메뉴 건너뛰기




Volumn 53, Issue 8, 2015, Pages 797-806

Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak

Author keywords

Antidote administration; Clinical effectiveness; Hospital treatment; Sequelae of poisoning; Treatment outcome

Indexed keywords

4 METHYLPYRAZOLE; ALCOHOL; BICARBONATE; CREATININE; FOLIC ACID; HEPARIN; METHANOL; ANTIDOTE; PYRAZOLE DERIVATIVE;

EID: 84939599573     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2015.1059946     Document Type: Article
Times cited : (65)

References (36)
  • 1
    • 33847101899 scopus 로고    scopus 로고
    • Methanol mass poisoning in Estonia: Outbreak in 154 patients
    • Paasma R, Hovda KE, Tikkerberi A, Jacobsen D. Methanol mass poisoning in Estonia: outbreak in 154 patients. Clin Toxicol 2007; 45: 152-157.
    • (2007) Clin Toxicol , vol.45 , pp. 152-157
    • Paasma, R.1    Hovda, K.E.2    Tikkerberi, A.3    Jacobsen, D.4
  • 2
    • 22644441639 scopus 로고    scopus 로고
    • Methanol outbreak in Norway 2002-2004: Epidemiology, clinical features and prognostic signs
    • Hovda KE, Hunderi OH, Tafjord AB, Dunlop O, Rudberg N, Jacobsen D. Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs. J Intern Med 2005; 258: 181-190.
    • (2005) J Intern Med , vol.258 , pp. 181-190
    • Hovda, K.E.1    Hunderi, O.H.2    Tafjord, A.B.3    Dunlop, O.4    Rudberg, N.5    Jacobsen, D.6
  • 3
    • 84916227323 scopus 로고    scopus 로고
    • Czech mass methanol outbreak 2012: Epidemiology, challenges and clinical features
    • Zakharov S, Pelclova D, Urban P, Navratil T, Diblik P, Kuthan P, et al. Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features. Clin Toxicol 2014; 52: 1013-1024.
    • (2014) Clin Toxicol , vol.52 , pp. 1013-1024
    • Zakharov, S.1    Pelclova, D.2    Urban, P.3    Navratil, T.4    Diblik, P.5    Kuthan, P.6
  • 6
    • 0010252197 scopus 로고    scopus 로고
    • Methanol-laced moonshine kills 140 in Kenya
    • Ahmad K. Methanol-laced moonshine kills 140 in Kenya. The Lancet 2000; 356: 1911.
    • (2000) The Lancet , vol.356 , pp. 1911
    • Ahmad, K.1
  • 7
    • 0036368787 scopus 로고    scopus 로고
    • American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning
    • Barceloux DG, Bond GR, Krenzelok EP, Cooper H, Vale JA. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol-Clin Toxicol 2002; 40: 415-446.
    • (2002) J Toxicol-Clin Toxicol , vol.40 , pp. 415-446
    • Barceloux, D.G.1    Bond, G.R.2    Krenzelok, E.P.3    Cooper, H.4    Vale, J.A.5
  • 8
    • 14944341595 scopus 로고    scopus 로고
    • Current recommendations for treatment of severe toxic alcohol poisonings
    • Megarbane B, Borron SW, Baud FJ. Current recommendations for treatment of severe toxic alcohol poisonings. Intensive Care Med 2005; 31: 189-195.
    • (2005) Intensive Care Med , vol.31 , pp. 189-195
    • Megarbane, B.1    Borron, S.W.2    Baud, F.J.3
  • 9
    • 0025863482 scopus 로고
    • Methanol and formic-acid toxicity-biochemical mechanisms
    • Liesivuori J, Savolainen H. Methanol and formic-acid toxicity-biochemical mechanisms. Pharmacol Toxicol 1991; 69: 157-163.
    • (1991) Pharmacol Toxicol , vol.69 , pp. 157-163
    • Liesivuori, J.1    Savolainen, H.2
  • 10
    • 0020674852 scopus 로고
    • Formate concentrations in plasma from patients poisoned with methanol
    • Sejersted OM, Jacobsen D, Ovrebo S, Jansen H. Formate concentrations in plasma from patients poisoned with methanol. Acta Med Scand 1983; 213: 105-110.
    • (1983) Acta Med Scand , vol.213 , pp. 105-110
    • Sejersted, O.M.1    Jacobsen, D.2    Ovrebo, S.3    Jansen, H.4
  • 13
    • 84926360250 scopus 로고    scopus 로고
    • The measurement of serum formate concentration useful in the diagnostics of acute methanol poisoning? A prospective study of 38 patients
    • Zakharov S, Kurcova I, Navratil T, Salek T, Pelclova D. Is the measurement of serum formate concentration useful in the diagnostics of acute methanol poisoning? A prospective study of 38 patients. Basic Clin Pharmacol Toxicol 2015; 116: 445-451. doi: 10.1111/bcpt.12338.
    • (2015) Basic Clin Pharmacol Toxicol , vol.116 , pp. 445-451
    • Zakharov, S.1    Kurcova, I.2    Navratil, T.3    Salek, T.4    Pelclova, D.5
  • 16
    • 84867733969 scopus 로고    scopus 로고
    • Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes-A multicenter study
    • Paasma R, Hovda KE, Hassanian-Moghaddam H, Brahmi N, Afshari R, Sandvik L, Jacobsen D. Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes-a multicenter study. Clin Toxicol 2012; 50: 823-831.
    • (2012) Clin Toxicol , vol.50 , pp. 823-831
    • Paasma, R.1    Hovda, K.E.2    Hassanian-Moghaddam, H.3    Brahmi, N.4    Afshari, R.5    Sandvik, L.6    Jacobsen, D.7
  • 17
    • 27744586268 scopus 로고    scopus 로고
    • Increased serum formate in the diagnosis of methanol poisoning
    • Hovda KE, Urdal P, Jacobsen D. Increased serum formate in the diagnosis of methanol poisoning. J Anal Toxicol 2005; 29: 586-588.
    • (2005) J Anal Toxicol , vol.29 , pp. 586-588
    • Hovda, K.E.1    Urdal, P.2    Jacobsen, D.3
  • 18
    • 79961168784 scopus 로고    scopus 로고
    • Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning
    • Sanaei-Zadeh H, Esfeh SK, Zamani N, Jamshidi F, Shadnia S. Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning. J Med Toxicol 2011; 7: 189-194.
    • (2011) J Med Toxicol , vol.7 , pp. 189-194
    • Sanaei-Zadeh, H.1    Esfeh, S.K.2    Zamani, N.3    Jamshidi, F.4    Shadnia, S.5
  • 19
    • 0020400582 scopus 로고
    • Prevention of methanol toxicity by ethanol therapy
    • Bergeron R, Cardinal J, Geadah D. Prevention of methanol toxicity by ethanol therapy. N Engl J Med 1982; 307: 1528.
    • (1982) N Engl J Med , vol.307 , pp. 1528
    • Bergeron, R.1    Cardinal, J.2    Geadah, D.3
  • 20
    • 0036715820 scopus 로고    scopus 로고
    • Ethanol therapy for methanol poisoning: Duration and problems
    • Hantson P, Wittebole X, Haufroid V. Ethanol therapy for methanol poisoning: duration and problems. Eur J Emerg Med 2002; 9: 278-279.
    • (2002) Eur J Emerg Med , vol.9 , pp. 278-279
    • Hantson, P.1    Wittebole, X.2    Haufroid, V.3
  • 25
    • 84916203001 scopus 로고    scopus 로고
    • Fomepizole in the treatment of acute methanol poisonings: Experience from the Czech mass methanol outbreak 2012-2013
    • Zakharov S, Navratil T, Pelclova D. Fomepizole in the treatment of acute methanol poisonings: experience from the Czech mass methanol outbreak 2012-2013. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014; 158: 641-649.
    • (2014) Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub , vol.158 , pp. 641-649
    • Zakharov, S.1    Navratil, T.2    Pelclova, D.3
  • 26
    • 33749252978 scopus 로고    scopus 로고
    • WHO 2014. Available from (Last accessed on February 20 2014)
    • WHO. 18th Model List of Essential Medicines 2013; 2014. Available from: http://www.who.int/medicines/publications/essentialmedicines/18th-EML-Final-web-8Jul13.pdf?ua = 1. (Last accessed on February 20, 2014)
    • (2013) 18th Model List of Essential Medicines
  • 27
    • 66149113684 scopus 로고    scopus 로고
    • Fomepizole for ethylene glycol and methanol poisoning
    • Brent J. Fomepizole for ethylene glycol and methanol poisoning. N Engl J Med 2009; 360: 2216-2223.
    • (2009) N Engl J Med , vol.360 , pp. 2216-2223
    • Brent, J.1
  • 28
    • 77954221448 scopus 로고    scopus 로고
    • Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings
    • Brent J. Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. Clin Toxicol 2010; 48: 401-406.
    • (2010) Clin Toxicol , vol.48 , pp. 401-406
    • Brent, J.1
  • 29
    • 56049120321 scopus 로고    scopus 로고
    • Expert opinion: Fomepizole may ameliorate the need for hemodialysis in methanol poisoning
    • Hovda KE, Jacobsen D. Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. Hum Exp Toxicol 2008; 27: 539-546.
    • (2008) Hum Exp Toxicol , vol.27 , pp. 539-546
    • Hovda, K.E.1    Jacobsen, D.2
  • 31
    • 84886744604 scopus 로고    scopus 로고
    • A systematic review of ethanol and fomepizole use in toxic alcohol ingestions
    • Beatty L, Green R, Magee K, Zed P. A systematic review of ethanol and fomepizole use in toxic alcohol ingestions. Emergen Med Int 2013; 2013: 14.
    • (2013) Emergen Med Int , vol.2013 , pp. 14
    • Beatty, L.1    Green, R.2    Magee, K.3    Zed, P.4
  • 33
    • 64949131311 scopus 로고    scopus 로고
    • Methanol poisoning and long term sequelae-A six years follow-up after a large methanol outbreak
    • Paasma R, Hovda KE, Jacobsen D. Methanol poisoning and long term sequelae-a six years follow-up after a large methanol outbreak. BMC Clin Pharmacol 2009; 9: 5.
    • (2009) BMC Clin Pharmacol , vol.9 , pp. 5
    • Paasma, R.1    Hovda, K.E.2    Jacobsen, D.3
  • 34
    • 62349105974 scopus 로고    scopus 로고
    • Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: A comparison of ethanol and fomepizole
    • Lepik KJ, Levy AR, Sobolev BG, Purssell RA, DeWitt CR, Erhardt GD, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med 2009; 53: 439-450.
    • (2009) Ann Emerg Med , vol.53 , pp. 439-450
    • Lepik, K.J.1    Levy, A.R.2    Sobolev, B.G.3    Purssell, R.A.4    DeWitt, C.R.5    Erhardt, G.D.6
  • 36
    • 0034518916 scopus 로고    scopus 로고
    • Nystagmus secondary to fomepizole administration in a pediatric patient
    • Benitez JG, Swanson-Bierman B, Krenzelok EP. Nystagmus secondary to fomepizole administration in a pediatric patient. Clin Toxicol 2000; 38: 795-798.
    • (2000) Clin Toxicol , vol.38 , pp. 795-798
    • Benitez, J.G.1    Swanson-Bierman, B.2    Krenzelok, E.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.