Evaluating the genotoxicity of urban PM2.5 using PCR-based methods in human lung cells and the Salmonella TA98 reverse test

Environmental Science and Pollution Research

Volumn 22, Issue 2, 2015, Pages 1279-1289

  Traversi, Deborah ^a   Cervella, Piero ^a   Gilli, Giorgio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

AFLP; DNA damage; Gene expression; Mutagenicity; Particulate matter; Urban air pollution

Indexed keywords

AIR POLLUTANT; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA BINDING PROTEIN; MUTAGENIC AGENT; PARTICULATE MATTER; X-RAY REPAIR CROSS COMPLEMENTING PROTEIN 1;

ADVERSE EFFECTS; AIR POLLUTANT; BIOASSAY; CHEMISTRY; CYTOLOGY; DNA DAMAGE; DRUG EFFECTS; ENZYMOLOGY; EVALUATION STUDY; EXPOSURE; FIBROBLAST; GENETICS; HUMAN; LUNG; METABOLISM; MUTAGEN TESTING; PARTICLE SIZE; PARTICULATE MATTER; POLYMERASE CHAIN REACTION; PROCEDURES; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; TOXICITY;

AIR POLLUTANTS; BIOLOGICAL ASSAY; DNA DAMAGE; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; FIBROBLASTS; HUMANS; INHALATION EXPOSURE; LUNG; MUTAGENICITY TESTS; MUTAGENS; PARTICLE SIZE; PARTICULATE MATTER; POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM;

EID: 84939894339     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-014-3435-1     Document Type: Article

References (72)

1. Albinet A, Leoz-Garziandia E, Budzinski H, Villenave E, Jaffrezo JL (2008) Nitrated and oxygenated derivatives of polycyclic aromatic hydrocarbons in the ambient air of two French alpine valleys—part 1: concentrations, sources and gas/particle partitioning. Atmos Environ 42:43–54
2. Alfaro-Moreno E, Martinez L, Garcia-Cuellar C, Bonner JC, Murray JC, Rosas I, Rosales SP, Osornio-Vargas AR (2002) Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environ Health Perspect 110:715–720
3. Arase Y, Nomura J, Sugaya S, Sugita K, Kita K, Suzuki N (2002) Effects of 3-D clino-rotation on gene expression in human fibroblast cells. Cell Biol Int 26:225–233
4. ARPA Piemonte PdT (2008) Uno sguardo all’aria 2008. Provincia di Torino, Torino
5. ARPA Piemonte SP, CSI Piemonte (2014) ARIAWEB–Sistema Regionale di Rilevamento della Qualità dell’Aria della Regione Piemonte
6. Asharani P, Sethu S, Lim HK, Balaji G, Valiyaveettil S, Hande MP (2012) Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr 3:2
7. Atienzar FA, Jha AN (2006) The random amplified polymorphic DNA (RAPD) assay and related techniques applied to genotoxicity and carcinogenesis studies: a critical review. Mutat Res 613:76–102
8. Bagley MJ, Anderson SL, May B (2001) Choice of methodology for assessing genetic impacts of environmental stressors: polymorphism and reproducibility of RAPD and AFLP fingerprints. Ecotoxicology 10:239–244
9. Bassam BJ, Gresshoff PM (2007) Silver staining DNA in polyacrylamide gels. Nat Protoc 2:2649–2654
10. Bastonini E, Verdone L, Morrone S, Santoni A, Settimo G, Marsili G, La Fortezza M, Di Mauro E, Caserta M (2011) Transcriptional modulation of a human monocytic cell line exposed to PM(10) from an urban area. Environ Res 111:765–774
11. Baurand PE, de Vaufleury A, Scheifler R, Capelli N (2013) Coupling of random amplified polymorphic DNA profiles analysis and high resolution capillary electrophoresis system for the assessment of chemical genotoxicity. Environ Sci Technol 47:9505–9513
12. Beelen R, Hoek G, van den Brandt PA, Goldbohm RA, Fischer P, Schouten LJ, Armstrong B, Brunekreef B (2008) Long-term exposure to traffic-related air pollution and lung cancer risk. Epidemiology 19:702–710
13. Belpomme D, Irigaray P, Hardell L, Clapp R, Montagnier L, Epstein S, Sasco AJ (2007) The multitude and diversity of environmental carcinogens. Environ Res 105:414–429
14. Ben Salem Z, Capelli N, Grisey E, Baurand PE, Ayadi H, Aleya L (2014) First evidence of fish genotoxicity induced by heavy metals from landfill leachates: the advantage of using the RAPD-PCR technique. Ecotoxicol Environ Saf 101:90–96
15. Breznan D, Goegan P, Chauhan V, Karthikeyan S, Kumarathasan P, Cakmak S, Nadeau D, Brook JR, Vincent R (2013) Respiratory burst in alveolar macrophages exposed to urban particles is not a predictor of cytotoxicity. Toxicol in Vitro 27:1287–1297
16. Brunekreef B, Beelen R, Hoek G, Schouten L, Bausch-Goldbohm S, Fischer P, Armstrong B, Hughes E, Jerrett M, van den Brandt P (2009) Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in the Netherlands: the NLCS-AIR study. Res Rep Health Eff Inst 5–71; discussion 73–89
17. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:611–622
18. Bylund L, Kytola S, Lui WO, Larsson C, Weber G (2004) Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches. Cytogenet Genome Res 106:28–32
19. Cassoni F, Bocchi C, Martino A, Pinto G, Fontana F, Buschini A (2004) The Salmonella mutagenicity of urban airborne particulate matter (PM2.5) from eight sites of the Emilia-Romagna regional monitoring network (Italy). Sci Total Environ 324:79–90
20. CEN (1998) Air quality—determination of the PM10 fraction of suspended particulate matter—reference method and field test procedure to demonstrate reference equivalence of measurement methods. In: Standardization ECf (Hrsg.), European Standard EN 12341 Bruxelles
21. Chang LC, Sheu HM, Huang YS, Tsai TR, Kuo KW (1999) A novel function of emodin—enhancement of the nucleotide excision repair of UV- and cisplatin-induced DNA damage in human cells. Biochem Pharmacol 58:49–57
22. Claxton LD, Woodall GM Jr (2007) A review of the mutagenicity and rodent carcinogenicity of ambient air. Mutat Res 636:36–94
23. Claxton LD, Matthews PP, Warren SH (2004) The genotoxicity of ambient outdoor air, a review: Salmonella mutagenicity. Mutat Res 567:347–399
24. de Kok TM, Hogervorst JG, Briede JJ, van Herwijnen MH, Maas LM, Moonen EJ, Driece HA, Kleinjans JC (2005) Genotoxicity and physicochemical characteristics of traffic-related ambient particulate matter. Environ Mol Mutagen 46:71–80
25. Eastmond DA, Hartwig A, Anderson D, Anwar WA, Cimino MC, Dobrev I, Douglas GR, Nohmi T, Phillips DH, Vickers C (2009) Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme. Mutagenesis 24:341–349
26. EEA (2012) European Environmental Agency—air quality in Europe—2012 report Office for Official Publications of the European Union, Copenhagen
27. Eftim SE, Samet JM, Janes H, McDermott A, Dominici F (2008) Fine particulate matter and mortality: a comparison of the six cities and American Cancer Society cohorts with a medicare cohort. Epidemiology 19:209–216
28. Gallus S, Negri E, Boffetta P, McLaughlin JK, Bosetti C, La Vecchia C (2008) European studies on long-term exposure to ambient particulate matter and lung cancer. Eur J Cancer Prev 17:191–194
29. Gilli G, Pignata C, Schiliro T, Bono R, La Rosa A, Traversi D (2007) The mutagenic hazards of environmental PM2.5 in Turin. Environ Res 103:168–175
30. Grant WB (2009) Air pollution in relation to U.S. cancer mortality rates: an ecological study; likely role of carbonaceous aerosols and polycyclic aromatic hydrocarbons. Anticancer Res 29:3537–3545
31. Happo MS, Salonen RO, Halinen AI, Jalava PI, Pennanen AS, Dormans JAMA, Gerlofs-Nijland ME, Cassee FR, Kosma VM, Sillanpaa M, Hillamo R, Hirvonen MR (2010) Inflammation and tissue damage in mouse lung by single and repeated dosing of urban air coarse and fine particles collected from six European cities. Inhal Toxicol 22:402–416
32. Jain S, Khare M (2008) Urban air quality in mega cities: a case study of Delhi City using vulnerability analysis. Environ Monit Assess 136:257–265
33. Ji H, Hershey GKK (2012) Genetic and epigenetic influence on the response to environmental particulate matter. J Allergy Clin Immunol 129:33–41
34. Kam W, Delfino RJ, Schauer JJ, Sioutas C (2013) A comparative assessment of PM2.5 exposures in light-rail, subway, freeway, and surface street environments in Los Angeles and estimated lung cancer risk. Environ Sci Process Impacts 15:234–243
35. Kappos AD, Bruckmann P, Eikmann T, Englert N, Heinrich U, Hoppe P, Koch E, Krause GH, Kreyling WG, Rauchfuss K, Rombout P, Schulz-Klemp V, Thiel WR, Wichmann HE (2004) Health effects of particles in ambient air. Int J Hyg Environ Health 207:399–407
36. Krewski D, Burnett R, Jerrett M, Pope CA, Rainham D, Calle E, Thurston G, Thun M (2005) Mortality and long-term exposure to ambient air pollution: ongoing analyses based on the American Cancer Society cohort. J Toxicol Environ Health A 68:1093–1109
37. Krzyzanowski M (2008) WHO air quality guidelines for Europe. J Toxicol Environ Health A 71:47–50
38. Libalova H, Uhlirova K, Klema J, Machala M, Sram RJ, Ciganek M, Topinka J (2012) Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles. Part Fibre Toxicol 9
39. Lindgren A, Stroh E, Montnemery P, Nihlen U, Jakobsson K, Axmon A (2009) Traffic-related air pollution associated with prevalence of asthma and COPD/chronic bronchitis. A cross-sectional study in Southern Sweden. Int J Health Geogr 8:2
40. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 25:402–408
41. Loomis D, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Baan R, Mattock H, Straif K, IARC (2013) The carcinogenicity of outdoor air pollution. Lancet Oncol 14:1262–1263
42. Maruyama W, Hirano S, Kobayashi T, Aoki Y (2006) Quantitative risk analysis of particulate matter in the air: interspecies extrapolation with bioassay and mathematical models. Inhal Toxicol 18:1013–1023
43. Mehta M, Chen LC, Gordon T, Rom W, Tang MS (2008) Particulate matter inhibits DNA repair and enhances mutagenesis. Mutat Res 657:116–121
44. Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, Sandstrom T, Blomberg A, Newby DE (2009) Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med 6:36–44
45. Moller P, Folkmann JK, Forchhammer L, Brauner EV, Danielsen PH, Risom L, Loft S (2008) Air pollution, oxidative damage to DNA, and carcinogenesis. Cancer Lett 266:84–97
46. Mukherjee B, Dutta A, Roychoudhury S, Ray MR (2013) Chronic inhalation of biomass smoke is associated with DNA damage in airway cells: involvement of particulate pollutants and benzene. J Appl Toxicol 33:281–289
47. Nagdeve D (2006) Urban air pollution and its influence on human health in mega cities of India. Epidemiology 17:S261–S262
48. Nemery B, Hoet PH, Nemmar A (2001) The Meuse Valley fog of 1930: an air pollution disaster. Lancet 357:704–708
49. Nogueira JB (2009) Air pollution and cardiovascular disease. Rev Port Cardiol 28:715–733
50. Pfuhler S, Elespuru R, Aardema MJ, Doak SH, Donner EM, Honma M, Kirsch-Volders M, Landsiedel R, Manjanatha M, Singer T, Kim JH (2013) Genotoxicity of nanomaterials: refining strategies and tests for hazard identification. Environ Mol Mutagen 54:229–239
51. Pope CA 3rd (1996) Particulate pollution and health: a review of the Utah valley experience. J Expo Anal Environ Epidemiol 6:23–34
52. Pope CA 3rd (2000) Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who’s at risk? Environ Health Perspect 108(Suppl 4):713–723
53. Silva JP, Gomes AC, Coutinho OP (2008) Oxidative DNA damage protection and repair by polyphenolic compounds in PC12 cells. Eur J Pharmacol 601:50–60
54. Sorensen M, Autrup H, Hertel O, Wallin H, Knudsen LE, Loft S (2003a) Personal exposure to PM2.5 and biomarkers of DNA damage. Cancer Epidemiol Biomarkers Prev 12:191–196
55. Sorensen M, Autrup H, Moller P, Hertel O, Jensen SS, Vinzents P, Knudsen LE, Loft S (2003b) Linking exposure to environmental pollutants with biological effects. Mutat Res 544:255–271
56. Srut M, Stambuk A, Klobucar GI (2013) What is comet assay not telling us: AFLP reveals wider aspects of genotoxicity. Toxicol in Vitro 27:1226–1232
57. Ta W, Wang T, Xiao H, Zhu X, Xiao Z (2004) Gaseous and particulate air pollution in the Lanzhou Valley, China. Sci Total Environ 320:163–176
58. Traversi D, Schiliro T, Degan R, Pignata C, Alessandria L, Gilli G (2011) Involvement of nitro-compounds in the mutagenicity of urban Pm2.5 and Pm10 in Turin. Mutat Res Genet Toxicol Environ Mutagen 726:54–59
59. Valavanidis A, Fiotakis K, Vlachogianni T (2008) Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 26:339–362
60. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3
61. Vardar C, Basaran E, Cansaran-Duman D, Aras S (2014) Air-quality biomonitoring: assessment of genotoxicity of air pollution in the Province of Kayseri (Central Anatolia) by use of the lichen Pseudevernia furfuracea (L.) Zopf and amplified fragment-length polymorphism markers. Mutat Res Genet Toxicol Environ Mutagen 759:43–50
62. Viera L, Chen K, Nel A, Lloret MG (2009) The impact of air pollutants as an adjuvant for allergic sensitization and asthma. Curr Allergy Asthma Rep 9:327–333
63. Vineis P et al (2007) Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study. Environ Health 6:7
64. Vinikoor-Imler LC, Davis JA, Luben TJ (2011) An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality. Int J Environ Res Public Health 8:1865–1871
65. Voigt T, Bailey M, Abramson M (1998) Air pollution in the Latrobe Valley and its impact upon respiratory morbidity. Aust N Z J Public Health 22:556–561
66. Vos P, Hogers R, Bleeker M, Reijans M, van de Lee T, Hornes M, Frijters A, Pot J, Peleman J, Kuiper M et al (1995) AFLP: a new technique for DNA fingerprinting. Nucleic Acids Res 23:4407–4414
67. WHO (2005) Air quality guidelines—global update 2005
68. WHO-Europe (2013) Review of evidence on health aspects of air pollution—Technical Report—REVIHAAP Project
69. Wood RD, Mitchell M, Lindahl T (2005) Human DNA repair genes, 2005. Mutat Res Fundam Mol Mech Mutagen 577:275–283
70. Yang J, Wang Z, Chen W, Yin J (2013) Role of ubiquitin protein ligase Ring2 in DNA damage of human bronchial epithelial cells exposed to benzo[a]pyrene. J Biochem Mol Toxicol 27:357–363
71. Zhang M, Song Y, Cai X, Zhou J (2008) Economic assessment of the health effects related to particulate matter pollution in 111 Chinese cities by using economic burden of disease analysis. J Environ Manag 88:947–954
72. Zhang JJ, McCreanor JE, Cullinan P, Chung KF, Ohman-Strickland P, Han IK, Jarup L, Nieuwenhuijsen MJ (2009) Health effects of real-world exposure to diesel exhaust in persons with asthma. Res Rep Health Eff Inst 5–109; discussion 111–23