MIR retrotransposon sequences provide insulators to the human genome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 32, 2015, Pages E4428-E4437

  Wang, Jianrong ^a   Vicente García, Cristina ^b,c   Seruggia, Davide ^b,c   Moltó, Eduardo ^b,c   Fernandez Miñán, Ana ^d   Neto, Ana ^d   Lee, Elbert ^e   Gómez Skarmeta, José Luis ^d   Montoliu, Lluís ^b,c   Lunyak, Victoria V ^e   Jordan, I King ^a,f   Craig, Nancy L ^g  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^d Instituto de Salud Carlos III   (Spain)

^e Aelan Cell Technologies   (United States)

^f PanAmerican Bioinformatics Institute   (Colombia)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromatin; Gene regulation; Genomics; Insulators; Transposable elements

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; GROWTH HORMONE; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR CTCF; TRANSFER RNA; CHROMATIN; RETROPOSON;

ALU SEQUENCE; ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CHROMATIN; COMPARATIVE STUDY; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE REPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN GENOME; HUMAN TISSUE; IN VITRO STUDY; INSULATOR ELEMENT; MAMMALIAN WIDE INTERSPERSED REPEAT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; RETROPOSON; RNA SEQUENCE; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; T LYMPHOCYTE ACTIVATION; TISSUE SPECIFICITY; ZEBRA FISH; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGY; GENETICS; MAMMAL; METABOLISM; NUCLEOTIDE SEQUENCE; REPRODUCIBILITY; T LYMPHOCYTE;

EUKARYOTA; MAMMALIA;

ANIMALS; BASE SEQUENCE; CHROMATIN; COMPUTATIONAL BIOLOGY; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; INSULATOR ELEMENTS; MAMMALS; ORGAN SPECIFICITY; REPRODUCIBILITY OF RESULTS; RETROELEMENTS; T-LYMPHOCYTES;

EID: 84938930718     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1507253112     Document Type: Article

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