Endothelin receptor inhibition with bosentan delays onset of liver injury in streptozotocin-induced diabetic condition

Drug Research

Volumn 65, Issue 5, 2015, Pages 272-280

  Demirci, E ^a   Ferah, I ^b   Gundogdu, C ^a,b   Ozkanlar, S ^b   Baygutalp, N K ^b   Bayir, Y ^b   Calik, M ^a   Ayaz, G ^a  

^a ATATURK UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

Author keywords

cytokines; diabetes; endothelin; liver; oxidative stress; rat

Indexed keywords

BOSENTAN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; GLUTATHIONE; MALONALDEHYDE; STREPTOZOCIN; SULFONAMIDE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; LIVER; MALE; METABOLISM; PATHOLOGY; RAT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DRUG-INDUCED LIVER INJURY; ENDOTHELIN RECEPTOR ANTAGONISTS; ENDOTHELIN-1; GENE EXPRESSION REGULATION; GLUTATHIONE; LIVER; MALE; MALONDIALDEHYDE; RATS; STREPTOZOCIN; SULFONAMIDES; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84939885254     PISSN: 21949379     EISSN: 21949387     Source Type: Journal    
DOI: 10.1055/s-0034-1377024     Document Type: Article

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