-
1
-
-
27144489108
-
Protein database searches using compositionally adjusted substitution matrices
-
Altschul SF, Wootton JC, Gertz E.M., Agarwala R., Morgulis A, Schäffer AA, and Yu YK (2005) Protein database searches using compositionally adjusted substitution matrices. FEBS J 272: 5101-5109.
-
(2005)
FEBS J
, vol.272
, pp. 5101-5109
-
-
Altschul, S.F.1
Wootton, J.C.2
Gertz, E.M.3
Agarwala, R.4
Morgulis, A.5
Schäffer, A.A.6
Yu, Y.K.7
-
2
-
-
0034463602
-
Drug enterocyte adducts: Possible causal factor for diclofenac enteropathy in rats
-
Atchison CR, West AB, Balakumaran A, Hargus S.J., Pohl LR, Daiker DH, Aronson JF, Hoffmann W.E., Shipp BK, and Treinen-Moslen M (2000) Drug enterocyte adducts: possible causal factor for diclofenac enteropathy in rats. Gastroenterology 119:1537-1547.
-
(2000)
Gastroenterology
, vol.119
, pp. 1537-1547
-
-
Atchison, C.R.1
West, A.B.2
Balakumaran, A.3
Hargus, S.J.4
Pohl, L.R.5
Daiker, D.H.6
Aronson, J.F.7
Hoffmann, W.E.8
Shipp, B.K.9
Treinen-Moslen, M.10
-
3
-
-
0029058466
-
Role of proinflammatory cytokines in acetaminophen hepatotoxicity
-
Blazka ME, Wilmer JL, Holladay S.D., Wilson RE, and Luster MI (1995) Role of proinflammatory cytokines in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 133:43-52.
-
(1995)
Toxicol Appl Pharmacol
, vol.133
, pp. 43-52
-
-
Blazka, M.E.1
Wilmer, J.L.2
Holladay, S.D.3
Wilson, R.E.4
Luster, M.I.5
-
4
-
-
22344452137
-
Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps)
-
Cheng X, Maher J, Chen C., and Klaassen CD (2005) Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps). Drug Metab Dispos 33:1062-1073.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1062-1073
-
-
Cheng, X.1
Maher, J.2
Chen, C.3
Klaassen, C.D.4
-
5
-
-
33846230114
-
Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
-
Daly AK, Aithal GP, Leathart J.B., Swainsbury RA, Dang TS, and Day CP (2007) Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 132:272-281.
-
(2007)
Gastroenterology
, vol.132
, pp. 272-281
-
-
Daly, A.K.1
Aithal, G.P.2
Leathart, J.B.3
Swainsbury, R.A.4
Dang, T.S.5
Day, C.P.6
-
6
-
-
3142557936
-
Acute and clinically relevant drug-induced liver injury: A population based case-control study
-
de Abajo F.J., Montero D, Madurga M., and García Rodríguez LA (2004) Acute and clinically relevant drug-induced liver injury: a population based case-control study. Br J Clin Pharmacol 58:71-80.
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 71-80
-
-
De Abajo, F.J.1
Montero, D.2
Madurga, M.3
García Rodríguez, L.A.4
-
8
-
-
84907993610
-
Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine
-
Drozdzik M, Gröer C, Penski J., Lapczuk J, Ostrowski M, Lai Y., Prasad B, Unadkat JD, Siegmund W, and Oswald S (2014) Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine. Mol Pharm 11:3547-3555.
-
(2014)
Mol Pharm
, vol.11
, pp. 3547-3555
-
-
Drozdzik, M.1
Gröer, C.2
Penski, J.3
Lapczuk, J.4
Ostrowski, M.5
Lai, Y.6
Prasad, B.7
Unadkat, J.D.8
Siegmund, W.9
Oswald, S.10
-
9
-
-
0032826052
-
Disposition and chemical stability of telmisartan 1-O-acylglucuronide
-
Ebner T, Heinzel G, Prox A., Beschke K, and Wachsmuth H (1999) Disposition and chemical stability of telmisartan 1-O-acylglucuronide. Drug Metab Dispos 27:1143-1149.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 1143-1149
-
-
Ebner, T.1
Heinzel, G.2
Prox, A.3
Beschke, K.4
Wachsmuth, H.5
-
10
-
-
34249939004
-
Genetic variations of the ABC transporter gene ABCC3 in a Japanese population
-
Fukushima-Uesaka H., Saito Y, Maekawa K., Hasegawa R, Suzuki K, Yanagawa T., Kajio H, Kuzuya N, Noda M., and Yasuda K, et al. (2007) Genetic variations of the ABC transporter gene ABCC3 in a Japanese population. Drug Metab Pharmacokinet 22:129-135.
-
(2007)
Drug Metab Pharmacokinet
, vol.22
, pp. 129-135
-
-
Fukushima-Uesaka, H.1
Saito, Y.2
Maekawa, K.3
Hasegawa, R.4
Suzuki, K.5
Yanagawa, T.6
Kajio, H.7
Kuzuya, N.8
Noda, M.9
Yasuda, K.10
-
11
-
-
0242438629
-
Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS
-
Gómez-Lechón MJ, Ponsoda X, O'Connor E, Donato T, Castell JV, and Jover R (2003) Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS. Biochem Pharmacol 66:2155-2167.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 2155-2167
-
-
Gómez-Lechón, M.J.1
Ponsoda, X.2
O'Connor, E.3
Donato, T.4
Castell, J.V.5
Jover, R.6
-
12
-
-
0028815559
-
Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac
-
Hargus SJ, Martin BM, George J.W., and Pohl LR (1995) Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac. Chem Res Toxicol 8:993-996.
-
(1995)
Chem Res Toxicol
, vol.8
, pp. 993-996
-
-
Hargus, S.J.1
Martin, B.M.2
George, J.W.3
Pohl, L.R.4
-
13
-
-
0035879827
-
Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death
-
Hickey EJ, Raje RR, Reid V.E., Gross SM, and Ray SD (2001) Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death. Free Radic Biol Med 31:139-152.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 139-152
-
-
Hickey, E.J.1
Raje, R.R.2
Reid, V.E.3
Gross, S.M.4
Ray, S.D.5
-
14
-
-
76149142438
-
Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance
-
Huang L, Berry L, Ganga S., Janosky B, Chen A, Roberts J., Colletti AE, and Lin MH (2010) Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance. Drug Metab Dispos 38:223-231.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 223-231
-
-
Huang, L.1
Berry, L.2
Ganga, S.3
Janosky, B.4
Chen, A.5
Roberts, J.6
Colletti, A.E.7
Lin, M.H.8
-
15
-
-
41549098278
-
Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide
-
Ishiguro N, Maeda K, Saito A., Kishimoto W, Matsushima S, Ebner T., Roth W, Igarashi T, and Sugiyama Y (2008) Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide. Drug Metab Dispos 36:796-805.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 796-805
-
-
Ishiguro, N.1
Maeda, K.2
Saito, A.3
Kishimoto, W.4
Matsushima, S.5
Ebner, T.6
Roth, W.7
Igarashi, T.8
Sugiyama, Y.9
-
16
-
-
2442635266
-
Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac
-
Kenny JR, Maggs JL, Meng X, Sinnott D., Clarke SE, Park BK, and Stachulski AV (2004) Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac. J Med Chem 47:2816-2825.
-
(2004)
J Med Chem
, vol.47
, pp. 2816-2825
-
-
Kenny, J.R.1
Maggs, J.L.2
Meng, X.3
Sinnott, D.4
Clarke, S.E.5
Park, B.K.6
Stachulski, A.V.7
-
17
-
-
0035038561
-
Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac
-
King C, Tang W, Ngui J., Tephly T, and Braun M (2001) Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac. Toxicol Sci 61:49-53.
-
(2001)
Toxicol Sci
, vol.61
, pp. 49-53
-
-
King, C.1
Tang, W.2
Ngui, J.3
Tephly, T.4
Braun, M.5
-
18
-
-
53049099460
-
Functional analysis of non-synonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3
-
Kobayashi K, Ito K, Takada T., Sugiyama Y, and Suzuki H (2008) Functional analysis of non-synonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3. Pharmacogenet Genomics 18:823-833.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 823-833
-
-
Kobayashi, K.1
Ito, K.2
Takada, T.3
Sugiyama, Y.4
Suzuki, H.5
-
19
-
-
0027269444
-
Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes
-
Kretz-Rommel A and Boelsterli UA (1993) Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes. Toxicol Appl Pharmacol 120:155-161.
-
(1993)
Toxicol Appl Pharmacol
, vol.120
, pp. 155-161
-
-
Kretz-Rommel, A.1
Boelsterli, U.A.2
-
20
-
-
33947494603
-
Role of blood- and tissue-associated inducible nitric-oxide synthase in colonic inflammation
-
Krieglstein CF, Anthoni C, Cerwinka W.H., Stokes KY, Russell J, Grisham MB, and Granger DN (2007) Role of blood- and tissue-associated inducible nitric-oxide synthase in colonic inflammation. Am J Pathol 170:490-496.
-
(2007)
Am J Pathol
, vol.170
, pp. 490-496
-
-
Krieglstein, C.F.1
Anthoni, C.2
Cerwinka, W.H.3
Stokes, K.Y.4
Russell, J.5
Grisham, M.B.6
Granger, D.N.7
-
21
-
-
77950229800
-
Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters
-
Lagas JS, Sparidans RW, Wagenaar E, Beijnen J.H., and Schinkel AH (2010) Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters. Mol Pharmacol 77:687-694.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 687-694
-
-
Lagas, J.S.1
Sparidans, R.W.2
Wagenaar, E.3
Beijnen, J.H.4
Schinkel, A.H.5
-
22
-
-
58149477228
-
Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benz-bromarone
-
Lagas JS, van der Kruijssen CM, van de Wetering K, Beijnen JH, and Schinkel AH (2009) Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benz-bromarone. Drug Metab Dispos 37:129-136.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 129-136
-
-
Lagas, J.S.1
Van Der Kruijssen, C.M.2
Van De Wetering, K.3
Beijnen, J.H.4
Schinkel, A.H.5
-
23
-
-
12144290373
-
Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver
-
Lang T, Hitzl M, Burk O., Mornhinweg E, Keil A, Kerb R., Klein K, Zanger UM, Eichelbaum M, and Fromm MF (2004) Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver. Pharmacogenetics 14:155-164.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 155-164
-
-
Lang, T.1
Hitzl, M.2
Burk, O.3
Mornhinweg, E.4
Keil, A.5
Kerb, R.6
Klein, K.7
Zanger, U.M.8
Eichelbaum, M.9
Fromm, M.F.10
-
24
-
-
33845211478
-
Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes
-
Lim MS, Lim PL, Gupta R, and Boelsterli UA (2006) Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes. Toxicol Appl Pharmacol 217: 322-331.
-
(2006)
Toxicol Appl Pharmacol
, vol.217
, pp. 322-331
-
-
Lim, M.S.1
Lim, P.L.2
Gupta, R.3
Boelsterli, U.A.4
-
25
-
-
27744574913
-
Altered disposition of acetaminophen in mice with a disruption of the mrp3 gene
-
Manautou JE, de Waart DR, Kunne C, Zelcer N, Goedken M., Borst P, and Elferink RO (2005) Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene. Hepatology 42:1091-1098.
-
(2005)
Hepatology
, vol.42
, pp. 1091-1098
-
-
Manautou, J.E.1
De Waart, D.R.2
Kunne, C.3
Zelcer, N.4
Goedken, M.5
Borst, P.6
Elferink, R.O.7
-
26
-
-
0027949148
-
Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity
-
Manautou JE, Hoivik DJ, Tveit A, Hart S.G., Khairallah EA, and Cohen SD (1994) Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity. Toxicol Appl Pharmacol 129:252-263.
-
(1994)
Toxicol Appl Pharmacol
, vol.129
, pp. 252-263
-
-
Manautou, J.E.1
Hoivik, D.J.2
Tveit, A.3
Hart, S.G.4
Khairallah, E.A.5
Cohen, S.D.6
-
27
-
-
0033011299
-
Diclofenac-potassium in migraine: A review
-
McNeely W and Goa KL (1999) Diclofenac-potassium in migraine: a review. Drugs 57: 991-1003.
-
(1999)
Drugs
, vol.57
, pp. 991-1003
-
-
McNeely, W.1
Goa, K.L.2
-
28
-
-
0017832745
-
Pharmacological properties of diclofenac sodium and its metabolites
-
Menassé R, Hedwall PR, Kraetz J, Pericin C, Riesterer L, Sallmann A, Ziel R, and Jaques R (1978) Pharmacological properties of diclofenac sodium and its metabolites. Scand J Rheumatol Suppl 22:5-16.
-
(1978)
Scand J Rheumatol Suppl
, vol.22
, pp. 5-16
-
-
Menassé, R.1
Hedwall, P.R.2
Kraetz, J.3
Pericin, C.4
Riesterer, L.5
Sallmann, A.6
Ziel, R.7
Jaques, R.8
-
29
-
-
0019382757
-
The "Swiss roll": A simple technique for histological studies of the rodent intestine
-
Moolenbeek C and Ruitenberg EJ (1981) The "Swiss roll": a simple technique for histological studies of the rodent intestine. Lab Anim 15:57-59.
-
(1981)
Lab Anim
, vol.15
, pp. 57-59
-
-
Moolenbeek, C.1
Ruitenberg, E.J.2
-
31
-
-
72249084181
-
Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy
-
Ramirez-Alcantara V., LoGuidice A, and Boelsterli UA (2009) Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy. Am J Physiol Gastrointest Liver Physiol 297:G990-G998.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G990-G998
-
-
Ramirez-Alcantara, V.1
LoGuidice, A.2
Boelsterli, U.A.3
-
32
-
-
0018097789
-
Pharmacokinetics and metabolism of the antiinflammatory agent voltaren
-
Riess W, Stierlin H, Degen P., Faigle JW, Gérardin A, Moppert J., Sallmann A, Schmid K, Schweizer A., and Sulc M, et al. (1978) Pharmacokinetics and metabolism of the antiinflammatory agent Voltaren. Scand J Rheumatol Suppl 22:17-29.
-
(1978)
Scand J Rheumatol Suppl
, vol.22
, pp. 17-29
-
-
Riess, W.1
Stierlin, H.2
Degen, P.3
Faigle, J.W.4
Gérardin, A.5
Moppert, J.6
Sallmann, A.7
Schmid, K.8
Schweizer, A.9
Sulc, M.10
-
33
-
-
0035197972
-
In vivo perturbation of rat hepatocyte canalicular membrane function by diclofenac
-
Sallustio BC and Holbrook FL (2001) In vivo perturbation of rat hepatocyte canalicular membrane function by diclofenac. Drug Metab Dispos 29:1535-1538.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1535-1538
-
-
Sallustio, B.C.1
Holbrook, F.L.2
-
35
-
-
84855447409
-
Diclofenac metabolism in the mouse: Novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry
-
Sarda S, Page C, Pickup K., Schulz-Utermoehl T, and Wilson I (2012) Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry. Xenobiotica 42:179-194.
-
(2012)
Xenobiotica
, vol.42
, pp. 179-194
-
-
Sarda, S.1
Page, C.2
Pickup, K.3
Schulz-Utermoehl, T.4
Wilson, I.5
-
36
-
-
0031760270
-
Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats
-
Seitz S and Boelsterli UA (1998) Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats. Gastroenterology 115:1476-1482.
-
(1998)
Gastroenterology
, vol.115
, pp. 1476-1482
-
-
Seitz, S.1
Boelsterli, U.A.2
-
37
-
-
0031746239
-
Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2)
-
Seitz S, Kretz-Rommel A, Oude Elferink RP, and Boelsterli UA (1998) Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2). Chem Res Toxicol 11:513-519.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 513-519
-
-
Seitz, S.1
Kretz-Rommel, A.2
Oude Elferink, R.P.3
Boelsterli, U.A.4
-
38
-
-
33745165982
-
Oxidative stress and mrp2 internalization
-
Sekine S, Ito K, and Horie T (2006) Oxidative stress and Mrp2 internalization. Free Radic Biol Med 40:2166-2174.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 2166-2174
-
-
Sekine, S.1
Ito, K.2
Horie, T.3
-
39
-
-
0032965220
-
Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites
-
Tang W, Stearns RA, Bandiera S.M., Zhang Y., Raab C, Braun MP, Dean D.C., Pang J., Leung KH, and Doss GA, et al. (1999) Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites. Drug Metab Dispos 27:365-372.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 365-372
-
-
Tang, W.1
Stearns, R.A.2
Bandiera, S.M.3
Zhang, Y.4
Raab, C.5
Braun, M.P.6
Dean, D.C.7
Pang, J.8
Leung, K.H.9
Doss, G.A.10
-
40
-
-
42449122721
-
Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers
-
Tian X, Swift B, Zamek-Gliszczynski MJ, Belinsky MG, Kruh GD, and Brouwer KL (2008) Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers. Drug Metab Dispos 36:911-915.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 911-915
-
-
Tian, X.1
Swift, B.2
Zamek-Gliszczynski, M.J.3
Belinsky, M.G.4
Kruh, G.D.5
Brouwer, K.L.6
-
41
-
-
78751695197
-
Cardiovascular safety of non-steroidal anti-inflammatory drugs: Network metaanalysis
-
Trelle S, Reichenbach S, Wandel S., Hildebrand P, Tschannen B, Villiger P.M., Egger M., and Jüni P (2011) Cardiovascular safety of non-steroidal anti-inflammatory drugs: network metaanalysis. BMJ 342:c7086.
-
(2011)
BMJ
, vol.342
-
-
Trelle, S.1
Reichenbach, S.2
Wandel, S.3
Hildebrand, P.4
Tschannen, B.5
Villiger, P.M.6
Egger, M.7
Jüni, P.8
-
42
-
-
73149114172
-
Abcc2 (Mrp2), abcc3 (Mrp3), and abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo
-
Vlaming ML, van Esch A, Pala Z, Wagenaar E., van de Wetering K, van Tellingen O, and Schinkel AH (2009) Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo. Mol Cancer Ther 8:3350-3359.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3350-3359
-
-
Vlaming, M.L.1
Van Esch, A.2
Pala, Z.3
Wagenaar, E.4
Van De Wetering, K.5
Van Tellingen, O.6
Schinkel, A.H.7
-
43
-
-
55949135789
-
Prostaglandins, NSAIDs, and gastric mucosal protection: Why doesn't the stomach digest itself?
-
Wallace JL (2008) Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself? Physiol Rev 88:1547-1565.
-
(2008)
Physiol Rev
, vol.88
, pp. 1547-1565
-
-
Wallace, J.L.1
-
44
-
-
0018574044
-
The pharmacokinetics of diclofenac sodium following intravenous and oral administration
-
Willis JV, Kendall MJ, Flinn R.M., Thornhill DP, and Welling PG (1979) The pharmacokinetics of diclofenac sodium following intravenous and oral administration. Eur J Clin Pharmacol 16: 405-410.
-
(1979)
Eur J Clin Pharmacol
, vol.16
, pp. 405-410
-
-
Willis, J.V.1
Kendall, M.J.2
Flinn, R.M.3
Thornhill, D.P.4
Welling, P.G.5
-
45
-
-
33751199707
-
Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in abcc3-/- and abcc4-/- mice
-
Zamek-Gliszczynski M.J., Nezasa K, Tian X., Bridges AS, Lee K, Belinsky MG, Kruh G.D., and Brouwer KL (2006) Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice. J Pharmacol Exp Ther 319:1485-1491.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 1485-1491
-
-
Zamek-Gliszczynski, M.J.1
Nezasa, K.2
Tian, X.3
Bridges, A.S.4
Lee, K.5
Belinsky, M.G.6
Kruh, G.D.7
Brouwer, K.L.8
-
46
-
-
0037269403
-
Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal na+-dependent bile-acid transporter
-
Zelcer N, Saeki T, Bot I., Kuil A, and Borst P (2003) Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter. Biochem J 369:23-30.
-
(2003)
Biochem J
, vol.369
, pp. 23-30
-
-
Zelcer, N.1
Saeki, T.2
Bot, I.3
Kuil, A.4
Borst, P.5
-
47
-
-
0035824674
-
Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3)
-
Zelcer N, Saeki T, Reid G., Beijnen JH, and Borst P (2001) Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem 276:46400-46407.
-
(2001)
J Biol Chem
, vol.276
, pp. 46400-46407
-
-
Zelcer, N.1
Saeki, T.2
Reid, G.3
Beijnen, J.H.4
Borst, P.5
-
48
-
-
33644910207
-
Mice lacking mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
-
Zelcer N, van de Wetering K, de Waart R, Scheffer GL, Marschall HU, Wielinga PR, Kuil A, Kunne C, Smith A, and van der Valk M, et al. (2006) Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. J Hepatol 44: 768-775.
-
(2006)
J Hepatol
, vol.44
, pp. 768-775
-
-
Zelcer, N.1
Van De Wetering, K.2
De Waart, R.3
Scheffer, G.L.4
Marschall, H.U.5
Wielinga, P.R.6
Kuil, A.7
Kunne, C.8
Smith, A.9
Van Der Valk, M.10
|