메뉴 건너뛰기




Volumn 15, Issue 12, 2015, Pages 1002-1010

The medical Use of wheatgrass: Review of the gap between basic and clinical applications

Author keywords

Apoptosis; Cancer; Hematological diseases; Immunology; Oxidative stress; Triticum aestivum; Wheatgrass

Indexed keywords

ALPHA TOCOPHEROL; ANASTROZOLE; ASCORBIC ACID; BENZOQUINONE; CHLOROPHYLL; CISPLATIN; CYCLOOXYGENASE 2; DACARBAZINE; DEXAMETHASONE; EXEMESTANE; FERMENTED WHEAT GERM EXTRACT; FLAVONOID; FLUOROURACIL; INDOMETACIN; IRINOTECAN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXALIPLATIN; PLANT EXTRACT; TAMOXIFEN; TRITICUM AESTIVUM EXTRACT; UNCLASSIFIED DRUG; WHEATGRASS JUICE EXTRACT;

EID: 84939832440     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955751512150731112836     Document Type: Article
Times cited : (40)

References (78)
  • 1
    • 84907506431 scopus 로고    scopus 로고
    • Wound healing potential of young leaves of Triticum Aestivum on alloxan induced diabetic rats
    • [1] Jain, G.; Jain, N.; Argal, A. Wound healing potential of young leaves of Triticum Aestivum on alloxan induced diabetic rats. Int. J. Pharm. Pharm. Sci., 2014, 6, 508-513.
    • (2014) Int. J. Pharm. Pharm. Sci , vol.6 , pp. 508-513
    • Jain, G.1    Jain, N.2    Argal, A.3
  • 2
    • 0002373884 scopus 로고
    • Chlorophyll: The active factor in wheat sprout extracts inhibiting the metabolic activation of carcinogens in vitro
    • [2] Lai, C.N. Chlorophyll: the active factor in wheat sprout extracts inhibiting the metabolic activation of carcinogens in vitro. Nutr Cancer, 1979, 1, 19-21.
    • (1979) Nutr Cancer , vol.1 , pp. 19-21
    • Lai, C.N.1
  • 3
    • 0034721581 scopus 로고    scopus 로고
    • Chlorophyllin as an effective antioxidant against membrane damage in vitro and ex vivo
    • [3] Kamat, J.P.; Boloor, K.K.; Devasagayam, T.P. Chlorophyllin as an effective antioxidant against membrane damage in vitro and ex vivo. Biochim Biophys Acta., 2000, 1487, 113-127.
    • (2000) Biochim Biophys Acta , vol.1487 , pp. 113-127
    • Kamat, J.P.1    Boloor, K.K.2    Devasagayam, T.P.3
  • 4
    • 22844437903 scopus 로고    scopus 로고
    • Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes
    • [4] Fahey, J.W.; Stephenson, K.K.; Dinkova-Kostova, A.T.; Egner, P.A.; Kensler, T.W.; Talalay, P. Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes. Carcinogenesis, 2005, 26, 1247-1255.
    • (2005) Carcinogenesis , vol.26 , pp. 1247-1255
    • Fahey, J.W.1    Stephenson, K.K.2    Dinkova-Kostova, A.T.3    Egner, P.A.4    Kensler, T.W.5    Talalay, P.6
  • 5
    • 0038378322 scopus 로고    scopus 로고
    • Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis
    • [5] Talalay, P.; Dinkova-Kostova, A.T.; Holtzclaw, W.D. Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis. Adv. Enzyme Regul., 2003, 43, 121-134.
    • (2003) Adv. Enzyme Regul , vol.43 , pp. 121-134
    • Talalay, P.1    Dinkova-Kostova, A.T.2    Holtzclaw, W.D.3
  • 6
    • 0034735891 scopus 로고    scopus 로고
    • Chlorophyllin as a protector of mitochondrial membranes against gamma-radiation and photosensitization
    • [6] Boloor, K.K.; Kamat, J.P.; Devasagayam, T.P. Chlorophyllin as a protector of mitochondrial membranes against gamma-radiation and photosensitization. Toxicology, 2000, 155, 63–71.
    • (2000) Toxicology , vol.155 , pp. 63-71
    • Boloor, K.K.1    Kamat, J.P.2    Devasagayam, T.P.3
  • 7
    • 0029083486 scopus 로고
    • Flavonoids as antioxidant agents: Importance of their interaction with biomembranes
    • [7] Saija, A.; Scalese, M.; Lanza, M.; Marzullo, D.; Bonina, F.; Castelli F. Flavonoids as antioxidant agents: importance of their interaction with biomembranes. Free Rad. Biol. Med., 1995, 19, 481-486.
    • (1995) Free Rad. Biol. Med , vol.19 , pp. 481-486
    • Saija, A.1    Scalese, M.2    Lanza, M.3    Marzullo, D.4    Bonina, F.5    Castelli, F.6
  • 8
    • 80051896049 scopus 로고    scopus 로고
    • Kasahara, T. Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
    • [8] Funakoshi-Tago, M.; Nakamura, K.; Tago, K.; Mashino, T.; Kasahara, T. Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin. Int. Immunopharmacol., 2011, 11, 1150-1159.
    • (2011) Int. Immunopharmacol , vol.11 , pp. 1150-1159
    • Funakoshi-Tago, M.1    Nakamura, K.2    Tago, K.3    Mashino, T.4
  • 9
    • 0029080130 scopus 로고
    • Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression
    • [9] Gerritsen, M.E.; Carley, W.W.; Ranges, G.E. Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. Am. J. Pathol., 1995, 147, 278-292.
    • (1995) Am. J. Pathol , vol.147 , pp. 278-292
    • Gerritsen, M.E.1    Carley, W.W.2    Ranges, G.E.3
  • 10
    • 34248226610 scopus 로고    scopus 로고
    • Apigenin and cancer chemoprevention: Progress, potential and promise (review)
    • [10] Patel, D.; Shukla, S.; Gupta, S. Apigenin and cancer chemoprevention: progress, potential and promise (review). Int. J. Oncol., 2007, 30, 233-245.
    • (2007) Int. J. Oncol , vol.30 , pp. 233-245
    • Patel, D.1    Shukla, S.2    Gupta, S.3
  • 11
    • 33750720916 scopus 로고    scopus 로고
    • Apigenin suppresses cancer cell growth through ERbeta
    • [11] Mak, P.; Leung, Y.K.; Tang, W.Y.; Harwood, C.; Ho, S.M. Apigenin suppresses cancer cell growth through ERbeta. Neoplasia, 2006, 8, 896-904.
    • (2006) Neoplasia , vol.8 , pp. 896-904
    • Mak, P.1    Leung, Y.K.2    Tang, W.Y.3    Harwood, C.4    Ho, S.M.5
  • 12
    • 84882791459 scopus 로고    scopus 로고
    • Targeting the PI3K/Akt/mTOR axis by apigenin for cancer prevention
    • [12] Tong, X.; Pelling, J.C. Targeting the PI3K/Akt/mTOR axis by apigenin for cancer prevention. Anticancer Agents Med. Chem., 2013, 13, 971-978.
    • (2013) Anticancer Agents Med. Chem , vol.13 , pp. 971-978
    • Tong, X.1    Pelling, J.C.2
  • 13
    • 84898655744 scopus 로고    scopus 로고
    • Apigenin induces the apoptosis and regulates MAPK signaling pathways in mouse macrophage ANA-1 cells
    • [13] Liao, Y.; Shen, W.; Kong, G.; Lv, H.; Tao, W.; Bo, P. Apigenin induces the apoptosis and regulates MAPK signaling pathways in mouse macrophage ANA-1 cells. PLoS One, 2014, 9, e92007.
    • (2014) Plos One , vol.92007 , pp. 9
    • Liao, Y.1    Shen, W.2    Kong, G.3    Lv, H.4    Tao, W.5    Bo, P.6
  • 14
    • 84859701223 scopus 로고    scopus 로고
    • Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel
    • [14] Ma, X.; He, D.; Ru, X.; Chen, Y.; Cai, Y.; Bruce, I.C.; Xia, Q.; Yao, X.; Jin, J. Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel. Br. J. Pharmacol., 2012, 166, 349-358.
    • (2012) Br. J. Pharmacol , vol.166 , pp. 349-358
    • Ma, X.1    He, D.2    Ru, X.3    Chen, Y.4    Cai, Y.5    Bruce, I.C.6    Xia, Q.7    Yao, X.8    Jin, J.9
  • 15
    • 84879307951 scopus 로고    scopus 로고
    • Ascorbic acid in cancer chemoprevention: Translational perspectives and efficacy
    • [15] Ullah, M.F.; Bhat, S.H.; Hussain, E.; Abu-Duhier, F.; Ahmad, A.; Hadi, S.M. Ascorbic acid in cancer chemoprevention: translational perspectives and efficacy. Curr Drug Targets, 2012, 13, 1757-1771.
    • (2012) Curr Drug Targets , vol.13 , pp. 1757-1771
    • Ullah, M.F.1    Bhat, S.H.2    Hussain, E.3    Abu-Duhier, F.4    Ahmad, A.5    Hadi, S.M.6
  • 16
  • 17
    • 34547450536 scopus 로고    scopus 로고
    • Head and neck cancer: A case for inhibition by isothiocyanates and indoles from cruciferous vegetables
    • [17] Fowke, J.H. Head and neck cancer: a case for inhibition by isothiocyanates and indoles from cruciferous vegetables. Eur. J. Cancer Prev., 2007, 16, 348-356.
    • (2007) Eur. J. Cancer Prev , vol.16 , pp. 348-356
    • Fowke, J.H.1
  • 18
    • 84870656636 scopus 로고    scopus 로고
    • The role of choline in prostate cancer
    • [18] Awwad, H.M.; Geisel, J.; Obeid, R. The role of choline in prostate cancer. Clin. Biochem., 2012, 45, 1548-1553.
    • (2012) Clin. Biochem , vol.45 , pp. 1548-1553
    • Awwad, H.M.1    Geisel, J.2    Obeid, R.3
  • 19
    • 79953245461 scopus 로고    scopus 로고
    • Hypolipidemic effect of fresh Triticum aestivum (Wheat) grass juice in hypercholesterolemic rats
    • [19] Kothari, S.; Jain, A.K.;, Mehta, S.C.; Tonpay, S.D. Hypolipidemic effect of fresh Triticum aestivum (wheat) grass juice in hypercholesterolemic rats. Acta Pol. Pharm., 2011, 68, 291-294.
    • (2011) Acta Pol. Pharm , vol.68 , pp. 291-294
    • Kothari, S.1    Jain, A.K.2    Mehta, S.C.3    Tonpay, S.D.4
  • 20
    • 84908150799 scopus 로고    scopus 로고
    • Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass
    • [20] Durairaj, V.; Hoda, M.; Shakya, G.; Babu, S.P.; Rajagopalan, R. Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass. Asian Pac. J. Trop. Med., 2014, 7S1, S398-S404.
    • (2014) Asian Pac. J. Trop. Med , vol.7S1
    • Durairaj, V.1    Hoda, M.2    Shakya, G.3    Babu, S.P.4    Rajagopalan, R.5
  • 22
    • 84930661647 scopus 로고    scopus 로고
    • P compounds in grains, sprouts and wheatgrass of hulled and non-hulled wheat species
    • [Epub ahead of print]
    • [22] Benincasa, P.; Galieni, A.; Manetta, A.C.; Pace, R.; Guiducci, M.; Pisante, M.; Stagnari, F. Phenolic compounds in grains, sprouts and wheatgrass of hulled and non-hulled wheat species. J. Sci. Food Agric., 2014. doi: 10.1002/jsfa.6877. [Epub ahead of print].
    • (2014) J. Sci. Food Agric
    • Benincasa, P.1    Galieni, A.2    Manetta, A.C.3    Pace, R.4    Guiducci, M.5    Pisante, M.6    Stagnari, F.7
  • 24
    • 33645464260 scopus 로고    scopus 로고
    • Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions
    • [24] Kulkarni, S.D.; Tilak, J.C.; Acharya, R.; Rajurkar, N.S.; Devasagayam, T.P.; Reddy, A.V. Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions. Phytother. Res., 2006, 20, 218-227.
    • (2006) Phytother. Res , vol.20 , pp. 218-227
    • Kulkarni, S.D.1    Tilak, J.C.2    Acharya, R.3    Rajurkar, N.S.4    Devasagayam, T.P.5    Reddy, A.V.6
  • 25
    • 34447540131 scopus 로고    scopus 로고
    • Wheat grass juice may improve hematological toxicity related to chemotherapy in breast cancer patients: A pilot study
    • [25] Bar-Sela, G.; Tsalic, M.; Fried, G.; Goldberg, H. Wheat grass juice may improve hematological toxicity related to chemotherapy in breast cancer patients: a pilot study, Nutr. Cancer, 2007, 58, 43-48.
    • (2007) Nutr. Cancer , vol.58 , pp. 43-48
    • Bar-Sela, G.1    Tsalic, M.2    Fried, G.3    Goldberg, H.4
  • 26
    • 84865318459 scopus 로고    scopus 로고
    • Effect of freeze drying and oven drying on antioxidant properties of fresh wheatgrass
    • [26] Das, A.; Raychaudhuri, U.; Chakraborty, R. Effect of freeze drying and oven drying on antioxidant properties of fresh wheatgrass. Int. J. Food Sci. Nutr., 2012, 63, 718-721.
    • (2012) Int. J. Food Sci. Nutr , vol.63 , pp. 718-721
    • Das, A.1    Raychaudhuri, U.2    Chakraborty, R.3
  • 27
    • 34250309936 scopus 로고    scopus 로고
    • Safety studies regarding a standardized extract of fermented wheat germ
    • [27] Heimbach, J.T.; Sebestyen, G.; Semjen, G.; Kennepohl, E. Safety studies regarding a standardized extract of fermented wheat germ. Int. J. Toxicol., 2007, 26, 253-259.
    • (2007) Int. J. Toxicol , vol.26 , pp. 253-259
    • Heimbach, J.T.1    Sebestyen, G.2    Semjen, G.3    Kennepohl, E.4
  • 30
    • 84890562828 scopus 로고    scopus 로고
    • Antioxidant profiling of Triticum aestivum (Wheatgrass) and its antiproliferative activity in MCF-7 breast cancer cell line
    • [30] Tandon, S.; Arora, A.; Singh, S.; Monga, J.; Arora, S. Antioxidant profiling of Triticum aestivum (wheatgrass) and its antiproliferative activity in MCF-7 breast cancer cell line. J. Pharm. Res., 2011, 4, 4601-4604.
    • (2011) J. Pharm. Res , vol.4 , pp. 4601-4604
    • Tandon, S.1    Arora, A.2    Singh, S.3    Monga, J.4    Arora, S.5
  • 31
    • 84901245228 scopus 로고    scopus 로고
    • Growth inhibitory and adjuvant therapeutic potential of aqueous extract of Triticum aestivum on MCF-7 and HeLa cells
    • [31] Hussain, A.; Gheewala, T.M.; Vas, A.J.; Shah, K.; Goala, P.; Khan, S.; Hinduja, S.; Sharma, C. Growth inhibitory and adjuvant therapeutic potential of aqueous extract of Triticum aestivum on MCF-7 and HeLa cells. Exp. Oncol., 2014, 36, 9-16.
    • (2014) Exp. Oncol , vol.36 , pp. 9-16
    • Hussain, A.1    Gheewala, T.M.2    Vas, A.J.3    Shah, K.4    Goala, P.5    Khan, S.6    Hinduja, S.7    Sharma, C.8
  • 32
    • 79960019388 scopus 로고    scopus 로고
    • Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60)
    • [32] Alitheen, N.B.; Oon, C.L.; Keong, Y.S.; Chuan, T.K.; Li, H.K.; Yong, H.W. Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60). Pak. J. Pharm. Sci., 2011, 24, 243-250.
    • (2011) Pak. J. Pharm. Sci , vol.24 , pp. 243-250
    • Alitheen, N.B.1    Oon, C.L.2    Keong, Y.S.3    Chuan, T.K.4    Li, H.K.5    Yong, H.W.6
  • 33
    • 33746646909 scopus 로고    scopus 로고
    • Cytotoxic activities of fermented wheat germ extract on human gastric carcinoma cells by induction of apoptosis
    • [Abstract 4254, 2005 ASCO Annual Meeting]
    • [33] Lee, S.N.; Park, H.; Lee, K.E. Cytotoxic activities of fermented wheat germ extract on human gastric carcinoma cells by induction of apoptosis. J. Clin. Oncol., 2005, 23, 16S. [Abstract 4254, 2005 ASCO Annual Meeting].
    • (2005) J. Clin. Oncol , vol.23
    • Lee, S.N.1    Park, H.2    Lee, K.E.3
  • 37
    • 79955116967 scopus 로고    scopus 로고
    • Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines
    • [37] Mueller, T.; Jordan, K.; Voigt, W. Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines. J. Exp. Clin. Cancer Res., 2011, 30, 42.
    • (2011) J. Exp. Clin. Cancer Res , vol.30 , pp. 42
    • Mueller, T.1    Jordan, K.2    Voigt, W.3
  • 38
    • 2242485601 scopus 로고    scopus 로고
    • Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells
    • [38] Comin-Anduix, B.; Boros, L.G.; Marin, S.; Boren, J.; Callol- Massot, C.; Centelles, J.J.; Torres, J.L.; Agell, N.; Bassilian, S.; Cascante, M. Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. J. Biol. Chem., 2002, 277, 46408-46414.
    • (2002) J. Biol. Chem , vol.277 , pp. 46408-46414
    • Comin-Anduix, B.1    Boros, L.G.2    Marin, S.3    Boren, J.4    Callol- Massot, C.5    Centelles, J.J.6    Torres, J.L.7    Agell, N.8    Bassilian, S.9    Cascante, M.10
  • 39
    • 84896741363 scopus 로고    scopus 로고
    • Fermented wheat germ extract induced cell death and enhanced cytotoxicity of Cisplatin and 5- Fluorouracil on human hepatocellular carcinoma cells
    • [39] Tai, C.J.; Wang, W.C.; Wang, C.K.; Wu, C.H.; Yang, M.D.; Chang, Y.J.; Jian, J.Y.; Tai, C.J. Fermented wheat germ extract induced cell death and enhanced cytotoxicity of Cisplatin and 5- Fluorouracil on human hepatocellular carcinoma cells. Evid. Based Complement. Alternat. Med., 2013, 121725.
    • (2013) Evid. Based Complement. Alternat. Med , pp. 121725
    • Tai, C.J.1    Wang, W.C.2    Wang, C.K.3    Wu, C.H.4    Yang, M.D.5    Chang, Y.J.6    Jian, J.Y.7    Tai, C.J.8
  • 40
    • 0034915207 scopus 로고    scopus 로고
    • Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells
    • [40] Boros, L.G.; Lapis, K.; Szende, B.; Tömösközi-Farkas, R.; Balogh, Á.; Boren, J.; Marin, S.; Cascante, M.; Hidvégi, M. Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Pancreas, 2001, 23, 141–147.
    • (2001) Pancreas , vol.23 , pp. 141-147
    • Boros, L.G.1    Lapis, K.2    Szende, B.3    Tömösközi-Farkas, R.4    Balogh, B.5    Boren, J.6    Marin, S.7    Cascante, M.8    Hidvégi, M.9
  • 41
    • 14044265107 scopus 로고    scopus 로고
    • The  efficacy of tamoxifen in estrogen receptor-positive breast cancer cells is enhanced by a medical nutriment. Cancer Biother
    • [41] Marcsek, Z.; Kocsis, Z.; Jakab, M.; Szende, B.; Tompa, A. The  efficacy of tamoxifen in estrogen receptor-positive breast cancer cells is enhanced by a medical nutriment. Cancer Biother. Radiopharm., 2004, 19, 746-753.
    • (2004) Radiopharm , vol.19 , pp. 746-753
    • Marcsek, Z.1    Kocsis, Z.2    Jakab, M.3    Szende, B.4    Tompa, A.5
  • 42
    • 0033590207 scopus 로고    scopus 로고
    • The role of cyclooxygenases in inflammation, cancer, and development
    • [42] Williams, C.S.; Mann, M.; DuBois, R.N. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene, 1999, 18, 7908-7916.
    • (1999) Oncogene , vol.18 , pp. 7908-7916
    • Williams, C.S.1    Mann, M.2    Dubois, R.N.3
  • 44
    • 84896871789 scopus 로고    scopus 로고
    • Evaluation of the cytotoxic effects of CAM therapies: An in vitro study in normal kidney cell lines
    • [44] Arora, S.; Tandon, C.; Tandon, S. Evaluation of the cytotoxic effects of CAM therapies: an in vitro study in normal kidney cell lines. Scientific World Journal, 2014, 452892.
    • (2014) Scientific World Journal , pp. 452892
    • Arora, S.1    Tandon, C.2    Tandon, S.3
  • 46
    • 79958747121 scopus 로고    scopus 로고
    • Chemoprevention by Triticum Aestivum of mouse skin carcinogenesis induced by DMBA and croton oil - association with oxidative status
    • [46] Arya, P.; Kumar, M. Chemoprevention by Triticum Aestivum of mouse skin carcinogenesis induced by DMBA and croton oil - association with oxidative status. Asian Pac. J. Cancer Prev., 2011, 12, 143-148.
    • (2011) Asian Pac. J. Cancer Prev , vol.12 , pp. 143-148
    • Arya, P.1    Kumar, M.2
  • 47
    • 51349168942 scopus 로고    scopus 로고
    • Avemar inhibits the growth of mouse and human xenograft mammary carcinomas comparable to endocrine treatments
    • [47] Tejeda, M.; Gaál, D.; Szűcs, I.; Telekes, A. Avemar inhibits the growth of mouse and human xenograft mammary carcinomas comparable to endocrine treatments. J. Clin. Oncol., 2007, 25, 21132.
    • (2007) J. Clin. Oncol , vol.25 , pp. 21132
    • Tejeda, M.1    Gaál, D.2    Szűcs, I.3    Telekes, A.4
  • 48
    • 3142689713 scopus 로고    scopus 로고
    • Effect of simultaneous administration of Avemar and cytostatic drugs on viability of cell cultures, growth of experimental tumors, and survival tumor-bearing mice
    • [48] Szende, B.; Marcsek, Z.; Kocsis, Z.; Tompa, A. Effect of simultaneous administration of Avemar and cytostatic drugs on viability of cell cultures, growth of experimental tumors, and survival tumor-bearing mice. Cancer Biother. Radiopharm., 2004, 19, 343-349.
    • (2004) Cancer Biother. Radiopharm , vol.19 , pp. 343-349
    • Szende, B.1    Marcsek, Z.2    Kocsis, Z.3    Tompa, A.4
  • 49
    • 0031810683 scopus 로고    scopus 로고
    • Effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals
    • [49] Hidvégi, M.; Ráso, E.; Tömösközi-Farkas, R.; Paku, S.; Lapis, K.; Szende, B. Effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals. Anticancer Res., 1998, 18, 2353-2358.
    • (1998) Anticancer Res , vol.18 , pp. 2353-2358
    • Hidvégi, M.1    Ráso, E.2    Tömösközi-Farkas, R.3    Paku, S.4    Lapis, K.5    Szende, B.6
  • 50
    • 0026775456 scopus 로고
    • Mechanism of antimutagenicity of wheat sprout extracts. Mutat
    • [50] Peryt, B.; Szymczyk, T.; Lesca, P. Mechanism of antimutagenicity of wheat sprout extracts. Mutat. Res., 1992, 269, 201-215.
    • (1992) Res , vol.269 , pp. 201-215
    • Peryt, B.1    Szymczyk, T.2    Lesca, P.3
  • 52
    • 51349133959 scopus 로고    scopus 로고
    • Changes in the kinase expression panel of K562 human leukemia after Avemar treatment
    • [52] Telekes, A.; Rásó, E. Changes in the kinase expression panel of K562 human leukemia after Avemar treatment. J. Clin. Oncol., 2007, 25, 14143.
    • (2007) J. Clin. Oncol , vol.25 , pp. 14143
    • Telekes, A.1    Rásó, E.2
  • 53
    • 0034793642 scopus 로고    scopus 로고
    • AVEMAR (A new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease
    • [53] Ehrenfeld, M.; Blank, M.; Shoenfeld, Y.; Hidvegi, M. AVEMAR (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease. Lupus, 2001, 10, 622-627.
    • (2001) Lupus , vol.10 , pp. 622-627
    • Ehrenfeld, M.1    Blank, M.2    Shoenfeld, Y.3    Hidvegi, M.4
  • 54
    • 84893612241 scopus 로고    scopus 로고
    • Role of Triticum aestivum aqueous extract in glucocorticoid induced osteoporosis in rats
    • [54] Banji, D.; Banji, O.J.; Chiluka, V.L.; Abbagoni, S. Role of Triticum aestivum aqueous extract in glucocorticoid induced osteoporosis in rats. Indian J. Exp. Biol., 2014, 52, 153-158.
    • (2014) Indian J. Exp. Biol , vol.52 , pp. 153-158
    • Banji, D.1    Banji, O.J.2    Chiluka, V.L.3    Abbagoni, S.4
  • 55
    • 77956209014 scopus 로고    scopus 로고
    • Antioxidant effect of Triticum aestivium (Wheat grass) in high-fat diet-induced oxidative stress in rabbits
    • [55] Sethi, J.; Yadav, M.; Dahiya, K.; Sood, S.; Singh, V.; Bhattacharya, S.B. Antioxidant effect of Triticum aestivium (wheat grass) in high-fat diet-induced oxidative stress in rabbits. Methods Find Exp. Clin. Pharmacol., 2010, 32, 233-235.
    • (2010) Methods Find Exp. Clin. Pharmacol , vol.32 , pp. 233-235
    • Sethi, J.1    Yadav, M.2    Dahiya, K.3    Sood, S.4    Singh, V.5    Bhattacharya, S.B.6
  • 56
    • 84901242526 scopus 로고    scopus 로고
    • Biochemical role of fermented wheat germ on liver and kidney functions alteration induced by chlorpyrifos in rats
    • [56] Barakat, H.; Khalil, F.A.; Khalifa, F.K.; Hessin, M.M. Biochemical role of fermented wheat germ on liver and kidney functions alteration induced by chlorpyrifos in rats. Afr. J. Biol. Sci., 2011, 7, 45-60.
    • (2011) Afr. J. Biol. Sci , vol.7 , pp. 45-60
    • Barakat, H.1    Khalil, F.A.2    Khalifa, F.K.3    Hessin, M.M.4
  • 57
    • 84939852218 scopus 로고    scopus 로고
    • Hepatoprotective role of wheatgrass on alcohol and ΔPUFA-induced oxidative stress in rats
    • Apr, [Epub ahead of print]
    • [57] Durairaj, V.; Shakya, G.; Rajagopalan, R. Hepatoprotective role of wheatgrass on alcohol and ΔPUFA-induced oxidative stress in rats. J. Diet Suppl., 2014 Apr 3 [Epub ahead of print].
    • (2014) J. Diet Suppl , vol.3
    • Durairaj, V.1    Shakya, G.2    Rajagopalan, R.3
  • 58
    • 84902281869 scopus 로고    scopus 로고
    • Effect of wheatgrass on membrane fatty acid composition during hepatotoxicity induced by alcohol and heated PUFA
    • [58] Durairaj, V.; Shakya, G.; Pajaniradje, S.; Rajagopalan, R. Effect of wheatgrass on membrane fatty acid composition during hepatotoxicity induced by alcohol and heated PUFA. J. Membr. Biol., 2014, 247, 515-521.
    • (2014) J. Membr. Biol , vol.247 , pp. 515-521
    • Durairaj, V.1    Shakya, G.2    Pajaniradje, S.3    Rajagopalan, R.4
  • 59
    • 79952211179 scopus 로고    scopus 로고
    • Fermented wheat germ extract (Avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats
    • [59] Iyer, A.; Brown, L. Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats. Evid. Based Complement. Alternat. Med., 2011, 2011, 508957.
    • (2011) Evid. Based Complement. Alternat. Med , vol.2011 , pp. 508957
    • Iyer, A.1    Brown, L.2
  • 60
    • 84893798681 scopus 로고    scopus 로고
    • Antidiabetic and antioxidant properties of Triticum aestivum in streptozotocin-induced diabetic rats
    • [60] Mohan, Y.; Jesuthankaraj, G.N.; Ramasamy Thangavelu, N. Antidiabetic and antioxidant properties of Triticum aestivum in streptozotocin-induced diabetic rats. Adv. Pharmacol. Sci., 2013, 2013, 716073.
    • (2013) Adv. Pharmacol. Sci , pp. 2013
    • Mohan, Y.1    Jesuthankaraj, G.N.2    Ramasamy Thangavelu, N.3
  • 61
    • 84971301433 scopus 로고    scopus 로고
    • Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats
    • 0748233714545202[Epub ahead of print]
    • [61] Shakya, G.; Randhi, P.K.; Pajaniradje, S.; Mohankumar, K.; Rajagopalan, R. Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats. Toxicol. Ind. Health, 2014, 2: 0748233714545202. [Epub ahead of print].
    • (2014) Toxicol. Ind. Health , Issue.2
    • Shakya, G.1    Randhi, P.K.2    Pajaniradje, S.3    Mohankumar, K.4    Rajagopalan, R.5
  • 62
    • 85039823229 scopus 로고    scopus 로고
    • Hepatoprotective potential of young leaves of Triticum Aestivum Linn, against CCL4 induced hepatotoxicity
    • [62] Jain, G.; Argal, A. Hepatoprotective potential of young leaves of Triticum Aestivum Linn, against CCL4 induced hepatotoxicity. Int. J. Pharm. Sci. Res., 2014, 5, 4751-4755.
    • (2014) Int. J. Pharm. Sci. Res , vol.5 , pp. 4751-4755
    • Jain, G.1    Argal, A.2
  • 64
    • 51349098875 scopus 로고    scopus 로고
    • Adjuvant fermented wheat germ extract (Avemar) nutraceutical improves survival of high-risk skin melanoma patients: A randomized, pilot, phase II clinical study with a 7-year follow-up. Cancer Biother
    • [64] Demidov, L.V.; Manziuk, L.V.; Kharkevitch, G.Y.; Pirogova, N.A. Artamonova, E.V. Adjuvant fermented wheat germ extract (Avemar) nutraceutical improves survival of high-risk skin melanoma patients: a randomized, pilot, phase II clinical study with a 7-year follow-up. Cancer Biother. Radiopharm., 2008, 23, 477-482.
    • (2008) Radiopharm , vol.23 , pp. 477-482
    • Demidov, L.V.1    Manziuk, L.V.2    Kharkevitch, G.Y.3    Pirogova, N.A.4    Artamonova, E.V.5
  • 66
    • 85013605171 scopus 로고    scopus 로고
    • Multicentric prospective open trial on the quality of life and oxidative stress in patients affected by advanced head and neck cancer treated with a new benzoquinone-rich product derived from fermented wheat germ (Avemar)
    • [66] Sukkar, S.G.; Cella, F.; Rovera, G.M.; Nichelatti, M.; Ragni, G.; Chiavenna, G.; Giannoni, A.; Ronzani, G.; Ferrari, C. A multicentric prospective open trial on the quality of life and oxidative stress in patients affected by advanced head and neck cancer treated with a new benzoquinone-rich product derived from fermented wheat germ (Avemar). Med. J. Nutrition Metab., 2008, 1, 37-42.
    • (2008) Med. J. Nutrition Metab , vol.1 , pp. 37-42
    • Sukkar, S.G.1    Cella, F.2    Rovera, G.M.3    Nichelatti, M.4    Ragni, G.5    Chiavenna, G.6    Giannoni, A.7    Ronzani, G.8    Ferrari, C.A.9
  • 68
    • 0036636094 scopus 로고    scopus 로고
    • Apoptosis as a therapeutic tool in rheumatoid arthritis
    • [68] Pope, R.M. Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat. Rev. Immunol., 2002, 2, 527-535.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 527-535
    • Pope, R.M.1
  • 69
    • 0036210384 scopus 로고    scopus 로고
    • Wheat grass juice in the treatment of active distal ulcerative colitis: A randomized double-blind placebo-controlled trial. Scand
    • [69] Ben-Arye, E.; Goldin, E.; Wengrower, D.; Stamper, A.; Kohn, R.; Berry, E. Wheat grass juice in the treatment of active distal ulcerative colitis: a randomized double-blind placebo-controlled trial. Scand. J. Gastroenterol., 2002, 37, 444-449.
    • (2002) J. Gastroenterol , vol.37 , pp. 444-449
    • Ben-Arye, E.1    Goldin, E.2    Wengrower, D.3    Stamper, A.4    Kohn, R.5    Berry, E.6
  • 70
    • 0035105069 scopus 로고    scopus 로고
    • Antioxidant defense status of red blood cells of patients with beta-thalassemia and Ebetathalassemia
    • [70] Chakraborty, D.; Bhattacharyya, M. Antioxidant defense status of red blood cells of patients with beta-thalassemia and Ebetathalassemia. Clin. Chim. Acta, 2001, 305, 123-129.
    • (2001) Clin. Chim. Acta , vol.305 , pp. 123-129
    • Chakraborty, D.1    Bhattacharyya, M.2
  • 71
    • 84891586833 scopus 로고    scopus 로고
    • Inborn defects in the antioxidant systems of human red blood cells
    • [71] van Zwieten, R.; Verhoeven, A.J; Roos, D. Inborn defects in the antioxidant systems of human red blood cells. Free Radic. Biol. Med., 2014, 67, 377-386.
    • (2014) Free Radic. Biol. Med , vol.67 , pp. 377-386
    • Van Zwieten, R.1    Verhoeven, A.J.2    Roos, D.3
  • 72
    • 3342943276 scopus 로고    scopus 로고
    • Wheat grass juice reduces transfusion requirement in patients with thalassemia major: A pilot study
    • [72] Marwaha, R.K.; Bansal, D.; Kaur, S.; Trehan, A. Wheat grass juice reduces transfusion requirement in patients with thalassemia major: a pilot study. Indian Pediatr., 2004, 41, 716-720.
    • (2004) Indian Pediatr , vol.41 , pp. 716-720
    • Marwaha, R.K.1    Bansal, D.2    Kaur, S.3    Trehan, A.4
  • 73
    • 21244453991 scopus 로고    scopus 로고
    • Natural antioxidant therapy for patients with hemolytic anemia
    • [73] Fernandes, C.J.; O'Donovan, D.J. Natural antioxidant therapy for patients with hemolytic anemia. Indian Pediatr., 2005, 42, 618-620.
    • (2005) Indian Pediatr , vol.42 , pp. 618-620
    • Fernandes, C.J.1    O'donovan, D.J.2
  • 75
    • 76649122206 scopus 로고    scopus 로고
    • Effect of wheat grasstablets on the frequency of blood transfusions in Thalassemia Major. Indian
    • [75] Singh, K.; Pannu, M.S.; Singh, P.; Singh, J. Effect of wheat grasstablets on the frequency of blood transfusions in Thalassemia Major. Indian J. Pediatr., 2010, 77, 90-91.
    • (2010) J. Pediatr , vol.77 , pp. 90-91
    • Singh, K.1    Pannu, M.S.2    Singh, P.3    Singh, J.4
  • 76
    • 84855473441 scopus 로고    scopus 로고
    • The role of iron chelation activity of wheat grass juice in patients with myelodysplastic syndrome
    • [Abstract 10046, 2009 ASCO Annual meeting]
    • [76] Mukhopadhyay, S.; Basak, J.; Kar, M.; Mandal, S.; Mukhopadhyay, A. The role of iron chelation activity of wheat grass juice in patients with myelodysplastic syndrome. J. Clin. Oncol., 2009, 7012. [Abstract 10046, 2009 ASCO Annual meeting]
    • (2009) J. Clin. Oncol , pp. 7012
    • Mukhopadhyay, S.1    Basak, J.2    Kar, M.3    Mandal, S.4    Mukhopadhyay, A.5
  • 77
    • 84939852220 scopus 로고    scopus 로고
    • Haripriya, S. Effect of supplementation of wheat germ, wheat bran and wheat grass to subjects with specific health issues
    • F33-439/2007(SR), Department of Food Science and Nutrition, Avinashilingam University for Women, Coimbatore, India
    • [77] Premakumari, S.; Haripriya, S. Effect of supplementation of wheat germ, wheat bran and wheat grass to subjects with specific health issues. UGC Minor Research Project no. F33-439/2007(SR). 2010. Department of Food Science and Nutrition, Avinashilingam University for Women, Coimbatore, India.
    • (2010) UGC Minor Research Project No
    • Premakumari, S.1
  • 78
    • 35948989236 scopus 로고    scopus 로고
    • Wheat grass supplementation decreases oxidative stress in healthy subjects: A comparative study with spirulina
    • [78] Shyam, R.; Singh, S.N.; Vats, P.; Singh, V.K.; Bajaj, R.; Singh, S.B.; Banerjee, PK. Wheat grass supplementation decreases oxidative stress in healthy subjects: a comparative study with spirulina. J. Altern. Complement. Med., 2007, 13, 789-791.
    • (2007) J. Altern. Complement. Med , vol.13 , pp. 789-791
    • Shyam, R.1    Singh, S.N.2    Vats, P.3    Singh, V.K.4    Bajaj, R.5    Singh, S.B.6    Banerjee, P.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.