메뉴 건너뛰기




Volumn 6, Issue 8, 2015, Pages 1420-1427

Gender Differences in Spatial Learning, Synaptic Activity, and Long-Term Potentiation in the Hippocampus in Rats: Molecular Mechanisms

Author keywords

AMPA receptor; cGMP; cGMP dependent protein kinase; GluR1

Indexed keywords

AMPA RECEPTOR; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GUANYLATE CYCLASE; 4 AMINOBUTYRIC ACID RECEPTOR; METABOTROPIC RECEPTOR;

EID: 84939806896     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.5b00096     Document Type: Article
Times cited : (58)

References (49)
  • 1
    • 0029974313 scopus 로고    scopus 로고
    • Sex, sexual orientation and sex hormones influence human cognitive function
    • Kimura, D. (1996) Sex, sexual orientation and sex hormones influence human cognitive function Curr. Opin Neurobiol. 6 (2) 259-263
    • (1996) Curr. Opin Neurobiol. , vol.6 , Issue.2 , pp. 259-263
    • Kimura, D.1
  • 2
    • 33645128574 scopus 로고    scopus 로고
    • Males and females differ in brain activation during cognitive tasks
    • Bell, E. C., Willson, M. C., Wilman, A. H., Dave, S., and Silverstone, P. H. (2006) Males and females differ in brain activation during cognitive tasks Neuroimage 30 (2) 529-538
    • (2006) Neuroimage , vol.30 , Issue.2 , pp. 529-538
    • Bell, E.C.1    Willson, M.C.2    Wilman, A.H.3    Dave, S.4    Silverstone, P.H.5
  • 3
    • 13544267181 scopus 로고    scopus 로고
    • Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation
    • Astur, R. S., Tropp, J., Sava, S., Constable, R. T., and Markus, E. J. (2004) Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation Behav. Brain Res. 151 (1-2) 103-115
    • (2004) Behav. Brain Res. , vol.151 , Issue.12 , pp. 103-115
    • Astur, R.S.1    Tropp, J.2    Sava, S.3    Constable, R.T.4    Markus, E.J.5
  • 4
    • 77249116306 scopus 로고    scopus 로고
    • Sex differences in human virtual water maze performance: Novel measures reveal the relative contribution of directional responding and spatial knowledge
    • Woolley, D. G., Vermaercke, B., Op de Beeck, H., Wagemans, J., Gantois, I., DHooge, R., Swinnen, S. P., and Wenderoth, N. (2010) Sex differences in human virtual water maze performance: novel measures reveal the relative contribution of directional responding and spatial knowledge Behav. Brain Res. 208 (2) 408-414
    • (2010) Behav. Brain Res. , vol.208 , Issue.2 , pp. 408-414
    • Woolley, D.G.1    Vermaercke, B.2    Op De Beeck, H.3    Wagemans, J.4    Gantois, I.5    Dhooge, R.6    Swinnen, S.P.7    Wenderoth, N.8
  • 5
    • 84155188942 scopus 로고    scopus 로고
    • Eye tracking, strategies, and sex differences in virtual navigation
    • Andersen, N. E., Dahmani, L., Konishi, K., and Bohbot, V. D. (2012) Eye tracking, strategies, and sex differences in virtual navigation Neurobiol. Learn. Mem. 97 (1) 81-89
    • (2012) Neurobiol. Learn. Mem. , vol.97 , Issue.1 , pp. 81-89
    • Andersen, N.E.1    Dahmani, L.2    Konishi, K.3    Bohbot, V.D.4
  • 6
    • 12144257804 scopus 로고    scopus 로고
    • Meta-analysis of sex differences in rodent models of learning and memory: A review of behavioral and biological data
    • Jonasson, Z. (2005) Meta-analysis of sex differences in rodent models of learning and memory: a review of behavioral and biological data Neurosci. Biobehav. Rev. 28 (8) 811-825
    • (2005) Neurosci. Biobehav. Rev. , vol.28 , Issue.8 , pp. 811-825
    • Jonasson, Z.1
  • 7
    • 36749050227 scopus 로고    scopus 로고
    • Sex differences in object location memory and spatial navigation in Long-Evans rats
    • Saucier, D. M., Shultz, S. R., Keller, A. J., Cook, C. M., and Binsted, G. (2008) Sex differences in object location memory and spatial navigation in Long-Evans rats Anim. Cogn. 11 (1) 129-137
    • (2008) Anim. Cogn. , vol.11 , Issue.1 , pp. 129-137
    • Saucier, D.M.1    Shultz, S.R.2    Keller, A.J.3    Cook, C.M.4    Binsted, G.5
  • 8
    • 67650383429 scopus 로고    scopus 로고
    • Spatial working memory learning in young male and female rats: Involvement of different limbic system regions revealed by cytochrome oxidase activity
    • Méndez-López, M., Méndez, M., López, L., and Arias, J. L. (2009) Spatial working memory learning in young male and female rats: involvement of different limbic system regions revealed by cytochrome oxidase activity Neurosci. Res. 65 (1) 28-34
    • (2009) Neurosci. Res. , vol.65 , Issue.1 , pp. 28-34
    • Méndez-López, M.1    Méndez, M.2    López, L.3    Arias, J.L.4
  • 9
    • 3242773378 scopus 로고    scopus 로고
    • Contribution of sex differences in the acute stress response to sex differences in water maze performance in the rat
    • Beiko, J., Lander, R., Hampson, E., Boon, F., and Cain, D. P. (2004) Contribution of sex differences in the acute stress response to sex differences in water maze performance in the rat Behav. Brain Res. 151 (1-2) 239-253
    • (2004) Behav. Brain Res. , vol.151 , Issue.12 , pp. 239-253
    • Beiko, J.1    Lander, R.2    Hampson, E.3    Boon, F.4    Cain, D.P.5
  • 10
    • 83455260389 scopus 로고    scopus 로고
    • The effects of biological sex and gonadal hormones on learning strategy in adult rats
    • Hawley, W. R., Grissom, E. M., Barratt, H. E., Conrad, T. S., and Dohanich, G. P. (2012) The effects of biological sex and gonadal hormones on learning strategy in adult rats Physiol. Behav. 105 (4) 1014-1020
    • (2012) Physiol. Behav. , vol.105 , Issue.4 , pp. 1014-1020
    • Hawley, W.R.1    Grissom, E.M.2    Barratt, H.E.3    Conrad, T.S.4    Dohanich, G.P.5
  • 11
    • 0019450078 scopus 로고
    • Spatial memory following damage to hippocampal CA3 pyramidal cells with kainic acid: Impairment and recovery with preoperative training
    • Handelmann, G. E. and Olton, D. S. (1981) Spatial memory following damage to hippocampal CA3 pyramidal cells with kainic acid: impairment and recovery with preoperative training Brain Res. 217 (1) 41-58
    • (1981) Brain Res. , vol.217 , Issue.1 , pp. 41-58
    • Handelmann, G.E.1    Olton, D.S.2
  • 12
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris, R. G., Garrud, P., Rawlins, J. N., and OKeefe, J. (1982) Place navigation impaired in rats with hippocampal lesions Nature 297 (5868) 681-683
    • (1982) Nature , vol.297 , Issue.5868 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    Okeefe, J.4
  • 13
    • 0037089803 scopus 로고    scopus 로고
    • Humans with hippocampus damage display severe spatial memory impairments in a virtual Morris water task
    • Astur, R. S., Taylor, L. B., Mamelak, A. N., Philpott, L., and Sutherland, R. J. (2002) Humans with hippocampus damage display severe spatial memory impairments in a virtual Morris water task Behav. Brain Res. 132 (1) 77-84
    • (2002) Behav. Brain Res. , vol.132 , Issue.1 , pp. 77-84
    • Astur, R.S.1    Taylor, L.B.2    Mamelak, A.N.3    Philpott, L.4    Sutherland, R.J.5
  • 14
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss, T. V. P. and Collingridge, G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus Nature 361, 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 16
    • 0031590452 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity: Role in spatial learning or the automatic recording of attended experience?
    • Morris, R. G. and Frey, U. (1997) Hippocampal synaptic plasticity: role in spatial learning or the automatic recording of attended experience? Philos. Trans. R. Soc., B 352 (1360) 1489-1503
    • (1997) Philos. Trans. R. Soc., B , vol.352 , Issue.1360 , pp. 1489-1503
    • Morris, R.G.1    Frey, U.2
  • 17
    • 0024393433 scopus 로고
    • An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
    • Malenka, R. C., Kauer, J. A., Perkel, D. J., Mauk, M. D., Kelly, P. T., Nicoll, R. A., and Waxham, M. N. (1989) An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation Nature 340, 554-557
    • (1989) Nature , vol.340 , pp. 554-557
    • Malenka, R.C.1    Kauer, J.A.2    Perkel, D.J.3    Mauk, M.D.4    Kelly, P.T.5    Nicoll, R.A.6    Waxham, M.N.7
  • 18
    • 0030664827 scopus 로고    scopus 로고
    • Activation of NMDA receptors is necessary for the induction of associative long-term potentiation in area CA1 of the rat hippocampal slice
    • Murphy, K. P., Reid, G. P., Trentham, D. R., and Bliss, T. V. (1997) Activation of NMDA receptors is necessary for the induction of associative long-term potentiation in area CA1 of the rat hippocampal slice J. Physiol. 504, 379-385
    • (1997) J. Physiol. , vol.504 , pp. 379-385
    • Murphy, K.P.1    Reid, G.P.2    Trentham, D.R.3    Bliss, T.V.4
  • 19
    • 0034708587 scopus 로고    scopus 로고
    • Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction
    • Hayashi, Y., Shi, S. H., Esteban, J. A., Piccini, A., Poncer, J. C., and Malinow, R. (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction Science 287, 2262-2267
    • (2000) Science , vol.287 , pp. 2262-2267
    • Hayashi, Y.1    Shi, S.H.2    Esteban, J.A.3    Piccini, A.4    Poncer, J.C.5    Malinow, R.6
  • 20
    • 0033546052 scopus 로고    scopus 로고
    • Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation
    • Shi, S. H., Hayashi, Y., Petralia, R. S., Zaman, S. H., Wenthold, R. J., Svoboda, K., and Malinow, R. (1999) Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation Science 284, 1755-1757
    • (1999) Science , vol.284 , pp. 1755-1757
    • Shi, S.H.1    Hayashi, Y.2    Petralia, R.S.3    Zaman, S.H.4    Wenthold, R.J.5    Svoboda, K.6    Malinow, R.7
  • 21
    • 0034330386 scopus 로고    scopus 로고
    • Postsynaptic organization and regulation of excitatory synapses
    • Scannevin, R. H. and Huganir, R. L. (2000) Postsynaptic organization and regulation of excitatory synapses Nat. Rev. Neurosci. 1, 133-141
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 133-141
    • Scannevin, R.H.1    Huganir, R.L.2
  • 22
    • 0035132869 scopus 로고    scopus 로고
    • Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
    • Lu, W., Man, H., Ju, W., Trimble, W. S., MacDonald, J. F., and Wang, Y. T. (2001) Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons Neuron 29, 243-254
    • (2001) Neuron , vol.29 , pp. 243-254
    • Lu, W.1    Man, H.2    Ju, W.3    Trimble, W.S.4    MacDonald, J.F.5    Wang, Y.T.6
  • 23
    • 0037312605 scopus 로고    scopus 로고
    • PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
    • Esteban, J. A., Shi, S. H., Wilson, C., Nuriya, M., Huganir, R. L., and Malinow, R. (2003) PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity Nat. Neurosci. 6, 136-143
    • (2003) Nat. Neurosci. , vol.6 , pp. 136-143
    • Esteban, J.A.1    Shi, S.H.2    Wilson, C.3    Nuriya, M.4    Huganir, R.L.5    Malinow, R.6
  • 25
    • 33644851262 scopus 로고    scopus 로고
    • Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiation
    • Oh, M. C., Derkach, V. A., Guire, E. S., and Soderling, T. R. (2006) Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiation J. Biol. Chem. 281, 752-758
    • (2006) J. Biol. Chem. , vol.281 , pp. 752-758
    • Oh, M.C.1    Derkach, V.A.2    Guire, E.S.3    Soderling, T.R.4
  • 26
    • 0036895966 scopus 로고    scopus 로고
    • Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase, and cGMP-degrading phosphodiesterase
    • Monfort, P., Muñoz, M. D., and Kosenko, E. et al. 2002, Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase, and cGMP-degrading phosphodiesterase J. Neurosci. 22, 10116-10122
    • (2002) J. Neurosci. , vol.22 , pp. 10116-10122
    • Monfort, P.1    Muñoz, M.D.2    Kosenko, E.3
  • 28
    • 34248682107 scopus 로고    scopus 로고
    • Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase, alterations in hyperammonemia
    • Monfort, P. and Felipo, V. (2005) Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase, alterations in hyperammonemia BMC Pharmacol. 5 (Suppl 1) P66
    • (2005) BMC Pharmacol. , vol.5 , pp. 66
    • Monfort, P.1    Felipo, V.2
  • 29
    • 0034672306 scopus 로고    scopus 로고
    • The AMPAR subunit GluR2: Still front and center-stage
    • Tanaka, H., Grooms, S. Y., Bennett, M. V., and Zukin, R. S. (2000) The AMPAR subunit GluR2: still front and center-stage Brain Res. 886, 190-207
    • (2000) Brain Res. , vol.886 , pp. 190-207
    • Tanaka, H.1    Grooms, S.Y.2    Bennett, M.V.3    Zukin, R.S.4
  • 31
    • 58149151430 scopus 로고    scopus 로고
    • Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking
    • Famous, K. R., Kumaresan, V., Sadri-Vakili, G., Schmidt, H. D., Mierke, D. F., Cha, J. H., and Pierce, R. C. (2008) Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking J. Neurosci. 28, 11061-11070
    • (2008) J. Neurosci. , vol.28 , pp. 11061-11070
    • Famous, K.R.1    Kumaresan, V.2    Sadri-Vakili, G.3    Schmidt, H.D.4    Mierke, D.F.5    Cha, J.H.6    Pierce, R.C.7
  • 32
    • 44649125940 scopus 로고    scopus 로고
    • Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons
    • States, B. A., Khatri, L., and Ziff, E. B. (2008) Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons Mol. Cell Neurosci. 38, 189-202
    • (2008) Mol. Cell Neurosci. , vol.38 , pp. 189-202
    • States, B.A.1    Khatri, L.2    Ziff, E.B.3
  • 33
    • 34247193729 scopus 로고    scopus 로고
    • Hippocampal long-term potentiation is reduced in mature compared to young male rats but not in female rats
    • Monfort, P. and Felipo, V. (2007) Hippocampal long-term potentiation is reduced in mature compared to young male rats but not in female rats Neuroscience 146, 504-508
    • (2007) Neuroscience , vol.146 , pp. 504-508
    • Monfort, P.1    Felipo, V.2
  • 34
    • 57249086446 scopus 로고    scopus 로고
    • Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking
    • Liu, Y., Sun, Q. A., Chen, Q., Lee, T. H., Huang, Y., Wetsel, W. C., Michelotti, G. A., Sullenger, B. A., and Zhang, X. (2009) Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking J. Neurochem. 108 (1) 147-157
    • (2009) J. Neurochem. , vol.108 , Issue.1 , pp. 147-157
    • Liu, Y.1    Sun, Q.A.2    Chen, Q.3    Lee, T.H.4    Huang, Y.5    Wetsel, W.C.6    Michelotti, G.A.7    Sullenger, B.A.8    Zhang, X.9
  • 35
    • 69349099799 scopus 로고    scopus 로고
    • Transport of AMPA receptors during long-term potentiation is impaired in rats with hepatic encephalopathy
    • Monfort, P., Piedrafita, B., and Felipo, V. (2009) Transport of AMPA receptors during long-term potentiation is impaired in rats with hepatic encephalopathy Neurochem. Int. 55, 514-520
    • (2009) Neurochem. Int. , vol.55 , pp. 514-520
    • Monfort, P.1    Piedrafita, B.2    Felipo, V.3
  • 36
    • 0030175899 scopus 로고    scopus 로고
    • Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit
    • Roche, K. W., OBrien, R. J., Mammen, A. L., Bernhardt, J., and Huganir, R. L. (1996) Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit Neuron 16, 1179-1188
    • (1996) Neuron , vol.16 , pp. 1179-1188
    • Roche, K.W.1    Obrien, R.J.2    Mammen, A.L.3    Bernhardt, J.4    Huganir, R.L.5
  • 37
    • 74049162430 scopus 로고    scopus 로고
    • Specific roles of AMPA receptor subunit GluR1 (GluA1) phosphorylation sites in regulating synaptic plasticity in the CA1 region of hippocampus
    • Lee, H. K., Takamiya, K., He, K., Song, L., and Huganir, R. L. (2010) Specific roles of AMPA receptor subunit GluR1 (GluA1) phosphorylation sites in regulating synaptic plasticity in the CA1 region of hippocampus J. Neurophysiol. 103, 479-489
    • (2010) J. Neurophysiol. , vol.103 , pp. 479-489
    • Lee, H.K.1    Takamiya, K.2    He, K.3    Song, L.4    Huganir, R.L.5
  • 38
    • 0028275855 scopus 로고
    • Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
    • Zhuo, M., Hu, Y., Schultz, C., Kandel, E. R., and Hawkins, R. D. (1994) Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation Nature 368, 635-639
    • (1994) Nature , vol.368 , pp. 635-639
    • Zhuo, M.1    Hu, Y.2    Schultz, C.3    Kandel, E.R.4    Hawkins, R.D.5
  • 39
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris, R. G., Anderson, E., Lynch, G. S., and Baudry, M. (1986) Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5 Nature 319 (6056) 774-776
    • (1986) Nature , vol.319 , Issue.6056 , pp. 774-776
    • Morris, R.G.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 40
    • 0038561176 scopus 로고    scopus 로고
    • Elements of a neurobiological theory of the hippocampus: The role of activity-dependent synaptic plasticity in memory
    • Morris, R. G., Moser, E. I., Riedel, G., Martin, S. J., Sandin, J., Day, M., and OCarroll, C. (2003) Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory Philos. Trans. R. Soc., B 358 (1432) 773-786
    • (2003) Philos. Trans. R. Soc., B , vol.358 , Issue.1432 , pp. 773-786
    • Morris, R.G.1    Moser, E.I.2    Riedel, G.3    Martin, S.J.4    Sandin, J.5    Day, M.6    Ocarroll, C.7
  • 41
    • 0346728801 scopus 로고    scopus 로고
    • Long-term potentiation and memory
    • Lynch, M. A. (2004) Long-term potentiation and memory Physiol Rev. 84 (1) 87-136
    • (2004) Physiol Rev. , vol.84 , Issue.1 , pp. 87-136
    • Lynch, M.A.1
  • 42
    • 44549084598 scopus 로고    scopus 로고
    • A role for the spine apparatus in LTP and spatial learning
    • Jedlicka, P., Vlachos, A., Schwarzacher, S. W., and Deller, T. (2008) A role for the spine apparatus in LTP and spatial learning Behav. Brain Res. 192 (1) 12-19
    • (2008) Behav. Brain Res. , vol.192 , Issue.1 , pp. 12-19
    • Jedlicka, P.1    Vlachos, A.2    Schwarzacher, S.W.3    Deller, T.4
  • 44
    • 34147206367 scopus 로고    scopus 로고
    • Chronic liver failure in rats impairs glutamatergic synaptic transmission and long-term potentiation in hippocampus and learning ability
    • Monfort, P., Erceg, S., Piedrafita, B., Llansola, M., and Felipo, V. (2007) Chronic liver failure in rats impairs glutamatergic synaptic transmission and long-term potentiation in hippocampus and learning ability Eur. J. Neurosci. 25, 2103-2111
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 2103-2111
    • Monfort, P.1    Erceg, S.2    Piedrafita, B.3    Llansola, M.4    Felipo, V.5
  • 46
    • 0342313714 scopus 로고    scopus 로고
    • Hyperammonemia impairs NMDA receptor-dependent long-term potentiation in the CA1 of rat hippocampus in vitro
    • Muñoz, M. D., Monfort, P., Gaztelu, J. M., and Felipo, V. (2000) Hyperammonemia impairs NMDA receptor-dependent long-term potentiation in the CA1 of rat hippocampus in vitro Neurochem. Res. 25, 437-441
    • (2000) Neurochem. Res. , vol.25 , pp. 437-441
    • Muñoz, M.D.1    Monfort, P.2    Gaztelu, J.M.3    Felipo, V.4
  • 47
    • 2942586826 scopus 로고    scopus 로고
    • Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism
    • Picconi, B., Gardoni, F., Centonze, D., Mauceri, D., Cenci, M. A., Bernardi, G., Calabresi, P., and Di Luca, M. (2004) Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism J. Neurosci. 24, 5283-5291
    • (2004) J. Neurosci. , vol.24 , pp. 5283-5291
    • Picconi, B.1    Gardoni, F.2    Centonze, D.3    Mauceri, D.4    Cenci, M.A.5    Bernardi, G.6    Calabresi, P.7    Di Luca, M.8
  • 48
    • 0035282948 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity involves competition between Ca2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor
    • Gardoni, F., Schrama, L. H., Kamal, A., Gispen, W. H., Cattabeni, F., and Di Luca, M. G. (2001) Hippocampal synaptic plasticity involves competition between Ca2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor J. Neurosci. 21 (5) 1501-1509
    • (2001) J. Neurosci. , vol.21 , Issue.5 , pp. 1501-1509
    • Gardoni, F.1    Schrama, L.H.2    Kamal, A.3    Gispen, W.H.4    Cattabeni, F.5    Di Luca, M.G.6
  • 49
    • 0035799999 scopus 로고    scopus 로고
    • Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis
    • Monfort, P., Corbalán, R., Martinez, L., López-Talavera, J. C., Córdoba, J., and Felipo, V. (2001) Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis Neuroscience 104, 1119-1125
    • (2001) Neuroscience , vol.104 , pp. 1119-1125
    • Monfort, P.1    Corbalán, R.2    Martinez, L.3    López-Talavera, J.C.4    Córdoba, J.5    Felipo, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.