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Volumn 47, Issue 9, 2015, Pages 1703-1713

Homoarginine in the renal and cardiovascular systems

Author keywords

AGAT; Cardiovascular; Heart failure; Homoarginine; Mortality; Nitric oxide; Stroke

Indexed keywords

ARGININE; GLYCINE AMIDINOTRANSFERASE; HOMOARGININE; NITRIC OXIDE; AMIDINOTRANSFERASE; BIOLOGICAL MARKER; GLYCINE; GUANIDINOACETIC ACID;

EID: 84940461365     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-1993-2     Document Type: Article
Times cited : (70)

References (77)
  • 1
    • 0035652291 scopus 로고    scopus 로고
    • Long-term effect of partial nephrectomy on biochemical parameters, kidney histology, and guanidine compound levels in mice
    • Al Banachaabouchi M, Marescau B, Van Marck E, D'hooge R, Deyn PP (2001) Long-term effect of partial nephrectomy on biochemical parameters, kidney histology, and guanidine compound levels in mice. Metabolism 50:1418-1425
    • (2001) Metabolism , vol.50 , pp. 1418-1425
    • Al Banachaabouchi, M.1    Marescau, B.2    Van Marck, E.3    D'hooge, R.4    Deyn, P.P.5
  • 4
    • 84910136958 scopus 로고    scopus 로고
    • Serum reference intervals of homoarginine, ADMA, and SDMA in the Study of Health in Pomerania
    • 1:CAS:528:DC%2BC2cXhvFamurrJ 24945429
    • Atzler D, Schwedhelm E, Nauck M, Ittermann T, Boger RH, Friedrich N (2014b) Serum reference intervals of homoarginine, ADMA, and SDMA in the Study of Health in Pomerania. Clin Chem Lab Med 52:1835-1842
    • (2014) Clin Chem Lab Med , vol.52 , pp. 1835-1842
    • Atzler, D.1    Schwedhelm, E.2    Nauck, M.3    Ittermann, T.4    Boger, R.H.5    Friedrich, N.6
  • 6
    • 0038097265 scopus 로고
    • The isolation of L-homoarginine from seeds of Lathyrus cicero
    • 1243914 1:CAS:528:DyaF3sXjsVOksw%3D%3D 13970459
    • Bell EA (1962) The isolation of L-homoarginine from seeds of Lathyrus cicero. Biochem J 85:91-93
    • (1962) Biochem J , vol.85 , pp. 91-93
    • Bell, E.A.1
  • 7
    • 84940446761 scopus 로고    scopus 로고
    • Possible sources and functions of L-homoarginine in the brain: review of the literature and own findings
    • 2015 Mar 20 (Epub ahead of print)
    • Bernstein HG, Jäger K, Dobrowolny H, Steiner J, Keilhoff G, Bogerts B, Laube G (2015) Possible sources and functions of L-homoarginine in the brain: review of the literature and own findings. Amino Acids. 2015 Mar 20 (Epub ahead of print)
    • (2015) Amino Acids
    • Bernstein, H.G.1    Jäger, K.2    Dobrowolny, H.3    Steiner, J.4    Keilhoff, G.5    Bogerts, B.6    Laube, G.7
  • 8
    • 0024520427 scopus 로고
    • Stimulus-secretion coupling of arginine-induced insulin release. uptake of metabolized and nonmetabolized cationic amino acids by pancreatic islets
    • 1:CAS:528:DyaL1MXmvFOnsQ%3D%3D 2462484
    • Blachier F, Mourtada A, Sener A, Malaisse WJ (1989) Stimulus-secretion coupling of arginine-induced insulin release. uptake of metabolized and nonmetabolized cationic amino acids by pancreatic islets. Endocrinology 124:134-141
    • (1989) Endocrinology , vol.124 , pp. 134-141
    • Blachier, F.1    Mourtada, A.2    Sener, A.3    Malaisse, W.J.4
  • 9
    • 77951768942 scopus 로고    scopus 로고
    • Genetic loci influencing kidney function and chronic kidney disease
    • 3748585 1:CAS:528:DC%2BC3cXksFakurk%3D 20383145
    • Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS et al (2010) Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 42:373-375
    • (2010) Nat Genet , vol.42 , pp. 373-375
    • Chambers, J.C.1    Zhang, W.2    Lord, G.M.3    Van Der Harst, P.4    Lawlor, D.A.5    Sehmi, J.S.6
  • 10
    • 0027368884 scopus 로고
    • Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats
    • 1:CAS:528:DyaK2cXnsVGlug%3D%3D 7503951
    • Chen PY, Sanders PW (1993) Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats. Hypertension 22:812-818
    • (1993) Hypertension , vol.22 , pp. 812-818
    • Chen, P.Y.1    Sanders, P.W.2
  • 13
    • 33747163976 scopus 로고    scopus 로고
    • Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis
    • 16820567
    • Cullen ME, Yuen AH, Felkin LE, Smolenski RT, Hall JL, Grindle S, Miller LW, Birks EJ, Yacoub MH, Barton PJ (2006) Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis. Circulation 114(1 Suppl):I16-I20
    • (2006) Circulation , vol.114 , Issue.1 , pp. I16-I20
    • Cullen, M.E.1    Yuen, A.H.2    Felkin, L.E.3    Smolenski, R.T.4    Hall, J.L.5    Grindle, S.6    Miller, L.W.7    Birks, E.J.8    Yacoub, M.H.9    Barton, P.J.10
  • 14
    • 84867579062 scopus 로고    scopus 로고
    • Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine
    • 1:CAS:528:DC%2BC38XhtlCjt7bF 23010440
    • Davids M, Ndika JD, Salomons GS, Blom HJ, Teerlink T (2012) Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine. FEBS Lett 586:3653-3657
    • (2012) FEBS Lett , vol.586 , pp. 3653-3657
    • Davids, M.1    Ndika, J.D.2    Salomons, G.S.3    Blom, H.J.4    Teerlink, T.5
  • 19
    • 77957308438 scopus 로고    scopus 로고
    • l-arginine:glycine amidinotransferase (AGAT) deficiency: clinical presentation and response to treatment in two patients with a novel mutation
    • 1:CAS:528:DC%2BC3cXht1Cmtb%2FF 20682460
    • Edvardson S, Korman SH, Livne A, Shaag A, Saada A, Nalbandian R, Allouche-Arnon H, Gomori JM, Katz-Brull R (2010) l-arginine:glycine amidinotransferase (AGAT) deficiency: clinical presentation and response to treatment in two patients with a novel mutation. Mol Genet Metab 101:228-232
    • (2010) Mol Genet Metab , vol.101 , pp. 228-232
    • Edvardson, S.1    Korman, S.H.2    Livne, A.3    Shaag, A.4    Saada, A.5    Nalbandian, R.6    Allouche-Arnon, H.7    Gomori, J.M.8    Katz-Brull, R.9
  • 20
    • 84922393174 scopus 로고    scopus 로고
    • Endothelial dysfunction and brachial intima-media thickness: long term cardiovascular risk with claudication related to peripheral arterial disease: a prospective analysis
    • 10.1371/journal.pone.0093357 3989175 24740106
    • Hafner F, Kieninger A, Meinitzer A, Gary T, Froehlich H, Haas E, Hackl G, Eller P, Brodmann M, Seinost G (2014) Endothelial dysfunction and brachial intima-media thickness: long term cardiovascular risk with claudication related to peripheral arterial disease: a prospective analysis. PLoS ONE 9:e93357. doi: 10.1371/journal.pone.0093357
    • (2014) PLoS ONE , vol.9
    • Hafner, F.1    Kieninger, A.2    Meinitzer, A.3    Gary, T.4    Froehlich, H.5    Haas, E.6    Hackl, G.7    Eller, P.8    Brodmann, M.9    Seinost, G.10
  • 22
    • 0031713399 scopus 로고    scopus 로고
    • Arginine induced insulin release is decreased and glucagon increased in parallel with islet NO production
    • 1:CAS:528:DyaK1cXmtFSqtL0%3D 9725818
    • Henningsson R, Lundquist I (1998) Arginine induced insulin release is decreased and glucagon increased in parallel with islet NO production. Am J Physiol 275:E500-E506
    • (1998) Am J Physiol , vol.275 , pp. E500-E506
    • Henningsson, R.1    Lundquist, I.2
  • 24
    • 0142143846 scopus 로고
    • The effect of methyltestosterone on the rate of synthesis of creatine
    • 1:CAS:528:DyaH1cXjs12isQ%3D%3D 18902376
    • Hoberman HD, Sims EA, Engstrom WW (1948) The effect of methyltestosterone on the rate of synthesis of creatine. J Biol Chem 173:111-116
    • (1948) J Biol Chem , vol.173 , pp. 111-116
    • Hoberman, H.D.1    Sims, E.A.2    Engstrom, W.W.3
  • 26
    • 8844234900 scopus 로고    scopus 로고
    • l-Arginine uptake affects nitric oxide production and blood flow in the renal medulla
    • 1:CAS:528:DC%2BD2cXhtVOmu7rM 15319219
    • Kakoki M, Kim HS, Arendshorst WJ, Mattson DL (2004) l-Arginine uptake affects nitric oxide production and blood flow in the renal medulla. Am J Physiol Regul Integr Comp Physiol 287:R1478-R1485
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287 , pp. R1478-R1485
    • Kakoki, M.1    Kim, H.S.2    Arendshorst, W.J.3    Mattson, D.L.4
  • 28
    • 84940446635 scopus 로고    scopus 로고
    • Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease
    • 2015 Jan 25 (Epub ahead of print)
    • Kayacelebi AA, Willers J, Pham VV, Hahn A, Schneider JY, Rothmann S, Frölich JC, Tsikas D (2015) Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease. Amino Acids 2015 Jan 25 (Epub ahead of print)
    • (2015) Amino Acids
    • Kayacelebi, A.A.1    Willers, J.2    Pham, V.V.3    Hahn, A.4    Schneider, J.Y.5    Rothmann, S.6    Frölich, J.C.7    Tsikas, D.8
  • 29
    • 84870821096 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks gestation and preeclampsia: a case-control study
    • 1:CAS:528:DC%2BC38XhvVSmt7%2FL 22158463
    • Khalil AA, Tsikas D, Akolekar R, Jordan J, Nicolaides KH (2013) Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks gestation and preeclampsia: a case-control study. J Hum Hypertens 27:38-43
    • (2013) J Hum Hypertens , vol.27 , pp. 38-43
    • Khalil, A.A.1    Tsikas, D.2    Akolekar, R.3    Jordan, J.4    Nicolaides, K.H.5
  • 30
    • 34247101940 scopus 로고    scopus 로고
    • The past, presence and future of ADMA in nephrology
    • 1:CAS:528:DC%2BD2sXmslClu7k%3D 17452300
    • Kielstein J, Flieser D (2007) The past, presence and future of ADMA in nephrology. Nephrol Ther 3:47-54
    • (2007) Nephrol Ther , vol.3 , pp. 47-54
    • Kielstein, J.1    Flieser, D.2
  • 32
    • 67349175651 scopus 로고    scopus 로고
    • Multiple loci associated with indices of renal function and chronic kidney disease
    • 3039280 19430482
    • Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M et al (2009) Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 41:712-717
    • (2009) Nat Genet , vol.41 , pp. 712-717
    • Köttgen, A.1    Glazer, N.L.2    Dehghan, A.3    Hwang, S.J.4    Katz, R.5    Li, M.6
  • 34
    • 0028948369 scopus 로고
    • Guanidino compound metabolism in rats subjected to 20% to 90% nephrectomy
    • 1:CAS:528:DyaK2MXkvVWgs7o%3D 7536856
    • Levillain O, Marescau B, de Deyn PP (1995) Guanidino compound metabolism in rats subjected to 20% to 90% nephrectomy. Kidney Int 47:464-472
    • (1995) Kidney Int , vol.47 , pp. 464-472
    • Levillain, O.1    Marescau, B.2    De Deyn, P.P.3
  • 37
    • 0003238947 scopus 로고    scopus 로고
    • Differences in sialic acid residues among bone alkaline phosphatase isoforms: a physical, biochemical, and immunological characterization
    • 1:CAS:528:DC%2BD3sXjt1amsw%3D%3D 12232676
    • Magnusson P, Farley P (2002) Differences in sialic acid residues among bone alkaline phosphatase isoforms: a physical, biochemical, and immunological characterization. Calcif Tissue Int 71:508-518
    • (2002) Calcif Tissue Int , vol.71 , pp. 508-518
    • Magnusson, P.1    Farley, P.2
  • 38
    • 0026723952 scopus 로고
    • Guanidino compounds in serum, urine, liver, kidney, and brain of man and some ureotelic animals
    • 1:CAS:528:DyaK38XhslSrtrs%3D 1588833
    • Marescau B, Deshmukh DR, Kockx M, Possemiers I, Qureshi IA, Wiechert P, De Deyn PP (1992) Guanidino compounds in serum, urine, liver, kidney, and brain of man and some ureotelic animals. Metabolism 41:526-532
    • (1992) Metabolism , vol.41 , pp. 526-532
    • Marescau, B.1    Deshmukh, D.R.2    Kockx, M.3    Possemiers, I.4    Qureshi, I.A.5    Wiechert, P.6    De Deyn, P.P.7
  • 41
  • 42
    • 34447132227 scopus 로고    scopus 로고
    • Upregulation of the creatine synthetic pathway in skeletal muscles of mature mdx mice
    • 2706264 17588756
    • McClure WC, Rabon RE, Ogawa H, Tseng BS (2007) Upregulation of the creatine synthetic pathway in skeletal muscles of mature mdx mice. Neuromuscul Disord 17:639-650
    • (2007) Neuromuscul Disord , vol.17 , pp. 639-650
    • McClure, W.C.1    Rabon, R.E.2    Ogawa, H.3    Tseng, B.S.4
  • 43
    • 0019320718 scopus 로고
    • The effect of growth hormone and thyroxine on the amount of l-arginine:glycine amidinotransferase in kidneys of hypophysectomized rats. Purification and some properties of rat kidney transamidinase
    • 1:CAS:528:DyaL3cXht1eqsLg%3D 6766137
    • McGuire DM, Tormanen CD, Segal IS, Van Pilsum JF (1980) The effect of growth hormone and thyroxine on the amount of l-arginine:glycine amidinotransferase in kidneys of hypophysectomized rats. Purification and some properties of rat kidney transamidinase. J Biol Chem 255:1152-1159
    • (1980) J Biol Chem , vol.255 , pp. 1152-1159
    • McGuire, D.M.1    Tormanen, C.D.2    Segal, I.S.3    Van Pilsum, J.F.4
  • 45
    • 78650993607 scopus 로고    scopus 로고
    • Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study
    • 1:CAS:528:DC%2BC3MXitFSksrw%3D 21036946
    • Meinitzer A, Kielstein JT, Pilz S, Drechsler C, Ritz E, Boehm BO, Winkelmann BR, März W (2011b) Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study. Clin Chem 57:112-121
    • (2011) Clin Chem , vol.57 , pp. 112-121
    • Meinitzer, A.1    Kielstein, J.T.2    Pilz, S.3    Drechsler, C.4    Ritz, E.5    Boehm, B.O.6    Winkelmann, B.R.7    März, W.8
  • 46
    • 0032555182 scopus 로고    scopus 로고
    • Substrate specificity of NO synthases: detailed comparison of l-arginine, homo-l-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-l-arginine
    • 1:CAS:528:DyaK1cXktFKqtLg%3D 9671515
    • Moali C, Boucher JL, Sari MA, Stuehr DJ, Mansuy D (1998) Substrate specificity of NO synthases: detailed comparison of l-arginine, homo-l-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-l-arginine. Biochemistry 37:10453-10460
    • (1998) Biochemistry , vol.37 , pp. 10453-10460
    • Moali, C.1    Boucher, J.L.2    Sari, M.A.3    Stuehr, D.J.4    Mansuy, D.5
  • 47
    • 84860170497 scopus 로고    scopus 로고
    • Developmental progress and creatine restoration upon long-term creatine supplementation of a patient with arginine:glycine amidinotransferase deficiency
    • 1:CAS:528:DC%2BC38Xjt1Gksr4%3D 22386973
    • Ndika JD, Johnston K, Barkovich JA, Wirt MD, O'Neill P, Betsalel OT, Jakobs C, Salomons GS (2012) Developmental progress and creatine restoration upon long-term creatine supplementation of a patient with arginine:glycine amidinotransferase deficiency. Mol Genet Metab 106:48-54
    • (2012) Mol Genet Metab , vol.106 , pp. 48-54
    • Ndika, J.D.1    Johnston, K.2    Barkovich, J.A.3    Wirt, M.D.4    O'Neill, P.5    Betsalel, O.T.6    Jakobs, C.7    Salomons, G.S.8
  • 49
    • 79954637472 scopus 로고    scopus 로고
    • Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiography
    • 1:CAS:528:DC%2BC3MXjvVOjsLo%3D 21311067
    • Pilz S, Tomaschitz A, Meinitzer A, Drechsler C, Ritz E, Krane V, Wanner C, Bohm BO, März W (2011a) Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiography. Stroke 42:1132-1134
    • (2011) Stroke , vol.42 , pp. 1132-1134
    • Pilz, S.1    Tomaschitz, A.2    Meinitzer, A.3    Drechsler, C.4    Ritz, E.5    Krane, V.6    Wanner, C.7    Bohm, B.O.8    März, W.9
  • 55
    • 0025366847 scopus 로고
    • An L-arginine/nitric oxide pathway present in human platelets regulates aggregation
    • 54288 1:CAS:528:DyaK3cXkslGmt7k%3D 1695013
    • Radomski MW, Palmer RM, Moncada S (1990) An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci U S A 87:5193-5197
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5193-5197
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 56
    • 0037759735 scopus 로고
    • The isolation and characterization of l-homoarginine from seeds of Lathyrus sativus
    • 1:CAS:528:DyaF3sXlsVChsw%3D%3D 13973060
    • Rao SL, Ramachandran LK, Adiga PR (1963) The isolation and characterization of l-homoarginine from seeds of Lathyrus sativus. Biochemistry 2:298-300
    • (1963) Biochemistry , vol.2 , pp. 298-300
    • Rao, S.L.1    Ramachandran, L.K.2    Adiga, P.R.3
  • 58
    • 77949313676 scopus 로고    scopus 로고
    • Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production
    • 2820767 1:CAS:528:DC%2BC3cXhvFCrt7Y%3D 20018850
    • Rodionov RN, Murry DJ, Vaulman SF, Stevens JW, Lentz SR (2010) Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production. J Biol Chem 285:5385-5391
    • (2010) J Biol Chem , vol.285 , pp. 5385-5391
    • Rodionov, R.N.1    Murry, D.J.2    Vaulman, S.F.3    Stevens, J.W.4    Lentz, S.R.5
  • 59
    • 0343811639 scopus 로고
    • Homocitrulline and homoarginine synthesis from lysine
    • 1:CAS:528:DyaF2cXkt1Ont7s%3D 14148430
    • Ryan WL, Well IC (1964) Homocitrulline and homoarginine synthesis from lysine. Science 144:1122-1127
    • (1964) Science , vol.144 , pp. 1122-1127
    • Ryan, W.L.1    Well, I.C.2
  • 60
    • 0016588896 scopus 로고
    • Effects of arginine homologous and other guanidino compounds on the ATP level and glucose oxidation in isolated fat cells
    • 1:CAS:528:DyaE2MXkvFWlsbc%3D 1181275
    • Schwegler F, Stock W (1975) Effects of arginine homologous and other guanidino compounds on the ATP level and glucose oxidation in isolated fat cells. Hoppe Seylers Z Physiol Chem 356:839-844
    • (1975) Hoppe Seylers Z Physiol Chem , vol.356 , pp. 839-844
    • Schwegler, F.1    Stock, W.2
  • 62
    • 84881080762 scopus 로고    scopus 로고
    • Lessons from neurolathyrism: a disease of the past & the future of Lathyrus sativus (Khesari dal)
    • 3767245 24056554
    • Singh SS, Rao SL (2013) Lessons from neurolathyrism: a disease of the past & the future of Lathyrus sativus (Khesari dal). Indian J Med Res 138:32-37
    • (2013) Indian J Med Res , vol.138 , pp. 32-37
    • Singh, S.S.1    Rao, S.L.2
  • 63
    • 84899623176 scopus 로고    scopus 로고
    • Tobacco smoking decreases plasma concentration of the emerging cardiovascular risk marker, L-homoarginine
    • 1:CAS:528:DC%2BC2cXhtVagsrnF 24583919
    • Sobczak A, Prokopowicz A, Radek M, Szula M, Zaciera M, Kurek J, Goniewicz ML (2014) Tobacco smoking decreases plasma concentration of the emerging cardiovascular risk marker, L-homoarginine. Circ J 78:1254-1258
    • (2014) Circ J , vol.78 , pp. 1254-1258
    • Sobczak, A.1    Prokopowicz, A.2    Radek, M.3    Szula, M.4    Zaciera, M.5    Kurek, J.6    Goniewicz, M.L.7
  • 64
    • 84940458240 scopus 로고
    • Über d, l-α-Methylarginin
    • 1:CAS:528:DyaB28XivF2ksQ%3D%3D
    • Steib H (1926) Über d, l-α-Methylarginin. Hoppe Seylers Z Physiol Chem 155:279-291
    • (1926) Hoppe Seylers Z Physiol Chem , vol.155 , pp. 279-291
    • Steib, H.1
  • 65
    • 0038436220 scopus 로고
    • New synthesis of α-amino-ε-guanidino-n-caprionic acid (homoarginine) and its possible conversion in vivo into lysine
    • 1:CAS:528:DyaG3cXivF2nsw%3D%3D
    • Stevens CM, Bush JA (1950) New synthesis of α-amino-ε-guanidino-n-caprionic acid (homoarginine) and its possible conversion in vivo into lysine. J Biol Chem 183:139-147
    • (1950) J Biol Chem , vol.183 , pp. 139-147
    • Stevens, C.M.1    Bush, J.A.2
  • 67
    • 0021930853 scopus 로고
    • Impaired metabolism of guanidinoacetic acid in uremia
    • 1:STN:280:DyaL28%2FhsVKgug%3D%3D 4047275
    • Tofuku Y, Muramoto H, Kuroda M, Takeda R (1985) Impaired metabolism of guanidinoacetic acid in uremia. Nephron 41:174-178
    • (1985) Nephron , vol.41 , pp. 174-178
    • Tofuku, Y.1    Muramoto, H.2    Kuroda, M.3    Takeda, R.4
  • 70
    • 84904994046 scopus 로고    scopus 로고
    • Do Homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system?
    • 24931514
    • Tsikas D, Kayacelebi AA (2014) Do Homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system? Circ J 78:2094-2095
    • (2014) Circ J , vol.78 , pp. 2094-2095
    • Tsikas, D.1    Kayacelebi, A.A.2
  • 71
    • 0342757751 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthase inhibitors are responsible for the l-arginine paradox
    • 1:CAS:528:DC%2BD3cXltVGrsL0%3D 10922458
    • Tsikas D, Böger RH, Sandmann J, Bode-Böger SM, Fröhlich JC (2000) Endogenous nitric oxide synthase inhibitors are responsible for the l-arginine paradox. FEBS Lett 478:1-3
    • (2000) FEBS Lett , vol.478 , pp. 1-3
    • Tsikas, D.1    Böger, R.H.2    Sandmann, J.3    Bode-Böger, S.M.4    Fröhlich, J.C.5
  • 73
    • 84877579295 scopus 로고    scopus 로고
    • L-Homoarginine and l-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study
    • 23552121
    • van der Zwan LP, Davids M, Scheffer PG, Dekker JM, Stehouwer CD, Teerlink T (2013) L-Homoarginine and l-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study. J Hypertens 31:1114-1123
    • (2013) J Hypertens , vol.31 , pp. 1114-1123
    • Van Der Zwan, L.P.1    Davids, M.2    Scheffer, P.G.3    Dekker, J.M.4    Stehouwer, C.D.5    Teerlink, T.6
  • 75
    • 0033946125 scopus 로고    scopus 로고
    • Characterization of l-arginine transporters in rat renal inner medullary collecting duct
    • 1:CAS:528:DC%2BD3cXks1ymsbc%3D 10848517
    • Wu F, Cholewa B, Mattson DL (2000) Characterization of l-arginine transporters in rat renal inner medullary collecting duct. Am J Physiol Regul Integr Comp Physiol 278:R1506-R1512
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.278 , pp. R1506-R1512
    • Wu, F.1    Cholewa, B.2    Mattson, D.L.3
  • 77
    • 0035351264 scopus 로고    scopus 로고
    • Estrogen modulates the expression of l-arginine:glycine amidinotransferase in chick liver
    • 1:CAS:528:DC%2BD3MXlvFelsL0%3D 11506177
    • Zhu Y, Evans MI (2001) Estrogen modulates the expression of l-arginine:glycine amidinotransferase in chick liver. Mol Cell Biochem 221:139-145
    • (2001) Mol Cell Biochem , vol.221 , pp. 139-145
    • Zhu, Y.1    Evans, M.I.2


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