Reversibly crosslinked hyaluronic acid nanoparticles for active targeting and intelligent delivery of doxorubicin to drug resistant CD44 + human breast tumor xenografts

Journal of Controlled Release

Volumn 205, Issue , 2015, Pages 144-154

  Zhong, Yinan ^a   Zhang, Jian ^a   Cheng, Ru ^a   Deng, Chao ^a   Meng, Fenghua ^a   Xie, Fang ^a   Zhong, Zhiyuan ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Cancer therapy; CD44 targeting; Crosslinked nanoparticles; Drug resistance; Hyaluronic acid; Reduction sensitive

Indexed keywords

ACID RESISTANCE; AMINO ACIDS; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; DISEASES; DRUG PRODUCTS; DRUG THERAPY; MAMMALS; NANOPARTICLES; ONCOLOGY; ORGANIC ACIDS; PHARMACODYNAMICS; TUMORS;

CANCER THERAPY; CD44-TARGETING; CROSSLINKED; DRUG RESISTANCE; INHIBITION OF TUMOR GROWTH; KAPLAN-MEIER SURVIVAL CURVES; MCF-7 HUMAN BREAST CANCER CELLS; PHYSIOLOGICAL CONDITION;

HYALURONIC ACID;

ANTINEOPLASTIC ANTIBIOTIC; CD44 PROTEIN, HUMAN; CROSS LINKING REAGENT; DOXORUBICIN; DRUG CARRIER; HERMES ANTIGEN; HYALURONIC ACID; L-LYSINE METHYL ESTER; LYSINE; NANOPARTICLE; THIOCTIC ACID;

ANALOGS AND DERIVATIVES; ANIMAL; BREAST NEOPLASMS; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; FEMALE; HUMAN; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; MCF 7 CELL LINE; MEDICINAL CHEMISTRY; METABOLISM; MOLECULARLY TARGETED THERAPY; NANOMEDICINE; NUDE MOUSE; PATHOLOGY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; TISSUE DISTRIBUTION; TUMOR VOLUME;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, CD44; BREAST NEOPLASMS; CHEMISTRY, PHARMACEUTICAL; CROSS-LINKING REAGENTS; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; HYALURONIC ACID; INJECTIONS, INTRAVENOUS; LYSINE; MCF-7 CELLS; MICE, NUDE; MOLECULAR TARGETED THERAPY; NANOMEDICINE; NANOPARTICLES; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THIOCTIC ACID; TISSUE DISTRIBUTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84939168669     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.01.012     Document Type: Article

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