-
1
-
-
84882754089
-
Computational approaches
-
Fadeel B, Pietroiusti A, Shvedova A A, (eds), Academic Press, London:
-
Epa, V. C.; Winkler, D. A.; Tran, L.; Fadeel, B.; Pietroiusti, A.; Shvedova, A. A. Computational approaches. In Adverse effects of engineered nanomaterials: Exposure, toxicology, and impact on human health; Fadeel, B.; Pietroiusti, A.; Shvedova, A. A., Eds.; Academic Press: London, 2012; pp 85–96.
-
(2012)
Adverse effects of engineered nanomaterials: Exposure, toxicology, and impact on human health
, pp. 85-96
-
-
Epa, V.C.1
Winkler, D.A.2
Tran, L.3
Fadeel, B.4
Pietroiusti, A.5
Shvedova, A.A.6
-
2
-
-
67650457089
-
Too small to overlook
-
Maynard, A.; Rejeski, D. Too small to overlook. Nature2009, 460, 174–174.
-
(2009)
Nature
, vol.460
, pp. 174
-
-
Maynard, A.1
Rejeski, D.2
-
3
-
-
31944451232
-
Toxic potential of materials at the nanolevel
-
Nel, A.; Xia, T.; Madler, L.; Li, N. Toxic potential of materials at the nanolevel. Science2006, 311, 622–627.
-
(2006)
Science
, vol.311
, pp. 622-627
-
-
Nel, A.1
Xia, T.2
Madler, L.3
Li, N.4
-
4
-
-
72949094881
-
In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles
-
Hartig, W.; Kacza, J.; Paulke, B. R.; Grosche, J.; Bauer, U.; Hoffmann, A.; Elsinghorst, P. W.; Gutschow, M. In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles. Euro. J. Neurosci.2010, 31, 99–109.
-
(2010)
Euro. J. Neurosci.
, vol.31
, pp. 99-109
-
-
Hartig, W.1
Kacza, J.2
Paulke, B.R.3
Grosche, J.4
Bauer, U.5
Hoffmann, A.6
Elsinghorst, P.W.7
Gutschow, M.8
-
5
-
-
84885757504
-
Applying quantitative structure-activity relationship approaches to nanotoxicology: Current status and future potential
-
Winkler, D. A.; Mombelli, E.; Pietroiusti, A.; Tran, L.; Worth, A.; Fadeel, B.; McCall, M. J. Applying quantitative structure-activity relationship approaches to nanotoxicology: Current status and future potential. Toxicology2013, 313, 15–23.
-
(2013)
Toxicology
, vol.313
, pp. 15-23
-
-
Winkler, D.A.1
Mombelli, E.2
Pietroiusti, A.3
Tran, L.4
Worth, A.5
Fadeel, B.6
McCall, M.J.7
-
6
-
-
66749166478
-
Functionalized carbon nanotubes specifically bind to α-chymotrypsin’s catalytic site and regulate its enzymatic function
-
Zhang, B.; Xing, Y. H.; Li, Z. W.; Zhou, H. Y.; Mu, Q. X.; Yan, B. Functionalized carbon nanotubes specifically bind to α-chymotrypsin’s catalytic site and regulate its enzymatic function. Nano Lett.2009, 9, 2280–2284.
-
(2009)
Nano Lett.
, vol.9
, pp. 2280-2284
-
-
Zhang, B.1
Xing, Y.H.2
Li, Z.W.3
Zhou, H.Y.4
Mu, Q.X.5
Yan, B.6
-
7
-
-
43149095577
-
A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response
-
Zhou, H. Y.; Mu, Q. X.; Gao, N. N.; Liu, A. F.; Xing, Y. H.; Gao, S. L.; Zhang, Q.; Qu, G. B.; Chen, Y. Y.; Liu, G. et al. A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response. Nano Lett.2008, 8, 859–865.
-
(2008)
Nano Lett.
, vol.8
, pp. 859-865
-
-
Zhou, H.Y.1
Mu, Q.X.2
Gao, N.N.3
Liu, A.F.4
Xing, Y.H.5
Gao, S.L.6
Zhang, Q.7
Qu, G.B.8
Chen, Y.Y.9
Liu, G.10
-
8
-
-
27944496941
-
Cell-specific targeting of nanoparticles by multivalent attachment of small molecules
-
Weissleder, R.; Kelly, K.; Sun, E. Y.; Shtatland, T.; Josephson, L. Cell-specific targeting of nanoparticles by multivalent attachment of small molecules. Nat. Biotechnol.2005, 23, 1418–1423.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1418-1423
-
-
Weissleder, R.1
Kelly, K.2
Sun, E.Y.3
Shtatland, T.4
Josephson, L.5
-
9
-
-
25144471199
-
Tunable inhibition and denaturation of α-chymotrypsin with amino acid-functionalized gold nanoparticles
-
You, C. C.; De, M.; Han, G.; Rotello, V. M. Tunable inhibition and denaturation of α-chymotrypsin with amino acid-functionalized gold nanoparticles. J. Am. Chem. Soc.2005, 127, 12873–12881.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 12873-12881
-
-
You, C.C.1
De, M.2
Han, G.3
Rotello, V.M.4
-
10
-
-
33847789142
-
Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles
-
Cedervall, T.; Lynch, I.; Lindman, S.; Berggard, T.; Thulin, E.; Nilsson, H.; Dawson, K. A.; Linse, S. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc. Natl. Acad. Sci. USA2007, 104, 2050–2055.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 2050-2055
-
-
Cedervall, T.1
Lynch, I.2
Lindman, S.3
Berggard, T.4
Thulin, E.5
Nilsson, H.6
Dawson, K.A.7
Linse, S.8
-
11
-
-
84864241697
-
Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells
-
Lesniak, A.; Fenaroli, F.; Monopoli, M. R.; Aberg, C.; Dawson, K. A.; Salvati, A. Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells. ACS Nano2012, 6, 5845–5857.
-
(2012)
ACS Nano
, vol.6
, pp. 5845-5857
-
-
Lesniak, A.1
Fenaroli, F.2
Monopoli, M.R.3
Aberg, C.4
Dawson, K.A.5
Salvati, A.6
-
12
-
-
55749091647
-
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
-
Lundqvist, M.; Stigler, J.; Elia, G.; Lynch, I.; Cedervall, T.; Dawson, K. A. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. Natl. Acad. Sci. USA2008, 105, 14265–14270.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14265-14270
-
-
Lundqvist, M.1
Stigler, J.2
Elia, G.3
Lynch, I.4
Cedervall, T.5
Dawson, K.A.6
-
13
-
-
84869164498
-
Modeling biological activities of nanoparticles
-
Epa, V. C.; Burden, F. R.; Tassa, C.; Weissleder, R.; Shaw, S.; Winkler, D. A. Modeling biological activities of nanoparticles. Nano Lett.2012, 12, 5808–5812.
-
(2012)
Nano Lett.
, vol.12
, pp. 5808-5812
-
-
Epa, V.C.1
Burden, F.R.2
Tassa, C.3
Weissleder, R.4
Shaw, S.5
Winkler, D.A.6
-
14
-
-
84888880735
-
Particle carriers for combating multidrug-resistant cancer
-
Yan, Y.; Bjoernmalm, M.; Caruso, F. Particle carriers for combating multidrug-resistant cancer. ACS Nano2013, 7, 9512–9517.
-
(2013)
ACS Nano
, vol.7
, pp. 9512-9517
-
-
Yan, Y.1
Bjoernmalm, M.2
Caruso, F.3
-
15
-
-
84894622648
-
60@lysozyme: Direct observation by nuclear magnetic resonance of a 1:1 fullerene protein adduct
-
60@lysozyme: Direct observation by nuclear magnetic resonance of a 1:1 fullerene protein adduct. ACS Nano2014, 8, 1871–1877.
-
(2014)
ACS Nano
, vol.8
, pp. 1871-1877
-
-
Calvaresi, M.1
Arnesano, F.2
Bonacchi, S.3
Bottoni, A.4
Calò, V.5
Conte, S.6
Falini, G.7
Fermani, S.8
Losacco, M.9
Montalti, M.10
-
16
-
-
3042673717
-
Expression and localization of acetylcholine-esterase at the neuromuscular junction
-
Rotundo, R. L. Expression and localization of acetylcholine-esterase at the neuromuscular junction. J. Neurocytol.2003, 32, 743–766.
-
(2003)
J. Neurocytol.
, vol.32
, pp. 743-766
-
-
Rotundo, R.L.1
-
17
-
-
0141818332
-
Cholinergic function and Alzheimer’s disease
-
Giacobini, E. Cholinergic function and Alzheimer’s disease. Int. J. Geriatr Psych.2003, 18, S1–S5.
-
(2003)
Int. J. Geriatr Psych.
, vol.18
, pp. 1-5
-
-
Giacobini, E.1
-
18
-
-
0018129338
-
Changes in brain cholinesterases in senile dementia of Alzheimer type
-
Perry, E. K.; Perry, R. H.; Blessed, G.; Tomlinson, B. E. Changes in brain cholinesterases in senile dementia of Alzheimer type. Neuropath. Appl. Neuro.1978, 4, 273–277.
-
(1978)
Neuropath. Appl. Neuro.
, vol.4
, pp. 273-277
-
-
Perry, E.K.1
Perry, R.H.2
Blessed, G.3
Tomlinson, B.E.4
-
19
-
-
0018078940
-
Correlation of cholinergic abnormalities with senile plaques and mental test-scores in senile dementia
-
Perry, E. K.; Tomlinson, B. E.; Blessed, G.; Bergmann, K.; Gibson, P. H.; Perry, R. H. Correlation of cholinergic abnormalities with senile plaques and mental test-scores in senile dementia. Brit. Med. J.1978, 2, 1457–1459.
-
(1978)
Brit. Med. J.
, vol.2
, pp. 1457-1459
-
-
Perry, E.K.1
Tomlinson, B.E.2
Blessed, G.3
Bergmann, K.4
Gibson, P.H.5
Perry, R.H.6
-
20
-
-
84863229484
-
Donepezil and memantine for moderate-to-severe Alzheimer’s disease
-
Howard, R.; McShane, R.; Lindesay, J.; Ritchie, C.; Baldwin, A.; Barber, R.; Burns, A.; Dening, T.; Findlay, D.; Holmes, C. et al. Donepezil and memantine for moderate-to-severe Alzheimer’s disease. New Engl. J. Med.2012, 366, 893–903.
-
(2012)
New Engl. J. Med.
, vol.366
, pp. 893-903
-
-
Howard, R.1
McShane, R.2
Lindesay, J.3
Ritchie, C.4
Baldwin, A.5
Barber, R.6
Burns, A.7
Dening, T.8
Findlay, D.9
Holmes, C.10
-
21
-
-
33745438493
-
Design and activity of cationic fullerene derivatives as inhibitors of acetylcholinesterase
-
Pastorin, G.; Marchesan, S.; Hoebeke, J.; Da Ros, T.; Ehret-Sabatier, L.; Briand, J. P.; Prato, M.; Bianco, A. Design and activity of cationic fullerene derivatives as inhibitors of acetylcholinesterase. Org. Biomol. Chem.2006, 4, 2556–2562.
-
(2006)
Org. Biomol. Chem.
, vol.4
, pp. 2556-2562
-
-
Pastorin, G.1
Marchesan, S.2
Hoebeke, J.3
Da Ros, T.4
Ehret-Sabatier, L.5
Briand, J.P.6
Prato, M.7
Bianco, A.8
-
22
-
-
65749117793
-
Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
-
Aggarwal, P.; Hall, J. B.; McLeland, C. B.; Dobrovolskaia, M. A.; McNeil, S. E. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv. Drug Deliver. Rev.2009, 61, 428–437.
-
(2009)
Adv. Drug Deliver. Rev.
, vol.61
, pp. 428-437
-
-
Aggarwal, P.1
Hall, J.B.2
McLeland, C.B.3
Dobrovolskaia, M.A.4
McNeil, S.E.5
-
23
-
-
84862737662
-
Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents
-
Adikrisna, R.; Tanaka, S.; Muramatsu, S.; Aihara, A.; Ban, D.; Ochiai, T.; Irie, T.; Kudo, A.; Nakamura, N.; Yamaoka, S. et al. Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterology.2012, 143, 234–245.
-
(2012)
Gastroenterology.
, vol.143
, pp. 234-245
-
-
Adikrisna, R.1
Tanaka, S.2
Muramatsu, S.3
Aihara, A.4
Ban, D.5
Ochiai, T.6
Irie, T.7
Kudo, A.8
Nakamura, N.9
Yamaoka, S.10
-
24
-
-
41749116115
-
Protein binding by functionalized multiwalled carbon nanotubes is governed by the surface chemistry of both parties and the nanotube diameter
-
Mu, Q. X.; Liu, W.; Xing, Y. H.; Zhou, H. Y.; Li, Z. W.; Zhang, Y.; Ji, L. H.; Wang, F.; Si, Z. K.; Zhang, B. et al. Protein binding by functionalized multiwalled carbon nanotubes is governed by the surface chemistry of both parties and the nanotube diameter. J. Phys. Chem. C2008, 112, 3300–3307.
-
(2008)
J. Phys. Chem. C
, vol.112
, pp. 3300-3307
-
-
Mu, Q.X.1
Liu, W.2
Xing, Y.H.3
Zhou, H.Y.4
Li, Z.W.5
Zhang, Y.6
Ji, L.H.7
Wang, F.8
Si, Z.K.9
Zhang, B.10
-
25
-
-
79851497437
-
Enhancing cell recognition by scrutinizing cell surfaces with a nanoparticle array
-
Zhou, H. Y.; Jiao, P. F.; Yang, L.; Li, X.; Yan, B. Enhancing cell recognition by scrutinizing cell surfaces with a nanoparticle array. J. Am. Chem. Soc.2011, 133, 680–682.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 680-682
-
-
Zhou, H.Y.1
Jiao, P.F.2
Yang, L.3
Li, X.4
Yan, B.5
-
26
-
-
77952827185
-
Structural confirmation and quantification of individual ligands from the surface of multi-functionalized gold nanoparticles
-
Zhou, H. Y.; Li, X.; Lemoff, A.; Zhang, B.; Yan, B. Structural confirmation and quantification of individual ligands from the surface of multi-functionalized gold nanoparticles. Analyst2010, 135, 1210–1213.
-
(2010)
Analyst
, vol.135
, pp. 1210-1213
-
-
Zhou, H.Y.1
Li, X.2
Lemoff, A.3
Zhang, B.4
Yan, B.5
-
27
-
-
0032516433
-
Toward understanding tryptophan fluorescence in proteins
-
Chen, Y.; Barkley, M. D. Toward understanding tryptophan fluorescence in proteins. Biochem.1998, 37, 9976–9982.
-
(1998)
Biochem.
, vol.37
, pp. 9976-9982
-
-
Chen, Y.1
Barkley, M.D.2
-
28
-
-
0039632504
-
The state of tyrosine in egg albumin and in insulin as determined by spectrophotometric titration
-
Crammer, J.; Neuberger, A. The state of tyrosine in egg albumin and in insulin as determined by spectrophotometric titration. Biochem. J.1943, 37, 302–310.
-
(1943)
Biochem. J.
, vol.37
, pp. 302-310
-
-
Crammer, J.1
Neuberger, A.2
-
29
-
-
70449159833
-
Ultraviolet fluorescence of the aromatic amino acids
-
Teale, F. W. J.; Weber, G. Ultraviolet fluorescence of the aromatic amino acids. Biochem. J.1957, 65, 476–482.
-
(1957)
Biochem. J.
, vol.65
, pp. 476-482
-
-
Teale, F.W.J.1
Weber, G.2
-
30
-
-
84870441792
-
Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces
-
Epa, V. C.; Yang, J.; Mei, Y.; Hook, A. L.; Langer, R.; Anderson, D. G.; Davies, M. C.; Alexander, M. R.; Winkler, D. A. Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces. J. Mater. Chem.2012, 22, 20902–20906.
-
(2012)
J. Mater. Chem.
, vol.22
, pp. 20902-20906
-
-
Epa, V.C.1
Yang, J.2
Mei, Y.3
Hook, A.L.4
Langer, R.5
Anderson, D.G.6
Davies, M.C.7
Alexander, M.R.8
Winkler, D.A.9
-
31
-
-
67949124727
-
Optimal sparse descriptor selection for QSAR using Bayesian methods
-
Burden, F. R.; Winkler, D. A. Optimal sparse descriptor selection for QSAR using Bayesian methods. QSAR Comb. Sci.2009, 28, 645–653.
-
(2009)
QSAR Comb. Sci.
, vol.28
, pp. 645-653
-
-
Burden, F.R.1
Winkler, D.A.2
-
32
-
-
0033549850
-
Robust QSAR models using Bayesian regularized neural networks
-
Burden, F. R.; Winkler, D. A. Robust QSAR models using Bayesian regularized neural networks. J. Med. Chem.1999, 42, 3183–3187.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 3183-3187
-
-
Burden, F.R.1
Winkler, D.A.2
-
33
-
-
76749109588
-
An optimal self-pruning neural network and nonlinear descriptor selection in QSAR
-
Burden, F. R.; Winkler, D. A. An optimal self-pruning neural network and nonlinear descriptor selection in QSAR. QSAR Comb. Sci.2009, 28, 1092–1097.
-
(2009)
QSAR Comb. Sci.
, vol.28
, pp. 1092-1097
-
-
Burden, F.R.1
Winkler, D.A.2
-
34
-
-
84879698395
-
Aqueous solubility prediction: Do crystal lattice interactions help?
-
Salahinejad, M.; Le, T. C.; Winkler, D. A. Aqueous solubility prediction: Do crystal lattice interactions help? Mol. Pharmaceut.2013, 10, 2757–2766.
-
(2013)
Mol. Pharmaceut.
, vol.10
, pp. 2757-2766
-
-
Salahinejad, M.1
Le, T.C.2
Winkler, D.A.3
-
35
-
-
84873023995
-
Capturing the crystal: Prediction of enthalpy of sublimation, crystal lattice energy, and melting points of organic compounds
-
Salahinejad, M.; Le, T. C.; Winkler, D. A. Capturing the crystal: Prediction of enthalpy of sublimation, crystal lattice energy, and melting points of organic compounds. J. Chem. Inf. Model.2013, 53, 223–229.
-
(2013)
J. Chem. Inf. Model.
, vol.53
, pp. 223-229
-
-
Salahinejad, M.1
Le, T.C.2
Winkler, D.A.3
-
36
-
-
84886785069
-
Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility
-
Cheung, J.; Gary, E. N.; Shiomi, K.; Rosenberry, T. L. Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility. ACS Med. Chem. Lett.2013, 4, 1091–1096.
-
(2013)
ACS Med. Chem. Lett.
, vol.4
, pp. 1091-1096
-
-
Cheung, J.1
Gary, E.N.2
Shiomi, K.3
Rosenberry, T.L.4
-
37
-
-
33644811612
-
A new and rapid colorimetric determination of acetylcholinesterase activity
-
Ellman, G. L.; Courtney, K. D.; Andres, V.; Featherstone, R. M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol.1961, 7, 88–95.
-
(1961)
Biochem. Pharmacol.
, vol.7
, pp. 88-95
-
-
Ellman, G.L.1
Courtney, K.D.2
Andres, V.3
Featherstone, R.M.4
-
38
-
-
0017348776
-
Hydrophobic quencher of protein fluorescence-2,2,2-trichloroethanol
-
Eftink, M. R.; Zajicek, J. L.; Ghiron, C. A. Hydrophobic quencher of protein fluorescence-2,2,2-trichloroethanol. Biochim. Biophys. Acta1977, 491, 473–481.
-
(1977)
Biochim. Biophys. Acta
, vol.491
, pp. 473-481
-
-
Eftink, M.R.1
Zajicek, J.L.2
Ghiron, C.A.3
-
39
-
-
33846390425
-
DRAGON software: An easy approach to molecular descriptor calculations
-
Mauri, A.; Consonni, V.; Pavan, M.; Todeschini, R. DRAGON software: An easy approach to molecular descriptor calculations. MATCHCommun. Math. Co.2006, 56, 237–248.
-
(2006)
MATCHCommun. Math. Co.
, vol.56
, pp. 237-248
-
-
Mauri, A.1
Consonni, V.2
Pavan, M.3
Todeschini, R.4
-
40
-
-
84861059886
-
Quantitative structure-property relationship modeling of diverse materials properties
-
Le, T.; Epa, V. C.; Burden, F. R.; Winkler, D. A. Quantitative structure-property relationship modeling of diverse materials properties. Chem. Rev.2012, 112, 2889–2919.
-
(2012)
Chem. Rev.
, vol.112
, pp. 2889-2919
-
-
Le, T.1
Epa, V.C.2
Burden, F.R.3
Winkler, D.A.4
-
41
-
-
0028543366
-
Training feed forward networks with the Marquardt algorithm
-
Hagan, M. T.; Menhaj, M. Training feed forward networks with the Marquardt algorithm. IEEE Trans. Neural Netw.1994, 5, 989–993.
-
(1994)
IEEE Trans. Neural Netw.
, vol.5
, pp. 989-993
-
-
Hagan, M.T.1
Menhaj, M.2
|