-
1
-
-
33746829275
-
Transforming growth factor-betas and vascular disorders
-
Bobik A: Transforming growth factor-betas and vascular disorders. Arterioscler Thromb Vasc Biol, 2006; 26: 1712-1720
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1712-1720
-
-
Bobik, A.1
-
2
-
-
4744371004
-
Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques
-
Cipollone F, Fazia M, Mincione G, Iezzi A, Pini B, Cuccurullo C, Ucchino S, Spigonardo F, Di Nisio M, Cuccurullo F, Mezzetti A, Porreca E: Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques. Stroke, 2004; 35: 2253-2257
-
(2004)
Stroke
, vol.35
, pp. 2253-2257
-
-
Cipollone, F.1
Fazia, M.2
Mincione, G.3
Iezzi, A.4
Pini, B.5
Cuccurullo, C.6
Ucchino, S.7
Spigonardo, F.8
di Nisio, M.9
Cuccurullo, F.10
Mezzetti, A.11
Porreca, E.12
-
3
-
-
0026055366
-
Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
-
Bradham DM, Igarashi A, Potter RL, Grotendorst GR: Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol, 1991; 114: 1285-1294
-
(1991)
J Cell Biol
, vol.114
, pp. 1285-1294
-
-
Bradham, D.M.1
Igarashi, A.2
Potter, R.L.3
Grotendorst, G.R.4
-
5
-
-
0031849452
-
Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cells
-
Shimo T, Nakanishi T, Kimura Y, Nishida T, Ishizeki K, Matsumura T, Takigawa M: Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cells. J Biochem, 1998; 124: 130-140
-
(1998)
J Biochem
, vol.124
, pp. 130-140
-
-
Shimo, T.1
Nakanishi, T.2
Kimura, Y.3
Nishida, T.4
Ishizeki, K.5
Matsumura, T.6
Takigawa, M.7
-
6
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J: TGF-beta signal transduction. Annu Rev Biochem, 1998; 67: 753-791
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
7
-
-
0034030142
-
TGF-beta signaling by Smad proteins
-
Miyazono K: TGF-beta signaling by Smad proteins. Cytokine Growth Factor Rev, 2000; 11: 15-22
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 15-22
-
-
Miyazono, K.1
-
8
-
-
0033956131
-
Signaling inputs converge on nuclear effectors in TGF-beta signaling
-
ten Dijke P, Miyazono K, Heldin CH: Signaling inputs converge on nuclear effectors in TGF-beta signaling. Trends Biochem Sci, 2000; 25: 64-70
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 64-70
-
-
ten Dijke, P.1
Miyazono, K.2
Heldin, C.H.3
-
9
-
-
0034016101
-
Positive and negative regulation of TGFbeta signaling
-
Miyazono K: Positive and negative regulation of TGFbeta signaling. J Cell Sci, 2000; 113 (Pt 7): 1101-1109
-
(2000)
J Cell Sci
, vol.113
, Issue.Pt 7
, pp. 1101-1109
-
-
Miyazono, K.1
-
10
-
-
0033515620
-
A Smad transcriptional corepressor
-
Wotton D, Lo RS, Lee S, Massague J: A Smad transcriptional corepressor. Cell, 1999; 97: 29-39
-
(1999)
Cell
, vol.97
, pp. 29-39
-
-
Wotton, D.1
Lo, R.S.2
Lee, S.3
Massague, J.4
-
11
-
-
0033521032
-
Kawabata M: C-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads
-
Akiyoshi S, Inoue H, Hanai J, Kusanagi K, Nemoto N, Miyazono K, Kawabata M: c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads. J Biol Chem, 1999; 274: 35269-35277
-
(1999)
J Biol Chem
, vol.274
, pp. 35269-35277
-
-
Akiyoshi, S.1
Inoue, H.2
Hanai, J.3
Kusanagi, K.4
Nemoto, N.5
Miyazono, K.6
-
12
-
-
0033200361
-
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling
-
Luo K, Stroschein SL, Wang W, Chen D, Martens E, Zhou S, Zhou Q: The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes Dev, 1999; 13: 2196-2206
-
(1999)
Genes Dev
, vol.13
, pp. 2196-2206
-
-
Luo, K.1
Stroschein, S.L.2
Wang, W.3
Chen, D.4
Martens, E.5
Zhou, S.6
Zhou, Q.7
-
13
-
-
0033595704
-
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
-
Stroschein SL, Wang W, Zhou S, Zhou Q, Luo K: Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science, 1999; 286: 771-774
-
(1999)
Science
, vol.286
, pp. 771-774
-
-
Stroschein, S.L.1
Wang, W.2
Zhou, S.3
Zhou, Q.4
Luo, K.5
-
14
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T: Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell, 1997; 89: 755-764
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
15
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G: Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell, 1997; 89: 747-754
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
16
-
-
0036021077
-
Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5
-
Nishimura R, Hata K, Harris SE, Ikeda F, Yoneda T: Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5. Bone, 2002; 31: 303-312
-
(2002)
Bone
, vol.31
, pp. 303-312
-
-
Nishimura, R.1
Hata, K.2
Harris, S.E.3
Ikeda, F.4
Yoneda, T.5
-
17
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ: Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell, 1997; 89: 765-771
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
18
-
-
15444351110
-
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
-
Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, Lindhout D, Cole WG, Henn W, Knoll JH, Owen MJ, Mertelsmann R, Zabel BU, Olsen BR: Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell, 1997; 89: 773-779
-
(1997)
Cell
, vol.89
, pp. 773-779
-
-
Mundlos, S.1
Otto, F.2
Mundlos, C.3
Mulliken, J.B.4
Aylsworth, A.S.5
Albright, S.6
Lindhout, D.7
Cole, W.G.8
Henn, W.9
Knoll, J.H.10
Owen, M.J.11
Mertelsmann, R.12
Zabel, B.U.13
Olsen, B.R.14
-
19
-
-
38549133940
-
Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells
-
Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, Iso T, Komori T, Arai M, Kurabayashi M: Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells. Mol Cell Biol, 2008; 28: 1147-1160
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1147-1160
-
-
Tanaka, T.1
Sato, H.2
Doi, H.3
Yoshida, C.A.4
Shimizu, T.5
Matsui, H.6
Yamazaki, M.7
Akiyama, H.8
Kawai-Kowase, K.9
Iso, T.10
Komori, T.11
Arai, M.12
Kurabayashi, M.13
-
20
-
-
0032528041
-
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors
-
Kawabata M, Inoue H, Hanyu A, Imamura T, Miyazono K: Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors. EMBO J, 1998; 17: 4056-4065
-
(1998)
EMBO J
, vol.17
, pp. 4056-4065
-
-
Kawabata, M.1
Inoue, H.2
Hanyu, A.3
Imamura, T.4
Miyazono, K.5
-
21
-
-
0032516862
-
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer
-
Jonk LJ, Itoh S, Heldin CH, ten Dijke P, Kruijer W: Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer. J Biol Chem, 1998; 273: 21145-21152
-
(1998)
J Biol Chem
, vol.273
, pp. 21145-21152
-
-
Jonk, L.J.1
Itoh, S.2
Heldin, C.H.3
ten Dijke, P.4
Kruijer, W.5
-
22
-
-
33744961538
-
Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase
-
Tanaka T, Nishimura D, Wu RC, Amano M, Iso T, Kedes L, Nishida H, Kaibuchi K, Hamamori Y: Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase. J Biol Chem, 2006; 281: 15320-15329
-
(2006)
J Biol Chem
, vol.281
, pp. 15320-15329
-
-
Tanaka, T.1
Nishimura, D.2
Wu, R.C.3
Amano, M.4
Iso, T.5
Kedes, L.6
Nishida, H.7
Kaibuchi, K.8
Hamamori, Y.9
-
23
-
-
33749401164
-
Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway
-
Doi H, Iso T, Sato H, Yamazaki M, Matsui H, Tanaka T, Manabe I, Arai M, Nagai R, Kurabayashi M: Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway. J Biol Chem, 2006; 281: 28555-28564
-
(2006)
J Biol Chem
, vol.281
, pp. 28555-28564
-
-
Doi, H.1
Iso, T.2
Sato, H.3
Yamazaki, M.4
Matsui, H.5
Tanaka, T.6
Manabe, I.7
Arai, M.8
Nagai, R.9
Kurabayashi, M.10
-
24
-
-
0032442852
-
Smads: Transcriptional activators of TGF-beta responses
-
Derynck R, Zhang Y, Feng XH: Smads: transcriptional activators of TGF-beta responses. Cell, 1998; 95: 737-740
-
(1998)
Cell
, vol.95
, pp. 737-740
-
-
Derynck, R.1
Zhang, Y.2
Feng, X.H.3
-
25
-
-
0034644472
-
TGFbeta signaling in growth control, cancer, and heritable disorders
-
Massague J, Blain SW, Lo RS: TGFbeta signaling in growth control, cancer, and heritable disorders. Cell, 2000; 103: 295-309
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
26
-
-
0035341209
-
TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
-
Alliston T, Choy L, Ducy P, Karsenty G, Derynck R: TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. EMBO J, 2001; 20: 2254-2272
-
(2001)
EMBO J
, vol.20
, pp. 2254-2272
-
-
Alliston, T.1
Choy, L.2
Ducy, P.3
Karsenty, G.4
Derynck, R.5
-
27
-
-
0034641617
-
A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia
-
Zhang YW, Yasui N, Ito K, Huang G, Fujii M, Hanai J, Nogami H, Ochi T, Miyazono K, Ito Y: A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia. Proc Natl Acad Sci U S A, 2000; 97: 10549-10554
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10549-10554
-
-
Zhang, Y.W.1
Yasui, N.2
Ito, K.3
Huang, G.4
Fujii, M.5
Hanai, J.6
Nogami, H.7
Ochi, T.8
Miyazono, K.9
Ito, Y.10
-
28
-
-
0036840499
-
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21 (CIP1/WAF1) promoter
-
Westendorf JJ, Zaidi SK, Cascino JE, Kahler R, van Wijnen AJ, Lian JB, Yoshida M, Stein GS, Li X: Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21 (CIP1/WAF1) promoter. Mol Cell Biol, 2002; 22: 7982-7992
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7982-7992
-
-
Westendorf, J.J.1
Zaidi, S.K.2
Cascino, J.E.3
Kahler, R.4
van Wijnen, A.J.5
Lian, J.B.6
Yoshida, M.7
Stein, G.S.8
Li, X.9
-
29
-
-
4744349390
-
Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation
-
Schroeder TM, Kahler RA, Li X, Westendorf JJ: Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation. J Biol Chem, 2004; 279: 41998-42007
-
(2004)
J Biol Chem
, vol.279
, pp. 41998-42007
-
-
Schroeder, T.M.1
Kahler, R.A.2
Li, X.3
Westendorf, J.J.4
-
30
-
-
8344261349
-
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
-
Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN: Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell, 2004; 119: 555-566
-
(2004)
Cell
, vol.119
, pp. 555-566
-
-
Vega, R.B.1
Matsuda, K.2
Oh, J.3
Barbosa, A.C.4
Yang, X.5
Meadows, E.6
McAnally, J.7
Pomajzl, C.8
Shelton, J.M.9
Richardson, J.A.10
Karsenty, G.11
Olson, E.N.12
-
31
-
-
33645981257
-
Transcriptional co-repressors of Runx2
-
Westendorf JJ: Transcriptional co-repressors of Runx2. J Cell Biochem, 2006; 98: 54-64
-
(2006)
J Cell Biochem
, vol.98
, pp. 54-64
-
-
Westendorf, J.J.1
-
32
-
-
0038639297
-
A DNA-binding-independent pathway of repression by the Drosophila Runt protein
-
Vander Zwan CJ, Wheeler JC, Li LH, Tracey WD, Gergen JP: A DNA-binding-independent pathway of repression by the Drosophila Runt protein. Blood Cells Mol Dis, 2003; 30: 207-222
-
(2003)
Blood Cells Mol Dis
, vol.30
, pp. 207-222
-
-
Vander, Z.C.J.1
Wheeler, J.C.2
Li, L.H.3
Tracey, W.D.4
Gergen, J.P.5
-
33
-
-
0034460993
-
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
-
Lee KS, Kim HJ, Li QL, Chi XZ, Ueta C, Komori T, Wozney JM, Kim EG, Choi JY, Ryoo HM, Bae SC: Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol Cell Biol, 2000; 20: 8783-8792
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8783-8792
-
-
Lee, K.S.1
Kim, H.J.2
Li, Q.L.3
Chi, X.Z.4
Ueta, C.5
Komori, T.6
Wozney, J.M.7
Kim, E.G.8
Choi, J.Y.9
Ryoo, H.M.10
Bae, S.C.11
-
34
-
-
0037062446
-
Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites
-
Zaidi SK, Sullivan AJ, van Wijnen AJ, Stein JL, Stein GS, Lian JB: Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites. Proceedings of the National Academy of Sciences of the United States of America, 2002; 99: 8048-8053
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 8048-8053
-
-
Zaidi, S.K.1
Sullivan, A.J.2
van Wijnen, A.J.3
Stein, J.L.4
Stein, G.S.5
Lian, J.B.6
-
35
-
-
20144365699
-
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription
-
Afzal F, Pratap J, Ito K, Ito Y, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Javed A: Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. J Cell Physiol, 2005; 204: 63-72
-
(2005)
J Cell Physiol
, vol.204
, pp. 63-72
-
-
Afzal, F.1
Pratap, J.2
Ito, K.3
Ito, Y.4
Stein, J.L.5
van Wijnen, A.J.6
Stein, G.S.7
Lian, J.B.8
Javed, A.9
-
36
-
-
3042549099
-
Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells
-
Selvamurugan N, Kwok S, Partridge NC: Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells. J Biol Chem, 2004; 279: 27764-27773
-
(2004)
J Biol Chem
, vol.279
, pp. 27764-27773
-
-
Selvamurugan, N.1
Kwok, S.2
Partridge, N.C.3
-
37
-
-
23044448510
-
Repression of Runx2 function by TGF-beta through recruitment of class β histone deacetylases by Smad3
-
Kang JS, Alliston T, Delston R, Derynck R: Repression of Runx2 function by TGF-beta through recruitment of class β histone deacetylases by Smad3. Embo Journal, 2005; 24: 2543-2555
-
(2005)
Embo Journal
, vol.24
, pp. 2543-2555
-
-
Kang, J.S.1
Alliston, T.2
Delston, R.3
Derynck, R.4
-
38
-
-
21044456200
-
Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development
-
Yamaai T, Nakanishi T, Asano M, Nawachi K, Yoshimichi G, Ohyama K, Komori T, Sugimoto T, Takigawa M: Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development. J Bone Miner Metab, 2005; 23: 280-288
-
(2005)
J Bone Miner Metab
, vol.23
, pp. 280-288
-
-
Yamaai, T.1
Nakanishi, T.2
Asano, M.3
Nawachi, K.4
Yoshimichi, G.5
Ohyama, K.6
Komori, T.7
Sugimoto, T.8
Takigawa, M.9
-
39
-
-
0036378148
-
CTGF expression in mesangial cells: Involvement of SMADs, MAP kinase, and PKC
-
Chen Y, Blom IE, Sa S, Goldschmeding R, Abraham DJ, Leask A: CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. Kidney Int, 2002; 62: 1149-1159
-
(2002)
Kidney Int
, vol.62
, pp. 1149-1159
-
-
Chen, Y.1
Blom, I.E.2
Sa, S.3
Goldschmeding, R.4
Abraham, D.J.5
Leask, A.6
-
40
-
-
0038400997
-
In or out? The dynamics of Smad nucleocytoplasmic shuttling
-
Reguly T, Wrana JL: In or out? The dynamics of Smad nucleocytoplasmic shuttling. Trends Cell Biol, 2003; 13: 216-220
-
(2003)
Trends Cell Biol
, vol.13
, pp. 216-220
-
-
Reguly, T.1
Wrana, J.L.2
-
41
-
-
3242799550
-
Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis
-
Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, Stampfli M, Lavery C, Margetts PJ, Roberts AB, Gauldie J: Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol, 2004; 173: 2099-2108
-
(2004)
J Immunol
, vol.173
, pp. 2099-2108
-
-
Bonniaud, P.1
Kolb, M.2
Galt, T.3
Robertson, J.4
Robbins, C.5
Stampfli, M.6
Lavery, C.7
Margetts, P.J.8
Roberts, A.B.9
Gauldie, J.10
-
42
-
-
77954222469
-
Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: Role of Smad and activator protein 1 signaling
-
Tran CM, Markova D, Smith HE, Susarla B, Ponnappan RK, Anderson DG, Symes A, Shapiro IM, Risbud MV: Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling. Arthritis Rheum, 2010; 62: 1983-1992
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1983-1992
-
-
Tran, C.M.1
Markova, D.2
Smith, H.E.3
Susarla, B.4
Ponnappan, R.K.5
Anderson, D.G.6
Symes, A.7
Shapiro, I.M.8
Risbud, M.V.9
-
43
-
-
0035815683
-
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
-
Holmes A, Abraham DJ, Sa S, Shiwen X, Black CM, Leask A: CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem, 2001; 276: 10594-10601
-
(2001)
J Biol Chem
, vol.276
, pp. 10594-10601
-
-
Holmes, A.1
Abraham, D.J.2
Sa, S.3
Shiwen, X.4
Black, C.M.5
Leask, A.6
-
44
-
-
62749139477
-
TNF-alpha suppressed TGFbeta-induced CTGF expression by switching the binding preference of p300 from Smad4 to p65
-
Yu F, Chou CW, Chen CC: TNF-alpha suppressed TGFbeta-induced CTGF expression by switching the binding preference of p300 from Smad4 to p65. Cell Signal, 2009; 21: 867-872
-
(2009)
Cell Signal
, vol.21
, pp. 867-872
-
-
Yu, F.1
Chou, C.W.2
Chen, C.C.3
-
45
-
-
77954894569
-
Inhibition of connective tissue growth factor/CCN2 expression in human dermal fibroblasts by interleukin-1alpha and beta
-
Nowinski D, Koskela A, Kiwanuka E, Bostrom M, Gerdin B, Ivarsson M: Inhibition of connective tissue growth factor/CCN2 expression in human dermal fibroblasts by interleukin-1alpha and beta. J Cell Biochem, 2010; 110: 1226-1233
-
(2010)
J Cell Biochem
, vol.110
, pp. 1226-1233
-
-
Nowinski, D.1
Koskela, A.2
Kiwanuka, E.3
Bostrom, M.4
Gerdin, B.5
Ivarsson, M.6
-
46
-
-
0035824518
-
Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3
-
Fu M, Zhang J, Zhu X, Myles DE, Willson TM, Liu X, Chen YE: Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3. J Biol Chem, 2001; 276: 45888-45894
-
(2001)
J Biol Chem
, vol.276
, pp. 45888-45894
-
-
Fu, M.1
Zhang, J.2
Zhu, X.3
Myles, D.E.4
Willson, T.M.5
Liu, X.6
Chen, Y.E.7
-
47
-
-
77952469124
-
Effects of PPAR gamma ligands on TGF-beta1-induced epithelialmesenchymal transition in alveolar epithelial cells
-
Tan X, Dagher H, Hutton CA, Bourke JE: Effects of PPAR gamma ligands on TGF-beta1-induced epithelialmesenchymal transition in alveolar epithelial cells. Respir Res, 2010; 11: 21
-
(2010)
Respir Res
, vol.11
, pp. 21
-
-
Tan, X.1
Dagher, H.2
Hutton, C.A.3
Bourke, J.E.4
-
48
-
-
0038704997
-
Combinatorial control of smooth muscle-specific gene expression
-
Kumar MS, Owens GK: Combinatorial control of smooth muscle-specific gene expression. Arterioscler Thromb Vasc Biol, 2003; 23: 737-747
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 737-747
-
-
Kumar, M.S.1
Owens, G.K.2
-
49
-
-
44649133999
-
Vascular calcification: Pathobiology of a multifaceted disease
-
Demer LL, Tintut Y: Vascular calcification: pathobiology of a multifaceted disease. Circulation, 2008; 117: 2938-2948
-
(2008)
Circulation
, vol.117
, pp. 2938-2948
-
-
Demer, L.L.1
Tintut, Y.2
-
50
-
-
33745962708
-
Molecular mechanisms of vascular calcification: Lessons learned from the aorta
-
Shao JS, Cai J, Towler DA: Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol, 2006; 26: 1423-1430
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1423-1430
-
-
Shao, J.S.1
Cai, J.2
Towler, D.A.3
-
51
-
-
0034730291
-
Phosphate regulation of vascular smooth muscle cell calcification
-
Jono S, McKee MD, Murry CE, Shioi A, Nishizawa Y, Mori K, Morii H, Giachelli CM: Phosphate regulation of vascular smooth muscle cell calcification. Circ Res, 2000; 87: E10-17
-
(2000)
Circ Res
, vol.87
-
-
Jono, S.1
McKee, M.D.2
Murry, C.E.3
Shioi, A.4
Nishizawa, Y.5
Mori, K.6
Morii, H.7
Giachelli, C.M.8
-
52
-
-
77950187706
-
Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells
-
Nakahara T, Sato H, Shimizu T, Tanaka T, Matsui H, Kawai-Kowase K, Sato M, Iso T, Arai M, Kurabayashi M: Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells. Biochem Biophys Res Commun, 2010; 394: 243-248
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 243-248
-
-
Nakahara, T.1
Sato, H.2
Shimizu, T.3
Tanaka, T.4
Matsui, H.5
Kawai-Kowase, K.6
Sato, M.7
Iso, T.8
Arai, M.9
Kurabayashi, M.10
-
53
-
-
16944364613
-
Human connective tissue growth factor is expressed in advanced atherosclerotic lesions
-
Oemar BS, Werner A, Garnier JM, Do DD, Godoy N, Nauck M, Marz W, Rupp J, Pech M, Luscher TF: Human connective tissue growth factor is expressed in advanced atherosclerotic lesions. Circulation, 1997; 95: 831-839
-
(1997)
Circulation
, vol.95
, pp. 831-839
-
-
Oemar, B.S.1
Werner, A.2
Garnier, J.M.3
Do, D.D.4
Godoy, N.5
Nauck, M.6
Marz, W.7
Rupp, J.8
Pech, M.9
Luscher, T.F.10
-
54
-
-
18244391728
-
Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro
-
Cicha I, Yilmaz A, Klein M, Raithel D, Brigstock DR, Daniel WG, Goppelt-Struebe M, Garlichs CD: Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro. Arterioscler Thromb Vasc Biol, 2005; 25: 1008-1013
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1008-1013
-
-
Cicha, I.1
Yilmaz, A.2
Klein, M.3
Raithel, D.4
Brigstock, D.R.5
Daniel, W.G.6
Goppelt-Struebe, M.7
Garlichs, C.D.8
-
55
-
-
0033601275
-
Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7
-
Hishikawa K, Oemar BS, Tanner FC, Nakaki T, Luscher TF, Fujii T: Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7. J Biol Chem, 1999; 274: 37461-37466
-
(1999)
J Biol Chem
, vol.274
, pp. 37461-37466
-
-
Hishikawa, K.1
Oemar, B.S.2
Tanner, F.C.3
Nakaki, T.4
Luscher, T.F.5
Fujii, T.6
|