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Volumn 87, Issue , 2015, Pages 263-273

Monoamine oxidase-A is an important source of oxidative stress and promotes cardiac dysfunction, apoptosis, and fibrosis in diabetic cardiomyopathy

Author keywords

Apoptosis; Cardiac dy sfunction; Diabetic cardiomyopathy; Freeradicals; Monoamine oxidase A; Oxidativestress

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 9; CATECHOLAMINE; CLORGYLINE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TROPONIN I; UNCOUPLING PROTEIN 3; AMINE OXIDASE (FLAVIN CONTAINING); ANTIOXIDANT; MONOAMINE OXIDASE INHIBITOR;

EID: 84940373910     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.06.025     Document Type: Article
Times cited : (73)

References (42)
  • 1
    • 33645280925 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: The search for a unifying hypothesis
    • I.G. Poornima, P. Parikh, and R.P. Shannon Diabetic cardiomyopathy: the search for a unifying hypothesis Circ. Res. 98 2006 596 605
    • (2006) Circ. Res. , vol.98 , pp. 596-605
    • Poornima, I.G.1    Parikh, P.2    Shannon, R.P.3
  • 2
    • 0032949682 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling
    • B. Swynghedauw Molecular mechanisms of myocardial remodeling Physiol. Rev. 79 1999 215 262
    • (1999) Physiol. Rev. , vol.79 , pp. 215-262
    • Swynghedauw, B.1
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • J.W. Baynes Role of oxidative stress in development of complications in diabetes Diabetes 40 1991 405 412
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 0028116420 scopus 로고
    • Weak antioxidant defenses make the heart a target for damage in copper-deficient rats
    • Y. Chen, J.T. Saari, and Y.J. Kang Weak antioxidant defenses make the heart a target for damage in copper-deficient rats Free Radic. Biol. Med. 17 1994 529 536
    • (1994) Free Radic. Biol. Med. , vol.17 , pp. 529-536
    • Chen, Y.1    Saari, J.T.2    Kang, Y.J.3
  • 5
    • 84879744608 scopus 로고    scopus 로고
    • Multiple antioxidants improve cardiac complications and inhibit cardiac cell death in streptozotocin-induced diabetic rats
    • S. Kumar, S. Prasad, and S.L. Sitasawad Multiple antioxidants improve cardiac complications and inhibit cardiac cell death in streptozotocin-induced diabetic rats PLoS One 8 2013 e67009
    • (2013) PLoS One , vol.8 , pp. e67009
    • Kumar, S.1    Prasad, S.2    Sitasawad, S.L.3
  • 6
    • 34147095113 scopus 로고    scopus 로고
    • Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine
    • Z. Guo, Z. Xia, J. Jiang, and J.H. McNeill Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine Am. J. Physiol. Heart Circ. Physiol 292 2007 H1728 H1736
    • (2007) Am. J. Physiol. Heart Circ. Physiol , vol.292 , pp. H1728-H1736
    • Guo, Z.1    Xia, Z.2    Jiang, J.3    McNeill, J.H.4
  • 7
    • 33749513188 scopus 로고    scopus 로고
    • Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy
    • L. Cai, Y. Wang, G. Zhou, T. Chen, Y. Song, X. Li, and et al. Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy J. Am. Coll. Cardiol. 48 2006 1688 1697
    • (2006) J. Am. Coll. Cardiol. , vol.48 , pp. 1688-1697
    • Cai, L.1    Wang, Y.2    Zhou, G.3    Chen, T.4    Song, Y.5    Li, X.6
  • 8
    • 0029085103 scopus 로고
    • Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: Influence of tocopherol as antioxidant
    • P. Rosen, T. Ballhausen, W. Bloch, and K. Addicks Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: influence of tocopherol as antioxidant Diabetologia 38 1995 1157 1168
    • (1995) Diabetologia , vol.38 , pp. 1157-1168
    • Rosen, P.1    Ballhausen, T.2    Bloch, W.3    Addicks, K.4
  • 9
    • 79957936379 scopus 로고    scopus 로고
    • Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury
    • N. Kaludercic, A. Carpi, R. Menabo, L.F. Di, and N. Paolocci Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury Biochim. Biophys. Acta 1813 2011 1323 1332
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1323-1332
    • Kaludercic, N.1    Carpi, A.2    Menabo, R.3    Di, L.F.4    Paolocci, N.5
  • 10
    • 74049129002 scopus 로고    scopus 로고
    • Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload
    • N. Kaludercic, E. Takimoto, T. Nagayama, N. Feng, E.W. Lai, D. Bedja, and et al. Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload Circ. Res. 106 2010 193 202
    • (2010) Circ. Res. , vol.106 , pp. 193-202
    • Kaludercic, N.1    Takimoto, E.2    Nagayama, T.3    Feng, N.4    Lai, E.W.5    Bedja, D.6
  • 11
    • 84870544267 scopus 로고    scopus 로고
    • P53-PGC-1alpha pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: Role in chronic left ventricular dysfunction in mice
    • C. Villeneuve, C. Guilbeau-Frugier, P. Sicard, O. Lairez, C. Ordener, T. Duparc, and et al. p53-PGC-1alpha pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice Antioxid. Redox Signaling 18 2013 5 18
    • (2013) Antioxid. Redox Signaling , vol.18 , pp. 5-18
    • Villeneuve, C.1    Guilbeau-Frugier, C.2    Sicard, P.3    Lairez, O.4    Ordener, C.5    Duparc, T.6
  • 12
    • 67649243697 scopus 로고    scopus 로고
    • The cardioprotective effects elicited by p66 (Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury
    • A. Carpi, R. Menabo, N. Kaludercic, P. Pelicci, L.F. Di, and M. Giorgio The cardioprotective effects elicited by p66 (Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury Biochim. Biophys. Acta 1787 2009 774 780
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 774-780
    • Carpi, A.1    Menabo, R.2    Kaludercic, N.3    Pelicci, P.4    Di, L.F.5    Giorgio, M.6
  • 13
    • 33644874936 scopus 로고    scopus 로고
    • Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and post ischemic myocardial injury
    • P. Bianchi, O. Kunduzova, E. Masini, C. Cambon, D. Bani, L. Raimondi, and et al. Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and post ischemic myocardial injury Circulation 112 2005 3297 3305
    • (2005) Circulation , vol.112 , pp. 3297-3305
    • Bianchi, P.1    Kunduzova, O.2    Masini, E.3    Cambon, C.4    Bani, D.5    Raimondi, L.6
  • 14
    • 33846047834 scopus 로고    scopus 로고
    • Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis
    • D. Pchejetski, O. Kunduzova, A. Dayon, D. Calise, M.H. Seguelas, N. Leducq, and et al. Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis Circ. Res. 100 2007 41 49
    • (2007) Circ. Res. , vol.100 , pp. 41-49
    • Pchejetski, D.1    Kunduzova, O.2    Dayon, A.3    Calise, D.4    Seguelas, M.H.5    Leducq, N.6
  • 15
    • 0022515815 scopus 로고
    • Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2. Cardiovascular system
    • C.A. Maggi, and A. Meli Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2. Cardiovascular system Experientia 42 1986 292 297
    • (1986) Experientia , vol.42 , pp. 292-297
    • Maggi, C.A.1    Meli, A.2
  • 16
    • 38549101542 scopus 로고    scopus 로고
    • Heart rate recovery after exercise is associated with resting QTc interval in young men
    • K.S. Heffernan, S.Y. Jae, and B. Fernhall Heart rate recovery after exercise is associated with resting QTc interval in young men Clin. Auton. Res. 17 2007 356 363
    • (2007) Clin. Auton. Res. , vol.17 , pp. 356-363
    • Heffernan, K.S.1    Jae, S.Y.2    Fernhall, B.3
  • 17
    • 0036815248 scopus 로고    scopus 로고
    • Pyrogallol-induced hepatotoxicity in rats: A model to evaluate antioxidant hepatoprotective agents
    • Y.K. Gupta, M. Sharma, and G. Chaudhary Pyrogallol-induced hepatotoxicity in rats: a model to evaluate antioxidant hepatoprotective agents Methods Find. Exp. Clin. Pharmacol. 24 2002 497 500
    • (2002) Methods Find. Exp. Clin. Pharmacol. , vol.24 , pp. 497-500
    • Gupta, Y.K.1    Sharma, M.2    Chaudhary, G.3
  • 18
    • 33845649880 scopus 로고    scopus 로고
    • Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection
    • D. Grotto, L.D. Santa Maria, S. Boeira, J. Valentini, M.F. Charao, A.M. Moro, and et al. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection J. Pharm. Biomed. Anal. 43 2007 619 624
    • (2007) J. Pharm. Biomed. Anal. , vol.43 , pp. 619-624
    • Grotto, D.1    Santa Maria, L.D.2    Boeira, S.3    Valentini, J.4    Charao, M.F.5    Moro, A.M.6
  • 19
    • 0031569336 scopus 로고    scopus 로고
    • An isocratic assay for norepinephrine, dopamine, and 5-hydroxytryptamine using their native fluorescence by high-performance liquid chromatography with fluorescence detection in discrete brain areas of rat
    • M.K. Lakshmana, and T.R. Raju An isocratic assay for norepinephrine, dopamine, and 5-hydroxytryptamine using their native fluorescence by high-performance liquid chromatography with fluorescence detection in discrete brain areas of rat Anal. Biochem. 246 1997 166 170
    • (1997) Anal. Biochem. , vol.246 , pp. 166-170
    • Lakshmana, M.K.1    Raju, T.R.2
  • 20
    • 0031573408 scopus 로고    scopus 로고
    • A one-step fluorometric method for the continuous measurement of monoamine oxidase activity
    • M. Zhou, and N. Panchuk-Voloshina A one-step fluorometric method for the continuous measurement of monoamine oxidase activity Anal. Biochem. 253 1997 169 174
    • (1997) Anal. Biochem. , vol.253 , pp. 169-174
    • Zhou, M.1    Panchuk-Voloshina, N.2
  • 21
    • 84862775750 scopus 로고    scopus 로고
    • Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice
    • J.P. Jacobsen, W.B. Siesser, B.D. Sachs, S. Peterson, M.J. Cools, V. Setola, and et al. Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice Mol. Psychiatry 17 2012 694 704
    • (2012) Mol. Psychiatry , vol.17 , pp. 694-704
    • Jacobsen, J.P.1    Siesser, W.B.2    Sachs, B.D.3    Peterson, S.4    Cools, M.J.5    Setola, V.6
  • 22
    • 84859928064 scopus 로고    scopus 로고
    • Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: Role of GSK3beta and mitochondrial function
    • Y. Zhang, S.A. Babcock, N. Hu, J.R. Maris, H. Wang, and J. Ren Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3beta and mitochondrial function BMC Med. 10 2012 40
    • (2012) BMC Med. , vol.10 , pp. 40
    • Zhang, Y.1    Babcock, S.A.2    Hu, N.3    Maris, J.R.4    Wang, H.5    Ren, J.6
  • 23
    • 48849086702 scopus 로고    scopus 로고
    • Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart
    • G. Zhou, X. Li, D.W. Hein, X. Xiang, J.P. Marshall, S.D. Prabhu, and et al. Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart J. Am. Coll. Cardiol. 52 2008 655 666
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 655-666
    • Zhou, G.1    Li, X.2    Hein, D.W.3    Xiang, X.4    Marshall, J.P.5    Prabhu, S.D.6
  • 24
    • 0036267006 scopus 로고    scopus 로고
    • Hyperglycemia-induced apoptosis in mouse myocardium: Mitochondrial cytochrome C-mediated caspase-3 activation pathway
    • L. Cai, W. Li, G. Wang, L. Guo, Y. Jiang, and Y.J. Kang Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway Diabetes 51 2002 1938 1948
    • (2002) Diabetes , vol.51 , pp. 1938-1948
    • Cai, L.1    Li, W.2    Wang, G.3    Guo, L.4    Jiang, Y.5    Kang, Y.J.6
  • 25
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • J.C. Reed Bcl-2 and the regulation of programmed cell death J. Cell Biol. 124 1994 1 6
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 26
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • R.M. Kluck, E. Bossy-Wetzel, D.R. Green, and D.D. Newmeyer The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132 1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 27
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • J. Yang, X. Liu, K. Bhalla, C.N. Kim, A.M. Ibrado, J. Cai, and et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6
  • 28
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • D.R. Green, and J.C. Reed Mitochondria and apoptosis Science 281 1998 1309 1312
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 29
    • 0035749812 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiomyopathy: A brief review
    • L. Cai, and Y.J. Kang Oxidative stress and diabetic cardiomyopathy: a brief review Cardiovasc. Toxicol. 1 2001 181 193
    • (2001) Cardiovasc. Toxicol. , vol.1 , pp. 181-193
    • Cai, L.1    Kang, Y.J.2
  • 30
    • 84919788547 scopus 로고    scopus 로고
    • Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy
    • Z.V. Varga, Z. Giricz, L. Liaudet, G. Hasko, P. Ferdinandy, and P. Pacher Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy Biochim. Biophys. Acta 1852 2015 232 242
    • (2015) Biochim. Biophys. Acta , vol.1852 , pp. 232-242
    • Varga, Z.V.1    Giricz, Z.2    Liaudet, L.3    Hasko, G.4    Ferdinandy, P.5    Pacher, P.6
  • 31
    • 0028304920 scopus 로고
    • Which left ventricular function is impaired earlier in the evolution of diabetic cardiomyopathy? An echocardiographic study of young type i diabetic patients
    • D.C. Raev Which left ventricular function is impaired earlier in the evolution of diabetic cardiomyopathy? An echocardiographic study of young type I diabetic patients Diabetes Care 17 1994 633 639
    • (1994) Diabetes Care , vol.17 , pp. 633-639
    • Raev, D.C.1
  • 32
    • 0036435481 scopus 로고    scopus 로고
    • Left ventricular diastolic dysfunction as an early manifestation of diabetic cardiomyopathy
    • C.M. Schannwell, M. Schneppenheim, S. Perings, G. Plehn, and B.E. Strauer Left ventricular diastolic dysfunction as an early manifestation of diabetic cardiomyopathy Cardiology 98 2002 33 39
    • (2002) Cardiology , vol.98 , pp. 33-39
    • Schannwell, C.M.1    Schneppenheim, M.2    Perings, S.3    Plehn, G.4    Strauer, B.E.5
  • 34
    • 23944457569 scopus 로고    scopus 로고
    • Validation of echocardiographic and Doppler indexes of left ventricular relaxation in adult hypertensive and normotensive rats
    • M. Slama, J. Ahn, M. Peltier, J. Maizel, D. Chemla, J. Varagic, and et al. Validation of echocardiographic and Doppler indexes of left ventricular relaxation in adult hypertensive and normotensive rats Am. J. Physiol. Heart Circ. Physiol 289 2005 H1131 H1136
    • (2005) Am. J. Physiol. Heart Circ. Physiol , vol.289 , pp. H1131-H1136
    • Slama, M.1    Ahn, J.2    Peltier, M.3    Maizel, J.4    Chemla, D.5    Varagic, J.6
  • 35
    • 0021669339 scopus 로고
    • Protective effects of cardioplegia on diastolic function of hypertrophied rat hearts after hypothermic ischaemic arrest
    • C. Grousset, P. Menasche, C.S. Apstein, C. Mouas, F. Marotte, and A. Piwnica Protective effects of cardioplegia on diastolic function of hypertrophied rat hearts after hypothermic ischaemic arrest Eur. Heart J. 5 Suppl. F 1984 347 353
    • (1984) Eur. Heart J. , vol.5 , pp. 347-353
    • Grousset, C.1    Menasche, P.2    Apstein, C.S.3    Mouas, C.4    Marotte, F.5    Piwnica, A.6
  • 36
    • 1942484870 scopus 로고    scopus 로고
    • Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway
    • T. Ogata, T. Miyauchi, S. Sakai, M. Takanashi, Y. Irukayama-Tomobe, and I. Yamaguchi Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway J. Am. Coll. Cardiol. 43 2004 1481 1488
    • (2004) J. Am. Coll. Cardiol. , vol.43 , pp. 1481-1488
    • Ogata, T.1    Miyauchi, T.2    Sakai, S.3    Takanashi, M.4    Irukayama-Tomobe, Y.5    Yamaguchi, I.6
  • 37
    • 0034003574 scopus 로고    scopus 로고
    • Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model
    • K. Mizushige, L. Yao, T. Noma, H. Kiyomoto, Y. Yu, N. Hosomi, K. Ohmori, and H. Matsuo Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model Circulation 101 2000 899 907
    • (2000) Circulation , vol.101 , pp. 899-907
    • Mizushige, K.1    Yao, L.2    Noma, T.3    Kiyomoto, H.4    Yu, Y.5    Hosomi, N.6    Ohmori, K.7    Matsuo, H.8
  • 38
    • 70350224125 scopus 로고    scopus 로고
    • The ECG in diabetes mellitus
    • S. Stern, and S. Sclarowsky The ECG in diabetes mellitus Circulation 120 2009 1633 1636
    • (2009) Circulation , vol.120 , pp. 1633-1636
    • Stern, S.1    Sclarowsky, S.2
  • 39
    • 14944360931 scopus 로고    scopus 로고
    • Short-term effects of streptozotocin-induced diabetes on the electrocardiogram, physical activity and body temperature in rats
    • F.C. Howarth, M. Jacobson, O. Naseer, and E. Adeghate Short-term effects of streptozotocin-induced diabetes on the electrocardiogram, physical activity and body temperature in rats Exp. Physiol. 90 2005 237 245
    • (2005) Exp. Physiol. , vol.90 , pp. 237-245
    • Howarth, F.C.1    Jacobson, M.2    Naseer, O.3    Adeghate, E.4
  • 40
    • 0033855233 scopus 로고    scopus 로고
    • QTc interval length and QT dispersion as predictors of mortality in patients with non-insulin-dependent diabetes
    • P.K. Christensen, M.A. Gall, A. Major-Pedersen, A. Sato, P. Rossing, L. Breum, and et al. QTc interval length and QT dispersion as predictors of mortality in patients with non-insulin-dependent diabetes Scand. J. Clin. Lab. Invest. 60 2000 323 332
    • (2000) Scand. J. Clin. Lab. Invest. , vol.60 , pp. 323-332
    • Christensen, P.K.1    Gall, M.A.2    Major-Pedersen, A.3    Sato, A.4    Rossing, P.5    Breum, L.6
  • 41
    • 0041416156 scopus 로고    scopus 로고
    • QTc interval prolongation is a predictor of future strokes in patients with type 2 diabetes mellitus
    • C.R. Cardoso, G.F. Salles, and W. Deccache QTc interval prolongation is a predictor of future strokes in patients with type 2 diabetes mellitus Stroke 34 2003 2187 2194
    • (2003) Stroke , vol.34 , pp. 2187-2194
    • Cardoso, C.R.1    Salles, G.F.2    Deccache, W.3
  • 42
    • 84908505212 scopus 로고    scopus 로고
    • L-Glutamine supplementation prevents the development of experimental diabetic cardiomyopathy in streptozotocin-nicotinamide induced diabetic rats
    • S.L. Badole, G.B. Jangam, S.M. Chaudhari, A.E. Ghule, and A.A. Zanwar L-Glutamine supplementation prevents the development of experimental diabetic cardiomyopathy in streptozotocin-nicotinamide induced diabetic rats PLoS One 9 2014 e92697
    • (2014) PLoS One , vol.9 , pp. e92697
    • Badole, S.L.1    Jangam, G.B.2    Chaudhari, S.M.3    Ghule, A.E.4    Zanwar, A.A.5


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