메뉴 건너뛰기




Volumn 9, Issue 9, 2014, Pages

The TIR-domain containing adaptor TRAM is required for TLR7 mediated RANTES production

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; MYELOID DIFFERENTIATION FACTOR 88; RANTES; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2; TUMOR NECROSIS FACTOR ALPHA; CCL5 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; IRF3 PROTEIN, HUMAN; RESIQUIMOD; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TICAM2 PROTEIN, HUMAN; TLR7 PROTEIN, HUMAN; TNF PROTEIN, HUMAN;

EID: 84939140338     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107141     Document Type: Article
Times cited : (13)

References (38)
  • 1
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 2
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA, Bowie AG (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7: 353-364.
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 3
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
    • Kagan JC, Su T, Horng T, Chow A, Akira S, et al. (2008) TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol 9: 361-368.
    • (2008) Nat Immunol , vol.9 , pp. 361-368
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5
  • 4
    • 33748871187 scopus 로고    scopus 로고
    • The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
    • Carty M, Goodbody R, Schroder M, Stack J, Moynagh PN, et al. (2006) The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 7: 1074-1081.
    • (2006) Nat Immunol , vol.7 , pp. 1074-1081
    • Carty, M.1    Goodbody, R.2    Schroder, M.3    Stack, J.4    Moynagh, P.N.5
  • 5
    • 79951835542 scopus 로고    scopus 로고
    • Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-beta and RANTES production
    • Siednienko J, Gajanayake T, Fitzgerald KA, Moynagh P, Miggin SM (2011) Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-beta and RANTES production. J Immunol 186: 2514-2522.
    • (2011) J Immunol , vol.186 , pp. 2514-2522
    • Siednienko, J.1    Gajanayake, T.2    Fitzgerald, K.A.3    Moynagh, P.4    Miggin, S.M.5
  • 6
    • 79951815286 scopus 로고    scopus 로고
    • TLR3-mediated IFN-beta gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like
    • Siednienko J, Halle A, Nagpal K, Golenbock DT, Miggin SM (2010) TLR3-mediated IFN-beta gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like. Eur J Immunol 40: 3150-3160.
    • (2010) Eur J Immunol , vol.40 , pp. 3150-3160
    • Siednienko, J.1    Halle, A.2    Nagpal, K.3    Golenbock, D.T.4    Miggin, S.M.5
  • 7
    • 77954381441 scopus 로고    scopus 로고
    • TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5
    • Choi YJ, Im E, Pothoulakis C, Rhee SH (2010) TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5. J Biol Chem 285: 21382-21390.
    • (2010) J Biol Chem , vol.285 , pp. 21382-21390
    • Choi, Y.J.1    Im, E.2    Pothoulakis, C.3    Rhee, S.H.4
  • 8
    • 78549284013 scopus 로고    scopus 로고
    • TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells
    • Choi YJ, Im E, Chung HK, Pothoulakis C, Rhee SH (2010) TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells. J Biol Chem 285: 37570-37578.
    • (2010) J Biol Chem , vol.285 , pp. 37570-37578
    • Choi, Y.J.1    Im, E.2    Chung, H.K.3    Pothoulakis, C.4    Rhee, S.H.5
  • 9
    • 84862006672 scopus 로고    scopus 로고
    • TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88
    • Ohnishi H, Tochio H, Kato Z, Kawamoto N, Kimura T, et al. (2012) TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88. PLoS One 7: e38423.
    • (2012) PLoS One , vol.7 , pp. e38423
    • Ohnishi, H.1    Tochio, H.2    Kato, Z.3    Kawamoto, N.4    Kimura, T.5
  • 10
    • 0034456693 scopus 로고    scopus 로고
    • Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
    • Du X, Poltorak A, Wei Y, Beutler B (2000) Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 11: 362-371.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 362-371
    • Du, X.1    Poltorak, A.2    Wei, Y.3    Beutler, B.4
  • 11
    • 0036088492 scopus 로고    scopus 로고
    • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
    • Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, et al. (2002) Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 3: 499.
    • (2002) Nat Immunol , vol.3 , pp. 499
    • Jurk, M.1    Heil, F.2    Vollmer, J.3    Schetter, C.4    Krieg, A.M.5
  • 12
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, et al. (2002) Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3: 196-200.
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3    Sato, S.4    Sanjo, H.5
  • 13
    • 67349187318 scopus 로고    scopus 로고
    • Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells
    • Mancuso G, Gambuzza M, Midiri A, Biondo C, Papasergi S, et al. (2009) Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat Immunol 10: 587-594.
    • (2009) Nat Immunol , vol.10 , pp. 587-594
    • Mancuso, G.1    Gambuzza, M.2    Midiri, A.3    Biondo, C.4    Papasergi, S.5
  • 14
    • 84872350340 scopus 로고    scopus 로고
    • Regulation of TLR7/9 signaling in plasmacytoid dendritic cells
    • Bao M, Liu YJ (2013) Regulation of TLR7/9 signaling in plasmacytoid dendritic cells. Protein Cell 4: 40-52.
    • (2013) Protein Cell , vol.4 , pp. 40-52
    • Bao, M.1    Liu, Y.J.2
  • 15
    • 70349254607 scopus 로고    scopus 로고
    • TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type i IFN
    • Di Domizio J, Blum A, Gallagher-Gambarelli M, Molens JP, Chaperot L, et al. (2009) TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN. Blood 114: 1794-1802.
    • (2009) Blood , vol.114 , pp. 1794-1802
    • Di Domizio, J.1    Blum, A.2    Gallagher-Gambarelli, M.3    Molens, J.P.4    Chaperot, L.5
  • 16
    • 79951835542 scopus 로고    scopus 로고
    • Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-(beta) and RANTES production
    • Siednienko J, Gajanayake T, Fitzgerald KA, Moynagh P, Miggin SM (2011) Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-(beta) and RANTES production. J Immunol 186: 2514-2522.
    • (2011) J Immunol , vol.186 , pp. 2514-2522
    • Siednienko, J.1    Gajanayake, T.2    Fitzgerald, K.A.3    Moynagh, P.4    Miggin, S.M.5
  • 17
    • 84874230451 scopus 로고    scopus 로고
    • TRIF-Mediated TLR3 and TLR4 Signaling Is Negatively Regulated by ADAM15
    • Ahmed S, Maratha A, Butt AQ, Shevlin E, Miggin SM (2013) TRIF-Mediated TLR3 and TLR4 Signaling Is Negatively Regulated by ADAM15. J Immunol 190: 2217-2228.
    • (2013) J Immunol , vol.190 , pp. 2217-2228
    • Ahmed, S.1    Maratha, A.2    Butt, A.Q.3    Shevlin, E.4    Miggin, S.M.5
  • 18
    • 0242624622 scopus 로고    scopus 로고
    • TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
    • Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, et al. (2003) TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 4: 1144-1150.
    • (2003) Nat Immunol , vol.4 , pp. 1144-1150
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Uematsu, S.4    Hoshino, K.5
  • 19
    • 70349324347 scopus 로고    scopus 로고
    • MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3
    • Kenny EF, Talbot S, Gong M, Golenbock DT, Bryant CE, et al. (2009) MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3. J Immunol 183: 3642-3651.
    • (2009) J Immunol , vol.183 , pp. 3642-3651
    • Kenny, E.F.1    Talbot, S.2    Gong, M.3    Golenbock, D.T.4    Bryant, C.E.5
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 21
    • 78649883780 scopus 로고    scopus 로고
    • IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice
    • Carrigan SO, Junkins R, Yang YJ, Macneil A, Richardson C, et al. (2010) IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice. J Immunol 185: 3602-3609.
    • (2010) J Immunol , vol.185 , pp. 3602-3609
    • Carrigan, S.O.1    Junkins, R.2    Yang, Y.J.3    MacNeil, A.4    Richardson, C.5
  • 22
    • 77949940198 scopus 로고    scopus 로고
    • Intracellular toll-like receptors
    • Blasius AL, Beutler B (2010) Intracellular toll-like receptors. Immunity 32: 305-315.
    • (2010) Immunity , vol.32 , pp. 305-315
    • Blasius, A.L.1    Beutler, B.2
  • 23
    • 77249160271 scopus 로고    scopus 로고
    • Localisation and trafficking of Toll-like receptors: An important mode of regulation
    • McGettrick AF, O'Neill LA (2010) Localisation and trafficking of Toll-like receptors: an important mode of regulation. Curr Opin Immunol 22: 20-27.
    • (2010) Curr Opin Immunol , vol.22 , pp. 20-27
    • McGettrick, A.F.1    O'Neill, L.A.2
  • 24
    • 33646567507 scopus 로고    scopus 로고
    • The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
    • Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, et al. (2006) The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proc Natl Acad Sci U S A 103: 6299-6304.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6299-6304
    • Rowe, D.C.1    McGettrick, A.F.2    Latz, E.3    Monks, B.G.4    Gay, N.J.5
  • 25
    • 0141959224 scopus 로고    scopus 로고
    • LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
    • Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, et al. (2003) LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. J Exp Med 198: 1043-1055.
    • (2003) J Exp Med , vol.198 , pp. 1043-1055
    • Fitzgerald, K.A.1    Rowe, D.C.2    Barnes, B.J.3    Caffrey, D.R.4    Visintin, A.5
  • 26
    • 0345991221 scopus 로고    scopus 로고
    • TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to tolllike receptor 4 TICAM-1 that induces interferon-beta
    • Oshiumi H, Sasai M, Shida K, Fujita T, Matsumoto M, et al. (2003) TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to tolllike receptor 4 TICAM-1 that induces interferon-beta. J Biol Chem 278: 49751-49762.
    • (2003) J Biol Chem , vol.278 , pp. 49751-49762
    • Oshiumi, H.1    Sasai, M.2    Shida, K.3    Fujita, T.4    Matsumoto, M.5
  • 28
    • 84875065899 scopus 로고    scopus 로고
    • IRF-3, IRF-5, and IRF-7 coordinately regulate the type i IFN response in myeloid dendritic cells downstream of MAVS signaling
    • Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, et al. (2013) IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog 9: e1003118.
    • (2013) PLoS Pathog , vol.9 , pp. e1003118
    • Lazear, H.M.1    Lancaster, A.2    Wilkins, C.3    Suthar, M.S.4    Huang, A.5
  • 29
    • 84866148785 scopus 로고    scopus 로고
    • Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock
    • Rudd PA, Wilson J, Gardner J, Larcher T, Babarit C, et al. (2012) Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. J Virol 86: 9888-9898.
    • (2012) J Virol , vol.86 , pp. 9888-9898
    • Rudd, P.A.1    Wilson, J.2    Gardner, J.3    Larcher, T.4    Babarit, C.5
  • 30
    • 84870665996 scopus 로고    scopus 로고
    • Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type i interferon-mediated control of murine norovirus replication
    • Thackray LB, Duan E, Lazear HM, Kambal A, Schreiber RD, et al. (2012) Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type I interferon-mediated control of murine norovirus replication. J Virol 86: 13515-13523.
    • (2012) J Virol , vol.86 , pp. 13515-13523
    • Thackray, L.B.1    Duan, E.2    Lazear, H.M.3    Kambal, A.4    Schreiber, R.D.5
  • 31
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
    • (2005) Nature , vol.434 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5
  • 32
    • 20444380445 scopus 로고    scopus 로고
    • The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling
    • Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, et al. (2005) The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. J Biol Chem 280: 17005-17012.
    • (2005) J Biol Chem , vol.280 , pp. 17005-17012
    • Schoenemeyer, A.1    Barnes, B.J.2    Mancl, M.E.3    Latz, E.4    Goutagny, N.5
  • 33
    • 67349092199 scopus 로고    scopus 로고
    • TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway
    • Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, et al. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nat Immunol 10: 579-586.
    • (2009) Nat Immunol , vol.10 , pp. 579-586
    • Palsson-McDermott, E.M.1    Doyle, S.L.2    McGettrick, A.F.3    Hardy, M.4    Husebye, H.5
  • 34
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad P, Hacker H, Rutz M, Bauer S, Vabulas RM, et al. (2002) Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 32: 1958-1968.
    • (2002) Eur J Immunol , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Hacker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.M.5
  • 35
    • 0242391997 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
    • Heil F, Ahmad-Nejad P, Hemmi H, Hochrein H, Ampenberger F, et al. (2003) The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 33: 2987-2997.
    • (2003) Eur J Immunol , vol.33 , pp. 2987-2997
    • Heil, F.1    Ahmad-Nejad, P.2    Hemmi, H.3    Hochrein, H.4    Ampenberger, F.5
  • 36
    • 84889654582 scopus 로고    scopus 로고
    • Nucleic acids and endosomal pattern recognition: How to tell friend from foe?
    • Brencicova E, Diebold SS (2013) Nucleic acids and endosomal pattern recognition: how to tell friend from foe? Front Cell Infect Microbiol 3: 37.
    • (2013) Front Cell Infect Microbiol , vol.3 , pp. 37
    • Brencicova, E.1    Diebold, S.S.2
  • 37
    • 33748871535 scopus 로고    scopus 로고
    • New insights into the regulation of TLR signaling
    • Miggin SM, O'Neill LA (2006) New insights into the regulation of TLR signaling. J Leukoc Biol 80: 220-226.
    • (2006) J Leukoc Biol , vol.80 , pp. 220-226
    • Miggin, S.M.1    O'Neill, L.A.2
  • 38
    • 57449095648 scopus 로고    scopus 로고
    • Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications
    • Guiducci C, Coffman RL, Barrat FJ (2009) Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications. J Intern Med 265: 43-57.
    • (2009) J Intern Med , vol.265 , pp. 43-57
    • Guiducci, C.1    Coffman, R.L.2    Barrat, F.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.