Role of ubiquitin and the HPV E6 oncoprotein in E6APmediated ubiquitination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 32, 2015, Pages 9872-9877

  Mortensen, Franziska ^a   Schneider, Daniel ^a   Barbic, Tanja ^a   Sladewska Marquardt, Anna ^a   Kühnle, Simone ^a,b   Marx, Andreas ^a   Scheffner, Martin ^a   Ciechanover, Aaron ^c  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Angelman syndrome; E6 oncoprotein; E6AP UBE3A; Human papillomavirus; Ubiquitin

Indexed keywords

ISOLEUCINE; LEUCINE; PROTEIN E6; RING1B PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYSTEINE; PEPTIDE; PROTEIN BINDING; UBE2D2 PROTEIN, HUMAN; UBE2L3 PROTEIN, HUMAN; UBE3A PROTEIN, HUMAN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; WART VIRUS; ALLOSTERISM; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMICAL PHENOMENA; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

HUMAN PAPILLOMAVIRUS; PAPILLOMAVIRIDAE;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BIOCATALYSIS; CELL LINE, TUMOR; CYSTEINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84938915433     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1505923112     Document Type: Article

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