Epigenetic control of Foxp3 by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T-cell responses during pulmonary viral infection

Mucosal Immunology

Volumn 8, Issue 5, 2015, Pages 1131-1143

  Nagata, D E De Almeida ^a   Ting, H A ^a   Cavassani, K A ^a   Schaller, M A ^a   Mukherjee, S ^a   Ptaschinski, C ^a   Kunkel, S L ^a   Lukacs, N W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HISTONE METHYLTRANSFERASE; INTERLEUKIN 17; SMAD3 PROTEIN; SMYD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; SMYD3 PROTEIN, MOUSE; TGFB1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELLULAR IMMUNITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DNA SEQUENCE; EPIGENETICS; FEMALE; GENE LOCUS; GENE SILENCING; GENETIC REGULATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; MOUSE; MOUSE MODEL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; RESPIRATORY SYNCYTIAL VIRUS INFECTION; ANIMAL; GENETIC EPIGENESIS; GENETICS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG DISEASE; PATHOLOGY;

ANIMALS; EPIGENESIS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; INTERLEUKIN-17; LUNG DISEASES; MICE; MICE, KNOCKOUT; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84939532938     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.4     Document Type: Article

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