메뉴 건너뛰기




Volumn 67, Issue 9, 2015, Pages 2283-2291

Perspectives from masters in rheumatology and autoimmunity: Can we get closer to a cure for rheumatoid arthritis?

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ANTIRHEUMATIC AGENT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INFLIXIMAB; INTERLEUKIN 17; INTERLEUKIN 6; METHOTREXATE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY; TUMOR NECROSIS FACTOR INHIBITOR; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 84940105149     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39269     Document Type: Review
Times cited : (48)

References (60)
  • 1
    • 0024538157 scopus 로고
    • Factors predicting a poor life prognosis in rheumatoid arthritis: An eight year prospective study
    • Erhardt CC, Mumford PA, Venables PJ, Maini RN., Factors predicting a poor life prognosis in rheumatoid arthritis: an eight year prospective study. Ann Rheum Dis 1989; 48: 7-13.
    • (1989) Ann Rheum Dis , vol.48 , pp. 7-13
    • Erhardt, C.C.1    Mumford, P.A.2    Venables, P.J.3    Maini, R.N.4
  • 2
    • 0026320206 scopus 로고
    • The efficacy and safety of low-dose corticosteroids for rheumatoid arthritis
    • Caldwell JR, Furst DE., The efficacy and safety of low-dose corticosteroids for rheumatoid arthritis. Semin Arthritis Rheum 1991; 21: 1-11.
    • (1991) Semin Arthritis Rheum , vol.21 , pp. 1-11
    • Caldwell, J.R.1    Furst, D.E.2
  • 5
    • 0142041982 scopus 로고    scopus 로고
    • TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
    • Feldmann M, Maini RN., TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. Nat Med 2003; 9: 1245-50.
    • (2003) Nat Med , vol.9 , pp. 1245-1250
    • Feldmann, M.1    Maini, R.N.2
  • 6
    • 0029044362 scopus 로고
    • American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis
    • Felson DT, Anderson JJ, Boers M, Bombardier C, Furst D, Goldsmith C, et al., American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995; 38: 727-35.
    • (1995) Arthritis Rheum , vol.38 , pp. 727-735
    • Felson, D.T.1    Anderson, J.J.2    Boers, M.3    Bombardier, C.4    Furst, D.5    Goldsmith, C.6
  • 7
    • 0028815803 scopus 로고
    • Modified disease activity scores that include twenty-eight-joint counts: Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
    • Prevoo ML, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL., Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-8.
    • (1995) Arthritis Rheum , vol.38 , pp. 44-48
    • Prevoo, M.L.1    Van't Hof, M.A.2    Kuper, H.H.3    Van Leeuwen, M.A.4    Van De Putte, L.B.5    Van Riel, P.L.6
  • 8
    • 84871033136 scopus 로고    scopus 로고
    • Forget personalised medicine and focus on abating disease activity
    • Smolen JS, Aletaha, D., Forget personalised medicine and focus on abating disease activity. Ann Rheum Dis 2013; 72: 3-6.
    • (2013) Ann Rheum Dis , vol.72 , pp. 3-6
    • Smolen, J.S.1    Aletaha, D.2
  • 9
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart failure: Results of the Anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
    • Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT., Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart failure: results of the Anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation 2003; 107: 3133-40.
    • (2003) Circulation , vol.107 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 10
    • 85056679322 scopus 로고    scopus 로고
    • Smolen J.S. Lipsky P.E. editors. Boca Raton (FL): CRC Press
    • Smolen JS, Lipsky PE, editors. Contemporary targeted therapies in rheumatology. Boca Raton (FL): CRC Press; 2007.
    • (2007) Contemporary Targeted Therapies in Rheumatology
  • 11
    • 79955563297 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis
    • Genovese MC, Cohen SB, Wofsy D, Weinblatt ME, Firestein GS, Brahn E, et al., A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis. J Rheumatol 2011; 38: 846-54.
    • (2011) J Rheumatol , vol.38 , pp. 846-854
    • Genovese, M.C.1    Cohen, S.B.2    Wofsy, D.3    Weinblatt, M.E.4    Firestein, G.S.5    Brahn, E.6
  • 12
    • 84934317552 scopus 로고    scopus 로고
    • The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
    • Boyle DL, Soma K, Hodge J, Kavanaugh A, Mandel D, Mease P, et al., The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis. Ann Rheum Dis 2015; 74: 1311-6.
    • (2015) Ann Rheum Dis , vol.74 , pp. 1311-1316
    • Boyle, D.L.1    Soma, K.2    Hodge, J.3    Kavanaugh, A.4    Mandel, D.5    Mease, P.6
  • 13
    • 84877603562 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in patients with rheumatoid arthritis: A phase II, dose-finding, double-blind, randomised, placebo controlled study
    • Genovese MC, Durez P, Richards HB, Supronik J, Dokoupilova E, Mazurov V, et al., Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study. Ann Rheum Dis 2013; 72: 863-9.
    • (2013) Ann Rheum Dis , vol.72 , pp. 863-869
    • Genovese, M.C.1    Durez, P.2    Richards, H.B.3    Supronik, J.4    Dokoupilova, E.5    Mazurov, V.6
  • 14
    • 84888399058 scopus 로고    scopus 로고
    • Do people with HIV infection have a normal life expectancy in the era of combination antiretroviral therapy?
    • Sabin CA., Do people with HIV infection have a normal life expectancy in the era of combination antiretroviral therapy? BMC Med 2013; 11: 251.
    • (2013) BMC Med , vol.11 , pp. 251
    • Sabin, C.A.1
  • 15
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • Pui CH, Robison LL, Look AT., Acute lymphoblastic leukaemia. Lancet 2008; 271: 1030-43.
    • (2008) Lancet , vol.271 , pp. 1030-1043
    • Pui, C.H.1    Robison, L.L.2    Look, A.T.3
  • 16
    • 49349095724 scopus 로고    scopus 로고
    • Monoclonal antibody therapy for B-cell non-Hodgkin's lymphoma [review]
    • Cheson BD, Leonard JP., Monoclonal antibody therapy for B-cell non-Hodgkin's lymphoma [review]. N Engl J Med 2008; 359: 613-26.
    • (2008) N Engl J Med , vol.359 , pp. 613-626
    • Cheson, B.D.1    Leonard, J.P.2
  • 17
    • 0030751946 scopus 로고    scopus 로고
    • Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis
    • Boers M, Verhoeven AC, Markusse HM, van de Laar MA, Westhovens R, van Denderen JC, et al., Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 1997; 350: 309-18.
    • (1997) Lancet , vol.350 , pp. 309-318
    • Boers, M.1    Verhoeven, A.C.2    Markusse, H.M.3    Van De Laar, M.A.4    Westhovens, R.5    Van Denderen, J.C.6
  • 18
    • 0036096084 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: Results of a two-year, randomized, double-blind, placebo-controlled trial
    • O'Dell JR, Leff R, Paulsen G, Haire C, Mallek J, Eckhoff PJ, et al., Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: results of a two-year, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002; 46: 1164-70.
    • (2002) Arthritis Rheum , vol.46 , pp. 1164-1170
    • O'Dell, J.R.1    Leff, R.2    Paulsen, G.3    Haire, C.4    Mallek, J.5    Eckhoff, P.J.6
  • 19
    • 84893738246 scopus 로고    scopus 로고
    • Efficacy of conventional synthetic disease-modifying anti-rheumatic drugs, glucocorticoids and tofacitinib: A systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis
    • 5
    • Gaujoux-Viala C, Nam J, Ramiro S, Landewe R, Buch MH, Smolen JS, et al., Efficacy of conventional synthetic disease-modifying anti-rheumatic drugs, glucocorticoids and tofacitinib: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis. Ann Rheum Dis 2014; 73: 510-5.
    • (2014) Ann Rheum Dis , vol.73 , pp. 510
    • Gaujoux-Viala, C.1    Nam, J.2    Ramiro, S.3    Landewe, R.4    Buch, M.H.5    Smolen, J.S.6
  • 20
    • 0031660364 scopus 로고    scopus 로고
    • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
    • Maini RN, Breedveld FC, Kalden JR, Smolen JS, Davis D, Macfarlane JD, et al., Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998; 41: 1552-63.
    • (1998) Arthritis Rheum , vol.41 , pp. 1552-1563
    • Maini, R.N.1    Breedveld, F.C.2    Kalden, J.R.3    Smolen, J.S.4    Davis, D.5    MacFarlane, J.D.6
  • 21
    • 27744514865 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial
    • Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, van Zeben D, Kerstens PJ, Hazes JM, et al., Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum 2005; 52: 3381-90.
    • (2005) Arthritis Rheum , vol.52 , pp. 3381-3390
    • Goekoop-Ruiterman, Y.P.1    De Vries-Bouwstra, J.K.2    Allaart, C.F.3    Van Zeben, D.4    Kerstens, P.J.5    Hazes, J.M.6
  • 22
    • 2342551979 scopus 로고    scopus 로고
    • Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate
    • for the 20000223 Study Group
    • Genovese MC, Cohen S, Moreland L, Lium D, Robbins S, Newmark R, et al., for the 20000223 Study Group. Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate. Arthritis Rheum 2004; 50: 1412-9.
    • (2004) Arthritis Rheum , vol.50 , pp. 1412-1419
    • Genovese, M.C.1    Cohen, S.2    Moreland, L.3    Lium, D.4    Robbins, S.5    Newmark, R.6
  • 23
    • 33846853779 scopus 로고    scopus 로고
    • Selective co-stimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: A randomised clinical trial
    • Weinblatt M, Schiff M, Goldman A, Kremer J, Luggen M, Li T, et al., Selective co-stimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomised clinical trial. Ann Rheum Dis 2007; 66: 228-34.
    • (2007) Ann Rheum Dis , vol.66 , pp. 228-234
    • Weinblatt, M.1    Schiff, M.2    Goldman, A.3    Kremer, J.4    Luggen, M.5    Li, T.6
  • 24
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF., Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983-5.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 25
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N., Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989; 246: 1306-9.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 26
    • 0242319672 scopus 로고    scopus 로고
    • Adenoviral delivery of soluble VEGF receptor-1 (sFlt-1) abrogates disease activity in murine collagen-induced arthritis
    • Afuwape AO, Feldmann M, Paleolog EM., Adenoviral delivery of soluble VEGF receptor-1 (sFlt-1) abrogates disease activity in murine collagen-induced arthritis. Gene Ther 2003; 10: 1950-60.
    • (2003) Gene Ther , vol.10 , pp. 1950-1960
    • Afuwape, A.O.1    Feldmann, M.2    Paleolog, E.M.3
  • 27
    • 0038248703 scopus 로고    scopus 로고
    • The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis
    • Sumariwalla PF, Cao Y, Wu HL, Feldmann M, Paleolog EM., The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis. Arthritis Res Ther 2003; 5: R32-9.
    • (2003) Arthritis Res Ther , vol.5 , pp. R32-R39
    • Sumariwalla, P.F.1    Cao, Y.2    Wu, H.L.3    Feldmann, M.4    Paleolog, E.M.5
  • 28
    • 79953299484 scopus 로고    scopus 로고
    • Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction
    • Aletaha D, Funovits J, Smolen JS., Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction Ann Rheum Dis 2011; 70: 733-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 733-739
    • Aletaha, D.1    Funovits, J.2    Smolen, J.S.3
  • 29
    • 61649119071 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis
    • Miller MC, Manning HB, Jain A, Troeberg L, Dudhia J, Essex D, et al., Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis. Arthritis Rheum 2009; 60: 686-97.
    • (2009) Arthritis Rheum , vol.60 , pp. 686-697
    • Miller, M.C.1    Manning, H.B.2    Jain, A.3    Troeberg, L.4    Dudhia, J.5    Essex, D.6
  • 30
    • 84995586769 scopus 로고    scopus 로고
    • Selective inhibition of membrane type 1 matrix metalloproteinase abrogates progression of inflammatory arthritis: Synergy with TNF blockade
    • E-pub ahead of print
    • Kaneko K, Williams RO, Dransfield DT, Nixon AE, Sandison A, Itoh Y., Selective inhibition of membrane type 1 matrix metalloproteinase abrogates progression of inflammatory arthritis: synergy with TNF blockade. Arthritis Rheumatol 2015. E-pub ahead of print.
    • (2015) Arthritis Rheumatol
    • Kaneko, K.1    Williams, R.O.2    Dransfield, D.T.3    Nixon, A.E.4    Sandison, A.5    Itoh, Y.6
  • 32
    • 84870291587 scopus 로고    scopus 로고
    • Epigenetic contributions in the development of rheumatoid arthritis
    • Klein K, Ospelt C, Gay S., Epigenetic contributions in the development of rheumatoid arthritis. Arthritis Res Ther 2012; 14: 227.
    • (2012) Arthritis Res Ther , vol.14 , pp. 227
    • Klein, K.1    Ospelt, C.2    Gay, S.3
  • 34
    • 0037198427 scopus 로고    scopus 로고
    • Effects of insulin in relatives of patients with type 1 diabetes mellitus
    • Diabetes Prevention Trial-Type 1 Diabetes Study Group
    • Diabetes Prevention Trial-Type 1 Diabetes Study Group. Effects of insulin in relatives of patients with type 1 diabetes mellitus. N Engl J Med 2002; 346: 1685-91.
    • (2002) N Engl J Med , vol.346 , pp. 1685-1691
  • 35
    • 84878050627 scopus 로고    scopus 로고
    • Autoimmunity in rheumatoid arthritis: Citrulline immunity and beyond
    • Klareskog L, Lundberg K, Malmstrom V., Autoimmunity in rheumatoid arthritis: citrulline immunity and beyond. Adv Immunol 2013; 118: 129-58.
    • (2013) Adv Immunol , vol.118 , pp. 129-158
    • Klareskog, L.1    Lundberg, K.2    Malmstrom, V.3
  • 36
    • 0242720407 scopus 로고    scopus 로고
    • PAD, a growing family of citrullinating enzymes: Genes, features and involvement in disease
    • Vossenaar ER, Zendman AJ, van Venrooij WJ, Pruijn GJ., PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 2003; 25: 1106-18.
    • (2003) Bioessays , vol.25 , pp. 1106-1118
    • Vossenaar, E.R.1    Zendman, A.J.2    Van Venrooij, W.J.3    Pruijn, G.J.4
  • 37
    • 73249145617 scopus 로고    scopus 로고
    • Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis
    • Wegner N, Lundberg K, Kinloch A, Fisher B, Malmstrom V, Feldmann M, et al., Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis. Immunol Rev 2010; 233: 34-54.
    • (2010) Immunol Rev , vol.233 , pp. 34-54
    • Wegner, N.1    Lundberg, K.2    Kinloch, A.3    Fisher, B.4    Malmstrom, V.5    Feldmann, M.6
  • 38
    • 84873525758 scopus 로고    scopus 로고
    • Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis
    • Thomas R., Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis. Arthritis Res Ther 2013; 61: 553-60.
    • (2013) Arthritis Res Ther , vol.61 , pp. 553-560
    • Thomas, R.1
  • 39
    • 84930453993 scopus 로고    scopus 로고
    • Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients
    • Benham H, Nel HJ, Law SC, Mehdi AM, Street S, Ramnoruth N, et al., Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients. Sci Transl Med 2015; 7: 1-12.
    • (2015) Sci Transl Med , vol.7 , pp. 1-12
    • Benham, H.1    Nel, H.J.2    Law, S.C.3    Mehdi, A.M.4    Street, S.5    Ramnoruth, N.6
  • 40
    • 58149166804 scopus 로고    scopus 로고
    • Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
    • Notley CA, Inglis JJ, Alzabin S, McCann FE, McNamee KE, Williams RO., Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells. J Exp Med 2008; 205: 2491-7.
    • (2008) J Exp Med , vol.205 , pp. 2491-2497
    • Notley, C.A.1    Inglis, J.J.2    Alzabin, S.3    McCann, F.E.4    McNamee, K.E.5    Williams, R.O.6
  • 41
    • 84903478179 scopus 로고    scopus 로고
    • A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors
    • Genovese MC, Greenwald M, Cho CS, Berman A, Jin L, Cameron GS, et al., A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors. Arthritis Rheumatol 2014; 66: 1693-704.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1693-1704
    • Genovese, M.C.1    Greenwald, M.2    Cho, C.S.3    Berman, A.4    Jin, L.5    Cameron, G.S.6
  • 43
    • 79960883879 scopus 로고    scopus 로고
    • Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy
    • Chen DY, Chen YM, Chen HH, Hsieh CW, Lin CC, Lan JL., Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy. Arthritis Res Ther 2011; 13: R126.
    • (2011) Arthritis Res Ther , vol.13 , pp. R126
    • Chen, D.Y.1    Chen, Y.M.2    Chen, H.H.3    Hsieh, C.W.4    Lin, C.C.5    Lan, J.L.6
  • 44
    • 84866074216 scopus 로고    scopus 로고
    • Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway
    • Alzabin S, Abraham SM, Taher TE, Palfreeman A, Hull D, McNamee K, et al., Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway. Ann Rheum Dis 2012; 71: 1741-8.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1741-1748
    • Alzabin, S.1    Abraham, S.M.2    Taher, T.E.3    Palfreeman, A.4    Hull, D.5    McNamee, K.6
  • 45
    • 75649131191 scopus 로고    scopus 로고
    • Developments in the scientific understanding of rheumatoid arthritis
    • Goronzy JJ, Weyand CM., Developments in the scientific understanding of rheumatoid arthritis. Arthritis Res Ther 2009; 11: 249.
    • (2009) Arthritis Res Ther , vol.11 , pp. 249
    • Goronzy, J.J.1    Weyand, C.M.2
  • 47
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al., Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013; 369: 134-44.
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.S.4    Hwu, W.J.5    Kefford, R.6
  • 49
    • 77951158406 scopus 로고    scopus 로고
    • Protein kinase C-θ mediates negative feedback on regulatory T cell function
    • Zanin-Zhorov A, Ding Y, Kumari S, Attur M, Hippen KL, Brown M, et al., Protein kinase C-θ mediates negative feedback on regulatory T cell function. Science 2010; 328: 372-6.
    • (2010) Science , vol.328 , pp. 372-376
    • Zanin-Zhorov, A.1    Ding, Y.2    Kumari, S.3    Attur, M.4    Hippen, K.L.5    Brown, M.6
  • 50
    • 84887081136 scopus 로고    scopus 로고
    • Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
    • Sugiyama D, Nishikawa H, Maeda Y, Nishioka M, Tanemura A, Katayama I, et al., Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans. Proc Natl Acad Sci U S A 2013; 110: 17945-50.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 17945-17950
    • Sugiyama, D.1    Nishikawa, H.2    Maeda, Y.3    Nishioka, M.4    Tanemura, A.5    Katayama, I.6
  • 51
    • 84908365717 scopus 로고    scopus 로고
    • Selective tumor necrosis factor receptor i blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen-induced arthritis
    • McCann FE, Perocheau DP, Ruspi G, Blazek K, Davies ML, Feldmann M, et al., Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen-induced arthritis. Arthritis Rheumatol 2014; 66: 2728-38.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2728-2738
    • McCann, F.E.1    Perocheau, D.P.2    Ruspi, G.3    Blazek, K.4    Davies, M.L.5    Feldmann, M.6
  • 52
    • 84883238929 scopus 로고    scopus 로고
    • Selective blockade of tumor necrosis factor receptor i inhibits proinflammatory cytokine and chemokine production in human rheumatoid arthritis synovial membrane cell cultures
    • Schmidt EM, Davies M, Mistry P, Green P, Giddins G, Feldmann M, et al., Selective blockade of tumor necrosis factor receptor I inhibits proinflammatory cytokine and chemokine production in human rheumatoid arthritis synovial membrane cell cultures. Arthritis Rheum 2013; 65: 2262-73.
    • (2013) Arthritis Rheum , vol.65 , pp. 2262-2273
    • Schmidt, E.M.1    Davies, M.2    Mistry, P.3    Green, P.4    Giddins, G.5    Feldmann, M.6
  • 53
    • 78650677911 scopus 로고    scopus 로고
    • The need for personalised medicine for rheumatoid arthritis
    • Isaacs JD, Ferraccioli G., The need for personalised medicine for rheumatoid arthritis. Ann Rheum Dis 2011; 70: 4-7.
    • (2011) Ann Rheum Dis , vol.70 , pp. 4-7
    • Isaacs, J.D.1    Ferraccioli, G.2
  • 55
    • 84887323708 scopus 로고    scopus 로고
    • Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
    • Scher JU, Sczesnak A, Longman RS, Segata N, Ubeda C, Bielski C, et al., Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife 2013; 2: e01202.
    • (2013) Elife , vol.2 , pp. e01202
    • Scher, J.U.1    Sczesnak, A.2    Longman, R.S.3    Segata, N.4    Ubeda, C.5    Bielski, C.6
  • 56
    • 84864448111 scopus 로고    scopus 로고
    • High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
    • Mullokandov G, Baccarini A, Ruzo A, Jayaprakash AD, Tung N, Israelow B, et al., High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries. Nat Methods 2012; 9: 840-6.
    • (2012) Nat Methods , vol.9 , pp. 840-846
    • Mullokandov, G.1    Baccarini, A.2    Ruzo, A.3    Jayaprakash, A.D.4    Tung, N.5    Israelow, B.6
  • 57
    • 67651087321 scopus 로고    scopus 로고
    • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
    • Brown BD, Naldini L., Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat Rev Genet 2009; 10: 578-85.
    • (2009) Nat Rev Genet , vol.10 , pp. 578-585
    • Brown, B.D.1    Naldini, L.2
  • 58
    • 84895743899 scopus 로고    scopus 로고
    • Beyond antibodies: New affinity reagents to unlock the proteome
    • Lollo B, Steele F, Gold L., Beyond antibodies: new affinity reagents to unlock the proteome. Proteomics 2014; 14: 638-44.
    • (2014) Proteomics , vol.14 , pp. 638-644
    • Lollo, B.1    Steele, F.2    Gold, L.3
  • 59
    • 79955750055 scopus 로고    scopus 로고
    • Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
    • Bendall SC, Simonds EF, Qiu P, Amir ED, Krutzik PO, Finck R, et al., Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 2011; 332: 687-96.
    • (2011) Science , vol.332 , pp. 687-696
    • Bendall, S.C.1    Simonds, E.F.2    Qiu, P.3    Amir, E.D.4    Krutzik, P.O.5    Finck, R.6
  • 60
    • 79959795633 scopus 로고    scopus 로고
    • Discontinuation of infliximab and potential predictors of persistent low disease activity in patients with early rheumatoid arthritis and disease activity score-steered therapy: Subanalysis of the BeSt study
    • Van den Broek M, Klarenbeek NB, Dirven L, van Schaardenburg D, Hulsmans HM, Kerstens PJ, et al., Discontinuation of infliximab and potential predictors of persistent low disease activity in patients with early rheumatoid arthritis and disease activity score-steered therapy: subanalysis of the BeSt study. Ann Rheum Dis 2011; 70: 1389-94.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1389-1394
    • Van Den Broek, M.1    Klarenbeek, N.B.2    Dirven, L.3    Van Schaardenburg, D.4    Hulsmans, H.M.5    Kerstens, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.