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Volumn 36, Issue 4, 2015, Pages 957-966

Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a

Author keywords

Butein; Cisplatin; Extracellular signal regulated kinases; Forkhead box O3; P38 kinases; Protein kinase B

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BUTEIN; CISPLATIN; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P27; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1; CHALCONE DERIVATIVE; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN;

EID: 84940368287     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2324     Document Type: Article
Times cited : (53)

References (48)
  • 1
    • 78650893647 scopus 로고    scopus 로고
    • Cellular responses to cisplatin-induced DNA damage
    • Basu A and Krishnamurthy S: Cellular responses to cisplatin-induced DNA damage. J Nuleic Acids 2010: Article ID 201367, 2010.
    • (2010) J Nuleic Acids
    • Basu, A.1    Krishnamurthy, S.2
  • 2
    • 34247130456 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance
    • Brozovic A and Osmak M: Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance. Cancer Lett 251: 1-16, 2007.
    • (2007) Cancer Lett , vol.251 , pp. 1-16
    • Brozovic, A.1    Osmak, M.2
  • 3
    • 84893023460 scopus 로고    scopus 로고
    • Small ribosomal protein subunit S7 suppresses ovarian tumorigenesis through regulation of the PI3K/AKT and MAPK pathways
    • Wang Z, Hou J, Lu L, Qi Z, Sun J, Gao W, Meng J, Wang Y, Sun H, Gu H, et al: Small ribosomal protein subunit S7 suppresses ovarian tumorigenesis through regulation of the PI3K/AKT and MAPK pathways. PLoS One 8: e79117, 2013.
    • (2013) PLoS One , vol.8 , pp. e79117
    • Wang, Z.1    Hou, J.2    Lu, L.3    Qi, Z.4    Sun, J.5    Gao, W.6    Meng, J.7    Wang, Y.8    Sun, H.9    Gu, H.10
  • 4
    • 14844303304 scopus 로고    scopus 로고
    • Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization
    • Bava SV, Puliappadamba VT, Deepti A, Nair A, Karunagaran D and Anto RJ: Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization. J Biol Chem 280: 6301-6308, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 6301-6308
    • Bava, S.V.1    Puliappadamba, V.T.2    Deepti, A.3    Nair, A.4    Karunagaran, D.5    Anto, R.J.6
  • 6
    • 17444362645 scopus 로고    scopus 로고
    • The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase
    • Wang Y, Chan FL, Chen S and Leung LK: The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. Life Sci 77: 39-51, 2005.
    • (2005) Life Sci , vol.77 , pp. 39-51
    • Wang, Y.1    Chan, F.L.2    Chen, S.3    Leung, L.K.4
  • 7
    • 84903278774 scopus 로고    scopus 로고
    • Butein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen species
    • Cho SG, Woo SM and Ko SG: Butein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen species. J Exp Clin Cancer Res 33: 51, 2014.
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 51
    • Cho, S.G.1    Woo, S.M.2    Ko, S.G.3
  • 8
    • 0028336781 scopus 로고
    • Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation
    • Yit CC and Das NP: Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation. Cancer Lett 82: 65-72, 1994.
    • (1994) Cancer Lett , vol.82 , pp. 65-72
    • Yit, C.C.1    Das, N.P.2
  • 9
    • 80051750075 scopus 로고    scopus 로고
    • Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, p38, and uPA signaling multiple pathways
    • Ma CY, Ji WT, Chueh FS, Yang JS, Chen PY, Yu CC and Chung JG: Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, p38, and uPA signaling multiple pathways. J Agric Food Chem 59: 9032-9038, 2011.
    • (2011) J Agric Food Chem , vol.59 , pp. 9032-9038
    • Ma, C.Y.1    Ji, W.T.2    Chueh, F.S.3    Yang, J.S.4    Chen, P.Y.5    Yu, C.C.6    Chung, J.G.7
  • 10
    • 44449141072 scopus 로고    scopus 로고
    • A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells
    • Zhang L, Chen W and Li X: A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells. FEBS Lett 582: 1821-1828, 2008.
    • (2008) FEBS Lett , vol.582 , pp. 1821-1828
    • Zhang, L.1    Chen, W.2    Li, X.3
  • 11
    • 77957752821 scopus 로고    scopus 로고
    • Butein downregulates phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in cancerous and non-cancerous breast cells
    • Lau GT, Huang H, Lin SM and Leung LK: Butein downregulates phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in cancerous and non-cancerous breast cells. Eur J Pharmacol 648: 24-30, 2010.
    • (2010) Eur J Pharmacol , vol.648 , pp. 24-30
    • Lau, G.T.1    Huang, H.2    Lin, S.M.3    Leung, L.K.4
  • 12
    • 84859860480 scopus 로고    scopus 로고
    • Butein induces apoptosis and inhibits prostate tumor growth in vitro and in vivo
    • Khan N, Adhami VM, Afaq F and Mukhtar H: Butein induces apoptosis and inhibits prostate tumor growth in vitro and in vivo. Antioxid Redox Signal 16: 1195-1204, 2012.
    • (2012) Antioxid Redox Signal , vol.16 , pp. 1195-1204
    • Khan, N.1    Adhami, V.M.2    Afaq, F.3    Mukhtar, H.4
  • 13
    • 0442325056 scopus 로고    scopus 로고
    • About the evaluation of drug combination
    • Jin ZJ: About the evaluation of drug combination. Acta Pharmacol Sin 25: 146-147, 2004.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 146-147
    • Jin, Z.J.1
  • 14
    • 74849131331 scopus 로고    scopus 로고
    • Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation
    • Moon DO, Kim MO, Choi YH, Hyun JW, Chang WY and Kim GY: Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation. Cancer Lett 288: 204-213, 2010.
    • (2010) Cancer Lett , vol.288 , pp. 204-213
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Hyun, J.W.4    Chang, W.Y.5    Kim, G.Y.6
  • 16
    • 77952373274 scopus 로고    scopus 로고
    • FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1
    • Khatri S, Yepiskoposyan H, Gallo CA, Tandon P and Plas DR: FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. J Biol Chem 285: 15960-15965, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 15960-15965
    • Khatri, S.1    Yepiskoposyan, H.2    Gallo, C.A.3    Tandon, P.4    Plas, D.R.5
  • 18
    • 84893131728 scopus 로고    scopus 로고
    • Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38 modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A
    • Germani A, Matrone A, Grossi V, Peserico A, Sanese P, Liuzzi M, Palermo R, Murzilli S, Campese AF, Ingravallo G, et al: Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38? modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A. Cancer Lett 344: 110-118, 2014.
    • (2014) Cancer Lett , vol.344 , pp. 110-118
    • Germani, A.1    Matrone, A.2    Grossi, V.3    Peserico, A.4    Sanese, P.5    Liuzzi, M.6    Palermo, R.7    Murzilli, S.8    Campese, A.F.9    Ingravallo, G.10
  • 19
    • 84897547904 scopus 로고    scopus 로고
    • Sensitization of melanoma cells for TRAIL-induced apoptosis by activation of mitochondrialpathways via Bax
    • Quast SA, Berger A, Plötz M and Eberle J: Sensitization of melanoma cells for TRAIL-induced apoptosis by activation of mitochondrialpathways via Bax. Eur J Cell Biol 93: 42-48, 2014.
    • (2014) Eur J Cell Biol , vol.93 , pp. 42-48
    • Quast, S.A.1    Berger, A.2    Plötz, M.3    Eberle, J.4
  • 20
    • 84883450356 scopus 로고    scopus 로고
    • Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction
    • Kim MJ, Yun HS, Hong EH, Lee SJ, Baek JH, Lee CW, Yim JH, Kim JS, Park JK, Um HD and Hwang SG: Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction. Cancer Lett 339: 15-24, 2013.
    • (2013) Cancer Lett , vol.339 , pp. 15-24
    • Kim, M.J.1    Yun, H.S.2    Hong, E.H.3    Lee, S.J.4    Baek, J.H.5    Lee, C.W.6    Yim, J.H.7    Kim, J.S.8    Park, J.K.9    Um, H.D.10    Hwang, S.G.11
  • 21
    • 84893701178 scopus 로고    scopus 로고
    • Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation
    • Hsu HH, Cheng LH, Ho TJ, Kuo WW, Lin YM, Chen MC, Lee NH, Tsai FJ, Tsai KH and Huang CY: Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation. Tumour Biol 35: 303-313, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 303-313
    • Hsu, H.H.1    Cheng, L.H.2    Ho, T.J.3    Kuo, W.W.4    Lin, Y.M.5    Chen, M.C.6    Lee, N.H.7    Tsai, F.J.8    Tsai, K.H.9    Huang, C.Y.10
  • 22
    • 0032949934 scopus 로고    scopus 로고
    • Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: Inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
    • Persons DL, Yazlovitskaya EM, Cui W and Pelling JC: Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: Inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin Cancer Res 5: 1007-1014, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 1007-1014
    • Persons, D.L.1    Yazlovitskaya, E.M.2    Cui, W.3    Pelling, J.C.4
  • 23
    • 79959334667 scopus 로고    scopus 로고
    • Bim protein degradation contributes to cisplatin resistance
    • Wang J, Zhou JY and Wu GS: Bim protein degradation contributes to cisplatin resistance. J Biol Chem 286: 22384-22392, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 22384-22392
    • Wang, J.1    Zhou, J.Y.2    Wu, G.S.3
  • 24
    • 0034671751 scopus 로고    scopus 로고
    • Requirement for ERK activation in cisplatin-induced apoptosis
    • Wang X, Martindale JL and Holbrook NJ: Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem 275: 39435-39443, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 39435-39443
    • Wang, X.1    Martindale, J.L.2    Holbrook, N.J.3
  • 25
    • 80053931057 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin
    • Wang X, Govind S, Sajankila SP, Mi L, Roy R and Chung FL: Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin. Mol Nutr Food Res 55: 1572-1581, 2011.
    • (2011) Mol Nutr Food Res , vol.55 , pp. 1572-1581
    • Wang, X.1    Govind, S.2    Sajankila, S.P.3    Mi, L.4    Roy, R.5    Chung, F.L.6
  • 26
    • 78649991678 scopus 로고    scopus 로고
    • An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs
    • Sheridan C, Brumatti G, Elgendy M, Brunet M and Martin SJ: An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs. Oncogene 29: 6428-6441, 2010.
    • (2010) Oncogene , vol.29 , pp. 6428-6441
    • Sheridan, C.1    Brumatti, G.2    Elgendy, M.3    Brunet, M.4    Martin, S.J.5
  • 27
    • 84872141798 scopus 로고    scopus 로고
    • MAPK signaling in cisplatin-induced death: Predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells
    • Guégan JP, Ezan F, Théret N, Langouët S and Baffet G: MAPK signaling in cisplatin-induced death: Predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells. Carcinogenesis 34: 38-47, 2013.
    • (2013) Carcinogenesis , vol.34 , pp. 38-47
    • Guégan, J.P.1    Ezan, F.2    Théret, N.3    Langouët, S.4    Baffet, G.5
  • 28
    • 84904254716 scopus 로고    scopus 로고
    • Metformin inhibits the proliferation of A549/CDDP cells by activating p38 mitogen-activated protein kinase
    • Wang Y, Lin B, Wu J, Zhang H and Wu B: Metformin inhibits the proliferation of A549/CDDP cells by activating p38 mitogen-activated protein kinase. Oncol Lett 8: 1269-1274, 2014.
    • (2014) Oncol Lett , vol.8 , pp. 1269-1274
    • Wang, Y.1    Lin, B.2    Wu, J.3    Zhang, H.4    Wu, B.5
  • 29
    • 84887033367 scopus 로고    scopus 로고
    • Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
    • Pereira L, Igea A, Canovas B, Dolado I and Nebreda AR: Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. EMBO Mol Med 5: 1759-1774, 2013.
    • (2013) EMBO Mol Med , vol.5 , pp. 1759-1774
    • Pereira, L.1    Igea, A.2    Canovas, B.3    Dolado, I.4    Nebreda, A.R.5
  • 30
    • 79952439364 scopus 로고    scopus 로고
    • Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK
    • Feng R, Zhai WL, Yang HY, Jin H and Zhang QX: Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK. Biochem Biophys Res Commun 406: 299-304, 2011.
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 299-304
    • Feng, R.1    Zhai, W.L.2    Yang, H.Y.3    Jin, H.4    Zhang, Q.X.5
  • 32
    • 84869880809 scopus 로고    scopus 로고
    • Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma
    • Wang SN, Lee KT, Tsai CJ, Chen YJ and Yeh YT: Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma. Eur J Clin Invest 42: 1295-1301, 2012.
    • (2012) Eur J Clin Invest , vol.42 , pp. 1295-1301
    • Wang, S.N.1    Lee, K.T.2    Tsai, C.J.3    Chen, Y.J.4    Yeh, Y.T.5
  • 33
  • 34
    • 84893176326 scopus 로고    scopus 로고
    • P38 negatively regulates survival and malignant selection of transformed bronchioalveolar stem cells
    • Voisset E, Oeztuerk-Winder F, Ruiz EJ and Ventura JJ: p38? negatively regulates survival and malignant selection of transformed bronchioalveolar stem cells. PLoS One 8: e78911, 2013.
    • (2013) PLoS One , vol.8 , pp. e78911
    • Voisset, E.1    Oeztuerk-Winder, F.2    Ruiz, E.J.3    Ventura, J.J.4
  • 36
    • 84907468386 scopus 로고    scopus 로고
    • FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression
    • Ishitsuka A, Fujine E, Mizutani Y, Tawada C, Kanoh H, Banno Y and Seishima M: FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. Int J Mol Med 34: 1169-1174, 2014.
    • (2014) Int J Mol Med , vol.34 , pp. 1169-1174
    • Ishitsuka, A.1    Fujine, E.2    Mizutani, Y.3    Tawada, C.4    Kanoh, H.5    Banno, Y.6    Seishima, M.7
  • 37
    • 0032562682 scopus 로고    scopus 로고
    • The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway
    • Berra E, Diaz-Meco MT and Moscat J: The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway. J Biol Chem 273: 10792-10797, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 10792-10797
    • Berra, E.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 42
    • 70349644002 scopus 로고    scopus 로고
    • Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
    • Chiacchiera F and Simone C: Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism. Autophagy 5: 1030-1033, 2009.
    • (2009) Autophagy , vol.5 , pp. 1030-1033
    • Chiacchiera, F.1    Simone, C.2
  • 44
    • 41849108086 scopus 로고    scopus 로고
    • Many forks in the path: Cycling with FoxO
    • Ho KK, Myatt SS and Lam EW: Many forks in the path: Cycling with FoxO. Oncogene 27: 2300-2311, 2008.
    • (2008) Oncogene , vol.27 , pp. 2300-2311
    • Ho, K.K.1    Myatt, S.S.2    Lam, E.W.3
  • 46
    • 9244239811 scopus 로고    scopus 로고
    • G1 cell-cycle control and cancer
    • Massagué J: G1 cell-cycle control and cancer. Nature 432: 298-306, 2004.
    • (2004) Nature , vol.432 , pp. 298-306
    • Massagué, J.1
  • 47
    • 84888419560 scopus 로고    scopus 로고
    • Estrogen receptor isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12
    • Lee MT, Ho SM, Tarapore P, Chung I and Leung YK: Estrogen receptor ? isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12. Neoplasia 15: 1262-1271, 2013.
    • (2013) Neoplasia , vol.15 , pp. 1262-1271
    • Lee, M.T.1    Ho, S.M.2    Tarapore, P.3    Chung, I.4    Leung, Y.K.5
  • 48
    • 84894281739 scopus 로고    scopus 로고
    • Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression
    • Kiyoshima T1, Yoshida H, Wada H, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H and Sakai H: Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression. PLoS One 8: e80998, 2013.
    • (2013) PLoS One , vol.8 , pp. e80998
    • Kiyoshima, T.1    Yoshida, H.2    Wada, H.3    Nagata, K.4    Fujiwara, H.5    Kihara, M.6    Hasegawa, K.7    Someya, H.8    Sakai, H.9


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