Novel in situ gel systems based on P123/TPGS mixed micelles and gellan gum for ophthalmic delivery of curcumin

Colloids and Surfaces B: Biointerfaces

Volumn 128, Issue , 2015, Pages 322-330

  Duan, Yuwei ^a   Cai, Xiaoqing ^a   Du, Hongliang ^a   Zhai, Guangxi ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Corneal penetration; Curcumin; Gellan gum; In situ gel

Indexed keywords

BIOCOMPATIBILITY; CRITICAL MICELLE CONCENTRATION; DRUG PRODUCTS;

CENTRAL COMPOSITE DESIGNS; CHARACTERIZATION TESTS; CORNEAL PENETRATION; CURCUMIN; GELLAN GUM; PHARMACOLOGICAL EFFECTS; RESPONSE SURFACE METHODOLOGY; SITU GELS;

MICELLES;

ALPHA TOCOPHEROL; ALPHA-TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; BACTERIAL POLYSACCHARIDE; CURCUMIN; DODECYL SULFATE SODIUM; DRUG CARRIER; GELLAN; IRRITANT AGENT; MACROGOL DERIVATIVE; MICELLE; NONSTEROID ANTIINFLAMMATORY AGENT; PLURONIC BLOCK COPOLYMER P123; POLOXAMER; WATER;

ANALOGS AND DERIVATIVES; ANIMAL; CHEMICAL PHENOMENA; CHEMICALLY INDUCED; CHEMISTRY; CORNEA; DRUG RELEASE; FACTORIAL ANALYSIS; INFLAMMATION; KINETICS; MALE; MICELLE; PARTICLE SIZE; PATHOLOGY; PERMEABILITY; RABBIT; SOLUBILITY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL TRANSPORT; CORNEA; CURCUMIN; DRUG CARRIERS; DRUG LIBERATION; FACTOR ANALYSIS, STATISTICAL; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFLAMMATION; IRRITANTS; KINETICS; MALE; MICELLES; PARTICLE SIZE; PERMEABILITY; POLOXALENE; POLYETHYLENE GLYCOLS; POLYSACCHARIDES, BACTERIAL; RABBITS; SODIUM DODECYL SULFATE; SOLUBILITY; VITAMIN E; WATER;

EID: 84939952207     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.02.007     Document Type: Article

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