A potent inhibitor of phosphoinositide 3-kinase (PI3K) and mitogen activated protein (MAP) kinase signalling, Quercetin (3, 3', 4', 5, 7-pentahydroxyflavone) promotes cell death in Ultraviolet (UV)-B-irradiated B16F10 melanoma cells

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Rafiq, Rather A ^a   Quadri, Afnan ^a   Nazir, Lone A ^a,b   Peerzada, Kaiser ^a   Ganai, Bashir A ^c   Tasduq, Sheikh A ^a,b  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^c UNIVERSITY OF KASHMIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; BIM PROTEIN; BIOFLAVONOID; CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; QUERCETIN(3, 3', 4',5, 7 PENTAHYDROXYFLAVONE); REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CALCIUM; QUERCETIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CANCER INHIBITION; CELL DEATH; CONTROLLED STUDY; DNA CLEAVAGE; ENZYME ACTIVATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MELANOMA CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ULTRAVIOLET B RADIATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CYCLE G1 PHASE; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; MELANOMA; METABOLISM; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CALCIUM; CASPASES; CELL DEATH; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; G1 PHASE; HUMANS; MELANOMA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; QUERCETIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 84940056573     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131253     Document Type: Article

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