메뉴 건너뛰기




Volumn 78, Issue 3-4, 2010, Pages 181-188

NF-κB and Bcl-3 activation are prognostic in metastatic colorectal cancer

Author keywords

Colorectal carcinoma; NF B; P50; P65

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 3; PROTEIN P50; PROTEIN P52; SYNAPTOTAGMIN I; ONCOPROTEIN; PROTO ONCOGENE PROTEIN BCL 3; PROTO-ONCOGENE PROTEIN BCL-3; TRANSCRIPTION FACTOR;

EID: 77951035570     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000313697     Document Type: Article
Times cited : (74)

References (21)
  • 1
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factorkappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression
    • Basseres DS, Baldwin AS: Nuclear factorkappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene 2006; 25: 6817-6830.
    • (2006) Oncogene , vol.25 , pp. 6817-6830
    • Basseres, D.S.1    Baldwin, A.S.2
  • 2
    • 0027184023 scopus 로고
    • The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers
    • Fujita T, Nolan GP, Liou HC, Scott ML, Baltimore D: The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. Genes Dev 1993; 7(7B):1354-1363.
    • (1993) Genes Dev , vol.7 , Issue.7 B , pp. 1354-1363
    • Fujita, T.1    Nolan, G.P.2    Liou, H.C.3    Scott, M.L.4    Baltimore, D.5
  • 3
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • Baldwin AS: Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 2001; 107: 241-246.
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 5
    • 0035868342 scopus 로고    scopus 로고
    • Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/ Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
    • Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE: Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/ Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001; 20: 1287-1299.
    • (2001) Oncogene , vol.20 , pp. 1287-1299
    • Pianetti, S.1    Arsura, M.2    Romieu-Mourez, R.3    Coffey, R.J.4    Sonenshein, G.E.5
  • 6
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumor necrosis factor requires the Akt serine-threonine kinase
    • Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB: NF-kappaB activation by tumor necrosis factor requires the Akt serine-threonine kinase. Nature 1999; 401: 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 7
    • 0034961050 scopus 로고    scopus 로고
    • Roles of Akt/ PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/ c-myc transgenic mice
    • Factor V, Oliver AL, Panta GR, Thorgeirsson SS, Sonenshein GE, Arsura M: Roles of Akt/ PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/ c-myc transgenic mice. Hepatology 2001; 34: 32-41.
    • (2001) Hepatology , vol.34 , pp. 32-41
    • Factor, V.1    Oliver, A.L.2    Panta, G.R.3    Thorgeirsson, S.S.4    Sonenshein, G.E.5    Arsura, M.6
  • 8
    • 0030882666 scopus 로고    scopus 로고
    • Oncogenic Ha-Rasinduced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation
    • Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ, Baldwin AS Jr: Oncogenic Ha-Rasinduced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. J Biol Chem 1997; 272: 24113-24116.
    • (1997) J Biol Chem , vol.272 , pp. 24113-24116
    • Finco, T.S.1    Westwick, J.K.2    Norris, J.L.3    Beg, A.A.4    Der, C.J.5    Baldwin Jr., A.S.6
  • 9
    • 33644853585 scopus 로고    scopus 로고
    • Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
    • Izzo JG, Malhotra U, Wu TT, Ensor J, Luthra R, Lee JH, et al: Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. J Clin Oncol 2006; 24: 748-754.
    • (2006) J Clin Oncol , vol.24 , pp. 748-754
    • Izzo, J.G.1    Malhotra, U.2    Wu, T.T.3    Ensor, J.4    Luthra, R.5    Lee, J.H.6
  • 10
    • 34548536941 scopus 로고    scopus 로고
    • Nuclear factor-κ B tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy
    • Scartozzi M, Bearzi I, Pierantoni C, Mandolesi A, Loupakis F, Zaniboni A, et al: Nuclear factor-κ B tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy. J Clin Oncol 2007; 25: 3930-3935.
    • (2007) J Clin Oncol , vol.25 , pp. 3930-3935
    • Scartozzi, M.1    Bearzi, I.2    Pierantoni, C.3    Mandolesi, A.4    Loupakis, F.5    Zaniboni, A.6
  • 11
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3
    • Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS Jr: Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene 2000; 19: 1123-1131.
    • (2000) Oncogene , vol.19 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3    Baldwin Jr., A.S.4
  • 12
    • 37049004740 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas
    • O'Neil BH, Buzkova P, Farrah H, Kashatus D, Sanoff H, Goldberg RM, et al: Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology 2007; 72: 97-104.
    • (2007) Oncology , vol.72 , pp. 97-104
    • O'Neil, B.H.1    Buzkova, P.2    Farrah, H.3    Kashatus, D.4    Sanoff, H.5    Goldberg, R.M.6
  • 13
    • 0027446955 scopus 로고
    • The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers
    • Bours V, Franzoso G, Azarenko V, Park S, Kanno T, Brown K, et al: The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers. Cell 1993; 72: 729-739.
    • (1993) Cell , vol.72 , pp. 729-739
    • Bours, V.1    Franzoso, G.2    Azarenko, V.3    Park, S.4    Kanno, T.5    Brown, K.6
  • 14
    • 0027472317 scopus 로고
    • The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are i kappa B molecules and control nuclear translocation of NF-kappa B
    • Naumann M, Wulczyn FG, Scheidereit C: The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B. EMBO J 1993; 12: 213-222.
    • (1993) EMBO J , vol.12 , pp. 213-222
    • Naumann, M.1    Wulczyn, F.G.2    Scheidereit, C.3
  • 15
    • 14644422665 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers
    • Zhou Y, Eppenberger-Castori S, Marx C, Yau C, Scott GK, Eppenberger U, et al: Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers. Int J Biochem Cell Biol 2005; 37: 1130-1134.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1130-1134
    • Zhou, Y.1    Eppenberger-Castori, S.2    Marx, C.3    Yau, C.4    Scott, G.K.5    Eppenberger, U.6
  • 16
    • 17844368327 scopus 로고    scopus 로고
    • The MAPK signaling pathways and colorectal cancer
    • Fang J, Richardson B: The MAPK signaling pathways and colorectal cancer. Lancet Oncol 2005; 6: 322-337.
    • (2005) Lancet Oncol , vol.6 , pp. 322-337
    • Fang, J.1    Richardson, B.2
  • 17
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling
    • Romashkova JA, Makarov SS: NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling. Nature 1999; 401: 86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 19
    • 0033553466 scopus 로고    scopus 로고
    • Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways
    • Norris JL, Baldwin AS Jr: Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways. J Biol Chem 1999; 274: 13841-13846.
    • (1999) J Biol Chem , vol.274 , pp. 13841-13846
    • Norris, J.L.1    Baldwin Jr., A.S.2
  • 20
    • 0032514363 scopus 로고    scopus 로고
    • Activation of NF-kappa B by oncogenic Raf in HEK cells occurs through autocrine recruitment of the stress kinase cascade
    • Troppmair J, Hartkamp J, Rapp UR: Activation of NF-kappa B by oncogenic Raf in HEK cells occurs through autocrine recruitment of the stress kinase cascade. Oncogene 1998; 17: 685-690.
    • (1998) Oncogene , vol.17 , pp. 685-690
    • Troppmair, J.1    Hartkamp, J.2    Rapp, U.R.3
  • 21
    • 77954243178 scopus 로고    scopus 로고
    • NF-κB is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiation
    • in press
    • O'Neil B: NF-κB is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiation. Int J Radiat Oncol Biol Phys, in press.
    • Int J Radiat Oncol Biol Phys
    • O'Neil, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.