Familial Juvenile Onset Psoriasis Is Associated with the Human Leukocyte Antigen (HLA) Class I Side of the Extended Haplotype Cw6-B57-DRB1*0701-DQA1*0201-DQB1*0303: A Population- and Family-Based Study

Journal of Investigative Dermatology

Volumn 106, Issue 4, 1996, Pages 711-714

  Schmitt Egenolf, Marcus ^a,b   Eiermann, Thomas H ^c   Boehncke, Wolf Henning ^d   Ständer, Markward ^e   Sterry, Wolfram ^a,f  

^a HUMBOLDT UNIVERSITY   (Germany)

^b Universitatsklinik fur Dermatologie   (Austria)

^c Red Cross Blood Bank   (Germany)

^d UNIVERSITY OF ULM   (Germany)

^e Fachklinik Bad Bentheim   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Autoimmune disease; Disease susceptibility; Histocompatibility antigens; Polymerase chain reaction

Indexed keywords

HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FAMILIAL DISEASE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSORIASIS;

EID: 0029983734     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12345600     Document Type: Article

References (25)

1. Awdeh ZL, Raum D, Yunis EJ, Alper CA: Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man. Proc Nat Acad Sci USA 80:259-263, 1983
2. Ballas M, Oechsle G, Eiermann TH, Mueller C, Woelpl A, Goldmann SF: A DRB oligonucleotide typing system defining 51/56 DRB alleles. In: Aizawa M, Sasazuki T (eds.). HLA 1991. Vol. 2. Oxford University Press, Oxford, 1992
3. Brandrup F, Hauge M, Henningsen K, Eriksen B: Psoriasis in an unselected series of twins. Arch Dermatol 11-:874-878, 1978
4. Brenner W, Gschnait F, Mayr RW: ULA B13, B17, B37 and Cw6 in psoriasis vulgaris: association with the age of onset. Arch Dermatol Res 262:737-739, 1978
5. Christophers E, Henseler T Patient subgroups and the inflammatory pattern in psoriasis. Acta Dermatol Generol 69 (151 suppl):88S-92S, 1989
6. Dawkins RL, leaver A, Cameron PU, Martin E, Kay PH, Christiansen FT: Some disease associated ancestral haplotypes carry a polymorphism of TNF. Hum Immunol 20:91-97, 1989
7. Degli-Eposti MA, Leaver AL, Christianen FT, Witt CS, Abraham LJ, Dawkins RL: Ancestral haplotypex: conserved population MHC haplotypes. Hum Immunol 34:242-252, 1992
8. Dunn OJ: Multiple comparisons among means. Am J Stat Assoc 56:52-64, 1961
9. Eiermann TH, Fakler J, Müller CR, Ballas M, Goldmann SF: HLA-DPB1 oligonuleotide typing of a Southwest German Caucasian population. Tissue Antigens 38:193-198, 1991
10. Fakler JW, Schmitt-Egnolf M, Vejbaesja S, Boehncke WH, Sterry W. Eiermann TH: Analysis of TAP2 and HLA-DP gene polymorphism in psoriasis. Hum Immunol 40:299-302, 1994
11. Farber EM, Bright RD, Nall ML: Psoriasis: a questionnaire survey of 2,144 patients. Arch Dermatol 98:248-259, 1968
12. Haldane JBS: The estimation and significance of the logarithm of the logarithm of a ratio of frequencies. Ann Hum Genet 20:309-311, 1955
13. Hanson IM, Poustka A, Trowsdale J: News genes in the class II region of the human major histocompatibility complex. Genomics 10:417-424, 1991
14. Henseler T, Christophers E: Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 13:450-456, 1985
15. Nepom GT, Ehrlich H: MHC class-II molecules and autoimmunity. Annu Rev Immunol 9:493-525, 1991
16. Russel TJ, Schultes LM, Kuban DJ: Histocompatibility (HL-A) antigens associated with psoriasis. N Engl J Med 287:738-740, 1972
17. Sargent CA, Dunham I, Campbell RD: Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. EMBO J 8:2305-2312, 1989
18. Schmitt-Egenolf M, Boehncke WH, Eiermann TH, Staender M, Sterry W: Oligonuleotide typing reveals association of type 1 psoriasis with the HLA-DRB1*0701/2,-DQA1*0201, -DQB1*0303 extended haplotype. J Invest Dermatol 100:749-752, 1993
19. Svejgaard A, Ryder LP: HLA and disease associations: detecting the strongest association. Tissue Antigens 43:18-27, 1994
20. Svejgaard A, Staub-Nielsen L, Svejgaard L, Kissmeyer Nielsen F, Hjortshoj A, Zachariae H: HL-A in psoriasis vulgaris and in pustular psoriasis: population and family studies. Br J Dermatol 91:145-153, 1974
21. Terasaki PI, Park MS: Microdroplet lymphocyte cytotoxicity test. In: Ray, Hare, Pedersen, Mullally (eds.). Manual of Tissue Typing Techniques. OHEW Publication No. (NIH) 76-545, 1986, pp. 69-80.
22. Tiwari JL, Lowe NJ, Abramovits W, Hawkins BR, Park MS: Association of psoriasis with HLA-DR7. Br J Deramtol 1016:227-230, 1982
23. Trowsdale J, Ragoussis J, Champbell RD: Map of the human MHC. Immunol Today 12:443-446, 1991
24. White SH, Newcomer VD, Mickey MR, Terasaki PI: Disturbance of HL-A antigen frequency in psoriasis. N Engl J Med 287:740-743, 1972
25. Woolf B: On estimating the relation between blood groups and disease. Ann Hum Genet 16:251-253, 1955