cystic carcinoma
    • Stephens PJ, Davies HR, Mitani Y, et al. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest 2013, 123:2965-2968.
    • (2013) J Clin Invest , vol.123 , pp. 2965-2968
    • Stephens, P.J.1    Davies, H.R.2    Mitani, Y.3
  • 72
    • 84946040120 scopus 로고    scopus 로고
    • COSMIC: exploring the world's knowledge of somatic mutations in human cancer
    • Forbes SA, Beare D, Gunasekaran P, et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res 2015, 43:D805-D811.
    • (2015) Nucleic Acids Res , vol.43 , pp. D805-D811
    • Forbes, S.A.1    Beare, D.2    Gunasekaran, P.3
  • 73
    • 84933525942 scopus 로고    scopus 로고
    • Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells
    • Kobayashi T, Masoumi KC, Massoumi R Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene 2015, 34:2251-2260.
    • (2015) Oncogene , vol.34 , pp. 2251-2260
    • Kobayashi, T.1    Masoumi, K.C.2    Massoumi, R.3
  • 74
    • 84893089028 scopus 로고    scopus 로고
    • CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma
    • Pannem RR, Dorn C, Ahlqvist K, Bosserhoff AK, Hellerbrand C, Massoumi R CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma. Carcinogenesis 2014, 35:461-468.
    • (2014) Carcinogenesis , vol.35 , pp. 461-468
    • Pannem, R.R.1    Dorn, C.2    Ahlqvist, K.3    Bosserhoff, A.K.4    Hellerbrand, C.5    Massoumi, R.6
  • 75
    • 65349181387 scopus 로고    scopus 로고
    • Familial cylindromatosis and brooke-spiegler syndrome: a review of current therapeutic approaches and the surgical challenges posed by two affected families
    • Rajan N, Trainer AH, Burn J, Langtry JA Familial cylindromatosis and brooke-spiegler syndrome: a review of current therapeutic approaches and the surgical challenges posed by two affected families. Dermatol Surg 2009, 35:845-852.
    • (2009) Dermatol Surg , vol.35 , pp. 845-852
    • Rajan, N.1    Trainer, A.H.2    Burn, J.3    Langtry, J.A.4
  • 76
    • 84887242639 scopus 로고    scopus 로고
    • Infiltrative recurrent eccrine spiradenoma of the anterior neck treated using Mohs micrographic surgery
    • Rahim RR, Rajan N, Langtry JA Infiltrative recurrent eccrine spiradenoma of the anterior neck treated using Mohs micrographic surgery. Dermatol Surg 2013, 39:1711-1714.
    • (2013) Dermatol Surg , vol.39 , pp. 1711-1714
    • Rahim, R.R.1    Rajan, N.2    Langtry, J.A.3
  • 77
    • 33745025242 scopus 로고    scopus 로고
    • An evaluation of the efficacy of topical application of salicyclic acid for the treatment of familial cylindromatosis
    • Oosterkamp HM, Neering H, Nijman SMB, et al. An evaluation of the efficacy of topical application of salicyclic acid for the treatment of familial cylindromatosis. Br J Dermatol 2006, 155:182-185.
    • (2006) Br J Dermatol , vol.155 , pp. 182-185
    • Oosterkamp, H.M.1    Neering, H.2    Nijman, S.M.B.3
  • 78
    • 3142515724 scopus 로고
    • Cylindromatosis simulating neurofibromatosis
    • Baden HP Cylindromatosis simulating neurofibromatosis. N Engl J Med 1962, 267:296-297.
    • (1962) N Engl J Med , vol.267 , pp. 296-297
    • Baden, H.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.