Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: Amino acid sequence at the HA cleavage site as a marker of pathogenicity potential

Avian Diseases

Volumn 40, Issue 2, 1996, Pages 425-437

  Senne, D A ^a,e   Panigrahy, B ^b   Kawaoka, Y ^b   Pearson, J E ^c   Suss, J ^a,c   Lipkind, M ^d   Kida, H ^d   Webster, R G ^d  

^a National Veterinary Services Laboratories   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c Federal Institute for Health Protection of Consumers and Veterinary Medicine   (Germany)

^d KIMRON VETERINARY INSTITUTE   (Israel)

^e HOKKAIDO UNIVERSITY   (Japan)

Author keywords

amino acid sequence; avian influenza; reverse transcription polymerase chain reaction

Indexed keywords

ANIMALIA; AVES; AVIAN INFLUENZA VIRUS; GALLUS GALLUS; INFLUENZA VIRUS; INFLUENZAVIRUS A; LEIOTHRIX LUTEA;

EID: 0030128742     PISSN: 00052086     EISSN: None     Source Type: Journal    
DOI: 10.2307/1592241     Document Type: Article

References (30)

1. Barr, P. J. Mammalian subtilisins: the long sought dibasic processing endoproteases. Cell 66(1) 1-3. 1991.
2. Bean, W. J., G. Sriram, and R. G. Webster Electrophoretic analysis of iodine-labeled influenza virus RNA segments. Anal. Biochem. 102:228-232 1983.
3. Beard, C. W. Serologie procedures. In: A lab oratory manual for the isolation and identification o avian pathogens, 3rd ed. H. G. Purchase, L. H. Arp C. H. Domermuth, and J. E. Pearson, eds. America: Association of Avian Pathologists. pp. 192-200. 1989.
4. Bosch, F. X., M. Orlich, H.-D. Klenk, and R. Rott. The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses. Virology 95:197-207. 1979.
5. Bosch, F. X., W. Garten, H.-D. Klenk, and R. Rott. Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of avian influenza virus. Virology 113:725-735. 1981.
6. De, B. K., G. G. Brownlee, A. P. Kendal, and M. W. Shaw. Complete sequence of a cDNA clone of the haemagglutinin gene of A/chicken/Scotland/ 59 (H5N1) virus: comparison with contemporary North American and European strains. Nucleic Acids Res. 1:4181-4182. 1988.
7. Easterday, B. C. Report of the panel on development of uniform identification and terminology of avian influenza viruses. Proc. 1st Int. Symp. Avian Influenza, Beltsville, Maryland, p. viii. 1981.
8. Fichtner, G. The Pennsylvania/Virginia experience in eradication of avian influenza (H5N2). Proc. 2nd Int. Symp. Avian Influenza, Athens, Georgia, pp. 33-38. 1986.
9. Günther, L, B. Glatthaar, G. Döller, and W. Garten. A Hl hemagglutinin of a human influenza A virus with a carbohydrate-modulated receptor binding site and an unusual cleavage site. Virus Res. 27:147-160. 1993.
10. Horimoto, T., K. Nakayama, S. P. Smeekens, and Y. Kawaoka. Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses. J. Virol. 68(9):60746078. 1994.
11. Katz, J. M., W. Maoliang, and R. G. Webster. Direct sequencing of the HA gene of influenza (H3N2) virus in original clinical samples reveals sequence identity with mammalian cell-grown virus. J. Virol. 64:1808-1811. 1990.
12. Kawaoka, Y., C. W. Naeve, and R. G. Webster. Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin? Virology 139:303-316. 1984.
13. Kawaoka, Y., A. Nestorowicz, D. J. Alexander, and R. G. Webster. Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain. Virology 158:218-227. 1987.
14. Kawaoka, Y., and Robert G. Webster. Sequence requirement for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells. Proc. Nad. Acad. Sei. USA 85:324-328. 1988.
15. Kawaoka, Y., S. Yamnikova, T. M. Chambers, D. K. Lvov, and R. G. Webster. Molecular characterization of a new hemagglutinin, subtype H14, of influenza A virus. Virology 179:759-767. 1990.
16. Lipkind, M., and Y. Weisman. Ecological studies and diagnosis of animal influenza and paramyxoviruses in Israel. II. Animal influenza: a review on decade studies. Isr. J. Vet. Med. 45(4):263-287. 1989.
17. McCapes, R. H. Report of the committee on transmissible diseases of poultry and other avian species. Proc. 91st Annu. Meeting, USAHA, Salt Lake City, Utah, pp. 374-398. 1987.
18. McCauley, J. W., G. W. Wood, J. B. Bashiruddin, and D. J. Alexander. Nucleic acid sequencing in the diagnosis of avian influenza. Proc. 3rd Int. Symp. Avian Influenza, Madison, Wisconsin, pp. 281-292. 1992.
19. Nestorowicz, A., Y. Kawaoka, W. J. Bean, and R. G. Webster. Molecular analysis of the hemagglutinin genes of Australian H7N7 influenza viruses: role of passerine birds in maintenance or transmission? Virology 160:411-418. 1987.
20. Pearson, J. E., and D. A. Senne. Diagnostic procedures for avian influenza. Proc. 2nd Int. Symp. Avian Influenza, Athens, Georgia, pp. 222-227. 1986.
21. Pearson, J. E., D. A. Senne, and B. Panigrahy. Diagnostic procedures and policies for avian influenza at the national level. Proc. 3rd Int. Symp. Avian Influenza, Madison, Wisconsin, pp. 258-268. 1992.
22. Rohm, C., T. Horimoto, Y. Kawaoka, J. Suss, and R. G. Webster. Do hemagglutinin genes of highly pathogenic avian influenza viruses constitute unique phylogenetic lineages? Virology 209:664670. 1995.
23. Stieneke-Grober, A., M. Vey, H. Angliker, E. Shaw, G. Thomas, C. Roberts, H.-D. Klenk, and W. Garten. Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisinlike endoprotease. EMBO J. 11(7):2407-2414. 1992.
24. Süss, J., J. Schäfer, H. Sinnecker, and R. G. Webster. Influenza virus subtypes in aquatic birds of eastern Germany. Arch. Virol. 135:101-114. 1994.
25. Van Deusen, R. A., V. S. Hinshaw, D. A. Senne, and D. Pellacani. Micro neuraminidase inhibition assay for classification of influenza A virus neuraminidases. Avian Dis. 27:745-750. 1983.
26. Vey, M., M. Orlich, S. Adler, H.-D. Klenk, R. Rott, and W. Garten. Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R. Virology 188:408-413. 1992.
27. Walker, J. A., T. Sakaguchi, Y.- Matsuda, T. Yoshida, and Y. Kawaoka. Location and character of the cellular enzyme that cleaves the hemagglutinin of a virulent avian influenza virus. Virology 190(1): 278-287. 1992.
28. Webster, R. G., Y. Kawaoka, and W. J. Bean, Jr. Molecular changes in A/Chicken/Pennsylvania/83 (H5N2) influenza virus associated with acquisition of virulence. Virology 149:165-173. 1986.
29. Wood, G. W, J. W. McCauley, J. B. Bashiruddin, and D. J. Alexander. Deduced amino acid sequences at the haemagglutinin cleavage site of avian influenza A viruses of H5 and H7 subtypes. Arch. Virol. 130:209-217. 1993.
30. World Health Organization. A revision of the system of nomenclature for influenza viruses: a W.H.O. memorandum. Bull. W.H.O. 58(4):585-591. 1980.