Ghrelin promotes renal cell carcinoma metastasis via Snail activation and is associated with poor prognosis

Journal of Pathology

Volumn 237, Issue 1, 2015, Pages 50-61

  Lin, Tsung Chieh ^a   Liu, Yu Peng ^b   Chan, Yung Chieh ^a   Su, Chia Yi ^a   Lin, Yuan Feng ^c   Hsu, Shih Lan ^d   Yang, Chung Shi ^e   Hsiao, Michael ^a  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

E cadherin; ghrelin; metastasis; migration; renal cell carcinoma; Snail

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GHRELIN; GHRELIN RECEPTOR; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; THREONINE; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; WORTMANNIN; CADHERIN; CDH1 PROTEIN, HUMAN; GHRL PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ARTICLE; CANCER PROGNOSIS; CELL MIGRATION; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DISTANT METASTASIS; ENZYME PHOSPHORYLATION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; KIDNEY METASTASIS; LYMPH NODE METASTASIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING SITE; CELL MOTION; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; KIDNEY TUMOR; MALE; METABOLISM; MORTALITY; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHOSPHORYLATION; PROCEDURES; RNA INTERFERENCE; SCID MOUSE; SECONDARY; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; BINDING SITES; CADHERINS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GHRELIN; HUMANS; KIDNEY NEOPLASMS; MALE; MICE, INBRED NOD; MICE, SCID; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, GHRELIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84938991422     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4552     Document Type: Article

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