Do homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system?

Circulation Journal

Volumn 78, Issue 8, 2014, Pages 2094-2095

  Tsikas, Dimitrios ^a   Kayacelebi, Arslan Arinc ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84904994046     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-14-0484     Document Type: Letter

References (10)

1. Sobczak A, Prokopowicz A, Radek M, Szula M, Zaciera M, Kurek J, et al. Tobacco smoking decreases plasma concentration of the emerging cardiovascular risk marker, L-homoarginine. Circ J 2014; 78: 1254-1258.
2. März W, Meinitzer A, Drechsler C, Pilz S, Krane V, Kleber ME, et al. Homoarginine, cardiovascular risk, and mortality. Circulation 2010; 122: 967-975.
3. Valtonen P, Laitinen T, Lyyra-Laitinen T, Raitakari OT, Juonala M, Viikari JS, et al. Serum L-homoarginine concentration is elevated during normal pregnancy and is related to flow-mediated vasodilatation. Circ J 2008; 72: 1879-1884.
4. Pilz S, Meinitzer A, Tomaschitz A, Drechsler C, Ritz E, Krane V, et al. Low homoarginine concentration is a novel risk factor for heart disease. Heart 2011; 97: 1222-1227.
5. Khalil AA, Tsikas D, Akolekar R, Jordan J, Nicolaides KH. Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: A case-control study. J Hum Hypertens 2013; 27: 38-43.
6. Tomaschitz A, Meinitzer A, Pilz S, Rus-Machan J, Genser B, Drechsler C, et al. Homoarginine, kidney function and cardiovascular mortality risk. Nephrol Dial Transplant 2014; 29: 663-671.
7. van der Zwan LP, Davids M, Scheffer PG, Dekker JM, Stehouwer CD, Teerlink T. L-Homoarginine and L-arginine are antagonistically related to blood pressure in an elderly population: The Hoorn study. J Hypertens 2013; 31: 1114-1123.
8. Pilz S, Teerlink T, Scheffer PG, Meinitzer A, Rutters F, Tomaschitz A, et al. Homoarginine and mortality in an older population: The Hoorn study. Eur J Clin Invest 2014; 44: 200-208.
9. Kayacelebi AA, Nguyen TH, Neil C, Horowitz JD, Jordan J, Tsikas D. Homoarginine and 3-nitrotyrosine in patients with takotsubo cardiomyopathy. Int J Cardiol 2014; 173: 546-547.
10. Tsikas D, Schubert B, Gutzki FM, Sandmann J, Frölich JC. Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in humans by gas chromatography-tandem mass spectrometry as methyl ester tri (N-pentafluoropropionyl) derivative. J Chromatogr B 2003; 798: 87-99.