-
1
-
-
0024394549
-
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
-
Andersson, S., D. L. Davis, H. Dahlback, H. Jornvall, and D. W. Russell. 1989. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem. 264:8222-8229.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 8222-8229
-
-
Andersson, S.1
Davis, D.L.2
Dahlback, H.3
Jornvall, H.4
Russell, D.W.5
-
2
-
-
0025838391
-
Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells
-
Band, V., J. A. De Caprio, L. Delmolino, V. Kulesa, and R. Sager. 1991. Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells. J. Virol. 65:6671-6676.
-
(1991)
J. Virol.
, vol.65
, pp. 6671-6676
-
-
Band, V.1
De Caprio, J.A.2
Delmolino, L.3
Kulesa, V.4
Sager, R.5
-
3
-
-
0031058283
-
Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells
-
Beer-Romero, P., S. Glass, and M. Rolfe. 1997. Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells. Oncogene 14: 595-602.
-
(1997)
Oncogene
, vol.14
, pp. 595-602
-
-
Beer-Romero, P.1
Glass, S.2
Rolfe, M.3
-
4
-
-
0031010398
-
Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HsIV by a new class of inhibitors
-
Bogyo, M., J. S. McMaster, M. Gaczynska, D. Tortorella, A. L. Goldberg, and H. Ploegh. 1997. Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HsIV by a new class of inhibitors. Proc. Natl. Acad. Sci. USA 94:6629-6634.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6629-6634
-
-
Bogyo, M.1
McMaster, J.S.2
Gaczynska, M.3
Tortorella, D.4
Goldberg, A.L.5
Ploegh, H.6
-
5
-
-
0029834371
-
E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway
-
Boyer, S. N., D. E. Wazer, and V. Band. 1996. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res. 56:4620-4624.
-
(1996)
Cancer Res.
, vol.56
, pp. 4620-4624
-
-
Boyer, S.N.1
Wazer, D.E.2
Band, V.3
-
6
-
-
0025950547
-
The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex
-
Dostatni, N., P. F. Lambert, R. Sousa, J. Ham, P. M. Howley, and M. Yaniv. 1991. The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes Dev. 5:1657-1671.
-
(1991)
Genes Dev.
, vol.5
, pp. 1657-1671
-
-
Dostatni, N.1
Lambert, P.F.2
Sousa, R.3
Ham, J.4
Howley, P.M.5
Yaniv, M.6
-
7
-
-
0028824891
-
Suppression of cellular proliferation by the papillomavirus E2 protein
-
Downanick, J. J., A. A. McBride, and P. M. Howley. 1995. Suppression of cellular proliferation by the papillomavirus E2 protein. J. Virol. 69:7791-7799.
-
(1995)
J. Virol.
, vol.69
, pp. 7791-7799
-
-
Downanick, J.J.1
McBride, A.A.2
Howley, P.M.3
-
8
-
-
0024535228
-
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
-
Dyson, N., P. M. Howley, K. Munger, and E. Harlow. 1989. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937.
-
(1989)
Science
, vol.243
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Munger, K.3
Harlow, E.4
-
9
-
-
0030695025
-
A complex of Cdc4p, Skplp. and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Siclp
-
Feldman, R. M., C. C. Correll, K. B. Kaplan, and R. J. Deshaies. 1997. A complex of Cdc4p, Skplp. and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Siclp. Cell 91:221-230.
-
(1997)
Cell
, vol.91
, pp. 221-230
-
-
Feldman, R.M.1
Correll, C.C.2
Kaplan, K.B.3
Deshaies, R.J.4
-
10
-
-
0032520060
-
Human fibroblasts expressing the human papillomavirus E6 gene are deficient in global genomic nucleotide excision repair and sensitive to ultraviolet irradiation
-
Ford, J. M., E. L. Baron, and P. C. Hanawalt. 1998. Human fibroblasts expressing the human papillomavirus E6 gene are deficient in global genomic nucleotide excision repair and sensitive to ultraviolet irradiation. Cancer Res. 58:599-603.
-
(1998)
Cancer Res.
, vol.58
, pp. 599-603
-
-
Ford, J.M.1
Baron, E.L.2
Hanawalt, P.C.3
-
11
-
-
0342948594
-
Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells
-
Francis, D. A., S. I. Schmid, and P. M. Howley. 2000. Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells. J. Virol. 74:2679-2686.
-
(2000)
J. Virol.
, vol.74
, pp. 2679-2686
-
-
Francis, D.A.1
Schmid, S.I.2
Howley, P.M.3
-
12
-
-
0033529757
-
Ubiquitin-dependent degradation of multiple F-box proteins by an aulocatalytic mechanism
-
Galan, J. M., and M. Peter. 1999. Ubiquitin-dependent degradation of multiple F-box proteins by an aulocatalytic mechanism. Proc. Natl. Acad. Sci. USA 96:9124-9129.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9124-9129
-
-
Galan, J.M.1
Peter, M.2
-
13
-
-
0032952586
-
The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation
-
Gao, Q., S. Srinivasan, S. N. Boyer, D. E. Wazer, and V. Band. 1999. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. Mol. Cell. Biol. 19:733-744.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 733-744
-
-
Gao, Q.1
Srinivasan, S.2
Boyer, S.N.3
Wazer, D.E.4
Band, V.5
-
14
-
-
0031957756
-
Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines
-
Goodwin, E. C., L. K. Naeger, D. E. Breiding, E. J. Androphy, and D. DiMaio. 1998. Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines. J. Virol. 72:3925-3934.
-
(1998)
J. Virol.
, vol.72
, pp. 3925-3934
-
-
Goodwin, E.C.1
Naeger, L.K.2
Breiding, D.E.3
Androphy, E.J.4
DiMaio, D.5
-
15
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C., C. M. Counter, A. S. Lundberg, R. L. Beijersbergen, M. W. Brooks, and R. A. Weinberg. 1999. Creation of human tumour cells with defined genetic elements. Nature 400:464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
16
-
-
0033598775
-
Ubiquitin-mediated degradation of active Src tyrosine kinase
-
Harris, K. F., I. Shoji, E. M. Cooper, S. Kumar, H. Oda, and P. M. Howley. 1999. Ubiquitin-mediated degradation of active Src tyrosine kinase. Proc. Natl. Acad. Sci. USA 96:13738-13743.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13738-13743
-
-
Harris, K.F.1
Shoji, I.2
Cooper, E.M.3
Kumar, S.4
Oda, H.5
Howley, P.M.6
-
17
-
-
0024804363
-
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes
-
Hawley-Nelson, P., K. H. Vousden, N. L. Hubbert, D. R. Lowy, and J. T. Schiller. 1989. HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes. EMBO J. 8:3905-3910.
-
(1989)
EMBO J.
, vol.8
, pp. 3905-3910
-
-
Hawley-Nelson, P.1
Vousden, K.H.2
Hubbert, N.L.3
Lowy, D.R.4
Schiller, J.T.5
-
19
-
-
0032741446
-
Structure of an E6AP-UbcH7 complex: Insights into ubiquitination by the E2-E3 enzyme cascade
-
Huang, L., E. Kinnucan, G. Wang, S. Beaudenon, P. M. Howley, J. M. Huibregtse, and N. P. Pavletich. 1999. Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science 286:1321-1326.
-
(1999)
Science
, vol.286
, pp. 1321-1326
-
-
Huang, L.1
Kinnucan, E.2
Wang, G.3
Beaudenon, S.4
Howley, P.M.5
Huibregtse, J.M.6
Pavletich, N.P.7
-
20
-
-
0025191335
-
Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18
-
Hudson, J. B., M. A. Bedell, D. J. McCance, and L. A. Laiminis. 1990. Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18. J. Virol. 64:519-526.
-
(1990)
J. Virol.
, vol.64
, pp. 519-526
-
-
Hudson, J.B.1
Bedell, M.A.2
McCance, D.J.3
Laiminis, L.A.4
-
21
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse, J. M., M. Scheffer, S. Beaudenon, and P. M. Howley. 1995. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 92:2563-2567.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffer, M.2
Beaudenon, S.3
Howley, P.M.4
-
22
-
-
0027396829
-
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53
-
Huibregtse, J. M., M. Scheffner, and P. M. Howley. 1993 Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol. Cell. Biol. 13:775-784.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 775-784
-
-
Huibregtse, J.M.1
Scheffner, M.2
Howley, P.M.3
-
23
-
-
0027169680
-
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins
-
Huibregtse, J. M., M. Scheffner, and P. M. Howley. 1993. Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol. Cell. Biol. 13:4918-4927.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4918-4927
-
-
Huibregtse, J.M.1
Scheffner, M.2
Howley, P.M.3
-
24
-
-
0030045822
-
Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene
-
Hwang, E. S., L. K. Naeger, and D. DiMaio. 1996. Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene. Oncogene 12:795-803.
-
(1996)
Oncogene
, vol.12
, pp. 795-803
-
-
Hwang, E.S.1
Naeger, L.K.2
DiMaio, D.3
-
25
-
-
0027158747
-
Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene
-
Hwang, E. S., D. J. D. Riese, J. Settleman, L. A. Nilson, J. Honig, S. Flynn, and D. DiMaio. 1993. Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene. J. Virol. 67:3720-3729.
-
(1993)
J. Virol.
, vol.67
, pp. 3720-3729
-
-
Hwang, E.S.1
Riese, D.J.D.2
Settleman, J.3
Nilson, L.A.4
Honig, J.5
Flynn, S.6
DiMaio, D.7
-
26
-
-
0031438309
-
Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis
-
Jones, D. L., D. A. Thompson, and K. Munger. 1997. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis. Virology 239:97-107.
-
(1997)
Virology
, vol.239
, pp. 97-107
-
-
Jones, D.L.1
Thompson, D.A.2
Munger, K.3
-
27
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono, T., S. A. Foster, J. I. Koop, J. K. McDougall, D. A. Galloway, and A. J. Klingelhutz. 1998. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396:84-88
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
28
-
-
0030774987
-
Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein
-
Kiyono, T., A. Hiraiwa, M. Fujita, Y. Hayashi, T. Akiyama, and M. Ishibashi. 1997. Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. PRK. Natl. Acad. Sci. USA 94:11612-11616.
-
(1997)
PRK. Natl. Acad. Sci. USA
, vol.94
, pp. 11612-11616
-
-
Kiyono, T.1
Hiraiwa, A.2
Fujita, M.3
Hayashi, Y.4
Akiyama, T.5
Ishibashi, M.6
-
29
-
-
0030008177
-
Telomerase activation by the E6 gene product of human papillomavirus type 16
-
Klingelhutz, A. J., S. A. Foster, and J. K. McDougall. 1996. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 380:79-82.
-
(1996)
Nature
, vol.380
, pp. 79-82
-
-
Klingelhutz, A.J.1
Foster, S.A.2
McDougall, J.K.3
-
30
-
-
0032545368
-
E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the uhiquitination pathway by a novel motif, the L2G box
-
Kuhne, C., and L. Banks. 1998. E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the uhiquitination pathway by a novel motif, the L2G box. J. Biol. Chem. 273:34302-34309.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34302-34309
-
-
Kuhne, C.1
Banks, L.2
-
31
-
-
0030908874
-
Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity
-
Kumar, S., W. H. Kao, and P. M. Howley. 1997. Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J. Biol. Chem. 272:13548-13554.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13548-13554
-
-
Kumar, S.1
Kao, W.H.2
Howley, P.M.3
-
32
-
-
0033603339
-
Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination
-
Kumar, S., A. L. Talis, and P. M. Howley. 1999. Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. J. Biol. Chem. 274:18785-18792.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18785-18792
-
-
Kumar, S.1
Talis, A.L.2
Howley, P.M.3
-
33
-
-
0032816001
-
Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells
-
Liu, Y., J. J. Chen, Q. Gao, S. Dalal, Y. Hong, C. P. Mansur, V. Band, and E. J. Androphy. 1999. Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. J. Virol. 73:7297-7307.
-
(1999)
J. Virol.
, vol.73
, pp. 7297-7307
-
-
Liu, Y.1
Chen, J.J.2
Gao, Q.3
Dalal, S.4
Hong, Y.5
Mansur, C.P.6
Band, V.7
Androphy, E.J.8
-
34
-
-
0028096801
-
Cloning and characterization of hdlg: The human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1
-
Lue, R. A., S. M. Marfatia, D. Branton, and A. H. Chishti. 1994. Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1. Proc. Natl. Acad. Sci. USA 91:9818-9822.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9818-9822
-
-
Lue, R.A.1
Marfatia, S.M.2
Branton, D.3
Chishti, A.H.4
-
35
-
-
0028269240
-
Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23
-
Masutani, C., K. Sugasawa, J. Yanagisawa, T. Sonoyama, M. Ui, T. Enomoto, K. Takio, K. Tanaka, P. J. van der Spek, D. Bootsma, et al. 1994. Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. EMBO J. 13:1831-1843.
-
(1994)
EMBO J.
, vol.13
, pp. 1831-1843
-
-
Masutani, C.1
Sugasawa, K.2
Yanagisawa, J.3
Sonoyama, T.4
Ui, M.5
Enomoto, T.6
Takio, K.7
Tanaka, K.8
Van Der Spek, P.J.9
Bootsma, D.10
-
36
-
-
0024428508
-
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
-
Munger, K., W. C. Phelps, V. Bubb, P. M. Howley, and R. Schlegel. 1989. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol. 63:4417-4421.
-
(1989)
J. Virol.
, vol.63
, pp. 4417-4421
-
-
Munger, K.1
Phelps, W.C.2
Bubb, V.3
Howley, P.M.4
Schlegel, R.5
-
37
-
-
0030043724
-
Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1 ) and characterization of their interaction with E6-AP and RSP5
-
Nuber, U., S. Schwarz, P. Kaiser, R. Schneider, and M. Scheffner. 1996. Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1 ) and characterization of their interaction with E6-AP and RSP5. J. Biol. Chem. 271:2795-2800.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2795-2800
-
-
Nuber, U.1
Schwarz, S.2
Kaiser, P.3
Schneider, R.4
Scheffner, M.5
-
38
-
-
0032525905
-
The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate
-
Nuber, U., S. E. Schwarz, and M. Scheffner. 1998. The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate. Eur. J. Biochem. 254:643-649.
-
(1998)
Eur. J. Biochem.
, vol.254
, pp. 643-649
-
-
Nuber, U.1
Schwarz, S.E.2
Scheffner, M.3
-
39
-
-
0033578418
-
Regulation of the src family tyrosine kinase hlk through E6AP-mediated uhiquitination
-
Oda, H., S. Kumar, and P. M. Howley. 1999. Regulation of the src family tyrosine kinase hlk through E6AP-mediated uhiquitination. Proc. Natl. Acad. Sci. USA 96:9557-9562.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9557-9562
-
-
Oda, H.1
Kumar, S.2
Howley, P.M.3
-
40
-
-
0025311444
-
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
-
Romanczuk, H., F. Thierry, and P. M. Howley. 1990. Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J. Virol. 64:2849-2859.
-
(1990)
J. Virol.
, vol.64
, pp. 2849-2859
-
-
Romanczuk, H.1
Thierry, F.2
Howley, P.M.3
-
41
-
-
0028607435
-
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
-
Scheffner, M., J. M. Huibregtse, and P. M. Howley. 1994. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc. Natl. Acad. Sci. USA 91:8797-8801.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8797-8801
-
-
Scheffner, M.1
Huibregtse, J.M.2
Howley, P.M.3
-
42
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
Scheffner, M., J. M. Huibregtse, R. D. Vierstra, and P. M. Howley. 1993. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75:495-505.
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
43
-
-
0028898424
-
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
-
Scheffner, M., U. Nuber, and J. M. Huibregtse. 1995. Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 373:81-83.
-
(1995)
Nature
, vol.373
, pp. 81-83
-
-
Scheffner, M.1
Nuber, U.2
Huibregtse, J.M.3
-
44
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 53:1129-1136.
-
(1990)
Cell
, vol.53
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
45
-
-
0026012525
-
The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture
-
Sedman, S. A., M. S. Barbosa, W. C. Vass, N. L. Hubbert, J. A. Haas, D. R. Lowy, and J. T. Schiller. 1991. The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture. J. Virol. 65:4860-4866.
-
(1991)
J. Virol.
, vol.65
, pp. 4860-4866
-
-
Sedman, S.A.1
Barbosa, M.S.2
Vass, W.C.3
Hubbert, N.L.4
Haas, J.A.5
Lowy, D.R.6
Schiller, J.T.7
-
46
-
-
0029968641
-
Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16
-
Sherman, L., and R. Schlegel. 1996. Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16. J. Virol. 70:3269-3279.
-
(1996)
J. Virol.
, vol.70
, pp. 3269-3279
-
-
Sherman, L.1
Schlegel, R.2
-
47
-
-
0033596977
-
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1
-
Skowyra, D., D. M. Koepp, T. Kamura, M. N. Conrad, R. C. Conaway, J. W. Conaway, S. J. Elledge, and J. W. Harper. 1999. Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284: 662-665.
-
(1999)
Science
, vol.284
, pp. 662-665
-
-
Skowyra, D.1
Koepp, D.M.2
Kamura, T.3
Conrad, M.N.4
Conaway, R.C.5
Conaway, J.W.6
Elledge, S.J.7
Harper, J.W.8
-
48
-
-
0033028610
-
The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals
-
Song, S., H. C. Pitot, and P. F. Lambert. 1999. The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals. J. Virol. 73:5887-5893.
-
(1999)
J. Virol.
, vol.73
, pp. 5887-5893
-
-
Song, S.1
Pitot, H.C.2
Lambert, P.F.3
-
49
-
-
0025924668
-
Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter
-
Spalholz, B. A., S. B. Vande Pol, and P. M. Howley. 1991. Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter. J. Virol. 65:743-753.
-
(1991)
J. Virol.
, vol.65
, pp. 743-753
-
-
Spalholz, B.A.1
Vande Pol, S.B.2
Howley, P.M.3
-
50
-
-
0029756780
-
p53-independent growth regulation of cervical cancer cells by the papillomavirus E6 oncogene
-
Spitkovsky, D., F. Aengeneyndt, J. Braspenning, and M. von Knebel Doeberitz. 1996. p53-independent growth regulation of cervical cancer cells by the papillomavirus E6 oncogene. Oncogene 13:1027-1035.
-
(1996)
Oncogene
, vol.13
, pp. 1027-1035
-
-
Spitkovsky, D.1
Aengeneyndt, F.2
Braspenning, J.3
Von Knebel Doeberitz, M.4
-
51
-
-
0027513556
-
Human papillomavirus type 16 E6 gene cooperates with EJ-ras to immortalize primary mouse cells
-
Storey, A., and L. Banks. 1993. Human papillomavirus type 16 E6 gene cooperates with EJ-ras to immortalize primary mouse cells. Oncogene 8:919-924.
-
(1993)
Oncogene
, vol.8
, pp. 919-924
-
-
Storey, A.1
Banks, L.2
-
52
-
-
0030688064
-
Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity
-
Sugasawa, K., J. M. Ng, C. Masutani, T. Maekawa, A. Uchida, P. J. van der Spek, A. P. Eker, S. Rademakers, C. Visser, A. Aboussekhra, R. D. Wood, F. Hanaoka, D. Bootsma, and J. H. Hoeijmakers. 1997. Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity. Mol. Cell. Biol. 17:6924-6931.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6924-6931
-
-
Sugasawa, K.1
Ng, J.M.2
Masutani, C.3
Maekawa, T.4
Uchida, A.5
Van Der Spek, P.J.6
Eker, A.P.7
Rademakers, S.8
Visser, C.9
Aboussekhra, A.10
Wood, R.D.11
Hanaoka, F.12
Bootsma, D.13
Hoeijmakers, J.H.14
-
53
-
-
0032513114
-
The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells
-
Talis, A. L., J. M. Huibregtse, and P. M. Howley. 1998. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J. Biol. Chem. 273:6439-6445.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6439-6445
-
-
Talis, A.L.1
Huibregtse, J.M.2
Howley, P.M.3
-
54
-
-
0026061128
-
Functional analysis of E2-mediated repression of the HPV18 P105 promoter
-
Thierry, F., and P. M. Howley. 1991. Functional analysis of E2-mediated repression of the HPV18 P105 promoter. New Biol. 3:90-100.
-
(1991)
New Biol.
, vol.3
, pp. 90-100
-
-
Thierry, F.1
Howley, P.M.2
-
55
-
-
0023441712
-
The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region
-
Thierry, F., and M. Yaniv. 1987. The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region. EMBO J. 6:3391-3397.
-
(1987)
EMBO J.
, vol.6
, pp. 3391-3397
-
-
Thierry, F.1
Yaniv, M.2
-
56
-
-
0031001560
-
The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton
-
Tong, X., and P. M. Howley. 1997. The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 94:4412-4417.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4412-4417
-
-
Tong, X.1
Howley, P.M.2
-
57
-
-
0027966390
-
Paxillin: A cytoskeletal target for tyrosine kinases
-
Turner, C. E. 1994. Paxillin: a cytoskeletal target for tyrosine kinases. Bioessays 16:47-52.
-
(1994)
Bioessays
, vol.16
, pp. 47-52
-
-
Turner, C.E.1
-
58
-
-
0032495590
-
Association of bovine papillomavirus type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif
-
Vande Pol, S. B., M. C. Brown, and C. E. Turner. 1998. Association of bovine papillomavirus type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif. Oncogene 16:43-52.
-
(1998)
Oncogene
, vol.16
, pp. 43-52
-
-
Vande Pol, S.B.1
Brown, M.C.2
Turner, C.E.3
-
59
-
-
0025271203
-
Association of human papillomavirus types 16 and 18 E6 proteins with p53
-
Werness, B. A., A. J. Levine, and P. M. Howley. 1990. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248:76-79.
-
(1990)
Science
, vol.248
, pp. 76-79
-
-
Werness, B.A.1
Levine, A.J.2
Howley, P.M.3
-
60
-
-
0026758384
-
Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein
-
Winokur, P. L., and A. A. McBride. 1992. Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein. EMBO J. 11:4111-4118.
-
(1992)
EMBO J.
, vol.11
, pp. 4111-4118
-
-
Winokur, P.L.1
McBride, A.A.2
-
61
-
-
0025941465
-
The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions
-
Woods, D. F., and P. J. Bryant. 1991. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell 66:451-464.
-
(1991)
Cell
, vol.66
, pp. 451-464
-
-
Woods, D.F.1
Bryant, P.J.2
-
62
-
-
0031569842
-
The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing
-
Yamamoto, Y., J. M. Huibregtse, and P. M. Howley. 1997. The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing. Genomics 41:263-266.
-
(1997)
Genomics
, vol.41
, pp. 263-266
-
-
Yamamoto, Y.1
Huibregtse, J.M.2
Howley, P.M.3
-
63
-
-
0032215237
-
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases
-
Zhou, P., and P. M. Howley. 1998. Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol. Cell 2:571-580.
-
(1998)
Mol. Cell
, vol.2
, pp. 571-580
-
-
Zhou, P.1
Howley, P.M.2
-
64
-
-
0030577120
-
Papillomavirus infections - A major cause of human cancers
-
zur Hausen, H. 1996. Papillomavirus infections - a major cause of human cancers. Biochim. Biophys. Acta 1288:F55-78.
-
(1996)
Biochim. Biophys. Acta
, vol.1288
-
-
Zur Hausen, H.1
|