메뉴 건너뛰기




Volumn 166, Issue 2, 2011, Pages 269-280

Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2rγ null H2-Ab1 tm1Gru Tg (human leucocyte antigen D-related 4) mice: A mouse model of human allogeneic graft-versus-host disease

Author keywords

Graft versus host disease; IL 2R 'common' gamma chain; SCID; T cell

Indexed keywords

HLA DR4 ANTIGEN; INTERLEUKIN 2 RECEPTOR GAMMA;

EID: 80053654946     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2011.04462.x     Document Type: Article
Times cited : (81)

References (57)
  • 1
    • 76749123838 scopus 로고    scopus 로고
    • Transplantation immunology: solid organ and bone marrow
    • Chinen J, Buckley RH. Transplantation immunology: solid organ and bone marrow. J Allergy Clin Immunol 2010; 125:S324-35.
    • (2010) J Allergy Clin Immunol , vol.125
    • Chinen, J.1    Buckley, R.H.2
  • 2
    • 77649181500 scopus 로고    scopus 로고
    • Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer
    • Jenq RR, van den Brink MRM. Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer. Nat Rev Cancer 2010; 10:213-21.
    • (2010) Nat Rev Cancer , vol.10 , pp. 213-221
    • Jenq, R.R.1    van den Brink, M.R.M.2
  • 5
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik WD. Graft-versus-host disease. Nat Rev Immunol 2007; 7:340-52.
    • (2007) Nat Rev Immunol , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 6
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic hematopoietic stem cell transplantation
    • Welniak LA, Blazar BR, Murphy WJ. Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol 2007; 25:139-70.
    • (2007) Annu Rev Immunol , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 7
    • 40049109392 scopus 로고    scopus 로고
    • Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • Duran-Struuck R, Reddy P. Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Transplantation 2008; 85:303-8.
    • (2008) Transplantation , vol.85 , pp. 303-308
    • Duran-Struuck, R.1    Reddy, P.2
  • 8
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho VT, Soiffer RJ. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood 2001; 98:3192-204.
    • (2001) Blood , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 9
    • 30344461633 scopus 로고    scopus 로고
    • Pathophysiology of graft-versus-host disease
    • Ferrara JL, Reddy P. Pathophysiology of graft-versus-host disease. Semin Hematol 2006; 43:3-10.
    • (2006) Semin Hematol , vol.43 , pp. 3-10
    • Ferrara, J.L.1    Reddy, P.2
  • 10
    • 77950471448 scopus 로고    scopus 로고
    • Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors
    • Penack O, Holler E, van den Brink MR. Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors. Blood 2010; 115:1865-72.
    • (2010) Blood , vol.115 , pp. 1865-1872
    • Penack, O.1    Holler, E.2    van den Brink, M.R.3
  • 11
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines
    • Hill GR, Crawford JM, Cooke KR, Brinson YS, Pan L, Ferrara JL. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997; 90:3204-13.
    • (1997) Blood , vol.90 , pp. 3204-3213
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3    Brinson, Y.S.4    Pan, L.5    Ferrara, J.L.6
  • 12
    • 0032717103 scopus 로고    scopus 로고
    • Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia
    • Hill GR, Teshima T, Gerbitz A etal. Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia. J Clin Invest 1999; 104:459-67.
    • (1999) J Clin Invest , vol.104 , pp. 459-467
    • Hill, G.R.1    Teshima, T.2    Gerbitz, A.3
  • 13
    • 0034978248 scopus 로고    scopus 로고
    • LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation
    • Cooke KR, Gerbitz A, Crawford JM etal. LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation. J Clin Invest 2001; 107:1581-9.
    • (2001) J Clin Invest , vol.107 , pp. 1581-1589
    • Cooke, K.R.1    Gerbitz, A.2    Crawford, J.M.3
  • 14
    • 52249118732 scopus 로고    scopus 로고
    • Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease
    • Li M, Sun K, Welniak LA, Murphy WJ. Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease. Exp Opin Pharmacother 2008; 9:2305-16.
    • (2008) Exp Opin Pharmacother , vol.9 , pp. 2305-2316
    • Li, M.1    Sun, K.2    Welniak, L.A.3    Murphy, W.J.4
  • 15
    • 73349118783 scopus 로고    scopus 로고
    • Acute graft-versus-host disease: from the bench to the bedside
    • Socié G, Blazar BR. Acute graft-versus-host disease: from the bench to the bedside. Blood 2009; 114:4327-36.
    • (2009) Blood , vol.114 , pp. 4327-4336
    • Socié, G.1    Blazar, B.R.2
  • 16
    • 33846630040 scopus 로고    scopus 로고
    • Humanized mice in translational biomedical research
    • Shultz LD, Ishikawa F, Greiner DL. Humanized mice in translational biomedical research. Nat Rev Immunol 2007; 7:118-30.
    • (2007) Nat Rev Immunol , vol.7 , pp. 118-130
    • Shultz, L.D.1    Ishikawa, F.2    Greiner, D.L.3
  • 17
    • 0027178774 scopus 로고
    • Human peripheral blood xenografts in the SCID mouse: characterization of immunologic reconstitution
    • Hesselton RM, Koup RA, Cromwell MA, Graham BS, Johns M, Sullivan JL. Human peripheral blood xenografts in the SCID mouse: characterization of immunologic reconstitution. J Infect Dis 1993; 168:630-40.
    • (1993) J Infect Dis , vol.168 , pp. 630-640
    • Hesselton, R.M.1    Koup, R.A.2    Cromwell, M.A.3    Graham, B.S.4    Johns, M.5    Sullivan, J.L.6
  • 18
    • 0027319753 scopus 로고
    • Immunohistology and immunocytology of human T-cell chimerism and graft-versus-host disease in SCID mice
    • Hoffmann-Fezer G, Gall C, Zengerle U, Kranz B, Thierfelder S. Immunohistology and immunocytology of human T-cell chimerism and graft-versus-host disease in SCID mice. Blood 1993; 81:3440-8.
    • (1993) Blood , vol.81 , pp. 3440-3448
    • Hoffmann-Fezer, G.1    Gall, C.2    Zengerle, U.3    Kranz, B.4    Thierfelder, S.5
  • 19
    • 0027514219 scopus 로고
    • The fate of human peripheral blood lymphocytes after transplantation into SCID mice
    • Martino G, Anastasi J, Feng J etal. The fate of human peripheral blood lymphocytes after transplantation into SCID mice. Eur J Immunol 1993; 23:1023-8.
    • (1993) Eur J Immunol , vol.23 , pp. 1023-1028
    • Martino, G.1    Anastasi, J.2    Feng, J.3
  • 20
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier DE, Gulizia RJ, Baird SM, Wilson DB. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988; 335:256-9.
    • (1988) Nature , vol.335 , pp. 256-259
    • Mosier, D.E.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 21
    • 0026554409 scopus 로고
    • Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions
    • Murphy WJ, Bennett M, Anver MR, Baseler M, Longo DL. Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions. Eur J Immunol 1992; 22:1421-7.
    • (1992) Eur J Immunol , vol.22 , pp. 1421-1427
    • Murphy, W.J.1    Bennett, M.2    Anver, M.R.3    Baseler, M.4    Longo, D.L.5
  • 22
    • 0028081364 scopus 로고
    • Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras
    • Tary-Lehmann M, Lehmann PV, Schols D, Roncarolo MG, Saxon A. Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras. J Exp Med 1994; 180:1817-27.
    • (1994) J Exp Med , vol.180 , pp. 1817-1827
    • Tary-Lehmann, M.1    Lehmann, P.V.2    Schols, D.3    Roncarolo, M.G.4    Saxon, A.5
  • 24
    • 0033771643 scopus 로고    scopus 로고
    • Antigen-specific T cell responses in human peripheral blood leucocyte (hu-PBL)-mouse chimera conditioned with radiation and an antibody directed against the mouse IL-2 receptor beta-chain
    • Cao T, Leroux-Roels G. Antigen-specific T cell responses in human peripheral blood leucocyte (hu-PBL)-mouse chimera conditioned with radiation and an antibody directed against the mouse IL-2 receptor beta-chain. Clin Exp Immunol 2000; 122:117-23.
    • (2000) Clin Exp Immunol , vol.122 , pp. 117-123
    • Cao, T.1    Leroux-Roels, G.2
  • 25
    • 53449091065 scopus 로고    scopus 로고
    • Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells
    • Hippen KL, Harker-Murray P, Porter SB etal. Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells. Blood 2008; 112:2847-57.
    • (2008) Blood , vol.112 , pp. 2847-2857
    • Hippen, K.L.1    Harker-Murray, P.2    Porter, S.B.3
  • 26
    • 0027287485 scopus 로고
    • Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency
    • Murphy WJ, Conlon KC, Sayers TJ etal. Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency. J Immunol 1993; 150:3634-42.
    • (1993) J Immunol , vol.150 , pp. 3634-3642
    • Murphy, W.J.1    Conlon, K.C.2    Sayers, T.J.3
  • 27
    • 36148965120 scopus 로고    scopus 로고
    • Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice
    • Nervi B, Rettig MP, Ritchey JK etal. Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice. Exp Hematol 2007; 35:1823-38.
    • (2007) Exp Hematol , vol.35 , pp. 1823-1838
    • Nervi, B.1    Rettig, M.P.2    Ritchey, J.K.3
  • 28
    • 0028343691 scopus 로고
    • Human primary immune response in SCID mice engrafted with human peripheral blood lymphocytes
    • Sandhu J, Shpitz B, Gallinger S, Hozumi N. Human primary immune response in SCID mice engrafted with human peripheral blood lymphocytes. J Immunol 1994; 152:3806-13.
    • (1994) J Immunol , vol.152 , pp. 3806-3813
    • Sandhu, J.1    Shpitz, B.2    Gallinger, S.3    Hozumi, N.4
  • 29
    • 0029144933 scopus 로고
    • A human model of xenogeneic graft-versus-host disease in SCID mice engrafted with human peripheral blood lymphocytes
    • Sandhu JS, Gorczynski R, Shpitz B, Gallinger S, Nguyen HP, Hozumi N. A human model of xenogeneic graft-versus-host disease in SCID mice engrafted with human peripheral blood lymphocytes. Transplantation 1995; 60:179-84.
    • (1995) Transplantation , vol.60 , pp. 179-184
    • Sandhu, J.S.1    Gorczynski, R.2    Shpitz, B.3    Gallinger, S.4    Nguyen, H.P.5    Hozumi, N.6
  • 30
    • 0028205623 scopus 로고
    • High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1
    • Shpitz B, Chambers CA, Singhal AB etal. High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1. J Immunol Methods 1994; 169:1-15.
    • (1994) J Immunol Methods , vol.169 , pp. 1-15
    • Shpitz, B.1    Chambers, C.A.2    Singhal, A.B.3
  • 31
    • 33845788763 scopus 로고    scopus 로고
    • Quantitative assessment of human T lymphocytes in RAG2(-/-)gammac(-/-) mice: the impact of ex vivo manipulation on in vivo functionality
    • van Rijn RS, Simonetti ER, Hagenbeek A etal. Quantitative assessment of human T lymphocytes in RAG2(-/-)gammac(-/-) mice: the impact of ex vivo manipulation on in vivo functionality. Exp Hematol 2007; 35:117-27.
    • (2007) Exp Hematol , vol.35 , pp. 117-127
    • van Rijn, R.S.1    Simonetti, E.R.2    Hagenbeek, A.3
  • 32
    • 0141481990 scopus 로고    scopus 로고
    • A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice
    • van Rijn RS, Simonetti ER, Hagenbeek A etal. A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice. Blood 2003; 102:2522-31.
    • (2003) Blood , vol.102 , pp. 2522-2531
    • van Rijn, R.S.1    Simonetti, E.R.2    Hagenbeek, A.3
  • 33
    • 0031704911 scopus 로고    scopus 로고
    • Murine IL-2 receptor beta chain blockade improves human leukocyte engraftment in SCID mice
    • Tournoy KG, Depraetere S, Meuleman P, Leroux-Roels G, Pauwels RA. Murine IL-2 receptor beta chain blockade improves human leukocyte engraftment in SCID mice. Eur J Immunol 1998; 28:3221-30.
    • (1998) Eur J Immunol , vol.28 , pp. 3221-3230
    • Tournoy, K.G.1    Depraetere, S.2    Meuleman, P.3    Leroux-Roels, G.4    Pauwels, R.A.5
  • 34
    • 0033967781 scopus 로고    scopus 로고
    • Mouse strain and conditioning regimen determine survival and function of human leucocytes in immunodeficient mice
    • Tournoy KG, Depraetere S, Pauwels RA, Leroux-Roels GG. Mouse strain and conditioning regimen determine survival and function of human leucocytes in immunodeficient mice. Clin Exp Immunol 2000; 119:231-9.
    • (2000) Clin Exp Immunol , vol.119 , pp. 231-239
    • Tournoy, K.G.1    Depraetere, S.2    Pauwels, R.A.3    Leroux-Roels, G.G.4
  • 35
    • 20844434966 scopus 로고    scopus 로고
    • Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells
    • Shultz LD, Lyons BL, Burzenski LM etal. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 2005; 174:6477-89.
    • (2005) J Immunol , vol.174 , pp. 6477-6489
    • Shultz, L.D.1    Lyons, B.L.2    Burzenski, L.M.3
  • 36
    • 66849091880 scopus 로고    scopus 로고
    • Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex
    • King MA, Covassin L, Brehm MA etal. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol 2009; 157:104-18.
    • (2009) Clin Exp Immunol , vol.157 , pp. 104-118
    • King, M.A.1    Covassin, L.2    Brehm, M.A.3
  • 37
    • 39149112228 scopus 로고    scopus 로고
    • A new Hu-PBL model for the study of human isloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene
    • King M, Pearson T, Shultz LD etal. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol 2008; 126:303-14.
    • (2008) Clin Immunol , vol.126 , pp. 303-314
    • King, M.1    Pearson, T.2    Shultz, L.D.3
  • 38
    • 67649580473 scopus 로고    scopus 로고
    • Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
    • Ito R, Katano I, Kawai K etal. Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice. Transplantation 2009; 87:1654-8.
    • (2009) Transplantation , vol.87 , pp. 1654-1658
    • Ito, R.1    Katano, I.2    Kawai, K.3
  • 40
    • 67649876115 scopus 로고    scopus 로고
    • New insights into the regulation of T cells by gamma(c) family cytokines
    • Rochman Y, Spolski R, Leonard WJ. New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol 2009; 9:480-90.
    • (2009) Nat Rev Immunol , vol.9 , pp. 480-490
    • Rochman, Y.1    Spolski, R.2    Leonard, W.J.3
  • 41
    • 68949086608 scopus 로고    scopus 로고
    • Selective reduction of graft-versus-host disease-mediating human T cells by ex vivo treatment with soluble Fas ligand
    • Bohana-Kashtan O, Morisot S, Hildreth R, Brayton C, Levitsky HI, Civin CI. Selective reduction of graft-versus-host disease-mediating human T cells by ex vivo treatment with soluble Fas ligand. J Immunol 2009; 183:696-705.
    • (2009) J Immunol , vol.183 , pp. 696-705
    • Bohana-Kashtan, O.1    Morisot, S.2    Hildreth, R.3    Brayton, C.4    Levitsky, H.I.5    Civin, C.I.6
  • 42
    • 53149092106 scopus 로고    scopus 로고
    • CD28 costimulation is essential for human T regulatory expansion and function
    • Golovina TN, Mikheeva T, Suhoski MM etal. CD28 costimulation is essential for human T regulatory expansion and function. J Immunol 2008; 181:2855-68.
    • (2008) J Immunol , vol.181 , pp. 2855-2868
    • Golovina, T.N.1    Mikheeva, T.2    Suhoski, M.M.3
  • 43
    • 63049129393 scopus 로고    scopus 로고
    • Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease
    • Wilson J, Cullup H, Lourie R etal. Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease. J Exp Med 2009; 206:387-98.
    • (2009) J Exp Med , vol.206 , pp. 387-398
    • Wilson, J.1    Cullup, H.2    Lourie, R.3
  • 44
    • 80053634727 scopus 로고    scopus 로고
    • Nomenclature and serology of HLA class I and class II alleles. In: Coligan JE, Kruisbeek AM, Margulies DM, Shevach EM, Strober W, eds. Current protocols in immunology. New Jersey: John Wiley & Sons, Appendix 1
    • McCluskey J, Kanaan C, Diviney M. Nomenclature and serology of HLA class I and class II alleles. In: Coligan JE, Kruisbeek AM, Margulies DM, Shevach EM, Strober W, eds. Current protocols in immunology. New Jersey: John Wiley & Sons, 2002:Appendix 1:S.1-S.8.
    • (2002)
    • McCluskey, J.1    Kanaan, C.2    Diviney, M.3
  • 45
    • 0028333939 scopus 로고
    • Human major histocompatibility complex class II-restricted T cell responses in transgenic mice
    • Woods A, Chen HY, Trumbauer ME, Sirotina A, Cummings R, Zaller DM. Human major histocompatibility complex class II-restricted T cell responses in transgenic mice. J Exp Med 1994; 180:173-81.
    • (1994) J Exp Med , vol.180 , pp. 173-181
    • Woods, A.1    Chen, H.Y.2    Trumbauer, M.E.3    Sirotina, A.4    Cummings, R.5    Zaller, D.M.6
  • 46
    • 1842844016 scopus 로고    scopus 로고
    • PCR-sequence-specific primer typing of HLA class I and class II alleles
    • Bunce M. PCR-sequence-specific primer typing of HLA class I and class II alleles. Methods Mol Biol 2003; 210:143-71.
    • (2003) Methods Mol Biol , vol.210 , pp. 143-171
    • Bunce, M.1
  • 47
    • 33846248643 scopus 로고    scopus 로고
    • Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice
    • Brehm MA, Mangada J, Markees TG etal. Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice. Blood 2007; 109:819-26.
    • (2007) Blood , vol.109 , pp. 819-826
    • Brehm, M.A.1    Mangada, J.2    Markees, T.G.3
  • 48
    • 77449117725 scopus 로고    scopus 로고
    • Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease
    • Pino S, Brehm MA, Covassin-Barberis L etal. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol 2010; 602:105-17.
    • (2010) Methods Mol Biol , vol.602 , pp. 105-117
    • Pino, S.1    Brehm, M.A.2    Covassin-Barberis, L.3
  • 49
    • 77749313682 scopus 로고    scopus 로고
    • NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection
    • Racki WJ, Covassin L, Brehm M etal. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation 2010; 89:527-36.
    • (2010) Transplantation , vol.89 , pp. 527-536
    • Racki, W.J.1    Covassin, L.2    Brehm, M.3
  • 50
    • 33947726614 scopus 로고    scopus 로고
    • How a single T cell receptor recognizes both self and foreign MHC
    • Colf LA, Bankovich AJ, Hanick NA etal. How a single T cell receptor recognizes both self and foreign MHC. Cell 2007; 129:135-46.
    • (2007) Cell , vol.129 , pp. 135-146
    • Colf, L.A.1    Bankovich, A.J.2    Hanick, N.A.3
  • 51
    • 22744441535 scopus 로고    scopus 로고
    • How the T cell repertoire becomes peptide and MHC specific
    • Huseby ES, White J, Crawford F etal. How the T cell repertoire becomes peptide and MHC specific. Cell 2005; 122:247-60.
    • (2005) Cell , vol.122 , pp. 247-260
    • Huseby, E.S.1    White, J.2    Crawford, F.3
  • 52
    • 34248572342 scopus 로고    scopus 로고
    • Alloreactive T cells respond specifically to multiple distinct peptide-MHC complexes
    • Felix NJ, Donermeyer DL, Horvath S etal. Alloreactive T cells respond specifically to multiple distinct peptide-MHC complexes. Nat Immunol 2007; 8:388-97.
    • (2007) Nat Immunol , vol.8 , pp. 388-397
    • Felix, N.J.1    Donermeyer, D.L.2    Horvath, S.3
  • 53
    • 34948850833 scopus 로고    scopus 로고
    • In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice
    • Jarchum I, Baker JC, Yamada T etal. In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice. Diabetes 2007; 56:2551-60.
    • (2007) Diabetes , vol.56 , pp. 2551-2560
    • Jarchum, I.1    Baker, J.C.2    Yamada, T.3
  • 54
    • 33644501795 scopus 로고    scopus 로고
    • HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes
    • Takaki T, Marron MP, Mathews CE etal. HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol 2006; 176:3257-65.
    • (2006) J Immunol , vol.176 , pp. 3257-3265
    • Takaki, T.1    Marron, M.P.2    Mathews, C.E.3
  • 55
    • 34249107054 scopus 로고    scopus 로고
    • Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men
    • Unger WW, Pinkse GG, Mulder-van der Kracht S etal. Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men. Ann NY Acad Sci 2007; 1103:192-5.
    • (2007) Ann NY Acad Sci , vol.1103 , pp. 192-195
    • Unger, W.W.1    Pinkse, G.G.2    Mulder-van der Kracht, S.3
  • 56
    • 15844398106 scopus 로고    scopus 로고
    • HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis
    • Ito K, Bian HJ, Molina M etal. HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis. J Exp Med 1996; 183:2635-44.
    • (1996) J Exp Med , vol.183 , pp. 2635-2644
    • Ito, K.1    Bian, H.J.2    Molina, M.3
  • 57
    • 0033621150 scopus 로고    scopus 로고
    • Mice lacking all conventional MHC class II genes
    • Madsen L, Labrecque N, Engberg J etal. Mice lacking all conventional MHC class II genes. Proc Natl Acad Sci USA 1999; 96:10338-43.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10338-10343
    • Madsen, L.1    Labrecque, N.2    Engberg, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.