메뉴 건너뛰기




Volumn 40, Issue 5, 2012, Pages 1916-1927

A role for insulator elements in the regulation of gene expression response to hypoxia

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR;

EID: 84858387125     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr842     Document Type: Article
Times cited : (9)

References (54)
  • 1
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang, G. L., Jiang, B. H., Rue, E. A. and Semenza, G. L. (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl Acad. Sci. USA, 92, 5510-5514.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 2
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions.i Its stabilization by hypoxia depends on redox-induced changes
    • Salceda, S. and Caro, J. (1997) Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem., 272, 22642-22647.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 3
    • 0030787469 scopus 로고    scopus 로고
    • Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
    • Jiang, B. H., Zheng, J. Z., Leung, S. W., Roe, R. and Semenza, G. L. (1997) Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension. J. Biol. Chem., 272, 19253-19260.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19253-19260
    • Jiang, B.H.1    Zheng, J.Z.2    Leung, S.W.3    Roe, R.4    Semenza, G.L.5
  • 4
    • 0027427588 scopus 로고
    • Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
    • Wang, G. L. and Semenza, G. L. (1993) Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J. Biol. Chem., 268, 21513-21518.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21513-21518
    • Wang, G.L.1    Semenza, G.L.2
  • 5
    • 67650531089 scopus 로고    scopus 로고
    • Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
    • Mole, D. R., Blancher, C., Copley, R. R., Pollard, P. J., Gleadle, J. M., Ragoussis, J. and Ratcliffe, P. J. (2009) Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J. Biol. Chem., 284, 16767-16775.
    • (2009) J. Biol. Chem. , vol.284 , pp. 16767-16775
    • Mole, D.R.1    Blancher, C.2    Copley, R.R.3    Pollard, P.J.4    Gleadle, J.M.5    Ragoussis, J.6    Ratcliffe, P.J.7
  • 6
    • 63449103705 scopus 로고    scopus 로고
    • Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
    • Xia, X., Lemieux, M. E., Li, W., Carroll, J. S., Brown, M., Liu, X. S. and Kung, A. L. (2009) Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc. Natl Acad. Sci. USA, 106, 4260-4265.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 4260-4265
    • Xia, X.1    Lemieux, M.E.2    Li, W.3    Carroll, J.S.4    Brown, M.5    Liu, X.S.6    Kung, A.L.7
  • 7
    • 31444444162 scopus 로고    scopus 로고
    • Integration of oxygen signaling at the consensus HRE
    • Wenger, R. H., Stiehl, D. P. and Camenisch, G. (2005) Integration of oxygen signaling at the consensus HRE. Sci. STKE, 2005, re12.
    • (2005) Sci. STKE , vol.2005
    • Wenger, R.H.1    Stiehl, D.P.2    Camenisch, G.3
  • 8
    • 75349114759 scopus 로고    scopus 로고
    • Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia
    • Xia, X. and Kung, A. L. (2009) Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia. Genome Biol., 10, R113.
    • (2009) Genome Biol. , vol.10
    • Xia, X.1    Kung, A.L.2
  • 10
    • 77952300971 scopus 로고    scopus 로고
    • Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction
    • Ortiz-Barahona, A., Villar, D., Pescador, N., Amigo, J. and del Peso, L. (2010) Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res., 38, 2332-2345.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 2332-2345
    • Ortiz-Barahona, A.1    Villar, D.2    Pescador, N.3    Amigo, J.4    Del Peso, L.5
  • 11
    • 69049111041 scopus 로고    scopus 로고
    • An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
    • Benita, Y., Kikuchi, H., Smith, A. D., Zhang, M. Q., Chung, D. C. and Xavier, R. J. (2009) An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. Nucleic Acids Res., 37, 4587-4602.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 4587-4602
    • Benita, Y.1    Kikuchi, H.2    Smith, A.D.3    Zhang, M.Q.4    Chung, D.C.5    Xavier, R.J.6
  • 12
    • 75149141847 scopus 로고    scopus 로고
    • Mechanisms of transcription factor selectivity
    • Pan, Y., Tsai, C. J., Ma, B. and Nussinov, R. (2010) Mechanisms of transcription factor selectivity. Trends Genet., 26, 75-83.
    • (2010) Trends Genet. , vol.26 , pp. 75-83
    • Pan, Y.1    Tsai, C.J.2    Ma, B.3    Nussinov, R.4
  • 13
    • 0037311664 scopus 로고    scopus 로고
    • Eukaryotic transcriptional regulatory complexes: Cooperativity from near and afar
    • Ogata, K., Sato, K. and Tahirov, T. H. (2003) Eukaryotic transcriptional regulatory complexes: cooperativity from near and afar. Curr. Opin. Struct. Biol., 13, 40-48.
    • (2003) Curr. Opin. Struct. Biol. , vol.13 , pp. 40-48
    • Ogata, K.1    Sato, K.2    Tahirov, T.H.3
  • 14
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne, D., Maniatis, T. and Harrison, S. C. (2007) An atomic model of the interferon-beta enhanceosome. Cell, 129, 1111-1123.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 15
    • 0032880215 scopus 로고    scopus 로고
    • Transitional change in interaction between HIF-1 and HNF-4 in response to hypoxia
    • Zhang, W., Tsuchiya, T. and Yasukochi, Y. (1999) Transitional change in interaction between HIF-1 and HNF-4 in response to hypoxia. J. Hum. Genet., 44, 293-299.
    • (1999) J. Hum. Genet. , vol.44 , pp. 293-299
    • Zhang, W.1    Tsuchiya, T.2    Yasukochi, Y.3
  • 16
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP
    • Yamashita, K., Discher, D. J., Hu, J., Bishopric, N. H. and Webster, K. A. (2001) Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP. J. Biol. Chem., 276, 12645-12653.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12645-12653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3    Bishopric, N.H.4    Webster, K.A.5
  • 17
    • 33745274488 scopus 로고    scopus 로고
    • Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection
    • Aprelikova, O., Wood, M., Tackett, S., Chandramouli, G. V. and Barrett, J. C. (2006) Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection. Cancer Res., 66, 5641-5647.
    • (2006) Cancer Res. , vol.66 , pp. 5641-5647
    • Aprelikova, O.1    Wood, M.2    Tackett, S.3    Chandramouli, G.V.4    Barrett, J.C.5
  • 18
    • 35848938945 scopus 로고    scopus 로고
    • The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha
    • Hu, C. J., Sataur, A., Wang, L., Chen, H. and Simon, M. C. (2007) The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Mol. Biol. Cell, 18, 4528-4542.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4528-4542
    • Hu, C.J.1    Sataur, A.2    Wang, L.3    Chen, H.4    Simon, M.C.5
  • 19
    • 40849085514 scopus 로고    scopus 로고
    • FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
    • Lupien, M., Eeckhoute, J., Meyer, C. A., Wang, Q., Zhang, Y., Li, W., Carroll, J. S., Liu, X. S. and Brown, M. (2008) FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell, 132, 958-970.
    • (2008) Cell , vol.132 , pp. 958-970
    • Lupien, M.1    Eeckhoute, J.2    Meyer, C.A.3    Wang, Q.4    Zhang, Y.5    Li, W.6    Carroll, J.S.7    Liu, X.S.8    Brown, M.9
  • 20
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga, S. M. and Schaffner, W. (1989) CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev., 3, 612-619.
    • (1989) Genes Dev. , vol.3 , pp. 612-619
    • Iguchi-Ariga, S.M.1    Schaffner, W.2
  • 21
    • 24744470281 scopus 로고    scopus 로고
    • In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation
    • Perini, G., Diolaiti, D., Porro, A. and Della Valle, G. (2005) In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation. Proc. Natl Acad. Sci. USA, 102, 12117-12122.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 12117-12122
    • Perini, G.1    Diolaiti, D.2    Porro, A.3    Della Valle, G.4
  • 22
    • 0032079558 scopus 로고    scopus 로고
    • Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site
    • Wenger, R. H., Kvietikova, I., Rolfs, A., Camenisch, G. and Gassmann, M. (1998) Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur. J. Biochem., 253, 771-777.
    • (1998) Eur. J. Biochem. , vol.253 , pp. 771-777
    • Wenger, R.H.1    Kvietikova, I.2    Rolfs, A.3    Camenisch, G.4    Gassmann, M.5
  • 23
    • 33747453473 scopus 로고    scopus 로고
    • Insulators: Exploiting transcriptional and epigenetic mechanisms
    • Gaszner, M. and Felsenfeld, G. (2006) Insulators: exploiting transcriptional and epigenetic mechanisms. Nat. Rev. Genet., 7, 703-713.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 703-713
    • Gaszner, M.1    Felsenfeld, G.2
  • 24
    • 9444232851 scopus 로고    scopus 로고
    • Boundary elements and nuclear organization
    • Capelson, M. and Corces, V. G. (2004) Boundary elements and nuclear organization. Biol. Cell, 96, 617-629.
    • (2004) Biol. Cell , vol.96 , pp. 617-629
    • Capelson, M.1    Corces, V.G.2
  • 25
    • 70349521671 scopus 로고    scopus 로고
    • Boundaries in vertebrate genomes: Different solutions to adequately insulate gene expression domains
    • Molto, E., Fernandez, A. and Montoliu, L. (2009) Boundaries in vertebrate genomes: different solutions to adequately insulate gene expression domains. Brief. Funct. Genomic Proteomic., 8, 283-296.
    • (2009) Brief. Funct. Genomic Proteomic. , vol.8 , pp. 283-296
    • Molto, E.1    Fernandez, A.2    Montoliu, L.3
  • 32
    • 16644391315 scopus 로고    scopus 로고
    • Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element
    • Kawakami, K. (2004) Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element. Methods Cell Biol., 77, 201-222.
    • (2004) Methods Cell Biol. , vol.77 , pp. 201-222
    • Kawakami, K.1
  • 34
    • 0033453222 scopus 로고    scopus 로고
    • Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells
    • Recillas-Targa, F., Bell, A. C. and Felsenfeld, G. (1999) Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells. Proc. Natl Acad. Sci. USA, 96, 14354-14359.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 14354-14359
    • Recillas-Targa, F.1    Bell, A.C.2    Felsenfeld, G.3
  • 36
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • Bell, A. C., West, A. G. and Felsenfeld, G. (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell, 98, 387-396.
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 39
    • 0033958481 scopus 로고    scopus 로고
    • An Alu element from the K18 gene confers position-independent expression in transgenic mice
    • Willoughby, D. A., Vilalta, A. and Oshima, R. G. (2000) An Alu element from the K18 gene confers position-independent expression in transgenic mice. J. Biol. Chem., 275, 759-768.
    • (2000) J. Biol. Chem. , vol.275 , pp. 759-768
    • Willoughby, D.A.1    Vilalta, A.2    Oshima, R.G.3
  • 40
    • 0026651977 scopus 로고
    • Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice
    • McKnight, R. A., Shamay, A., Sankaran, L., Wall, R. J. and Hennighausen, L. (1992) Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice. Proc. Natl Acad. Sci. USA, 89, 6943-6947.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6943-6947
    • McKnight, R.A.1    Shamay, A.2    Sankaran, L.3    Wall, R.J.4    Hennighausen, L.5
  • 41
    • 0038292116 scopus 로고    scopus 로고
    • Hormone-induced modifications of the chromatin structure surrounding upstream regulatory regions conserved between the mouse and rabbit whey acidic protein genes
    • Millot, B., Montoliu, L., Fontaine, M. L., Mata, T. and Devinoy, E. (2003) Hormone-induced modifications of the chromatin structure surrounding upstream regulatory regions conserved between the mouse and rabbit whey acidic protein genes. Biochem. J., 372, 41-52.
    • (2003) Biochem. J. , vol.372 , pp. 41-52
    • Millot, B.1    Montoliu, L.2    Fontaine, M.L.3    Mata, T.4    Devinoy, E.5
  • 42
    • 44649199179 scopus 로고    scopus 로고
    • Boundaries. Boundaries. . Boundaries
    • Lunyak, V. V. (2008) Boundaries. Boundaries. . Boundaries. Curr. Opin. Cell Biol., 20, 281-287.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 281-287
    • Lunyak, V.V.1
  • 43
    • 0036467996 scopus 로고    scopus 로고
    • Insulators: Many functions, many mechanisms
    • West, A. G., Gaszner, M. and Felsenfeld, G. (2002) Insulators: many functions, many mechanisms. Genes Dev., 16, 271-288.
    • (2002) Genes Dev. , vol.16 , pp. 271-288
    • West, A.G.1    Gaszner, M.2    Felsenfeld, G.3
  • 44
    • 0036094107 scopus 로고    scopus 로고
    • Conserved CTCF insulator elements flank the mouse and human beta-globin loci
    • Farrell, C. M., West, A. G. and Felsenfeld, G. (2002) Conserved CTCF insulator elements flank the mouse and human beta-globin loci. Mol. Cell Biol., 22, 3820-3831.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 3820-3831
    • Farrell, C.M.1    West, A.G.2    Felsenfeld, G.3
  • 45
    • 0042978644 scopus 로고    scopus 로고
    • Visualization of chromatin domains created by the gypsy insulator of Drosophila
    • Byrd, K. and Corces, V. G. (2003) Visualization of chromatin domains created by the gypsy insulator of Drosophila. J. Cell Biol., 162, 565-574.
    • (2003) J. Cell Biol. , vol.162 , pp. 565-574
    • Byrd, K.1    Corces, V.G.2
  • 48
    • 67549119096 scopus 로고    scopus 로고
    • CTCF: Master weaver of the genome
    • Phillips, J. E. and Corces, V. G. (2009) CTCF: master weaver of the genome. Cell, 137, 1194-1211.
    • (2009) Cell , vol.137 , pp. 1194-1211
    • Phillips, J.E.1    Corces, V.G.2
  • 51
    • 33746657720 scopus 로고    scopus 로고
    • Systematic analysis of head-to-head gene organization: Evolutionary conservation and potential biological relevance
    • Li, Y. Y., Yu, H., Guo, Z. M., Guo, T. Q., Tu, K. and Li, Y. X. (2006) Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance. PLoS Comput. Biol., 2, e74.
    • (2006) PLoS Comput. Biol. , vol.2
    • Li, Y.Y.1    Yu, H.2    Guo, Z.M.3    Guo, T.Q.4    Tu, K.5    Li, Y.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.