Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats

Toxicology and Industrial Health

Volumn 32, Issue 6, 2016, Pages 1026-1032

  Shakya, Garima ^a   Randhi, Praveen Kumar ^a   Pajaniradje, Sankar ^a   Mohankumar, Kumaravel ^a   Rajagopalan, Rukkumani ^a  

^a PONDICHERRY UNIVERSITY   (India)

Author keywords

G6PD; glucose; hexokinase; Type II diabetes mellitus; wheatgrass

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE OXIDATIVE ENZYME; GLYCOGEN; HEXOKINASE; INSULIN; OXIDOREDUCTASE; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; PLANT MEDICINAL PRODUCT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIETARY SUPPLEMENT; FLUID INTAKE; FOOD INTAKE; GLYCOGEN LIVER LEVEL; GRASS; INSULIN BLOOD LEVEL; LIVER LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; RAT; TRADITIONAL MEDICINE; WEIGHT GAIN; WHEATGRASS; ANIMAL; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; LIVER; METABOLISM; PROGNOSIS; WHEAT; WISTAR RAT;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; GLUCOSEPHOSPHATE DEHYDROGENASE; HEXOKINASE; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; LIVER GLYCOGEN; MALE; PLANT PREPARATIONS; PROGNOSIS; RATS; RATS, WISTAR; TRITICUM;

EID: 84971301433     PISSN: 07482337     EISSN: 14770393     Source Type: Journal    
DOI: 10.1177/0748233714545202     Document Type: Article

References (26)

1. Anderson WB, Nordlie RC, (1968) Glucose dehydrogenase activity of yeast glucose-6-phosphate dehydrogenase I selective stimulation by bicarbonate, phosphate and sulphate. Biochemistry 7 (4): 1479-1485.
2. Arora S, Kumar Ojha S, Vohora D, (2009) Characterization of streptozotocin induced diabetes mellitus in swiss albino mice. Global Journal of Pharmacology 3 (2): 81-84.
3. Aydos OS, Avci A, Ozkan T, et al. (2011) Antiproliferative, apoptotic and antioxidant activities of wheatgrass (Triticum aestivum L.) extract on CML (K562) cell line. Turkish Journal of Medical Sciences 41 (4): 657-663.
4. Balasubashini MS, Rukkumani R, Menon VP, (2003) Protective effects of ferulic acid on hyperlipidemic diabetic rats. Acta Diabetologica 40 (3): 118-122.
5. Balasubashini MS, Rukkumani R, Viswanathan P, et al. (2004) Ferulic acid alleviates lipid peroxidation in diabetic rats. Phytotherapy Research 18 (4): 310-314.
6. Coburn HJ, Carrol JJ, (1973) Improved manual and automated colorimetric determination of serum glucose, with use of hexokinase and glucose-6-phosphate dehydrogenase. Clinical Chemistry 19 (1): 127-130.
7. Dorfmeister B, Cooper JA, Stephens JW, et al. (2007) The effects of APOA5 and APOC3 variants on lipid parameters in European whites, Indian Asians and Afro-Caribbeans with type 2 diabetes. Biochimica et Biophysica Acta 1772 (3): 355-363.
8. Dubowski KM, (1962) An o-Toluidine method for body-fluid glucose determination. Clinical Chemistry 8: 215-235.
9. Fonseca V, (2006) The role of basal insulin therapy in patients with type 2 diabetes mellitus. Insulin 1 (2): 51-60.
10. Gandhi GR, Ignacimuthu S, Paulraj MG, (2011) Solanum torvum Swartz. fruit containing phenolic compounds shows 3 antidiabetic and antioxidant effects in streptozotocin induced diabetic rats. Food and Chemical Toxicology 49 (11): 2725-2733.
11. Gastaldelli A, (2011) Role of beta-cell dysfunction, ectopic fat accumulation and insulin resistance in the pathogenesis of type 2 diabetes mellitus. Diabetes Research and clinical practice 93 (1): S60-S65.
12. Ito M, Kondo Y, Nakatani A, et al. (2001) Characterization of low dose streptozotocin-induced progressive diabetes in mice. Environmental Toxicology and Pharmacology 9 (3): 71-78.
13. Kulkarni SD, Tilak JC, Acharya R, et al. (2006) Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions. Phytotherapy Research 20 (3): 218-227.
14. Li G, Hu Y, Yang W, et al. (2002) Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus: The DA Qing IGT and diabetes study. Diabetes Research and Clinical Practice 58 (3): 193-200.
15. Moreira ED Jr., Neves SRC, Nunes ZO, et al. (2010) Glycemic control and its correlates in patients with diabetes in venezuela: results from a nationwide survey. Diabetes Research and Clinical Practice 87 (3): 407-414.
16. Olivares-Reyes JA, Arellano-Plancarte A, Castillo-Hernandez JR, (2009) Angiotensin II and the development of insulin resistance: implications for diabetes. Molecular and Cellular Endocrinology 302 (2): 128-139.
17. Ozer N, Aksoy Y, Ogus IH, (2001) Kinetic properties of human placental glucose-6-phosphate dehydrogenase. The International Journal of Biochemistry & Cell Biology 33 (3): 221-226.
18. Pugazhenthi S, Khandelwal RL, Angel JF, (1991) Insulin-like effect of vanadate on malic enzyme and glucose-6-phosphate dehydrogenase activities in streptozotocin-induced diabetic rat liver. Biochimica et Biophysica Acta 1 083 (3): 310-312.
19. Ramkumar KM, Rajaguru P, Latha M, et al. (2007) Ethanol extract of Gymnema montanum leaves reduces glycoprotein components in experimental diabetes. Nutrition Research 27 (2): 97-103.
20. Saravanan G, Ponmurugan P, (2011) Ameliorative potential of S-Allylcysteine: effect on lipid profile and changes in tissue fatty acid composition in experimental diabetes. Experimental and Toxicologic Pathology 64 (6): 639-644.
21. Seifter S, Dayton S, Novic B, et al. (1950) Estimation of glycogen with anthrone reagent. Archives of Biochemistry and Biophysics 25 (1): 191-200.
22. Seki Y, Sato K, Akiba Y, (2005) Changes in muscle mRNAs for hexokinase, phosphofructokinase-1 and glycogen synthase in acute and persistent hypoglycemia induced by tolbutamide in chickens. Comparative Biochemistry and Physiology, Part B 142 (2): 201-208.
23. Sharma B, Balomajumder C, Roy P, (2008) Hypoglycemic and hypolipidemic effects of flavonoid rich extract from Eugenia jambolana seeds on streptozotocin induced diabetic rats. Food and Chemical Toxicology 46 (7): 2376-2383.
24. Sri Jaya M, Gayathri S, (2009) Antioxidant activity of wheatgrass and impact of supplementing grass extract on anaemics. Biomedicine 4 (3): 262-268.
25. Tian HL, Wei LS, Xu ZX, et al. (2010) Correlation between blood glucose and diabetes signs in streptozotocin induced diabetic mice. Global Journal of Pharmacology 4 (3): 111-116.
26. Yalow RS, Berson SA, (1960) Immunoassay of endogenous plasma insulin in man. Journal of Clinical Investigation 39 (7): 1157-1175.