An excess of catalytically required motions inhibits the scavenger decapping enzyme

Nature Chemical Biology

Volumn 11, Issue 9, 2015, Pages 697-704

  Neu, Ancilla ^a   Neu, Ursula ^b,c   Fuchs, Anna Lisa ^a   Schlager, Benjamin ^a,d   Sprangers, Remco ^a  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^d FluidSolids AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DCS1P ENZYME; FUNGAL ENZYME; UNCLASSIFIED DRUG; DCS1 PROTEIN, S CEREVISIAE; GLYCOSIDASE; MESSENGER RNA; MRNA DECAPPING ENZYMES; PROTEIN BINDING; RECOMBINANT PROTEIN; RIBONUCLEASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME REGULATION; ISOTHERMAL TITRATION CALORIMETRY; MOTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POINT MUTATION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SUBSTRATE CONCENTRATION; X RAY CRYSTALLOGRAPHY; ALLOSTERISM; BIOCATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; FEEDBACK SYSTEM; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN MULTIMERIZATION;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENDORIBONUCLEASES; ESCHERICHIA COLI; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION; KINETICS; MOLECULAR DYNAMICS SIMULATION; N-GLYCOSYL HYDROLASES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84939654296     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1866     Document Type: Article

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