Ameliorative effect of aspalathin and nothofagin from rooibos (Aspalathus linearis) on HMGB1-induced septic responses in vitro and in vivo

American Journal of Chinese Medicine

Volumn 43, Issue 5, 2015, Pages 991-1012

  Lee, Wonhwa ^a,b   Kim, Kyung Min ^b   Bae, Jong Sup ^a  

^a Research Institute of Pharmaceutical Sciences ^*  (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

Aspalathin; HMGB1; HUVEC; Inflammation; Nothofagin; Sepsis

Indexed keywords

ASPALATHIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HERBACEOUS AGENT; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NOTHOFAGIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CHALCONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CELL ADHESION; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HERBAL TEA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; SEPSIS; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; ASPALATHUS; C57BL MOUSE; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; PHYTOTHERAPY; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ASPALATHUS; CHALCONES; DISEASE MODELS, ANIMAL; HMGB1 PROTEIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; MALE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; PHYTOTHERAPY; SEPSIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84940377464     PISSN: 0192415X     EISSN: 17936853     Source Type: Journal    
DOI: 10.1142/S0192415X15500573     Document Type: Article

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