TGF-β1 up-regulates connective tissue growth factor expression in human granulosa cells through Smad and ERK1/2 signaling pathways

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Cheng, Jung Chien ^a   Chang, Hsun Ming ^a   Fang, Lanlan ^a,b   Sun, Ying Pu ^b   Leung, Peter C K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; CTGF PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR;

ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GRANULOSA CELL; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; GENE SILENCING; GENETICS; METABOLISM;

BENZAMIDES; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; DIOXOLES; FEMALE; GENE KNOCKDOWN TECHNIQUES; GRANULOSA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84940404776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126532     Document Type: Article

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