메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

Evaluating cellular polyfunctionality with a novel polyfunctionality index

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 22;

EID: 84864456754     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042403     Document Type: Article
Times cited : (76)

References (43)
  • 1
    • 34648828497 scopus 로고    scopus 로고
    • PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status
    • Sauce D, Almeida JR, Larsen M, Haro L, Autran B, et al. (2007) PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. AIDS 21: 2005-2013.
    • (2007) AIDS , vol.21 , pp. 2005-2013
    • Sauce, D.1    Almeida, J.R.2    Larsen, M.3    Haro, L.4    Autran, B.5
  • 2
    • 69449101948 scopus 로고    scopus 로고
    • Upregulation of interleukin 7 receptor alpha and programmed death 1 marks an epitope-specific CD8+ T-cell response that disappears following primary Epstein-Barr virus infection
    • Sauce D, Larsen M, Abbott RJ, Hislop AD, Leese AM, et al. (2009) Upregulation of interleukin 7 receptor alpha and programmed death 1 marks an epitope-specific CD8+ T-cell response that disappears following primary Epstein-Barr virus infection. J Virol 83: 9068-9078.
    • (2009) J Virol , vol.83 , pp. 9068-9078
    • Sauce, D.1    Larsen, M.2    Abbott, R.J.3    Hislop, A.D.4    Leese, A.M.5
  • 3
    • 67650581553 scopus 로고    scopus 로고
    • Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
    • Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, et al. (2009) Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113: 6351-6360.
    • (2009) Blood , vol.113 , pp. 6351-6360
    • Almeida, J.R.1    Sauce, D.2    Price, D.A.3    Papagno, L.4    Shin, S.Y.5
  • 4
    • 78650311033 scopus 로고    scopus 로고
    • Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine
    • Papagno L, Alter G, Assoumou L, Murphy RL, Garcia F, et al. (2011) Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine. AIDS 25: 27-36.
    • (2011) AIDS , vol.25 , pp. 27-36
    • Papagno, L.1    Alter, G.2    Assoumou, L.3    Murphy, R.L.4    Garcia, F.5
  • 5
    • 2442500442 scopus 로고    scopus 로고
    • The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration
    • Betts MR, Price DA, Brenchley JM, Lore K, Guenaga FJ, et al. (2004) The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. J Immunol 172: 6407-6417.
    • (2004) J Immunol , vol.172 , pp. 6407-6417
    • Betts, M.R.1    Price, D.A.2    Brenchley, J.M.3    Lore, K.4    Guenaga, F.J.5
  • 6
    • 77954080011 scopus 로고    scopus 로고
    • Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control
    • Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, et al. (2010) Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog 6: e1000917.
    • (2010) PLoS Pathog , vol.6
    • Hersperger, A.R.1    Pereyra, F.2    Nason, M.3    Demers, K.4    Sheth, P.5
  • 7
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781-4789.
    • (2006) Blood , vol.107 , pp. 4781-4789
    • Betts, M.R.1    Nason, M.C.2    West, S.M.3    De Rosa, S.C.4    Migueles, S.A.5
  • 8
    • 77955301737 scopus 로고    scopus 로고
    • Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment
    • Young JM, Adetifa IM, Ota MO, Sutherland JS, (2010) Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLoS One 5: e11237.
    • (2010) PLoS One , vol.5
    • Young, J.M.1    Adetifa, I.M.2    Ota, M.O.3    Sutherland, J.S.4
  • 9
    • 66149083973 scopus 로고    scopus 로고
    • Acquisition of polyfunctionality by Epstein-Barr virus-specific CD8+ T cells correlates with increased resistance to galectin-1-mediated suppression
    • Smith C, Beagley L, Khanna R, (2009) Acquisition of polyfunctionality by Epstein-Barr virus-specific CD8+ T cells correlates with increased resistance to galectin-1-mediated suppression. J Virol 83: 6192-6198.
    • (2009) J Virol , vol.83 , pp. 6192-6198
    • Smith, C.1    Beagley, L.2    Khanna, R.3
  • 10
    • 34250327922 scopus 로고    scopus 로고
    • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
    • Precopio ML, Betts MR, Parrino J, Price DA, Gostick E, et al. (2007) Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 204: 1405-1416.
    • (2007) J Exp Med , vol.204 , pp. 1405-1416
    • Precopio, M.L.1    Betts, M.R.2    Parrino, J.3    Price, D.A.4    Gostick, E.5
  • 12
    • 80054051707 scopus 로고    scopus 로고
    • Phenotypic analysis of perennial airborne allergen-specific CD4(+) T cells in atopic and non-atopic individuals
    • Crack LR, Chan HW, McPherson T, Ogg GS, (2011) Phenotypic analysis of perennial airborne allergen-specific CD4(+) T cells in atopic and non-atopic individuals. Clin Exp Allergy.
    • (2011) Clin Exp Allergy
    • Crack, L.R.1    Chan, H.W.2    McPherson, T.3    Ogg, G.S.4
  • 13
    • 77954493922 scopus 로고    scopus 로고
    • The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells
    • Mittag D, Scholzen A, Varese N, Baxter L, Paukovics G, et al. (2010) The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells. J Immunol 184: 4708-4716.
    • (2010) J Immunol , vol.184 , pp. 4708-4716
    • Mittag, D.1    Scholzen, A.2    Varese, N.3    Baxter, L.4    Paukovics, G.5
  • 14
    • 17644418352 scopus 로고    scopus 로고
    • Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals
    • Lindstedt M, Schiott A, Bengtsson A, Larsson K, Korsgren M, et al. (2005) Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals. Int Immunol 17: 401-409.
    • (2005) Int Immunol , vol.17 , pp. 401-409
    • Lindstedt, M.1    Schiott, A.2    Bengtsson, A.3    Larsson, K.4    Korsgren, M.5
  • 15
    • 80052143748 scopus 로고    scopus 로고
    • Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets
    • Larsen M, Arnaud L, Hie M, Parizot C, Dorgham K, et al. (2011) Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets. Eur J Immunol 41: 2596-2605.
    • (2011) Eur J Immunol , vol.41 , pp. 2596-2605
    • Larsen, M.1    Arnaud, L.2    Hie, M.3    Parizot, C.4    Dorgham, K.5
  • 16
    • 78650598765 scopus 로고    scopus 로고
    • The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors
    • Koup RA, Graham BS, Douek DC, (2010) The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors. Nat Rev Immunol 11: 65-70.
    • (2010) Nat Rev Immunol , vol.11 , pp. 65-70
    • Koup, R.A.1    Graham, B.S.2    Douek, D.C.3
  • 17
    • 38749096240 scopus 로고    scopus 로고
    • The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
    • Sekaly RP, (2008) The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J Exp Med 205: 7-12.
    • (2008) J Exp Med , vol.205 , pp. 7-12
    • Sekaly, R.P.1
  • 18
    • 44949154503 scopus 로고    scopus 로고
    • CD8+ T cell efficacy in vaccination and disease
    • Appay V, Douek DC, Price DA, (2008) CD8+ T cell efficacy in vaccination and disease. Nat Med 14: 623-628.
    • (2008) Nat Med , vol.14 , pp. 623-628
    • Appay, V.1    Douek, D.C.2    Price, D.A.3
  • 19
    • 64749112680 scopus 로고    scopus 로고
    • The role of IFN-gamma Elispot assay in HIV vaccine research
    • Streeck H, Frahm N, Walker BD, (2009) The role of IFN-gamma Elispot assay in HIV vaccine research. Nat Protoc 4: 461-469.
    • (2009) Nat Protoc , vol.4 , pp. 461-469
    • Streeck, H.1    Frahm, N.2    Walker, B.D.3
  • 20
    • 33847380680 scopus 로고    scopus 로고
    • A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses
    • Boulet S, Ndongala ML, Peretz Y, Boisvert MP, Boulassel MR, et al. (2007) A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses. J Immunol Methods 320: 18-29.
    • (2007) J Immunol Methods , vol.320 , pp. 18-29
    • Boulet, S.1    Ndongala, M.L.2    Peretz, Y.3    Boisvert, M.P.4    Boulassel, M.R.5
  • 21
    • 35548929000 scopus 로고    scopus 로고
    • Cell permeabilization for the assessment of T lymphocyte polyfunctional capacity
    • Papagno L, Almeida JR, Nemes E, Autran B, Appay V, (2007) Cell permeabilization for the assessment of T lymphocyte polyfunctional capacity. J Immunol Methods 328: 182-188.
    • (2007) J Immunol Methods , vol.328 , pp. 182-188
    • Papagno, L.1    Almeida, J.R.2    Nemes, E.3    Autran, B.4    Appay, V.5
  • 22
    • 84864460824 scopus 로고    scopus 로고
    • Samples isolated by Fluorescent Activated Cell Sorting (FACS)
    • Bosio A, Gerstmayer B, editors. Birkhauser
    • Appay V, Larsen M (2008) Samples isolated by Fluorescent Activated Cell Sorting (FACS). In: Progress in Inflammation Research - Microarrays in Inflammation. Bosio A, Gerstmayer B, editors. Birkhauser. 59-70.
    • (2008) Progress in Inflammation Research - Microarrays in Inflammation , pp. 59-70
    • Appay, V.1    Larsen, M.2
  • 23
    • 84856278095 scopus 로고    scopus 로고
    • Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8(+) T Cell Phenotypes
    • Newell EW, Sigal N, Bendall SC, Nolan GP, Davis MM, (2012) Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8(+) T Cell Phenotypes. Immunity.
    • (2012) Immunity
    • Newell, E.W.1    Sigal, N.2    Bendall, S.C.3    Nolan, G.P.4    Davis, M.M.5
  • 24
    • 79958122357 scopus 로고    scopus 로고
    • A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
    • Ma C, Fan R, Ahmad H, Shi Q, Comin-Anduix B, et al. (2011) A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat Med 17: 738-743.
    • (2011) Nat Med , vol.17 , pp. 738-743
    • Ma, C.1    Fan, R.2    Ahmad, H.3    Shi, Q.4    Comin-Anduix, B.5
  • 25
    • 79251515158 scopus 로고    scopus 로고
    • SPICE: Exploration and analysis of post-cytometric complex multivariate datasets
    • Roederer M, Nozzi JL, Nason MX, (2011) SPICE: Exploration and analysis of post-cytometric complex multivariate datasets. Cytometry A 79A: 167-174.
    • (2011) Cytometry A , vol.79 A , pp. 167-174
    • Roederer, M.1    Nozzi, J.L.2    Nason, M.X.3
  • 26
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13: 843-850.
    • (2007) Nat Med , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5
  • 27
    • 65549087573 scopus 로고    scopus 로고
    • Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response
    • Rizzuto GA, Merghoub T, Hirschhorn-Cymerman D, Liu C, Lesokhin AM, et al. (2009) Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response. J Exp Med 206: 849-866.
    • (2009) J Exp Med , vol.206 , pp. 849-866
    • Rizzuto, G.A.1    Merghoub, T.2    Hirschhorn-Cymerman, D.3    Liu, C.4    Lesokhin, A.M.5
  • 28
    • 60549109302 scopus 로고    scopus 로고
    • Tumor progression inhibits the induction of multifunctionality in adoptively transferred tumor-specific CD8+ T cells
    • Imai N, Ikeda H, Tawara I, Shiku H, (2009) Tumor progression inhibits the induction of multifunctionality in adoptively transferred tumor-specific CD8+ T cells. Eur J Immunol 39: 241-253.
    • (2009) Eur J Immunol , vol.39 , pp. 241-253
    • Imai, N.1    Ikeda, H.2    Tawara, I.3    Shiku, H.4
  • 29
    • 58149483422 scopus 로고    scopus 로고
    • CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
    • Yuan J, Gnjatic S, Li H, Powel S, Gallardo HF, et al. (2008) CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit. Proc Natl Acad Sci U S A 105: 20410-20415.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20410-20415
    • Yuan, J.1    Gnjatic, S.2    Li, H.3    Powel, S.4    Gallardo, H.F.5
  • 30
    • 77955458613 scopus 로고    scopus 로고
    • Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis
    • Frey O, Meisel J, Hutloff A, Bonhagen K, Bruns L, et al. (2010) Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis. Ann Rheum Dis 69: 1495-1501.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1495-1501
    • Frey, O.1    Meisel, J.2    Hutloff, A.3    Bonhagen, K.4    Bruns, L.5
  • 31
    • 49449115544 scopus 로고    scopus 로고
    • Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
    • Jandus C, Bioley G, Rivals JP, Dudler J, Speiser D, et al. (2008) Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 58: 2307-2317.
    • (2008) Arthritis Rheum , vol.58 , pp. 2307-2317
    • Jandus, C.1    Bioley, G.2    Rivals, J.P.3    Dudler, J.4    Speiser, D.5
  • 32
    • 80052971466 scopus 로고    scopus 로고
    • Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression
    • Akinsiku OT, Bansal A, Sabbaj S, Heath SL, Goepfert PA, (2011) Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression. J Acquir Immune Defic Syndr 58: 132-140.
    • (2011) J Acquir Immune Defic Syndr , vol.58 , pp. 132-140
    • Akinsiku, O.T.1    Bansal, A.2    Sabbaj, S.3    Heath, S.L.4    Goepfert, P.A.5
  • 35
    • 77957944425 scopus 로고    scopus 로고
    • HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses
    • Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, et al. (2010) HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. J Virol 84: 11020-11029.
    • (2010) J Virol , vol.84 , pp. 11020-11029
    • Ferre, A.L.1    Hunt, P.W.2    McConnell, D.H.3    Morris, M.M.4    Garcia, J.C.5
  • 36
    • 84864004531 scopus 로고    scopus 로고
    • Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in burmese rhesus macaques
    • Nomura T, Yamamoto H, Shiino T, Takahashi N, Nakane T, et al. (2012) Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in burmese rhesus macaques. J Virol 86: 6481-6490.
    • (2012) J Virol , vol.86 , pp. 6481-6490
    • Nomura, T.1    Yamamoto, H.2    Shiino, T.3    Takahashi, N.4    Nakane, T.5
  • 37
    • 63349108208 scopus 로고    scopus 로고
    • Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation
    • Gasser O, Bihl F, Sanghavi S, Rinaldo C, Rowe D, et al. (2009) Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation. Am J Transplant 9: 794-803.
    • (2009) Am J Transplant , vol.9 , pp. 794-803
    • Gasser, O.1    Bihl, F.2    Sanghavi, S.3    Rinaldo, C.4    Rowe, D.5
  • 38
    • 70349664158 scopus 로고    scopus 로고
    • Evidence of premature immune aging in patients thymectomized during early childhood
    • Sauce D, Larsen M, Fastenackels S, Duperrier A, Keller M, et al. (2009) Evidence of premature immune aging in patients thymectomized during early childhood. J Clin Invest 119: 3070-3078.
    • (2009) J Clin Invest , vol.119 , pp. 3070-3078
    • Sauce, D.1    Larsen, M.2    Fastenackels, S.3    Duperrier, A.4    Keller, M.5
  • 39
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
    • (2007) J Exp Med , vol.204 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5
  • 40
    • 77955657060 scopus 로고    scopus 로고
    • Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality
    • Mkhwanazi N, Thobakgale CF, van der Stok M, Reddy S, Mncube Z, et al. (2010) Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality. Virology 405: 483-491.
    • (2010) Virology , vol.405 , pp. 483-491
    • Mkhwanazi, N.1    Thobakgale, C.F.2    van der Stok, M.3    Reddy, S.4    Mncube, Z.5
  • 41
    • 79955972414 scopus 로고    scopus 로고
    • Epithelial adhesion molecules can inhibit HIV-1-specific CD8 T-cell functions
    • Streeck H, Kwon DS, Pyo A, Flanders M, Chevalier MF, et al. (2011) Epithelial adhesion molecules can inhibit HIV-1-specific CD8 T-cell functions. Blood 117: 5112-5122.
    • (2011) Blood , vol.117 , pp. 5112-5122
    • Streeck, H.1    Kwon, D.S.2    Pyo, A.3    Flanders, M.4    Chevalier, M.F.5
  • 42
    • 76249090051 scopus 로고    scopus 로고
    • The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response
    • Akondy RS, Monson ND, Miller JD, Edupuganti S, Teuwen D, et al. (2009) The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. J Immunol 183: 7919-7930.
    • (2009) J Immunol , vol.183 , pp. 7919-7930
    • Akondy, R.S.1    Monson, N.D.2    Miller, J.D.3    Edupuganti, S.4    Teuwen, D.5
  • 43
    • 84944178665 scopus 로고
    • Hierarchical grouping to optimize an objective function
    • Ward J, (1963) Hierarchical grouping to optimize an objective function. J Am Stat Assoc 58: 236-244.
    • (1963) J Am Stat Assoc , vol.58 , pp. 236-244
    • Ward, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.