Cytotoxic compounds from the fruits of Uapaca togoensis towards multifactorial drug-resistant cancer cells

Planta Medica

Volumn 81, Issue 1, 2015, Pages 32-38

  Kuete, Victor ^a,b   Sandjo, Louis P ^c   Seukep, Jackson A ^b   Zeino, Maen ^a   Mbaveng, Armelle T ^b   Ngadjui, Bonaventure ^d   Efferth, Thomas ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF DSCHANG   (Cameroon)

^c FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^d UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

alkaloid; apoptosis; arborinine; cytotoxicity; Euphorbiaceae; Uapaca togoensis

Indexed keywords

11 OXO ALPHA AMYRYL ACETATE; 3 O BETA DEXTRO GLUCOPYRANOSYL SITOSTEROL; ARBORININ; BETA AMYRYL ACETATE; CASPASE; CYTOTOXIC AGENT; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; FUTOKADSURIN B; LUPEOL; METHANOL; MULTIDRUG RESISTANCE PROTEIN; POMOLIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VINBLASTINE; 11-OXO-ALPHA-AMYRYL ACETATE; ACRIDINES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARBORININE; BETA-AMYRYL ACETATE; LIGNANS; OLEANOLIC ACID; PENTACYCLIC TRITERPENES; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; TRITERPENES;

APOPTOSIS; ARTICLE; CANCER CELL LINE; CASPASE ASSAY; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; EUPHORBIACEAE; FLOW CYTOMETRY; FRUIT; HUMAN; HUMAN CELL; IC50; LEUKEMIA CELL LINE; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; PHYTOCHEMISTRY; UAPACA TOGOENSIS; ANALOGS AND DERIVATIVES; CELL LINE, TUMOR; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIAL, MITOCHONDRIAL; METABOLISM; MOLECULAR STRUCTURE;

EUPHORBIACEAE; UAPACA TOGOENSIS;

ACRIDINES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; EUPHORBIACEAE; HUMANS; INHIBITORY CONCENTRATION 50; LIGNANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; OLEANOLIC ACID; PENTACYCLIC TRITERPENES; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; TRITERPENES;

EID: 84919354925     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1383362     Document Type: Article

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