Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells

Thorax

Volumn 70, Issue 7, 2015, Pages 668-676

  Kistemaker, Loes E M ^a,b   Hiemstra, Pieter S ^c   Bos, I Sophie T ^a,b   Bouwman, Susanne ^a,b   Van Den Berge, Maarten ^b   Hylkema, Machteld N ^b   Meurs, Herman ^a,b   Kerstjens, Huib A M ^b   Gosens, Reinoud ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CARRIER PROTEIN; CHOLINE TRANSPORTER LIKE PROTEIN 1; CHOLINE TRANSPORTER LIKE PROTEIN 4; CHOLINESTERASE; HEPATOCYTE NUCLEAR FACTOR 3BETA; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; INTERLEUKIN 13; MUCIN 5AC; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; SPDEF PROTEIN; TIOTROPIUM BROMIDE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CHOLINERGIC RECEPTOR BLOCKING AGENT; MUC5AC PROTEIN, HUMAN; SCOPOLAMINE DERIVATIVE;

AIR; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CHOLINERGIC SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; GOBLET CELL; HISTOCHEMISTRY; HUMAN; HUMAN CELL; METAPLASIA; MUC5AC GENE; NON NEURONAL CHOLINERGIC SYSTEM; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

ACETYLCHOLINE; CELL DIFFERENTIATION; CELLS, CULTURED; CHOLINERGIC ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GOBLET CELLS; HUMANS; INTERLEUKIN-13; METAPLASIA; MUCIN 5AC; RESPIRATORY MUCOSA; SCOPOLAMINE DERIVATIVES; TRANSCRIPTION FACTORS;

EID: 84939217329     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2014-205731     Document Type: Article

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