Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome

Annals of the Rheumatic Diseases

Volumn 75, Issue 6, 2016, Pages 1236-1245

  Cumpelik, Arun ^a   Ankli, Barbara ^a   Zecher, Daniel ^a,b   Schifferli, Jürg A ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; MERTK PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; URATE; CYTOKINE; LIPOSOME; PHOSPHATIDYLSERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ORGANELLE; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ACTIVITY; DISEASE ASSOCIATION; ECTOSOME; GOUT; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE MICROPARTICLE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL MICROVESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; ACUTE DISEASE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; HUMAN; IMMUNOLOGY; LEUKOCYTE ACTIVATION; METABOLISM; NEUTROPHIL; PATHOLOGY; PERITONITIS; PHYSIOLOGY; TRANSPLANTATION;

ACUTE DISEASE; ANIMALS; CELL-DERIVED MICROPARTICLES; CELLS, CULTURED; COMPLEMENT C5A; CYTOKINES; GOUT; HUMANS; INFLAMMASOMES; LIPOSOMES; MICE, INBRED C57BL; NEUTROPHIL ACTIVATION; NEUTROPHIL INFILTRATION; NEUTROPHILS; PERITONITIS; PHOSPHATIDYLSERINES;

EID: 84940192911     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2015-207338     Document Type: Article

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