메뉴 건너뛰기




Volumn 35, Issue 18, 2015, Pages 3225-3243

LIN28A modulates splicing and gene expression programs in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; LIN28A PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; ENAH PROTEIN, HUMAN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN GROUP A B; HNRNP A1; ISOPROTEIN; LIN28B PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84939639034     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00426-15     Document Type: Article
Times cited : (36)

References (62)
  • 1
    • 84875933577 scopus 로고    scopus 로고
    • Lin28: primal regulator of growth and metabolism in stem cells
    • Shyh-Chang N, Daley GQ. 2013. Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell 12:395-406. http://dx.doi.org/10.1016/j.stem.2013.03.005.
    • (2013) Cell Stem Cell , vol.12 , pp. 395-406
    • Shyh-Chang, N.1    Daley, G.Q.2
  • 2
    • 84865589321 scopus 로고    scopus 로고
    • How does Lin28 let-7 control development and disease?
    • Thornton JE, Gregory RI. 2012. How does Lin28 let-7 control development and disease? Trends Cell Biol 22:474-482. http://dx.doi.org/10.1016/j.tcb.2012.06.001.
    • (2012) Trends Cell Biol , vol.22 , pp. 474-482
    • Thornton, J.E.1    Gregory, R.I.2
  • 3
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans
    • Ambros V, Horvitz HR. 1984. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 226:409-416. http://dx.doi.org/10.1126/science.6494891.
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 4
    • 0037783427 scopus 로고    scopus 로고
    • Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites
    • Moss EG, Tang L. 2003. Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites. Dev Biol 258:432-442. http://dx.doi.org/10.1016/S0012-1606(03)00126-X.
    • (2003) Dev Biol , vol.258 , pp. 432-442
    • Moss, E.G.1    Tang, L.2
  • 5
    • 79953015943 scopus 로고    scopus 로고
    • Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells
    • Peng S, Chen LL, Lei XX, Yang L, Lin H, Carmichael GG, Huang Y. 2011. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells 29:496-504. http://dx.doi.org/10.1002/stem.591.
    • (2011) Stem Cells , vol.29 , pp. 496-504
    • Peng, S.1    Chen, L.L.2    Lei, X.X.3    Yang, L.4    Lin, H.5    Carmichael, G.G.6    Huang, Y.7
  • 6
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE
    • Richards M, Tan SP, Tan JH, Chan WK, Bongso A. 2004. The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells 22:51-64. http://dx.doi.org/10.1634/stemcells.22-1-51.
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3    Chan, W.K.4    Bongso, A.5
  • 7
    • 67650931988 scopus 로고    scopus 로고
    • Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II
    • Lu L, Katsaros D, Shaverdashvili K, Qian B, Wu Y, de la Longrais IA, Preti M, Menato G, Yu H. 2009. Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II. Eur J Cancer 45:2212-2218. http://dx.doi.org/10.1016/j.ejca.2009.05.003.
    • (2009) Eur J Cancer , vol.45 , pp. 2212-2218
    • Lu, L.1    Katsaros, D.2    Shaverdashvili, K.3    Qian, B.4    Wu, Y.5    de la Longrais, I.A.6    Preti, M.7    Menato, G.8    Yu, H.9
  • 9
    • 0344013522 scopus 로고    scopus 로고
    • Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
    • Yang DH, Moss EG. 2003. Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene Expr Patterns 3:719-726. http://dx.doi.org/10.1016/S1567-133X(03)00140-6.
    • (2003) Gene Expr Patterns , vol.3 , pp. 719-726
    • Yang, D.H.1    Moss, E.G.2
  • 11
    • 60549104367 scopus 로고    scopus 로고
    • Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
    • Dangi-Garimella S, Yun J, Eves EM, Newman M, Erkeland SJ, Hammond SM, Minn AJ, Rosner MR. 2009. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 28:347-358. http://dx.doi.org/10.1038/emboj.2008.294.
    • (2009) EMBO J , vol.28 , pp. 347-358
    • Dangi-Garimella, S.1    Yun, J.2    Eves, E.M.3    Newman, M.4    Erkeland, S.J.5    Hammond, S.M.6    Minn, A.J.7    Rosner, M.R.8
  • 12
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman MA, Thomson JM, Hammond SM. 2008. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 14:1539-1549. http://dx.doi.org/10.1261/rna.1155108.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 13
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A, Fuchs H, Smirnova L, Brandt C, Pohl EE, Nitsch R, Wulczyn FG. 2008. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 10:987-993. http://dx.doi.org/10.1038/ncb1759.
    • (2008) Nat Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 14
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI. 2008. Selective blockade of microRNA processing by Lin28. Science 320:97-100. http://dx.doi.org/10.1126/science.1154040.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 16
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C, Hemann MT, Bartel DP. 2007. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315:1576-1579. http://dx.doi.org/10.1126/science.1137999.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 18
    • 84904745887 scopus 로고    scopus 로고
    • Low expression of let-7 predicts poor prognosis in patients with multiple cancers: a meta-analysis
    • Xia Y, Zhu Y, Zhou X, Chen Y. 2014. Low expression of let-7 predicts poor prognosis in patients with multiple cancers: a meta-analysis. Tumour Biol 35:5143-5148. http://dx.doi.org/10.1007/s13277-014-1663-0.
    • (2014) Tumour Biol , vol.35 , pp. 5143-5148
    • Xia, Y.1    Zhu, Y.2    Zhou, X.3    Chen, Y.4
  • 19
    • 77950357078 scopus 로고    scopus 로고
    • LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro
    • Balzer E, Heine C, Jiang Q, Lee VM, Moss EG. 2010. LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro. Development 137:891-900. http://dx.doi.org/10.1242/dev.042895.
    • (2010) Development , vol.137 , pp. 891-900
    • Balzer, E.1    Heine, C.2    Jiang, Q.3    Lee, V.M.4    Moss, E.G.5
  • 20
    • 84869086143 scopus 로고    scopus 로고
    • LIN28A is a suppressor of ER-associated translation in embryonic stem cells
    • Cho J, Chang H, Kwon SC, Kim B, Kim Y, Choe J, Ha M, Kim YK, Kim VN. 2012. LIN28A is a suppressor of ER-associated translation in embryonic stem cells. Cell 151:765-777. http://dx.doi.org/10.1016/j.cell.2012.10.019.
    • (2012) Cell , vol.151 , pp. 765-777
    • Cho, J.1    Chang, H.2    Kwon, S.C.3    Kim, B.4    Kim, Y.5    Choe, J.6    Ha, M.7    Kim, Y.K.8    Kim, V.N.9
  • 21
    • 34247589770 scopus 로고    scopus 로고
    • Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
    • Polesskaya A, Cuvellier S, Naguibneva I, Duquet A, Moss EG, Harel-Bellan A. 2007. Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency. Genes Dev 21:1125-1138. http://dx.doi.org/10.1101/gad.415007.
    • (2007) Genes Dev , vol.21 , pp. 1125-1138
    • Polesskaya, A.1    Cuvellier, S.2    Naguibneva, I.3    Duquet, A.4    Moss, E.G.5    Harel-Bellan, A.6
  • 22
    • 60849116964 scopus 로고    scopus 로고
    • Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells
    • Xu B, Zhang K, Huang Y. 2009. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA 15:357-361. http://dx.doi.org/10.1261/rna.1368009.
    • (2009) RNA , vol.15 , pp. 357-361
    • Xu, B.1    Zhang, K.2    Huang, Y.3
  • 24
    • 84875966667 scopus 로고    scopus 로고
    • Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition
    • Hafner M, Max KE, Bandaru P, Morozov P, Gerstberger S, Brown M, Molina H, Tuschl T. 2013. Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition. RNA 19:613-626. http://dx.doi.org/10.1261/rna.036491.112.
    • (2013) RNA , vol.19 , pp. 613-626
    • Hafner, M.1    Max, K.E.2    Bandaru, P.3    Morozov, P.4    Gerstberger, S.5    Brown, M.6    Molina, H.7    Tuschl, T.8
  • 25
    • 84861206686 scopus 로고    scopus 로고
    • Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer
    • Li N, Zhong X, Lin X, Guo J, Zou L, Tanyi JL, Shao Z, Liang S, Wang LP, Hwang WT, Katsaros D, Montone K, Zhao X, Zhang L. 2012. Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer. J Biol Chem 287:17386-17397. http://dx.doi.org/10.1074/jbc.M111.321158.
    • (2012) J Biol Chem , vol.287 , pp. 17386-17397
    • Li, N.1    Zhong, X.2    Lin, X.3    Guo, J.4    Zou, L.5    Tanyi, J.L.6    Shao, Z.7    Liang, S.8    Wang, L.P.9    Hwang, W.T.10    Katsaros, D.11    Montone, K.12    Zhao, X.13    Zhang, L.14
  • 27
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. 1956. On the origin of cancer cells. Science 123:309-314. http://dx.doi.org/10.1126/science.123.3191.309.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 29
    • 84863613073 scopus 로고    scopus 로고
    • Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells
    • Lv K, Liu L, Wang L, Yu J, Liu X, Cheng Y, Dong M, Teng R, Wu L, Fu P, Deng W, Hu W, Teng L. 2012. Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells. PLoS One 7:e40008. http://dx.doi.org/10.1371/journal.pone.0040008.
    • (2012) PLoS One , vol.7 , pp. e40008
    • Lv, K.1    Liu, L.2    Wang, L.3    Yu, J.4    Liu, X.5    Cheng, Y.6    Dong, M.7    Teng, R.8    Wu, L.9    Fu, P.10    Deng, W.11    Hu, W.12    Teng, L.13
  • 30
    • 33845275018 scopus 로고    scopus 로고
    • RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene JD, Komisarow JM, Friedersdorf MB. 2006. RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat Protoc 1:302-307. http://dx.doi.org/10.1038/nprot.2006.47.
    • (2006) Nat Protoc , vol.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.B.3
  • 31
    • 33750987942 scopus 로고    scopus 로고
    • The antigenic determinants on HIV p24 for CD4 T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry
    • Williams JG, Tomer KB, Hioe CE, Zolla-Pazner S, Norris PJ. 2006. The antigenic determinants on HIV p24 for CD4 T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry. J Am Soc Mass Spectrom 17:1560-1569. http://dx.doi.org/10.1016/j.jasms.2006.06.011.
    • (2006) J Am Soc Mass Spectrom , vol.17 , pp. 1560-1569
    • Williams, J.G.1    Tomer, K.B.2    Hioe, C.E.3    Zolla-Pazner, S.4    Norris, P.J.5
  • 32
    • 0041630956 scopus 로고    scopus 로고
    • Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression
    • Kinyamu HK, Archer TK. 2003. Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression. Mol Cell Biol 23:5867-5881. http://dx.doi.org/10.1128/MCB.23.16.5867-5881.2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 5867-5881
    • Kinyamu, H.K.1    Archer, T.K.2
  • 33
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10:R25. http://dx.doi.org/10.1186/gb-2009-10-3-r25.
    • (2009) Genome Biol , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 34
    • 0032492846 scopus 로고    scopus 로고
    • Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
    • Fryer CJ, Archer TK. 1998. Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex. Nature 393:88-91. http://dx.doi.org/10.1038/30032.
    • (1998) Nature , vol.393 , pp. 88-91
    • Fryer, C.J.1    Archer, T.K.2
  • 35
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network. 2012. Comprehensive molecular portraits of human breast tumours. Nature 490:61-70. http://dx.doi.org/10.1038/nature11412.
    • (2012) Nature , vol.490 , pp. 61-70
  • 36
    • 55949117369 scopus 로고    scopus 로고
    • Genome wide transcriptional profiling in breast cancer cells reveals distinct changes in hormone receptor target genes and chromatin modifying enzymes after proteasome inhibition
    • Kinyamu HK, Collins JB, Grissom SF, Hebbar PB, Archer TK. 2008. Genome wide transcriptional profiling in breast cancer cells reveals distinct changes in hormone receptor target genes and chromatin modifying enzymes after proteasome inhibition. Mol Carcinog 47:845-885. http://dx.doi.org/10.1002/mc.20440.
    • (2008) Mol Carcinog , vol.47 , pp. 845-885
    • Kinyamu, H.K.1    Collins, J.B.2    Grissom, S.F.3    Hebbar, P.B.4    Archer, T.K.5
  • 37
    • 62549132535 scopus 로고    scopus 로고
    • Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells
    • Darr H, Benvenisty N. 2009. Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells. Stem Cells 27:352-362. http://dx.doi.org/10.1634/stemcells.2008-0720.
    • (2009) Stem Cells , vol.27 , pp. 352-362
    • Darr, H.1    Benvenisty, N.2
  • 39
    • 84884181118 scopus 로고    scopus 로고
    • hnRNP A1: the Swiss army knife of gene expression
    • Jean-Philippe J, Paz S, Caputi M. 2013. hnRNP A1: the Swiss army knife of gene expression. Int J Mol Sci 14:18999-19024. http://dx.doi.org/10.3390/ijms140918999.
    • (2013) Int J Mol Sci , vol.14 , pp. 18999-19024
    • Jean-Philippe, J.1    Paz, S.2    Caputi, M.3
  • 40
    • 84862777397 scopus 로고    scopus 로고
    • Concentration-dependent control of pyruvate kinaseMmutually exclusive splicing by hnRNP proteins
    • Chen M, David CJ, Manley JL. 2012. Concentration-dependent control of pyruvate kinaseMmutually exclusive splicing by hnRNP proteins. Nat Struct Mol Biol 19:346-354. http://dx.doi.org/10.1038/nsmb.2219.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 346-354
    • Chen, M.1    David, C.J.2    Manley, J.L.3
  • 41
    • 76649102764 scopus 로고    scopus 로고
    • The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
    • Clower CV, Chatterjee D, Wang Z, Cantley LC, Vander Heiden MG, Krainer AR. 2010. The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proc Natl Acad Sci U S A 107:1894-1899. http://dx.doi.org/10.1073/pnas.0914845107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1894-1899
    • Clower, C.V.1    Chatterjee, D.2    Wang, Z.3    Cantley, L.C.4    Vander Heiden, M.G.5    Krainer, A.R.6
  • 42
    • 75149150660 scopus 로고    scopus 로고
    • hnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • David CJ, Chen M, Assanah M, Canoll P, Manley JL. 2010. hnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 463:364-368. http://dx.doi.org/10.1038/nature08697.
    • (2010) Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3    Canoll, P.4    Manley, J.L.5
  • 44
    • 33645048173 scopus 로고    scopus 로고
    • The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor- negative tumors
    • Di Modugno F, Mottolese M, Di Benedetto A, Conidi A, Novelli F, Perracchio L, Venturo I, Botti C, Jager E, Santoni A, Natali PG, Nistico P. 2006. The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor- negative tumors. Clin Cancer Res 12:1470-1478. http://dx.doi.org/10.1158/1078-0432.CCR-05-2027.
    • (2006) Clin Cancer Res , vol.12 , pp. 1470-1478
    • Di Modugno, F.1    Mottolese, M.2    Di Benedetto, A.3    Conidi, A.4    Novelli, F.5    Perracchio, L.6    Venturo, I.7    Botti, C.8    Jager, E.9    Santoni, A.10    Natali, P.G.11    Nistico, P.12
  • 45
    • 84868609464 scopus 로고    scopus 로고
    • Clinical significance of Mena and Her-2 expression in breast cancer
    • Du JW, Xu KY, Fang LY, Qi XL. 2012. Clinical significance of Mena and Her-2 expression in breast cancer. Eur J Gynaecol Oncol 33:455-458.
    • (2012) Eur J Gynaecol Oncol , vol.33 , pp. 455-458
    • Du, J.W.1    Xu, K.Y.2    Fang, L.Y.3    Qi, X.L.4
  • 47
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate
    • Ward PS, Thompson CB. 2012. Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate. Cancer Cell 21:297-308. http://dx.doi.org/10.1016/j.ccr.2012.02.014.
    • (2012) Cancer Cell , vol.21 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 49
    • 1942469956 scopus 로고    scopus 로고
    • MGMT: its role in cancer aetiology and cancer therapeutics
    • Gerson SL. 2004. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer 4:296-307. http://dx.doi.org/10.1038/nrc1319.
    • (2004) Nat Rev Cancer , vol.4 , pp. 296-307
    • Gerson, S.L.1
  • 51
    • 73649132649 scopus 로고    scopus 로고
    • Quantitative organelle proteomics of MCF-7 breast cancer cells reveals multiple subcellular locations for proteins in cellular functional processes
    • Qattan AT, Mulvey C, Crawford M, Natale DA, Godovac-Zimmermann J. 2010. Quantitative organelle proteomics of MCF-7 breast cancer cells reveals multiple subcellular locations for proteins in cellular functional processes. J Proteome Res 9:495-508. http://dx.doi.org/10.1021/pr9008332.
    • (2010) J Proteome Res , vol.9 , pp. 495-508
    • Qattan, A.T.1    Mulvey, C.2    Crawford, M.3    Natale, D.A.4    Godovac-Zimmermann, J.5
  • 52
    • 0028077730 scopus 로고
    • Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors
    • Caceres JF, Stamm S, Helfman DM, Krainer AR. 1994. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265:1706-1709. http://dx.doi.org/10.1126/science.8085156.
    • (1994) Science , vol.265 , pp. 1706-1709
    • Caceres, J.F.1    Stamm, S.2    Helfman, D.M.3    Krainer, A.R.4
  • 53
    • 0026543785 scopus 로고
    • Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2
    • Mayeda A, Krainer AR. 1992. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell 68:365-375. http://dx.doi.org/10.1016/0092-8674(92)90477-T.
    • (1992) Cell , vol.68 , pp. 365-375
    • Mayeda, A.1    Krainer, A.R.2
  • 55
    • 34047257715 scopus 로고    scopus 로고
    • Molecular cloning of hMena (ENAH) and its splice variant hMena 11a:epidermal growth factor increases their expression and stimulates hMena 11a phosphorylation in breast cancer cell lines
    • Di Modugno F, DeMonte L, Balsamo M, Bronzi G, Nicotra MR, Alessio M, Jager E, Condeelis JS, Santoni A, Natali PG, Nistico P. 2007. Molecular cloning of hMena (ENAH) and its splice variant hMena 11a:epidermal growth factor increases their expression and stimulates hMena 11a phosphorylation in breast cancer cell lines. Cancer Res 67:2657-2665. http://dx.doi.org/10.1158/0008-5472.CAN-06-1997.
    • (2007) Cancer Res , vol.67 , pp. 2657-2665
    • Di Modugno, F.1    DeMonte, L.2    Balsamo, M.3    Bronzi, G.4    Nicotra, M.R.5    Alessio, M.6    Jager, E.7    Condeelis, J.S.8    Santoni, A.9    Natali, P.G.10    Nistico, P.11
  • 57
  • 58
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation
    • Iliopoulos D, Hirsch HA, Struhl K. 2009. An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 139:693-706. http://dx.doi.org/10.1016/j.cell.2009.10.014.
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 59
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged
    • David CJ, Manley JL. 2010. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 24:2343-2364. http://dx.doi.org/10.1101/gad.1973010.
    • (2010) Genes Dev , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 62
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. 2011. Hallmarks of cancer: the next generation. Cell 144:646-674. http://dx.doi.org/10.1016/j.cell.2011.02.013.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.