메뉴 건너뛰기




Volumn 34, Issue 27, 2015, Pages 3504-3513

Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOBESITY AGENT; G PROTEIN COUPLED RECEPTOR 120; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OMEGA 3 FATTY ACID; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; G PROTEIN COUPLED RECEPTOR; O3FAR1 PROTEIN, MOUSE;

EID: 84939417589     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.283     Document Type: Article
Times cited : (51)

References (37)
  • 1
    • 84893315829 scopus 로고    scopus 로고
    • Obesity and prostate cancer incidence and mortality: A systematic review of prospective cohort studies
    • Golabek T, Bukowczan J, Chlosta P, Powroznik J, Dobruch J, Borowka A. Obesity and prostate cancer incidence and mortality: a systematic review of prospective cohort studies. Urol Int 2014; 92: 7-14.
    • (2014) Urol Int , vol.92 , pp. 7-14
    • Golabek, T.1    Bukowczan, J.2    Chlosta, P.3    Powroznik, J.4    Dobruch, J.5    Borowka, A.6
  • 2
    • 84893436855 scopus 로고    scopus 로고
    • Risk factors for pancreatic cancer: Underlying mechanisms and potential targets
    • Kolodecik T, Shugrue C, Ashat M, Thrower EC. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Front Physiol 2013; 4: 415.
    • (2013) Front Physiol , vol.4 , pp. 415
    • Kolodecik, T.1    Shugrue, C.2    Ashat, M.3    Thrower, E.C.4
  • 3
    • 84888434121 scopus 로고    scopus 로고
    • Obesity and its impact on breast cancer: Tumor incidence, recurrence, survival, and possible interventions
    • Ligibel JA, Strickler HD. Obesity and its impact on breast cancer: tumor incidence, recurrence, survival, and possible interventions. Am Soc Clin Oncol Educ Book 2013; 52-59.
    • (2013) Am Soc Clin Oncol Educ Book , pp. 52-59
    • Ligibel, J.A.1    Strickler, H.D.2
  • 6
    • 70350645290 scopus 로고    scopus 로고
    • Influence of obesity on breast cancer receptor status and prognosis
    • Rose DP, Vona-Davis L. Influence of obesity on breast cancer receptor status and prognosis. Expert Rev Anticancer Ther 2009; 9: 1091-1101.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 1091-1101
    • Rose, D.P.1    Vona-Davis, L.2
  • 8
    • 77953742101 scopus 로고    scopus 로고
    • Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: Their role in the determination of nutritional requirements and chronic disease risk
    • Simopoulos AP. Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. Exp Biol Med 2010; 235: 785-795.
    • (2010) Exp Biol Med , vol.235 , pp. 785-795
    • Simopoulos, A.P.1
  • 9
    • 84880636087 scopus 로고    scopus 로고
    • Dietary fats and breast cancer risk
    • Khaw KT. Dietary fats and breast cancer risk. BMJ 2013; 347: f4518.
    • (2013) BMJ , vol.347 , pp. f4518
    • Khaw, K.T.1
  • 10
    • 80053381640 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer by fish oil in preclinical models: Trials and tribulations
    • Signori C, El-Bayoumy K, Russo J, Thompson HJ, Richie JP, Hartman TJ et al. Chemoprevention of breast cancer by fish oil in preclinical models: trials and tribulations. Cancer Res 2011; 71: 6091-6096.
    • (2011) Cancer Res , vol.71 , pp. 6091-6096
    • Signori, C.1    El-Bayoumy, K.2    Russo, J.3    Thompson, H.J.4    Richie, J.P.5    Hartman, T.J.6
  • 11
    • 84880599253 scopus 로고    scopus 로고
    • Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: Meta-analysis of data from 21 independent prospective cohort studies
    • Zheng JS, Hu XJ, Zhao YM, Yang J, Li D. Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies. BMJ 2013; 346: f3706.
    • (2013) BMJ , vol.346 , pp. f3706
    • Zheng, J.S.1    Hu, X.J.2    Zhao, Y.M.3    Yang, J.4    Li, D.5
  • 12
    • 84888261305 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and cancer
    • Jing K, Wu T, Lim K. Omega-3 polyunsaturated fatty acids and cancer. Anticancer Agents Med Chem 2013; 13: 1162-1177.
    • (2013) Anticancer Agents Med Chem , vol.13 , pp. 1162-1177
    • Jing, K.1    Wu, T.2    Lim, K.3
  • 13
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects
    • Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects. Cell 2010; 142: 687-698.
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3    Imamura, T.4    Morinaga, H.5    Fan, W.6
  • 14
    • 77952083245 scopus 로고    scopus 로고
    • Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice
    • Li P, Lu M, Nguyen MT, Bae EJ, Chapman J, Feng D et al. Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem 2010; 285: 15333-15345.
    • (2010) J Biol Chem , vol.285 , pp. 15333-15345
    • Li, P.1    Lu, M.2    Nguyen, M.T.3    Bae, E.J.4    Chapman, J.5    Feng, D.6
  • 15
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Ann Rev Physiol 2010; 72: 219-246.
    • (2010) Ann Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 16
    • 52649103422 scopus 로고    scopus 로고
    • Overexpression of TNF-alpha and TNFRII in invasive micropapillary carcinoma of the breast: Clinicopathological correlations
    • Cui LF, Guo XJ, Wei J, Liu FF, Fan Y, Lang RG et al. Overexpression of TNF-alpha and TNFRII in invasive micropapillary carcinoma of the breast: clinicopathological correlations. Histopathology 2008; 53: 381-388.
    • (2008) Histopathology , vol.53 , pp. 381-388
    • Cui, L.F.1    Guo, X.J.2    Wei, J.3    Liu, F.F.4    Fan, Y.5    Lang, R.G.6
  • 17
    • 0030905416 scopus 로고    scopus 로고
    • Serum concentration of tumor necrosis factor in patients with breast cancer
    • Sheen-Chen SM, Chen WJ, Eng HL, Chou FF. Serum concentration of tumor necrosis factor in patients with breast cancer. Breast Cancer Res Treat 1997; 43: 211-215.
    • (1997) Breast Cancer Res Treat , vol.43 , pp. 211-215
    • Sheen-Chen, S.M.1    Chen, W.J.2    Eng, H.L.3    Chou, F.F.4
  • 18
    • 84891801122 scopus 로고    scopus 로고
    • Prevention of obesity and insulin resistance by estrogens requires ERalpha activation function-2 (ERalphaAF-2), whereas ERalphaAF-1 is dispensable
    • Handgraaf S, Riant E, Fabre A, Waget A, Burcelin R, Liere P et al. Prevention of obesity and insulin resistance by estrogens requires ERalpha activation function-2 (ERalphaAF-2), whereas ERalphaAF-1 is dispensable. Diabetes 2013; 62: 4098-4108.
    • (2013) Diabetes , vol.62 , pp. 4098-4108
    • Handgraaf, S.1    Riant, E.2    Fabre, A.3    Waget, A.4    Burcelin, R.5    Liere, P.6
  • 19
    • 79955862214 scopus 로고    scopus 로고
    • Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
    • Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK et al. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev Res 2011; 4: 329-346.
    • (2011) Cancer Prev Res , vol.4 , pp. 329-346
    • Subbaramaiah, K.1    Howe, L.R.2    Bhardwaj, P.3    Du, B.4    Gravaghi, C.5    Yantiss, R.K.6
  • 20
    • 77951769605 scopus 로고    scopus 로고
    • Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer
    • Healy LA, Ryan AM, Carroll P, Ennis D, Crowley V, Boyle T et al. Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer. Clin Oncol 2010; 22: 281-288.
    • (2010) Clin Oncol , vol.22 , pp. 281-288
    • Healy, L.A.1    Ryan, A.M.2    Carroll, P.3    Ennis, D.4    Crowley, V.5    Boyle, T.6
  • 21
    • 81455143912 scopus 로고    scopus 로고
    • Obesity, inflammation, and postmenopausal breast cancer: Therapeutic implications
    • Maccio A, Madeddu C. Obesity, inflammation, and postmenopausal breast cancer: therapeutic implications. Sci World J 2011; 11: 2020-2036.
    • (2011) Sci World J , vol.11 , pp. 2020-2036
    • MacCio, A.1    Madeddu, C.2
  • 22
    • 84876879033 scopus 로고    scopus 로고
    • Minireview: Obesity and breast cancer: A tale of inflammation and dysregulated metabolism
    • Simpson ER, Brown KA. Minireview: obesity and breast cancer: a tale of inflammation and dysregulated metabolism. Mol Endocrinol 2013; 27: 715-725.
    • (2013) Mol Endocrinol , vol.27 , pp. 715-725
    • Simpson, E.R.1    Brown, K.A.2
  • 23
    • 70350482557 scopus 로고    scopus 로고
    • Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen speciesdependent manner
    • Wong SW, Kwon MJ, Choi AM, Kim HP, Nakahira K, Hwang DH. Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen speciesdependent manner. J Biol Chem 2009; 284: 27384-27392.
    • (2009) J Biol Chem , vol.284 , pp. 27384-27392
    • Wong, S.W.1    Kwon, M.J.2    Choi, A.M.3    Kim, H.P.4    Nakahira, K.5    Hwang, D.H.6
  • 24
    • 84892613976 scopus 로고    scopus 로고
    • Influence of omega-3 fatty acids on Tamoxifen-induced suppression of rat mammary carcinogenesis
    • Manni A, Richie JP Jr, Xu H, Washington S, Aliaga C, Bruggeman R et al. Influence of omega-3 fatty acids on Tamoxifen-induced suppression of rat mammary carcinogenesis. Int J Cancer 2014; 134: 1549-1557.
    • (2014) Int J Cancer , vol.134 , pp. 1549-1557
    • Manni, A.1    Richie, Jr.J.P.2    Xu, H.3    Washington, S.4    Aliaga, C.5    Bruggeman, R.6
  • 26
    • 84864198388 scopus 로고    scopus 로고
    • A liver full of JNK: Signaling in regulation of cell function and disease pathogenesis, and clinical approaches
    • Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology 2012; 143: 307-320.
    • (2012) Gastroenterology , vol.143 , pp. 307-320
    • Seki, E.1    Brenner, D.A.2    Karin, M.3
  • 27
    • 84899439688 scopus 로고    scopus 로고
    • The role of chronic inflammation in obesity-associated cancers
    • Ramos-Nino ME. The role of chronic inflammation in obesity-associated cancers. ISRN Oncol 2013; 2013: 697521.
    • (2013) ISRN Oncol , vol.2013 , pp. 697521
    • Ramos-Nino, M.E.1
  • 28
    • 84890316374 scopus 로고    scopus 로고
    • Obesity, metabolism and the microenvironment: Links to cancer
    • Sundaram S, Johnson AR, Makowski L. Obesity, metabolism and the microenvironment: links to cancer. J Carcinog 2013; 12: 19.
    • (2013) J Carcinog , vol.12 , pp. 19
    • Sundaram, S.1    Johnson, A.R.2    Makowski, L.3
  • 29
    • 84877252654 scopus 로고    scopus 로고
    • Experimental evidence of omega-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: Their potential role in inflammatory, neurodegenerative, and neoplastic diseases
    • Calviello G, Su HM, Weylandt KH, Fasano E, Serini S, Cittadini A. Experimental evidence of omega-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseases. Biomed Res Int 2013; 2013: 743171.
    • (2013) Biomed Res Int , vol.2013 , pp. 743171
    • Calviello, G.1    Su, H.M.2    Weylandt, K.H.3    Fasano, E.4    Serini, S.5    Cittadini, A.6
  • 30
    • 84861206960 scopus 로고    scopus 로고
    • New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids
    • de Lorgeril M, Salen P. New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids. BMC Med 2012; 10: 50.
    • (2012) BMC Med , vol.10 , pp. 50
    • De Lorgeril, M.1    Salen, P.2
  • 31
    • 84884353137 scopus 로고    scopus 로고
    • Omega-3 fatty acids for the prevention of breast cancer: An update and state of the science
    • Iyengar NM, Hudis CA, Gucalp A. Omega-3 fatty acids for the prevention of breast cancer: an update and state of the science. Curr Breast Cancer Rep 2013; 5: 247-254.
    • (2013) Curr Breast Cancer Rep , vol.5 , pp. 247-254
    • Iyengar, N.M.1    Hudis, C.A.2    Gucalp, A.3
  • 32
    • 84873686894 scopus 로고    scopus 로고
    • Dietary intake of specific fatty acids and breast cancer risk among postmenopausal women in the VITAL cohort
    • Sczaniecka AK, Brasky TM, Lampe JW, Patterson RE, White E. Dietary intake of specific fatty acids and breast cancer risk among postmenopausal women in the VITAL cohort. Nutr Cancer 2012; 64: 1131-1142.
    • (2012) Nutr Cancer , vol.64 , pp. 1131-1142
    • Sczaniecka, A.K.1    Brasky, T.M.2    Lampe, J.W.3    Patterson, R.E.4    White, E.5
  • 33
    • 77956395707 scopus 로고    scopus 로고
    • Docosahexaenoic acid induces apoptosis in MCF-7 cells in vitro and in vivo via reactive oxygen species formation and caspase 8 activation
    • Kang KS, Wang P, Yamabe N, Fukui M, Jay T, Zhu BT. Docosahexaenoic acid induces apoptosis in MCF-7 cells in vitro and in vivo via reactive oxygen species formation and caspase 8 activation. PLoS ONE 2010; 5: e10296.
    • (2010) PLoS ONE , vol.5 , pp. e10296
    • Kang, K.S.1    Wang, P.2    Yamabe, N.3    Fukui, M.4    Jay, T.5    Zhu, B.T.6
  • 34
    • 84870456254 scopus 로고    scopus 로고
    • Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids
    • MacLennan MB, Clarke SE, Perez K, Wood GA, Muller WJ, Kang JX et al. Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids. J Nutr Biochem 2013; 24: 388-395.
    • (2013) J Nutr Biochem , vol.24 , pp. 388-395
    • MacLennan, M.B.1    Clarke, S.E.2    Perez, K.3    Wood, G.A.4    Muller, W.J.5    Kang, J.X.6
  • 35
    • 84892546031 scopus 로고    scopus 로고
    • Docosahexaenoic acid inhibited the Wnt/beta-catenin pathway and suppressed breast cancer cells in vitro and in vivo
    • Xue M, Wang Q, Zhao J, Dong L, Ge Y, Hou L et al. Docosahexaenoic acid inhibited the Wnt/beta-catenin pathway and suppressed breast cancer cells in vitro and in vivo. J Nutr Biochem 2014; 25: 104-110.
    • (2014) J Nutr Biochem , vol.25 , pp. 104-110
    • Xue, M.1    Wang, Q.2    Zhao, J.3    Dong, L.4    Ge, Y.5    Hou, L.6
  • 36
    • 84890548520 scopus 로고    scopus 로고
    • Identification of G-proteincoupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma
    • Wu Q, Wang H, Zhao X, Shi Y, Jin M, Wan B et al. Identification of G-proteincoupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma. Oncogene 2013; 32: 5541-5550.
    • (2013) Oncogene , vol.32 , pp. 5541-5550
    • Wu, Q.1    Wang, H.2    Zhao, X.3    Shi, Y.4    Jin, M.5    Wan, B.6
  • 37
    • 84896708967 scopus 로고    scopus 로고
    • Attenuation of TGF-beta signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model
    • Biswas T, Gu X, Yang J, Ellies LG, Sun LZ. Attenuation of TGF-beta signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model. Cancer Lett 2014; 346: 129-138.
    • (2014) Cancer Lett , vol.346 , pp. 129-138
    • Biswas, T.1    Gu, X.2    Yang, J.3    Ellies, L.G.4    Sun, L.Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.