The molecular mechanism of leptin secretion and expression induced by aristolochic acid in kidney fibroblast

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Lin, Tsung Chieh ^a   Lee, Tien Chiang ^b   Hsu, Shih Lan ^b   Yang, Chung Shi ^a,c  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ARISTOLOCHIC ACID; CCAAT ENHANCER BINDING PROTEIN ALPHA; DNA; LEPTIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; RAPAMYCIN; SMALL INTERFERING RNA; ARISTOLOCHIC ACID I; CARCINOGEN; CCAAT ENHANCER BINDING PROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FIBROBLAST; HORMONE RELEASE; KIDNEY; MOLECULAR MECHANICS; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETION;

ANIMALS; ARISTOLOCHIC ACIDS; CARCINOGENS; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; KIDNEY; LEPTIN; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 79751492230     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016654     Document Type: Article

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