An excess of the proinflammatory cytokines IFN-γ and IL- 12 Impairs the development of the memory CD8+ T cell response to chlamydia trachomatis

Journal of Immunology

Volumn 195, Issue 4, 2015, Pages 1665-1675

  Zhang, Xuqing ^a   Starnbach, Michael N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CYTOKINE; FAS ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 2; INTERLEUKIN 2 ALPHA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 6; INTERLEUKIN 7; L SELECTIN; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; AUTACOID; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; BACTERIAL LOAD; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL FATE; CELL MATURATION; CELL STIMULATION; CHLAMYDIA TRACHOMATIS; COMPLEX FORMATION; CONTROLLED STUDY; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; ANIMAL; CHLAMYDIASIS; DISEASE MODEL; GENE EXPRESSION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; MICROBIOLOGY; MUCOSA; SPLEEN; TRANSGENIC MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INFLAMMATION MEDIATORS; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-2; MICE; MICE, TRANSGENIC; MUCOUS MEMBRANE; PHENOTYPE; SIGNAL TRANSDUCTION; SPLEEN; T-BOX DOMAIN PROTEINS;

EID: 84938919463     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500457     Document Type: Article

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