Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17399-17407

  Hamilton, Brian S ^a   Whittaker, Gary R ^a  

^a Department of Microbiology and Immunology College of Veterinary Medicine Cornell University Ithaca New York 14853 USA New York Center of Excellence for Influenza Research and Surveillance University of Rochester Medical Center Rochester New York 14627 USA ^*

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE EFFICIENCY; CLEAVAGE SITES; CRITICAL STEPS; HUMAN RESPIRATORY TRACT; INFLUENZA VIRUS; PEPTIDE MIMICS; PLASMA KALLIKREIN; POTENT ACTIVATORS;

AMINO ACIDS; VIRUSES;

CHEMICAL ACTIVATION;

ARGININE; ENZYME PRECURSOR; KALLIKREIN 5; KALLIKREIN RELATED PEPTIDASE 12; PLASMINOGEN; UNCLASSIFIED DRUG; UROKINASE; VIRUS ENZYME;

ADULT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME RELEASE; HUMAN; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H2N2; INFLUENZA VIRUS A H3N2; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS ACTIVATION; VIRUS REPLICATION; VIRUS STRAIN;

HEMAGGLUTININ; INFLUENZA VIRUS; KALLIKREIN; MEMBRANE FUSION; PROTEASE; SERINE PROTEASE;

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; DOGS; ENZYME ACTIVATION; ENZYME PRECURSORS; FIBRINOLYSIN; HEK293 CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; KALLIKREINS; KINETICS; NASAL LAVAGE FLUID; NOSE; PEPTIDE FRAGMENTS; PROTEOLYSIS; SUBSTRATE SPECIFICITY; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; VERO CELLS;

BACTERIA (MICROORGANISMS); ORTHOMYXOVIRIDAE;

EID: 84879065012     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.440362     Document Type: Article

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