Autolysis loop restricts the specificity of activated protein C: Analysis by FRET and functional assays

Biophysical Chemistry

Volumn 134, Issue 3, 2008, Pages 239-245

  Qureshi, Shabir H ^a   Manithody, Chandrashekhara ^a   Bae, Jong Sup ^a   Yang, Likui ^a   Rezaie, Alireza R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activated protein C; Factor Xa; FRET; Protein S; Trypsin

Indexed keywords

ACTIVATED PROTEIN C; FLUORESCEIN; PROTEIN S; TRYPSIN;

ANISOTROPY; ANTICOAGULATION; ARTICLE; AUTOLYSIS; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; BINDING SITES; BIOLOGICAL ASSAY; CATALYSIS; ENZYME ACTIVATION; FACTOR VA; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; HYDROLYSIS; MUTATION; PROTEIN C; RECEPTOR, PAR-1; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 41449092543     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2008.02.012     Document Type: Article

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