Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells

Phytomedicine

Volumn 22, Issue 10, 2015, Pages 946-951

  Kuete, Victor ^a,b   Fouotsa, Hugues ^c   Mbaveng, Armelle T ^b   Wiench, Benjamin ^a   Nkengfack, Augustin E ^c   Efferth, Thomas ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF DSCHANG   (Cameroon)

^c UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

1,3 Dimethoxy 10 methylacridone; Acridone; Apoptosis; Cytotoxicity; Furoquinoline; Multi drugresistance

Indexed keywords

1 HYDROXY 4 METHOXY 10 METHYLACRIDONE; 1,3 DIMETHOXY 10 METHYLACRIDONE; ACRIDONE DERIVATIVE; ALKALOID DERIVATIVE; CASPASE; DOXORUBICIN; EVOXANTHINE; FUROQUINOLINE; MONTROFOLINE; NOREVOXANTHINE; REACTIVE OXYGEN METABOLITE; RESAZURIN; UNCLASSIFIED DRUG; VINBLASTINE; ALKALOID; ANTINEOPLASTIC AGENT;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL LINE; CANCER RESISTANCE; COLON CARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; ENZYME ACTIVITY; FLOW CYTOMETRY; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IC50; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; RESAZURIN ASSAY; CELL CYCLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; METABOLISM; MULTIDRUG RESISTANCE; TUMOR CELL LINE;

ACRIDONES; ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; REACTIVE OXYGEN SPECIES;

EID: 84939458696     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.07.002     Document Type: Article

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