메뉴 건너뛰기




Volumn 195, Issue 4, 2015, Pages 1427-1435

The B cell-stimulatory cytokines BLyS and April are elevated in human periodontitis and are required for b cell-dependent bone loss in experimental murine periodontitis

Author keywords

[No Author keywords available]

Indexed keywords

APRIL PROTEIN; B CELL ACTIVATING FACTOR; IMMUNOGLOBULIN KAPPA CHAIN; MESSENGER RNA;

EID: 84938922445     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500496     Document Type: Article
Times cited : (69)

References (55)
  • 1
    • 84971323731 scopus 로고    scopus 로고
    • Periodontitis: From microbial immune subversion to systemic inflammation
    • Hajishengallis, G. 2015. Periodontitis: from microbial immune subversion to systemic inflammation. Nat. Rev. Immunol. 15: 30-44.
    • (2015) Nat. Rev. Immunol. , vol.15 , pp. 30-44
    • Hajishengallis, G.1
  • 2
    • 84924630982 scopus 로고    scopus 로고
    • Polymicrobial synergy and dysbiosis in inflammatory disease
    • Lamont, R. J., and G. Hajishengallis. 2015. Polymicrobial synergy and dysbiosis in inflammatory disease. Trends Mol. Med. 21: 172-183.
    • (2015) Trends Mol. Med. , vol.21 , pp. 172-183
    • Lamont, R.J.1    Hajishengallis, G.2
  • 3
    • 84891372427 scopus 로고    scopus 로고
    • Immunomicrobial pathogenesis of periodontitis: Keystones, pathobionts, and host response
    • Hajishengallis, G. 2014. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 35: 3-11.
    • (2014) Trends Immunol. , vol.35 , pp. 3-11
    • Hajishengallis, G.1
  • 4
    • 78650083063 scopus 로고    scopus 로고
    • Destructive and protective roles of cytokines in periodontitis: A re-appraisal from host defense and tissue destruction viewpoints
    • Garlet, G. P. 2010. Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints. J. Dent. Res. 89: 1349-1363.
    • (2010) J. Dent. Res. , vol.89 , pp. 1349-1363
    • Garlet, G.P.1
  • 5
    • 33846045743 scopus 로고    scopus 로고
    • The role of T cells in periodontal disease: Homeostasis and autoimmunity
    • Gemmell, E., K. Yamazaki, and G. J. Seymour. 2007. The role of T cells in periodontal disease: homeostasis and autoimmunity. Periodontol. 2000 43: 14-40.
    • (2007) Periodontol. 2000 , vol.43 , pp. 14-40
    • Gemmell, E.1    Yamazaki, K.2    Seymour, G.J.3
  • 6
    • 49449085034 scopus 로고    scopus 로고
    • Cytokines that promote periodontal tissue destruction
    • Graves, D. 2008. Cytokines that promote periodontal tissue destruction. J. Periodontol. 79(8, Suppl.): 1585-1591.
    • (2008) J. Periodontol. , vol.79 , Issue.8 , pp. 1585-1591
    • Graves, D.1
  • 8
    • 84935112679 scopus 로고    scopus 로고
    • Cellular composition of long-standing gingivitis and periodontitis lesions
    • Thorbert-Mros, S., L. Larsson, and T. Berglundh. 2014. Cellular composition of long-standing gingivitis and periodontitis lesions. J. Periodontal Res. DOI: 10.1111/jre.12236.
    • (2014) J. Periodontal Res.
    • Thorbert-Mros, S.1    Larsson, L.2    Berglundh, T.3
  • 9
    • 34548570002 scopus 로고    scopus 로고
    • B cells in periodontitis: Friends or enemies?
    • Berglundh, T., M. Donati, and N. Zitzmann. 2007. B cells in periodontitis: friends or enemies? Periodontol. 2000 45: 51-66.
    • (2007) Periodontol 2000 , vol.45 , pp. 51-66
    • Berglundh, T.1    Donati, M.2    Zitzmann, N.3
  • 10
    • 33644855778 scopus 로고    scopus 로고
    • Host responses in maintaining periodontal health and determining periodontal disease
    • Schenkein, H. A. 2006. Host responses in maintaining periodontal health and determining periodontal disease. Periodontol. 2000 40: 77-93.
    • (2006) Periodontol. 2000 , vol.40 , pp. 77-93
    • Schenkein, H.A.1
  • 11
    • 0026650853 scopus 로고
    • Serum immunoglobulin G antibody to Porphyromonas gingivalis in rapidly progressive periodontitis: Titer, avidity, and subclass distribution
    • Whitney, C., J. Ant, B. Moncla, B. Johnson, R. C. Page, and D. Engel. 1992. Serum immunoglobulin G antibody to Porphyromonas gingivalis in rapidly progressive periodontitis: titer, avidity, and subclass distribution. Infect. Immun. 60: 2194-2200.
    • (1992) Infect. Immun. , vol.60 , pp. 2194-2200
    • Whitney, C.1    Ant, J.2    Moncla, B.3    Johnson, B.4    Page, R.C.5    Engel, D.6
  • 13
    • 0018239237 scopus 로고
    • Immunoglobulins and complement in human periodontitis
    • Toto, P. D., L. M. Lin, and A. W. Gargiulo. 1978. Immunoglobulins and complement in human periodontitis. J. Periodontol. 49: 631-634.
    • (1978) J. Periodontol. , vol.49 , pp. 631-634
    • Toto, P.D.1    Lin, L.M.2    Gargiulo, A.W.3
  • 17
    • 29644446802 scopus 로고    scopus 로고
    • Bacterial-responsive B lymphocytes induce periodontal bone resorption
    • Han, X., T. Kawai, J. W. Eastcott, and M. A. Taubman. 2006. Bacterial-responsive B lymphocytes induce periodontal bone resorption. J. Immunol. 176: 625-631.
    • (2006) J. Immunol. , vol.176 , pp. 625-631
    • Han, X.1    Kawai, T.2    Eastcott, J.W.3    Taubman, M.A.4
  • 21
    • 70249086961 scopus 로고    scopus 로고
    • Signalling crosstalk in B cells: Managing worth and need
    • Cancro, M. P. 2009. Signalling crosstalk in B cells: managing worth and need. Nat. Rev. Immunol. 9: 657-661.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 657-661
    • Cancro, M.P.1
  • 22
    • 0034764499 scopus 로고    scopus 로고
    • Biologically active April is secreted following intracellular processing in the Golgi apparatus by furin convertase
    • López-Fraga, M., R. Fernández, J. P. Albar, and M. Hahne. 2001. Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase. EMBO Rep. 2: 945-951.
    • (2001) EMBO Rep. , vol.2 , pp. 945-951
    • López-Fraga, M.1    Fernández, R.2    Albar, J.P.3    Hahne, M.4
  • 26
    • 80054875478 scopus 로고    scopus 로고
    • Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease
    • Rickert, R. C., J. Jellusova, and A. V. Miletic. 2011. Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease. Immunol. Rev. 244: 115-133.
    • (2011) Immunol. Rev. , vol.244 , pp. 115-133
    • Rickert, R.C.1    Jellusova, J.2    Miletic, A.V.3
  • 27
    • 84924383379 scopus 로고    scopus 로고
    • The enduring importance of animal models in understanding periodontal disease
    • Hajishengallis, G., R. J. Lamont, and D. T. Graves. 2015. The enduring importance of animal models in understanding periodontal disease. Virulence 6: 229-235.
    • (2015) Virulence , vol.6 , pp. 229-235
    • Hajishengallis, G.1    Lamont, R.J.2    Graves, D.T.3
  • 28
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura, D., J. Roes, R. Kühn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350: 423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 29
    • 84877871579 scopus 로고    scopus 로고
    • Cell junction remodeling in gingival tissue exposed to a microbial toxin
    • Damek-Poprawa, M., J. Korostoff, R. Gill, and J. M. DiRienzo. 2013. Cell junction remodeling in gingival tissue exposed to a microbial toxin. J. Dent. Res. 92: 518-523.
    • (2013) J. Dent. Res. , vol.92 , pp. 518-523
    • Damek-Poprawa, M.1    Korostoff, J.2    Gill, R.3    DiRienzo, J.M.4
  • 30
    • 77951732640 scopus 로고    scopus 로고
    • Immunoglobulin light chain immunohistochemistry revisited, with emphasis on reactive follicular hyperplasia versus follicular lymphoma
    • Weiss, L. M., S. Loera, and C. E. Bacchi. 2010. Immunoglobulin light chain immunohistochemistry revisited, with emphasis on reactive follicular hyperplasia versus follicular lymphoma. Appl. Immunohistochem. Mol. Morphol. 18: 199-205.
    • (2010) Appl. Immunohistochem. Mol. Morphol. , vol.18 , pp. 199-205
    • Weiss, L.M.1    Loera, S.2    Bacchi, C.E.3
  • 31
    • 38149006156 scopus 로고    scopus 로고
    • The use of rodent models to investigate host-bacteria interactions related to periodontal diseases
    • Graves, D. T., D. Fine, Y. T. Teng, T. E. Van Dyke, and G. Hajishengallis. 2008. The use of rodent models to investigate host-bacteria interactions related to periodontal diseases. J. Clin. Periodontol. 35: 89-105.
    • (2008) J. Clin. Periodontol. , vol.35 , pp. 89-105
    • Graves, D.T.1    Fine, D.2    Teng, Y.T.3    Van Dyke, T.E.4    Hajishengallis, G.5
  • 33
    • 84880046627 scopus 로고    scopus 로고
    • Optimization of the ligature-induced periodontitis model in mice
    • Abe, T., and G. Hajishengallis. 2013. Optimization of the ligature-induced periodontitis model in mice. J. Immunol. Methods 394: 49-54.
    • (2013) J. Immunol. Methods , vol.394 , pp. 49-54
    • Abe, T.1    Hajishengallis, G.2
  • 35
    • 84869761067 scopus 로고    scopus 로고
    • Local complement-targeted intervention in periodontitis: Proofof-concept using a C5a receptor (CD88) antagonist
    • Abe, T., K. B. Hosur, E. Hajishengallis, E. S. Reis, D. Ricklin, J. D. Lambris, and G. Hajishengallis. 2012. Local complement-targeted intervention in periodontitis: proofof-concept using a C5a receptor (CD88) antagonist. J. Immunol. 189: 5442-5448.
    • (2012) J. Immunol. , vol.189 , pp. 5442-5448
    • Abe, T.1    Hosur, K.B.2    Hajishengallis, E.3    Reis, E.S.4    Ricklin, D.5    Lambris, J.D.6    Hajishengallis, G.7
  • 36
    • 84856591543 scopus 로고    scopus 로고
    • The RANKL-OPG system in clinical periodontology
    • Belibasakis, G. N., and N. Bostanci. 2012. The RANKL-OPG system in clinical periodontology. J. Clin. Periodontol. 39: 239-248.
    • (2012) J. Clin. Periodontol. , vol.39 , pp. 239-248
    • Belibasakis, G.N.1    Bostanci, N.2
  • 37
    • 0033094124 scopus 로고    scopus 로고
    • Relative proportions of mononuclear cell types in periodontal lesions analyzed by immunohistochemistry
    • Lappin, D. F., O. Koulouri, M. Radvar, P. Hodge, and D. F. Kinane. 1999. Relative proportions of mononuclear cell types in periodontal lesions analyzed by immunohistochemistry. J. Clin. Periodontol. 26: 183-189.
    • (1999) J. Clin. Periodontol. , vol.26 , pp. 183-189
    • Lappin, D.F.1    Koulouri, O.2    Radvar, M.3    Hodge, P.4    Kinane, D.F.5
  • 38
    • 0141855004 scopus 로고    scopus 로고
    • Automated kappa and lambda light chain mRNA expression for the assessment of B-cell clonality in cutaneous B-cell infiltrates: Its utility and diagnostic application
    • Magro, C., A. N. Crowson, P. Porcu, and G. J. Nuovo. 2003. Automated kappa and lambda light chain mRNA expression for the assessment of B-cell clonality in cutaneous B-cell infiltrates: its utility and diagnostic application. J. Cutan. Pathol. 30: 504-511.
    • (2003) J. Cutan. Pathol. , vol.30 , pp. 504-511
    • Magro, C.1    Crowson, A.N.2    Porcu, P.3    Nuovo, G.J.4
  • 40
    • 84865389455 scopus 로고    scopus 로고
    • Regulation of humoral immunity by complement
    • Carroll, M. C., and D. E. Isenman. 2012. Regulation of humoral immunity by complement. Immunity 37: 199-207.
    • (2012) Immunity , vol.37 , pp. 199-207
    • Carroll, M.C.1    Isenman, D.E.2
  • 41
    • 0028080099 scopus 로고
    • Regulation of terminal differentiation of human B-cells by IL-6
    • Chen-Kiang, S. 1995. Regulation of terminal differentiation of human B-cells by IL-6. Curr. Top. Microbiol. Immunol. 194: 189-198.
    • (1995) Curr. Top. Microbiol. Immunol. , vol.194 , pp. 189-198
    • Chen-Kiang, S.1
  • 42
    • 84906090500 scopus 로고    scopus 로고
    • Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8
    • Abe, T., J. Shin, K. Hosur, M. C. Udey, T. Chavakis, and G. Hajishengallis. 2014. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8. J. Immunol. 193: 1383-1391.
    • (2014) J. Immunol. , vol.193 , pp. 1383-1391
    • Abe, T.1    Shin, J.2    Hosur, K.3    Udey, M.C.4    Chavakis, T.5    Hajishengallis, G.6
  • 43
    • 34250205694 scopus 로고    scopus 로고
    • Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelialcell secretion of the cytokine April
    • He, B., W. Xu, P. A. Santini, A. D. Polydorides, A. Chiu, J. Estrella, M. Shan, A. Chadburn, V. Villanacci, A. Plebani, et al. 2007. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelialcell secretion of the cytokine APRIL. Immunity 26: 812-826.
    • (2007) Immunity , vol.26 , pp. 812-826
    • He, B.1    Xu, W.2    Santini, P.A.3    Polydorides, A.D.4    Chiu, A.5    Estrella, J.6    Shan, M.7    Chadburn, A.8    Villanacci, V.9    Plebani, A.10
  • 44
    • 84885967227 scopus 로고    scopus 로고
    • Saliva and serum levels of B-cell activating factors and tumor necrosis factor-A in patients with periodontitis
    • Gümüş, P., N. Nizam, D. F. Lappin, and N. Buduneli. 2014. Saliva and serum levels of B-cell activating factors and tumor necrosis factor-A in patients with periodontitis. J. Periodontol. 85: 270-280.
    • (2014) J. Periodontol. , vol.85 , pp. 270-280
    • Gümüş, P.1    Nizam, N.2    Lappin, D.F.3    Buduneli, N.4
  • 45
    • 77955343903 scopus 로고    scopus 로고
    • Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice
    • Scapini, P., Y. Hu, C. L. Chu, T. S. Migone, A. L. Defranco, M. A. Cassatella, and C. A. Lowell. 2010. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. J. Exp. Med. 207: 1757-1773.
    • (2010) J. Exp. Med. , vol.207 , pp. 1757-1773
    • Scapini, P.1    Hu, Y.2    Chu, C.L.3    Migone, T.S.4    DeFranco, A.L.5    Cassatella, M.A.6    Lowell, C.A.7
  • 46
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • Miossec, P., and J. K. Kolls. 2012. Targeting IL-17 and TH17 cells in chronic inflammation. Nat. Rev. Drug Discov. 11: 763-776.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 48
    • 19944428744 scopus 로고    scopus 로고
    • Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: Implications for inflammatory diseases
    • Scapini, P., A. Carletto, B. Nardelli, F. Calzetti, V. Roschke, F. Merigo, N. Tamassia, S. Pieropan, D. Biasi, A. Sbarbati, et al. 2005. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood 105: 830-837.
    • (2005) Blood , vol.105 , pp. 830-837
    • Scapini, P.1    Carletto, A.2    Nardelli, B.3    Calzetti, F.4    Roschke, V.5    Merigo, F.6    Tamassia, N.7    Pieropan, S.8    Biasi, D.9    Sbarbati, A.10
  • 50
    • 80755152588 scopus 로고    scopus 로고
    • Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease
    • DOI: 10.3402/jom.v2i0.5532
    • Kajiya, M., G. Giro, M. A. Taubman, X. Han, M. P. Mayer, and T. Kawai. 2010. Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease. J. Oral Microbiol. 2: 5532. DOI: 10.3402/jom.v2i0.5532.
    • (2010) J. Oral Microbiol. , vol.2 , pp. 5532
    • Kajiya, M.1    Giro, G.2    Taubman, M.A.3    Han, X.4    Mayer, M.P.5    Kawai, T.6
  • 51
    • 0034305404 scopus 로고    scopus 로고
    • Some effects of nonsurgical therapy on gingival inflammatory cell subsets in patients with adult and early-onset periodontitis
    • Kleinfelder, J. W., D. E. Lange, and W. Böcker. 2000. Some effects of nonsurgical therapy on gingival inflammatory cell subsets in patients with adult and early-onset periodontitis. J. Periodontol. 71: 1561-1566.
    • (2000) J. Periodontol. , vol.71 , pp. 1561-1566
    • Kleinfelder, J.W.1    Lange, D.E.2    Böcker, W.3
  • 52
    • 84888040082 scopus 로고    scopus 로고
    • Gingival crevicular fluid and serum levels of April, BAFF and TNF-alpha in rheumatoid arthritis and osteoporosis patients with periodontal disease
    • Gümüş, P., E. Buduneli, B. Biyikoglu, K. Aksu, F. Saraç, N. Buduneli, and D. F. Lappin. 2013. Gingival crevicular fluid and serum levels of APRIL, BAFF and TNF-alpha in rheumatoid arthritis and osteoporosis patients with periodontal disease. Arch. Oral Biol. 58: 1302-1308.
    • (2013) Arch. Oral Biol. , vol.58 , pp. 1302-1308
    • Gümüş, P.1    Buduneli, E.2    Biyikoglu, B.3    Aksu, K.4    Saraç, F.5    Buduneli, N.6    Lappin, D.F.7
  • 54
    • 84881093916 scopus 로고    scopus 로고
    • Targeting the BLyS-April signaling pathway in SLE
    • La Cava, A. 2013. Targeting the BLyS-APRIL signaling pathway in SLE. Clin. Immunol. 148: 322-327.
    • (2013) Clin. Immunol. , vol.148 , pp. 322-327
    • La Cava, A.1
  • 55
    • 84879107691 scopus 로고    scopus 로고
    • New biologic therapy for systemic lupus erythematosus
    • Ding, H. J., and C. Gordon. 2013. New biologic therapy for systemic lupus erythematosus. Curr. Opin. Pharmacol. 13: 405-412.
    • (2013) Curr. Opin. Pharmacol. , vol.13 , pp. 405-412
    • Ding, H.J.1    Gordon, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.