Allele-specific transcriptional regulation of IRF4 in melanocytes is mediated by chromatin looping of the intronic rs12203592 enhancer to the IRF4 promoter

Human Molecular Genetics

Volumn 24, Issue 9, 2015, Pages 2649-2661

  Visser, Mijke ^a   Palstra, Robert Jan ^a   Kayser, Manfred ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; INTERFERON REGULATORY FACTOR 4; MESSENGER RNA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YY1; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; TRANSACTIVATOR PROTEIN;

ALLELE; ARTICLE; CHROMATIN STRUCTURE; CONFORMATIONAL TRANSITION; EMBRYO; ENHANCER REGION; EPIDERMIS; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENOTYPE; HISTONE ACETYLATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; MELANOCYTE; NEWBORN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RESTRICTION FRAGMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN COLOR; SKIN PIGMENTATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HIGH THROUGHPUT SEQUENCING; METABOLISM;

ALLELES; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; ENHANCER ELEMENTS, GENETIC; EPIDERMIS; GENE EXPRESSION REGULATION; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INTERFERON REGULATORY FACTORS; INTRONS; MELANOCYTES; MODELS, BIOLOGICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 84939573323     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv029     Document Type: Article

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