-
1
-
-
77957329119
-
Isoprenoid pathway optimization for Taxol precursor overproduction inEscherichia coli
-
Ajikumar, P.K., Xiao, W.H., Tyo, K.E., Wang, Y., Simeon, F., Leonard, E., Mucha, O., Phon, T.H., Pfeifer, B., Stephanopoulos, G., 2010. Isoprenoid pathway optimization for Taxol precursor overproduction inEscherichia coli. Science 330, 70-74.
-
(2010)
Science
, vol.330
, pp. 70-74
-
-
Ajikumar, P.K.1
Xiao, W.H.2
Tyo, K.E.3
Wang, Y.4
Simeon, F.5
Leonard, E.6
Mucha, O.7
Phon, T.H.8
Pfeifer, B.9
Stephanopoulos, G.10
-
2
-
-
84879829307
-
Metabolic engineering ofEscherichia colifor limonene and perillyl alcohol production
-
Alonso-Gutierrez, J., Chan, R., Batth, T.S., Adams, P.D., Keasling, J.D., Petzold, C.J., Lee, T.S., 2013. Metabolic engineering ofEscherichia colifor limonene and perillyl alcohol production. Metab. Eng. 19, 33-41.
-
(2013)
Metab. Eng
, vol.19
, pp. 33-41
-
-
Alonso-Gutierrez, J.1
Chan, R.2
Batth, T.S.3
Adams, P.D.4
Keasling, J.D.5
Petzold, C.J.6
Lee, T.S.7
-
3
-
-
22844452835
-
Construction of lycopeneoverproducingE. colistrains by combining systematic and combinatorial gene knockout targets
-
Alper, H., Miyaoku, K., Stephanopoulos, G., 2005. Construction of lycopeneoverproducingE. colistrains by combining systematic and combinatorial gene knockout targets. Nat. Biotechnol. 23, 612-616.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 612-616
-
-
Alper, H.1
Miyaoku, K.2
Stephanopoulos, G.3
-
4
-
-
50249115104
-
Dynamic metabolic engineering for increasing bioprocess productivity
-
Anesiadis, N., Cluett, W.R., Mahadevan, R., 2008. Dynamic metabolic engineering for increasing bioprocess productivity. Metab. Eng. 10, 255-266.
-
(2008)
Metab. Eng
, vol.10
, pp. 255-266
-
-
Anesiadis, N.1
Cluett, W.R.2
Mahadevan, R.3
-
5
-
-
53049097710
-
Metabolic engineering ofEscherichia colifor 1-butanol production
-
Atsumi, S., Cann, A.F., Connor, M.R., Shen, C.R., Smith, K.M., Brynildsen, M.P., Chou, K.J., Hanai, T., Liao, J.C., 2008a. Metabolic engineering ofEscherichia colifor 1-butanol production. Metab. Eng. 10, 305-311.
-
(2008)
Metab. Eng
, vol.10
, pp. 305-311
-
-
Atsumi, S.1
Cann, A.F.2
Connor, M.R.3
Shen, C.R.4
Smith, K.M.5
Brynildsen, M.P.6
Chou, K.J.7
Hanai, T.8
Liao, J.C.9
-
6
-
-
38049001166
-
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
-
Atsumi, S., Hanai, T., Liao, J.C., 2008b. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451, 86-89.
-
(2008)
Nature
, vol.451
, pp. 86-89
-
-
Atsumi, S.1
Hanai, T.2
Liao, J.C.3
-
7
-
-
0036193776
-
Golden Rice: introducing the beta-carotene biosynthesis pathway into rice endosperm by genetic engineering to defeat vitamin A deficiency
-
Beyer, P., Al-Babili, S., Ye, X., Lucca, P., Schaub, P., Welsch, R., Potrykus, I., 2002. Golden Rice: introducing the beta-carotene biosynthesis pathway into rice endosperm by genetic engineering to defeat vitamin A deficiency. J. Nutr. 132, 506S-510S.
-
(2002)
J. Nutr
, vol.132
, pp. 506S-510S
-
-
Beyer, P.1
Al-Babili, S.2
Ye, X.3
Lucca, P.4
Schaub, P.5
Welsch, R.6
Potrykus, I.7
-
8
-
-
84881141592
-
Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost?
-
Bhutta, Z.A., Das, J.K., Rizvi, A., Gaffey, M.F., Walker, N., Horton, S., Webb, P., Lartey, A., Black, R.E., Lancet Nutrition Interventions Review Group, Maternal and Child Nutrition Study Group, 2013. Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost? Lancet 382, 452-477.
-
(2013)
Lancet
, vol.382
, pp. 452-477
-
-
Bhutta, Z.A.1
Das, J.K.2
Rizvi, A.3
Gaffey, M.F.4
Walker, N.5
Horton, S.6
Webb, P.7
Lartey, A.8
Black, R.E.9
-
9
-
-
38349061342
-
Maternal and child undernutrition: global and regional exposures and health consequences
-
Black, R.E., Allen, L.H., Bhutta, Z.A., Caulfield, L.E., de Onis, M., Ezzati, M., Mathers, C., Rivera, J, 2008. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371, 243-260.
-
(2008)
Lancet
, vol.371
, pp. 243-260
-
-
Black, R.E.1
Allen, L.H.2
Bhutta, Z.A.3
Caulfield, L.E.4
de Onis, M.5
Ezzati, M.6
Mathers, C.7
Rivera, J.8
-
10
-
-
84881182352
-
Maternal and child undernutrition and overweight in low-income and middle-income countries
-
Black, R.E., Victora, C.G., Walker, S.P., Bhutta, Z.A., Christian, P., de Onis, M., Ezzati, M., Grantham-McGregor, S., Katz, J., Martorell, R., Uauy, R., 2013. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet 382, 427-451.
-
(2013)
Lancet
, vol.382
, pp. 427-451
-
-
Black, R.E.1
Victora, C.G.2
Walker, S.P.3
Bhutta, Z.A.4
Christian, P.5
de Onis, M.6
Ezzati, M.7
Grantham-McGregor, S.8
Katz, J.9
Martorell, R.10
Uauy, R.11
-
11
-
-
0032926864
-
ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA inEscherichia coli
-
Brocklehurst, K.R., Hobman, J.L., Lawley, B., Blank, L., Marshall, S.J., Brown, N.L., Morby, A.P., 1999. ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA inEscherichia coli. Mol. Microbiol. 31, 893-902.
-
(1999)
Mol. Microbiol
, vol.31
, pp. 893-902
-
-
Brocklehurst, K.R.1
Hobman, J.L.2
Lawley, B.3
Blank, L.4
Marshall, S.J.5
Brown, N.L.6
Morby, A.P.7
-
12
-
-
84859589886
-
Genetic switchboard for synthetic biology applications
-
Callura, J.M., Cantor, C.R., Collins, J.J., 2012. Genetic switchboard for synthetic biology applications. Proc. Natl. Acad. Sci. U.S.A. 109, 5850-5855.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 5850-5855
-
-
Callura, J.M.1
Cantor, C.R.2
Collins, J.J.3
-
13
-
-
76749151341
-
Improving NADPH availability for natural product biosynthesis inEscherichia coliby metabolic engineering
-
Chemler, J.A., Fowler, Z.L., McHugh, K.P., Koffas, M.A., 2010. Improving NADPH availability for natural product biosynthesis inEscherichia coliby metabolic engineering. Metab. Eng. 12, 96-104.
-
(2010)
Metab. Eng
, vol.12
, pp. 96-104
-
-
Chemler, J.A.1
Fowler, Z.L.2
McHugh, K.P.3
Koffas, M.A.4
-
14
-
-
77955980518
-
Integration of spore-based genetically engineered whole-cell sensing systems into portable centrifugal microfluidic platforms
-
Date, A., Pasini, P., Daunert, S., 2010. Integration of spore-based genetically engineered whole-cell sensing systems into portable centrifugal microfluidic platforms. Anal. Bioanal. Chem. 398, 349-356.
-
(2010)
Anal. Bioanal. Chem
, vol.398
, pp. 349-356
-
-
Date, A.1
Pasini, P.2
Daunert, S.3
-
15
-
-
84924140841
-
High crude violacein production from glucose byEscherichia coliengineered with interactive control of tryptophan pathway and violacein biosynthetic pathway
-
Fang, M.Y., Zhang, C., Yang, S., Cui, J.Y., Jiang, P.X., Lou, K., Wachi, M., Xing, X.H., 2015. High crude violacein production from glucose byEscherichia coliengineered with interactive control of tryptophan pathway and violacein biosynthetic pathway. Microb. Cell Fact. 14, 8.
-
(2015)
Microb. Cell Fact
, vol.14
, pp. 8
-
-
Fang, M.Y.1
Zhang, C.2
Yang, S.3
Cui, J.Y.4
Jiang, P.X.5
Lou, K.6
Wachi, M.7
Xing, X.H.8
-
16
-
-
0035128694
-
Precursor balancing for metabolic engineering of lycopene production in Escherichia coli
-
Farmer, W.R., Liao, J.C., 2001. Precursor balancing for metabolic engineering of lycopene production in Escherichia coli. Biotechnol. Prog. 17, 57-61.
-
(2001)
Biotechnol. Prog
, vol.17
, pp. 57-61
-
-
Farmer, W.R.1
Liao, J.C.2
-
17
-
-
3242736546
-
Zinc and the risk for infectious disease
-
Fischer Walker, C., Black, R.E., 2004. Zinc and the risk for infectious disease. Annu. Rev. Nutr. 24, 255-275.
-
(2004)
Annu. Rev. Nutr
, vol.24
, pp. 255-275
-
-
Fischer Walker, C.1
Black, R.E.2
-
18
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson, D.G., Young, L., Chuang, R.Y., Venter, J.C., Hutchison 3rd, C.A., Smith, H.O., 2009. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat. Methods 6, 343-345.
-
(2009)
Nat. Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
19
-
-
85027949257
-
Development of a broad-spectrumfluorescent heavy metal bacterial biosensor
-
Gireesh-Babu, P., Chaudhari, A., 2012. Development of a broad-spectrumfluorescent heavy metal bacterial biosensor. Mol. Biol. Rep. 39, 11225-11229.
-
(2012)
Mol. Biol. Rep
, vol.39
, pp. 11225-11229
-
-
Gireesh-Babu, P.1
Chaudhari, A.2
-
20
-
-
35748950715
-
Use of serum zinc concentration as an indicator of population zinc status
-
Hess, S.Y., Peerson, J.M., King, J.C., Brown, K.H., 2007. Use of serum zinc concentration as an indicator of population zinc status. Food Nutr. Bull. 28, S403-S429.
-
(2007)
Food Nutr. Bull
, vol.28
, pp. S403-S429
-
-
Hess, S.Y.1
Peerson, J.M.2
King, J.C.3
Brown, K.H.4
-
21
-
-
29144502422
-
Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach
-
Jin, Y.S., Alper, H., Yang, Y.T., Stephanopoulos, G., 2005. Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Appl. Environ. Microbiol. 71, 8249-8256.
-
(2005)
Appl. Environ. Microbiol
, vol.71
, pp. 8249-8256
-
-
Jin, Y.S.1
Alper, H.2
Yang, Y.T.3
Stephanopoulos, G.4
-
22
-
-
0017873437
-
Methods compared for determining zinc in serum byflame atomic absorption spectroscopy
-
Kelson, J.R., Shamberger, R.J., 1978. Methods compared for determining zinc in serum byflame atomic absorption spectroscopy. Clin. Chem. 24, 240-244.
-
(1978)
Clin. Chem
, vol.24
, pp. 240-244
-
-
Kelson, J.R.1
Shamberger, R.J.2
-
23
-
-
0036434580
-
The functional analysis of directed amino-acid alterations in ZntR fromEscherichia coli
-
Khan, S., Brocklehurst, K.R., Jones, G.W., Morby, A.P., 2002. The functional analysis of directed amino-acid alterations in ZntR fromEscherichia coli. Biochem. Biophys. Res. Commun. 299, 438-445.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.299
, pp. 438-445
-
-
Khan, S.1
Brocklehurst, K.R.2
Jones, G.W.3
Morby, A.P.4
-
24
-
-
2942614884
-
Programmable cells: interfacing natural and engineered gene networks
-
Kobayashi, H., Kaern, M., Araki, M., Chung, K., Gardner, T.S., Cantor, C.R., Collins, J.J., 2004. Programmable cells: interfacing natural and engineered gene networks. Proc. Natl. Acad. Sci. U.S.A. 101, 8414-8419.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 8414-8419
-
-
Kobayashi, H.1
Kaern, M.2
Araki, M.3
Chung, K.4
Gardner, T.S.5
Cantor, C.R.6
Collins, J.J.7
-
25
-
-
84890395226
-
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay
-
Lee, M.E., Aswani, A., Han, A.S., Tomlin, C.J., Dueber, J.E., 2013. Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay. Nucleic Acids Res. 41, 10668-10678.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 10668-10678
-
-
Lee, M.E.1
Aswani, A.2
Han, A.S.3
Tomlin, C.J.4
Dueber, J.E.5
-
26
-
-
33744518327
-
Engineering controllable protein degradation
-
McGinness, K.E., Baker, T.A., Sauer, R.T., 2006. Engineering controllable protein degradation. Mol. Cell 22, 701-707.
-
(2006)
Mol. Cell
, vol.22
, pp. 701-707
-
-
McGinness, K.E.1
Baker, T.A.2
Sauer, R.T.3
-
27
-
-
78049430020
-
Metabolic engineering ofSaccharomyces cerevisiaefor the biotechnological production of succinic acid
-
Raab, A.M., Gebhardt, G., Bolotina, N., Weuster-Botz, D., Lang, C., 2010. Metabolic engineering ofSaccharomyces cerevisiaefor the biotechnological production of succinic acid. Metab. Eng. 12, 518-525.
-
(2010)
Metab. Eng
, vol.12
, pp. 518-525
-
-
Raab, A.M.1
Gebhardt, G.2
Bolotina, N.3
Weuster-Botz, D.4
Lang, C.5
-
28
-
-
33645870422
-
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
-
Ro, D.K., Paradise, E.M., Ouellet, M., Fisher, K.J., Newman, K.L., Ndungu, J.M., Ho, K.A., Eachus, R.A., Ham, T.S., Kirby, J., Chang, M.C., Withers, S.T., Shiba, Y., Sarpong, R., Keasling, J.D., 2006. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440, 940-943.
-
(2006)
Nature
, vol.440
, pp. 940-943
-
-
Ro, D.K.1
Paradise, E.M.2
Ouellet, M.3
Fisher, K.J.4
Newman, K.L.5
Ndungu, J.M.6
Ho, K.A.7
Eachus, R.A.8
Ham, T.S.9
Kirby, J.10
Chang, M.C.11
Withers, S.T.12
Shiba, Y.13
Sarpong, R.14
Keasling, J.D.15
-
29
-
-
84884166429
-
Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein
-
Rodrigues, A.L., Trachtmann, N., Becker, J., Lohanatha, A.F., Blotenberg, J., Bolten, C.J., Korneli, C., de Souza Lima, A.O., Porto, L.M., Sprenger, G.A., Wittmann, C., 2013. Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. Metab. Eng. 20, 29-41.
-
(2013)
Metab. Eng
, vol.20
, pp. 29-41
-
-
Rodrigues, A.L.1
Trachtmann, N.2
Becker, J.3
Lohanatha, A.F.4
Blotenberg, J.5
Bolten, C.J.6
Korneli, C.7
de Souza Lima, A.O.8
Porto, L.M.9
Sprenger, G.A.10
Wittmann, C.11
-
30
-
-
45149118469
-
Engineering BioBrick vectors from BioBrick parts
-
Shetty, R.P., Endy, D., Knight Jr., T.F., 2008. Engineering BioBrick vectors from BioBrick parts. J. Biol. Eng. 2, 5.
-
(2008)
J. Biol. Eng
, vol.2
, pp. 5
-
-
Shetty, R.P.1
Endy, D.2
Knight, T.F.3
-
31
-
-
84869102255
-
A dynamic metabolite valve for the control of central carbon metabolism
-
Solomon, K.V., Sanders, T.M., Prather, K.L., 2012. A dynamic metabolite valve for the control of central carbon metabolism. Metab. Eng. 14, 661-671.
-
(2012)
Metab. Eng
, vol.14
, pp. 661-671
-
-
Solomon, K.V.1
Sanders, T.M.2
Prather, K.L.3
-
32
-
-
84899628032
-
Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch
-
Soma, Y., Tsuruno, K., Wada, M., Yokota, A., Hanai, T., 2014. Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch. Metab. Eng. 23, 175-184.
-
(2014)
Metab. Eng
, vol.23
, pp. 175-184
-
-
Soma, Y.1
Tsuruno, K.2
Wada, M.3
Yokota, A.4
Hanai, T.5
-
33
-
-
84879960190
-
Tailored fatty acid synthesis via dynamic control of fatty acid elongation
-
Torella, J.P., Ford, T.J., Kim, S.N., Chen, A.M., Way, J.C., Silver, P.A., 2013. Tailored fatty acid synthesis via dynamic control of fatty acid elongation. Proc. Natl. Acad. Sci. U.S.A. 110, 11290-11295.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 11290-11295
-
-
Torella, J.P.1
Ford, T.J.2
Kim, S.N.3
Chen, A.M.4
Way, J.C.5
Silver, P.A.6
-
34
-
-
77950858848
-
Autonomous induction of recombinant proteins by minimally rewiring native quorum sensing regulon ofE. coli
-
Tsao, C.Y., Hooshangi, S., Wu, H.C., Valdes, J.J., Bentley, W.E., 2010. Autonomous induction of recombinant proteins by minimally rewiring native quorum sensing regulon ofE. coli. Metab. Eng. 12, 291-297.
-
(2010)
Metab. Eng
, vol.12
, pp. 291-297
-
-
Tsao, C.Y.1
Hooshangi, S.2
Wu, H.C.3
Valdes, J.J.4
Bentley, W.E.5
-
35
-
-
84925639589
-
Quorum-sensing linked RNA interference for dynamic metabolic pathway control inSaccharomyces cerevisiae
-
Williams, T.C., Averesch, N.J., Winter, G., Plan, M.R., Vickers, C.E., Nielsen, L.K., Kromer, J.O., 2015. Quorum-sensing linked RNA interference for dynamic metabolic pathway control inSaccharomyces cerevisiae. Metab. Eng. 29, 124-134.
-
(2015)
Metab. Eng
, vol.29
, pp. 124-134
-
-
Williams, T.C.1
Averesch, N.J.2
Winter, G.3
Plan, M.R.4
Vickers, C.E.5
Nielsen, L.K.6
Kromer, J.O.7
-
36
-
-
56549092749
-
Egg beater as centrifuge: isolating human blood plasma from whole blood in resource-poor settings
-
Wong, A.P., Gupta, M., Shevkoplyas, S.S., Whitesides, G.M., 2008. Egg beater as centrifuge: isolating human blood plasma from whole blood in resource-poor settings. Lab Chip 8, 2032-2037.
-
(2008)
Lab Chip
, vol.8
, pp. 2032-2037
-
-
Wong, A.P.1
Gupta, M.2
Shevkoplyas, S.S.3
Whitesides, G.M.4
-
37
-
-
24944583149
-
Transcriptional response ofEscherichia colito external zinc
-
Yamamoto, K., Ishihama, A., 2005. Transcriptional response ofEscherichia colito external zinc. J. Bacteriol. 187, 6333-6340.
-
(2005)
J. Bacteriol
, vol.187
, pp. 6333-6340
-
-
Yamamoto, K.1
Ishihama, A.2
-
38
-
-
0033983338
-
Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
-
Ye, X., Al-Babili, S., Kloti, A., Zhang, J., Lucca, P., Beyer, P., Potrykus, I., 2000. Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287, 303-305.
-
(2000)
Science
, vol.287
, pp. 303-305
-
-
Ye, X.1
Al-Babili, S.2
Kloti, A.3
Zhang, J.4
Lucca, P.5
Beyer, P.6
Potrykus, I.7
-
39
-
-
33747127865
-
Enhanced lycopene production inEscherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate
-
Yoon, S.H., Lee, Y.M., Kim, J.E., Lee, S.H., Lee, J.H., Kim, J.Y., Jung, K.H., Shin, Y.C., Keasling, J.D., Kim, S.W., 2006. Enhanced lycopene production inEscherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. Biotechnol. Bioeng. 94, 1025-1032.
-
(2006)
Biotechnol. Bioeng
, vol.94
, pp. 1025-1032
-
-
Yoon, S.H.1
Lee, Y.M.2
Kim, J.E.3
Lee, S.H.4
Lee, J.H.5
Kim, J.Y.6
Jung, K.H.7
Shin, Y.C.8
Keasling, J.D.9
Kim, S.W.10
-
40
-
-
84920992414
-
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds
-
Zalatan, J.G., Lee, M.E., Almeida, R., Gilbert, L.A., Whitehead, E.H., La Russa, M., Tsai, J. C., Weissman, J.S., Dueber, J.E., Qi, L.S., Lim, W.A., 2015. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell 160, 339-350.
-
(2015)
Cell
, vol.160
, pp. 339-350
-
-
Zalatan, J.G.1
Lee, M.E.2
Almeida, R.3
Gilbert, L.A.4
Whitehead, E.H.5
La Russa, M.6
Tsai, J.C.7
Weissman, J.S.8
Dueber, J.E.9
Qi, L.S.10
Lim, W.A.11
|